CharlesDavidAdairMDMBA

Obstetrics & Gynecology • Chattanooga, TN

Critical Care Medicine, Maternal & Fetal Medicine/High Risk, Clinical Pharmacology

Managing Director and Co-Founder of Solas BioVentures Professor Emeritus and retired Professor, vice chairman university of Tennessee college of medicine, department of OB/GYN

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Office
412 Georgia Ave suite 201
Chattanooga, TN 37403
Phone+1 423-309-5713
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Education & Training

Wake Forest University School of MedicineFellowship, Maternal-Fetal Medicine, 1994 - 1996
University of Florida College of Medicine JacksonvilleResidency, Obstetrics and Gynecology, 1990 - 1994
Marshall University Joan C. Edwards School of MedicineClass of 1990

Certifications & Licensure

GA State Medical License 1998 - 2025
VA State Medical License 1994 - 2024
NC State Medical License 1994 - 2024
TN State Medical License 1997 - 2024
KY State Medical License 2021 - 2023
SC State Medical License 2016 - 2021
AL State Medical License 2018 - 2020
LA State Medical License 1996 - 2000
FL State Medical License 1991 - 1998
American Board of Obstetrics and Gynecology Obstetrics & Gynecology
American Board of Obstetrics and Gynecology Maternal-Fetal Medicine
American Society HypertensionHypertension Specialist
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Awards, Honors, & Recognition

Fellow (FACOG) American Congress of Obstetricians and Gynecologists

Clinical Trials

Appendectomy Versus no Appendectomy With Cesarean Section Start of enrollment: 2002 Jul 01
Completed
Not Applicable

