Gary Hammer, MD

Gary Hammer, MD, PhD

Endocrinology Ann Arbor, MI

Professor of Internal Medicine; Molecular & Integrative Physiology; Cell & Developmental Biology - University Mich Medical School


Office Address

  • 109 Zina Pitcher Place
    1528 BSRB - University of Michigan
    Ann Arbor, MI 48109
    Phone: (734) 615-2421

Gary Hammer, MD, PhD

Endocrinology Ann Arbor, MI

Professor of Internal Medicine; Molecular & Integrative Physiology; Cell & Developmental Biology - University Mich Medical School

Summary

  • Gary D. Hammer, M.D., Ph.D. is Professor in the Departments of Internal Medicine (Metabolism, Endocrinology & Diabetes), Cell & Developmental Biology, and Molecular & Integrative Physiology at the University of Michigan. He serves as Director of the Endocrine Oncology Program in the Comprehensive Cancer Center where he holds the Millie Schembechler Professorship in Adrenal Cancer. He is also Director of the Center for Organogenesis that focuses on organ-specific problems spanning developmental disorders to cancer. He received the Jerome Conn Award for Outstanding Research in Internal Medicine and the Endocrine Society Edwin B. Astwood Award for Outstanding Research in Endocrinology. He is a member of the American Society for Clinical Investigation and Association of American Physicians. He is Editor of three textbooks: Adrenocortical Carcinoma: Basic Science and Clinical Concepts (Springer 2011), Pathophysiology of Disease: An Introduction to Clinical Medicine (Harper Row, 2014) and Genetics Steroid Disorders (Elsevier, 2014). He has served the Endocrine Society in a variety of roles including Chair of Student Affairs Committee, Chair of Mentoring Task Force, Basic Science Chair of Annual Meeting Trainee Day and most recently Council Member at Large and a Society Ambassador to King Edward Memorial Hospital in Mumbai India as part of the 2012 inaugural Endocrine Society Ambassador Exchange Program. Research projects in his own laboratory are aimed at elucidating the mechanisms by which growth factor signaling and transcriptional programs initiate adrenal-specific growth and differentiation with an emphasis on dysregulated stem cells in development and cancer. He is a co-founder of the company Atterocor that focuses on therapies for adrenal cancer. Collaborative work with colleagues has led to the development of international therapeutic trials with biological-based therapies for adrenal cancer that target the molecular defects in cancer.

Clinical Specialties & Interests

  • Endocrinology: General Endocrinology, Adrenal Disease
  • Clinical Interests: Adrenal Gland Neoplasms; Adrenal Cortex; Adrenal Development

Education & Training

  • UCSFUCSF
  • UCSFUCSF
  • Tufts University Sackler School of Graduate Biomedical Sciences
  • Tufts University School of MedicineTufts University School of Medicine
  • University of Vermont

Certifications & Licensure

  • MI State Medical LicenseMI State Medical License2000 - 2016
  • American Board of Internal MedicineEndocrinology, Diabetes and Metabolism

    Awards, Honors, & Recognition

    • Elected MemberAmerican Association of Physicians, 2012
    • The One Hundred, InducteeMassachusetts General Hospital Cancer Center, 2014
    • America's Top DoctorsCastle Connolly, 2014, 2013, 2012, 2011

    Publications & Presentations

    PubMed

    Journal Articles

    • Withanolides Are Potent Novel Targeted Therapeutic Agents against Adrenocortical Carcinomas  Subramanian C, Zhang H, Gallagher R, Hammer G, Timmermann B. and Cohen M, World Journal of Surgery, 6/1/2014
    • Abiraterone Acetate Added to Physiologic Hydrocortisone and Fludrocortisone Acetate Normalizes Androgen Excess in Adult Women With Classic 21-Hydroxylase Deficiency  Auchus RJ, Buschur EO, Chang AY, Hammer GD, Ramm C, Madrigal M, Wang G, Gonzalez M, Xu S, Smit JW, Jiao J and Yu MK, Journal of Clinical Endocrinology and Metabolism, 4/29/2014
    • Prognostic Role of Overt Hypercortisolism in Completely Operated Patients with Adrenocortical Cancer  Berruti A, Fassnacht M, Haak H, Else T, Baudin E, Sperone P, Kroiss M, Kerkhofs T, Williams AR, Ardito A, Leboulleux S, Volante M, Deutschbein T, Feelders R, Ronchi C,..., Eur Urol, 4/1/2014

