NdukaMgbechinyereAmankulorMD

PubMed

• An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma.
  Plute, T., Felker, J. T., Stephanie M Casillo, Taylor A Gatesman, Akanksha Chilukuri, Srinidhi Varadharajan, Brenden J Johnson, Daniel R David Premkumar, Esther P Jane...> ;Cell Reports. 2024 Jan 23
• 2 citations
  Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.
  Mark W Youngblood, Zeynep Erson-Omay, Chang Li, Hinda Najem, Süleyman Coșkun, Evgeniya Tyrtova, Julio D Montejo, Danielle F Miyagishima, Tanyeri Barak, Sayoko Nishimur...> ;Nature Communications. 2023 Oct 7
• A novel ARIH1::BRAF fusion in a glioma.
  Emily Xu, Yiming Zhong, Netta Golenberg, Liming Qiu, Zied Abdullaev, Kenneth Aldape, Linda Bagley, Casey H Halpern, Nduka Amankulor, MacLean P Nasrallah, Stone, S.> ;Journal of Neuropathology and Experimental Neurology. 2023 Oct 20
• Dissecting the tumor microenvironment of epigenetically driven gliomas: Opportunities for single-cell and spatial multiomics.
  Jonathan H Sussman, Jason Xu, Nduka Amankulor, Kai Tan> ;Neuro-Oncology Advances. 2023 Aug 21
• 2 citations
  Genetically modified IL2 bone-marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironment.
  Alessandro Canella, Matthew Nazzaro, Sakthi Rajendran, Claire Schmitt, Abigail Haffey, Giovanni Nigita, Diana Thomas, Justin M Lyberger, Gregory K Behbehani, Nduka M A...> ;Cell Reports. 2023 Aug 29
• Outcomes and Treatment Algorithm in Glioblastoma Patients 80 Years and Older.
  David Fogg, Zachary C Gersey, Matthew Pease, Arka N Mallela, Edward Andrews, Tritan Plute, Thomas M Pearce, Confidence Njoku-Austin, Austin Anthony, Nduka M Amankulor,...> ;World Neurosurgery. 2023 Oct 1
• 18 citations
  PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy.
  Duo Zhang, Albert M Li, Guanghui Hu, Menggui Huang, Fan Yang, Lin Zhang, Kathryn E Wellen, Xiaowei Xu, Crystal S Conn, Wei Zou, Mark Kahn, Seth D Rhoades, Aalim M Welj...> ;Cell Metabolism. 2023 Mar 7
• 5 citations
  Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain Metastases.
  James S Wilmott, Hussein Tawbi, Johnathan A Engh, Nduka M Amankulor, Brindha Shivalingam, Hiya Banerjee, Ismael A Vergara, Hansol Lee, Peter A Johansson, Peter M Fergu...> ;Clinical Cancer Research. 2023 Feb 1
• TP53-PTEN-NF1 depletion in human brain organoids produces a glioma phenotype.
  Sanjay K Singh, Yan Wang, Ahmed Habib, Mamindla Priyadarshini, Chowdari V Kodavali, Apeng Chen, Wencai Ma, Jing Wang, N U Farrukh Hameed, Baoli Hu, Gregory N Fuller, S...> ;Frontiers in Oncology. 2023 Jan 1
• 6 citations
  Distinguishing Progression from Pseudoprogression in Glioblastoma UsingF-Fluciclovine PET.
  Ali Nabavizadeh, Stephen J Bagley, Robert K Doot, Jeffrey B Ware, Anthony J Young, Satyam Ghodasara, Chao Zhao, Hannah Anderson, Erin Schubert, Erica L Carpenter, Jaco...> ;Journal of Nuclear Medicine. 2023 Jun 1
• 1 citations
  Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
  Golbourn, B., Halbert, M., Halligan, K., Varadharajan, S., Krug, B., Mbah, N., Kabir, N., Stanton, A., Locke, A., Casillo, S., Zhao, Y., Sanders, L., Cheney, A., Mulle...> ;Nature Cancer. 2022 Jul 1
• 3 citations
  Machine Learning Identification of Immunotherapy Targets in Low-Grade Glioma Using RNA Sequencing Expression Data.
  Prateek Agarwal, Oliver M Beale, Xiaoran Zhang, Poorva Sandlesh, Emade Jaman, Nduka Amankulor> ;World Neurosurgery. 2022 Jul 1
• 3 citations
  Targeting the translational machinery in gastrointestinal stromal tumors (GIST): a new therapeutic vulnerability.
  Donna M Lee, Angela Sun, Sneha S Patil, Lijun Liu, Aparna V Rao, Parker T Trent, Areej A Ali, Catherine Liu, Jessica L Rausch, Laura D Presutti, Adam Kaczorowski, Feli...> ;Scientific Reports. 2022 May 18
• 5 citations
