Frank H. Gafford IV, MD, Cardiology, Saint Louis, MO, Mercy Hospital South


Cardiology Saint Louis, MO

Echocardiography, Nuclear Cardiology, Non-Invasive Cardiology

Solo noninvasive cardiology practice at Frank Gafford MD, PC

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  • I am a board-certified, noninvasive cardiologist in solo private practice in South St. Louis County. I did my Cardiology fellowship at Washington University/Barnes Hospital. I am on the active medical staff of St. Anthony’s Medical Center | Mercy. Early in my
    career I was a Critical Care Physician and was board-certified in Critical Care Medicine between 1991-2001. I did not recertify in CCM after 2001 as I had “morphed” into an exclusively Cardiology practice. I am a Fellow of the American College of Cardiology and also of the American College of Chest Physicians.

    I was born and raised in Birmingham, Alabama. My wife (also an Alabamian) and I have lived in STL since 1974 and raised our family here. Of course, neither of us can ever hope to be real St. Louisans as we did not attend high school in St. Louis. Our three children went to high school in STL, but were not born in Missouri. My grandmother did raise the flag at the Swedish Pavilion when she was eight years old at the STL World’s Fair, which was also attended by many notable people including Geronimo (native American Apache leader), President Theodore Roosevelt, Mary E Walker, Annie Malone, T.S. Eliot (native St.Louisan so of course he was there), Guglielmo Marconi, Booker T Washington, Thomas Edison, Helen Keller, Scott Joplin, Will Rogers, William Howard Taft and Jack Daniels (whose Tennessee Whiskey won the Gold Medal for the World’s finest Whiskey). Also, my mother was born in St Louis but moved away as a young child, severing any STL roots for me.

Education & Training

  • Washington University
    Washington UniversityFellowship, Cardiovascular Disease, 1974 - 1976
  • University of California San Diego
    University of California San DiegoResidency, Internal Medicine, 1972 - 1974
  • University of Alabama School of Medicine
    University of Alabama School of MedicineClass of 1972, MD
  • Johns Hopkins UniversityBA, Biology/Pre-Med, 1964 - 1968

Certifications & Licensure

  • MO State Medical License
    MO State Medical License 1974 - 2020
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

  • Fellow (FACC) American College of Cardiology, 1984
  • Fellow (FCCP) College of Chest Physicians, 1984
  • Dorsey Scholar UAB School of Medicine, 1969-1972
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Publications & Presentations


Journal Articles

  • NIH Consensus Report on Critical Care Medicine  
    Gafford FH, Crit Care Med/JAMA, 1/12/1983
  • Pharmacologic Support for the Failing Heart in the ICU Patient  
    Gafford FH, Ayres SM, J Cardiovascular Med, 1/1/1984
  • Care of the Critically Ill  
    Gafford FH, 1/1/1987
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Books/Book Chapters


  • Implementation of a Critical Care Program in a Community Teaching Hospital
    Gafford FH, Taylor RW, Crit Care Med, 11th Annual Society of Critical Care Medicine Meeting, 1/1/1982
  • Conjoint Critical Care Medicine Fellowships
    Gafford FH, Ayres SM, Crit Care Med, 13th Annual SCCM Educational and Scientific Symposium, 1/29/1984
  • Shock Associated with Acute Myocardial Infarction: Pathophysiology, Diagnosis, Treatment and Prevention
    Gafford FH, Ayres SM, Baylor College of Medicine Cardiology series, 1/1/1985
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  • A Cost Effectiveness Study Design Applied to Evaluating Pulmonary Artery Catheters 
    Cowden WL, Huber GS, Gafford FH, Health Industry Manufacturer’s Association (HIMA) publication


  • Member, SAMC IRB
  • Member, Pharmacy and Therapeutics

Professional Memberships

Hospital Affiliations