    Books/Book Chapters

    • Pathophysiology of Disease: An Introduction to Clinical Medicine  

      Editors: Hammer GD and McPhee SJ.LANGE
      Edition Seve,2014
    • CANCER: Principles & Practice of Oncology Chapter: Adrenal Tumors 
      Lirov R, Else T, Lerario AM and Hammer GD
      Editors: DeVita, Jr. VT, Lawrence TS, and Rosenberg SA.
      Edition 10th,2014
    • Genetic Steroid Disorders  

      Editors: New ML, Lekarev O, Parsa O, Yuen, TT, O'Malley B, and Hammer GD.ELSEVIER
      2013

    Abstracts/Posters

    • International Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Linsitinib (OSI-906, L) in Patients (pts) with Locally Advanced or Metastatic Adrenocortic... Fassnacht M, Baudin E, Berruti A, Demeure MJ, Fleege T, Poondru S, Quinn DI, Rorig R, Hammer GD, The Endocrine Society Annual Meeting Abstracts, 1/1/2014
    • Sonic Hedgehog in Adrenal Regeneration Finco I, and Hammer GD, The Endocrine Society Annual Meeting Abstracts, 1/1/2014
    • Multiple Mechanisms of Wnt/Betacat-Mediated Inhibition of Adrenocortical Steroidogenesis Walczak EM, Finco I, Bohin N, Kuick R, & Hammer GD, The Endocrine Society Annual Meeting Abstracts, 1/1/2014

    Lectures

    • Lecturer, Cell and Developmental Biology 582: Organogenesis: Stem Cells to Regenerative Biology (Adrenal Module) UMICH School of Medicine - 1/1/2015
    • Current Therapies for Adrenal Cancer 1/1/2014
    • Lecturer, Honors 252, Creativity in the Sciences and Arts (Adrenal Cancer) UMICH LSA - 1/1/2014

    Other

    Grant Support

    • Wnt-Responsive Adrenocortical Cells In Organ Maintenance And CancerNational Cancer Institute
      2010 - 2012
    • Mechanisms Of Adrenal DifferentiationNational Institute Of Diabetes And Digestive And Kidney Diseases
      2004 - 2012
    • Mechanisms Of Adrenal Cortex Growth/DifferentiationNational Institute Of Diabetes And Digestive And Kidney Diseases
      2000 - 2000
    • Orphan Nuclear Receptors In Development And DiseaseNational Institute Of Diabetes And Digestive And Kidney Diseases
      1999 - 2000
    • Orphan Nuclear Receptors In Development And DiseaseNational Institute Of Diabetes And Digestive And Kidney Diseases
      1996 - 1999

    Insurance Accepted

    • Aetna Choice POS II
    • Aetna HMO
    • BCBS Blue Card PPO
    • BCBS Illinois PPO
    • CIGNA HMO
    • CIGNA Open Access
    • CIGNA PPO
    • Cofinity PPO
    • First Health PPO
    • GHI PPO
    • HIP of New York - Select PPO
    • Horizon BCBS Direct Access
    • Horizon BCBS HMO
    • Horizon BCBS POS
    • Horizon BCBS PPO
    • Humana ChoiceCare Network PPO
    • Multiplan PHCS PPO
    • Multiplan PPO
    • Oxford Health Freedom
    • Oxford Health Liberty
    • QualCare HMO
    • QualCare PPO
    • United Healthcare - Direct Choice Plus POS
    • United Healthcare - Direct Options PPO
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