  Risk of intracranial hemorrhage with direct oral anticoagulants vs low molecular weight heparin in glioblastoma: A retrospective cohort study.
  Lauren Reed-Guy, Arati S Desai, Richard E Phillips, Desiree Croteau, Karen Albright, Meghan O'Neill, Steven Brem, Donald M O'Rourke, Nduka M Amankulor, Stephen J Bagley> ;Neuro-Oncology. 2022 Dec 1
• 5 citations
  A Novel 5-Aminolevulinic Acid-Enabled Surgical Loupe System-A Consecutive Brain Tumor Series of 11 Cases.
  Xiaoran Zhang, Emade Jaman, Ahmed Habib, Alp Ozpinar, Edward Andrews, Nduka M Amankulor, Pascal O Zinn> ;Operative Neurosurgery. 2022 May 1
• 14 citations
  Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
  Felker, J. T., Brian J Golbourn, Matthew E Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E Mbah, Nisha Kabir, Ann-Catherine J Stanton, Abigail ...> ;Nature Cancer. 2022 May 1
• 1 citations
  Matched analysis of patient gender and meningioma resection outcomes.
  Susanna D Howard, Svetlana Kvint, Austin J Borja, Ryan Dimentberg, Kaitlyn Shultz, Nduka M Amankulor, Scott D McClintock, Neil R Malhotra> ;British Journal of Neurosurgery. 2022 Oct 1
• 2 citations
  In vivo efficacy of decitabine as a natural killer cell-mediated immunotherapy against isocitrate dehydrogenase mutant gliomas.
  Xiaoran Zhang, Wi Jin Kim, Aparna V Rao, Emade Jaman, Christopher P Deibert, Poorva Sandlesh, Katharine Krueger, Jordan C Allen, Nduka M Amankulor> ;Neurosurgical Focus. 2022 Feb 1
• 11 citations
  The Subventricular Zone in Glioblastoma: Genesis, Maintenance, and Modeling.
  Jamison Beiriger, Ahmed Habib, Nicolina Jovanovich, Chowdari V Kodavali, Lincoln Edwards, Nduka Amankulor, Pascal O Zinn> ;Frontiers in Oncology. 2022 Jan 1
• Percutaneous fixation for the treatment of metastatic spinal disease provides effective symptom palliation with low rates of hardware failure.
  Emade Jaman, Xiaoran Zhang, Jordan Allen, Raj G Saraiya, Savannah Tollefson, D Kojo Hamilton, Nduka M Amankulor> ;Surgical Neurology International. 2022 Jan 1
• A liquid fraction of extracellular matrix inhibits glioma cell viabilityand.
  Mark H Murdock, George S Hussey, Jordan T Chang, Ryan C Hill, David G Nascari, Aparna V Rao, Kirk C Hansen, Lesley M Foley, T Kevin Hitchens, Nduka M Amankulor, Stephe...> ;Oncotarget. 2022 Jan 1
• 6 citations
  The dominant TP53 hotspot mutation in-mutant astrocytoma, R273C, has distinctive pathologic features and sex-specific prognostic implications.
  Daniel F Marker, Sameer Agnihotri, Nduka Amankulor, Geoffrey H Murdoch, Thomas M Pearce> ;Neuro-Oncology Advances. 2021 Dec 11
• 2 citations
  The Evolving Role of Induced Pluripotent Stem Cells and Cerebral Organoids in Treating and Modeling Neurosurgical Diseases.
  Nicolina Jovanovich, Ahmed Habib, Chowdari Kodavali, Lincoln Edwards, Nduka Amankulor, Pascal O. Zinn> ;World Neurosurgery. 2021 Nov 1
• 2 citations
  History of atopy confers improved outcomes in IDH mutant and wildtype lower grade gliomas.
  Emade Jaman, Xiaoran Zhang, Poorva Sandlesh, Ahmed Habib, Jordan Allen, Raj G. Saraiya, Nduka M. Amankulor, Pascal O. Zinn> ;Journal of Neuro-Oncology. 2021 Oct 29
• 1 citations
  Headlight and loupe-based fluorescein detection system in brain tumor surgery; a firstin-human experience.
  Xiaoran Zhang, Ahmed Habib, Emade Jaman, Arka N. Mallela, Nduka Amankulor, Pascal O. Zinn> ;Journal of Neurosurgical Sciences. 2021 Oct 14
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Journal Articles

• Single-Cell Profiling of Human Gliomas Reveals Macrophage Ontogeny as a Basis for Regional Differences in Macrophage Activation in the Tumor Microenvironment  
  Daniel A Lim, S John Liu, Manish Aghi, Hideho Okada, Nduka M Amankulor, Arnold R Kriegstein, BioMed Central