Publications & Presentations

PubMed

1 citations
Methods for the induction of labor: efficacy and safety.
Luis Sanchez-Ramos, Lisa D Levine, Anthony C Sciscione, Ellen L Mozurkewich, Patrick S Ramsey, Charles David Adair, Andrew M Kaunitz, Jordan A McKinney> ;American Journal of Obstetrics and Gynecology. 2024 Mar 1
2 citations
Silencing of Fli1 Gene Mimics Effects of Preeclampsia and Induces Collagen Synthesis in Human Umbilical Arteries.
Natalia I Agalakova, Vitaly A Reznik, Ivan A Ershov, Ekaterina A Lupanova, Olga V Nadei, Dmitry O Ivanov, C David Adair, Alexei Y Bagrov> ;American Journal of Hypertension. 2022 Sep 1
3 citations
Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia.
Natalia I Agalakova, Yulia N Grigorova, Ivan A Ershov, Vitaly A Reznik, Elena V Mikhailova, Olga V Nadei, Leticia Samuilovskaya, Larisa A Romanova, C David Adair, Irin...> ;International Journal of Molecular Sciences. 2022 Mar 19
6 citations
Preeclampsia: Cardiotonic Steroids, Fibrosis, Fli1 and Hint to Carcinogenesis
Natalia I. Agalakova, Nikolai I. Kolodkin, C. David Adair, Alexander P. Trashkov, Alexei Y. Bagrov> ;International Journal of Molecular Sciences. 2021 Feb 16
5 citations
Antibody against Na/K-ATPase Inhibitor Lowers Blood Pressure and Increases Vascular Fli1 in Experimental Preeclampsia
Natalia I. Agalakova, Vitaly A. Reznik, Olga V Nadei, Ivan A. Ershov, Olga S Rassokha, Marina L. Vasyutina, Dmitry O. Ivanov, C. David Adair, Michael M. Galagudza, Ale...> ;American Journal of Hypertension. 2020 May 21
5 citations
Endogenous Bufadienolides, Fibrosis and Preeclampsia
Vitaliy A Reznik, Vladimir A. Kashkin, Natalia I. Agalakova, C. David Adair, Alexei Y. Bagrov> ;Cardiology Research and Practice. 2019 Dec 12
35 citations
Placental concentrations of essential, toxic, and understudied metals and relationships with birth outcomes in Chattanooga, TN.
C. Mikelson, Jacopo Troisi, Amy LaLonde, Steven J. K. Symes, Sally W. Thurston, Lauren M. DiRe, C. David Adair, Richard K. Miller, Sean Richards> ;Environmental Research. 2019 Jan 1
13 citations
Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia.
Olga V. Fedorova, Valentina V. Ishkaraeva, Yulia Grigorova, Vitaly A. Reznik, Nikolai I. Kolodkin, Irina E. Zazerskaya, Valentina Zernetkina, Natalia I. Agalakova, Nat...> ;International Journal of Molecular Sciences. 2018 Aug 13
7 citations
Robotic-Assisted Laparoscopic Abdominal Cerclage Placement During Pregnancy
S. Kyle Gonzales, C. David Adair, Carlos Torres, Eliezer D. Rodriguez, S Mohling, Rayan Elkattah, Stephen DePasquale> ;Journal of Minimally Invasive Gynecology. 2017 Dec 1
3 citations
Assessment of a cervicometer compared to transvaginal ultrasound in identifying women with a short cervical length: a multicenter study
Jason K. Baxter, C. David Adair, Michael J. Paidas, Matthew K. Hoffman, Frances J. Kivel, Deb Cebrik, Michael G. Ross> ;American Journal of Obstetrics and Gynecology. 2016 Aug 1
17 citations
Removal versus retention of cerclage in preterm premature rupture of membranes: a randomized controlled trial
Anna M Galyean, Thomas J. Garite, Kimberly Maurel, Diana Abril, Charles Adair, Paul Browne, C. Andrew Combs, Helen How, Brian Iriye, Michelle A. Kominiarek, George Lu,...> ;American Journal of Obstetrics and Gynecology. 2014 Oct 1
19 citations
Expectant management of mild preeclampsia versus superimposed preeclampsia up to 37 weeks
Amy M. Valent, Emily DeFranco, Allessa Allison, Ahmed Salem, Lori Klarquist, Kyle Gonzales, Mounira Habli, C. David Adair, Casey Armistead, Yuping Wang, David F. Lewis...> ;American Journal of Obstetrics and Gynecology. 2015 Apr 1
34 citations
Initial experience with a dual-balloon catheter for the management of postpartum hemorrhage
Gary A. Dildy, Michael A. Belfort, C. David Adair, Kimberly Destefano, Donna Robinson, Garrett Lam, Thomas H. Strong, Clive Polon, Robert Massaro, Jayasri Bukkapatnam,...> ;American Journal of Obstetrics and Gynecology. 2014 Feb 1
3 citations
Magnesium Sulfate Potentiates Effect of Digifab on Marinobufagenin-Induced Na/K-ATPase Inhibition
Irina E. Zazerskaya, Valentina V. Ishkaraeva, Elena V. Frolova, Nelly G. Solodovnikova, Yulia Grigorova, C. David Adair, Olga V. Fedorova, Alexei Y. Bagrov> ;American Journal of Hypertension. 2013 Nov 1
19 citations
Digoxin antibody fragment, antigen binding (Fab), treatment of preeclampsia in women with endogenous digitalis-like factor: a secondary analysis of the DEEP Trial.
Garrett K. Lam, Moana Hopoate-Sitake, C. David Adair, Vardaman M. Buckalew, Donna D. Johnson, David F. Lewis, Christopher J. Robinson, George R. Saade, Steven W. Graves> ;American Journal of Obstetrics and Gynecology. 2013 Aug 1
411 citations
Non-Invasive Chromosomal Evaluation (NICE) Study: results of a multicenter prospective cohort study for detection of fetal trisomy 21 and trisomy 18
Mary E. Norton, Herb Brar, Jonathan D. Weiss, Ardeshir Karimi, Louise C. Laurent, Aaron B. Caughey, M. Hellen Rodriguez, John Williams, Michael E. Mitchell, Charles D....> ;American Journal of Obstetrics and Gynecology. 2012 Aug 1
13 citations
DigiFab interacts with endogenous cardiotonic steroids and reverses preeclampsia-induced Na/K-ATPase inhibition.
Valentina V. Ishkaraeva-Yakovleva, Olga V. Fedorova, Nelly G. Solodovnikova, Elena V. Frolova, Anton Bzhelyansky, I. Emelyanov, C. David Adair, Irina E. Zazerskaya, Al...> ;Reproductive Sciences. 2012 May 30
7 citations
Increasing evidence for and regulation of a human placental endogenous digitalis-like factor.
Jie Ma, M. Sean Esplin, C. David Adair, Lorrie A. Mason, Steven W. Graves> ;Reproductive Sciences. 2012 Feb 16
3 citations
Digoxin immune fab protects endothelial cells from ouabain-induced barrier injury.
Yuping Wang, Ruping Fan, Yang Gu, C. David Adair> ;American Journal of Reproductive Immunology. 2012 Jan 1
3 citations
Environmental toxicant exposure during pregnancy.
Rebecca T. Red, Sean M. Richards, Carlos Torres, C. David Adair> ;Obstetrical & Gynecological Survey. 2011 Mar 1
7 citations
Digibind Reverses Inhibition of Cellular Rb+ Uptake Caused by Endogenous Sodium Pump Inhibitors Present in Serum and Placenta of Women with Preeclampsia:
Moana Hopoate-Sitake, C. David Adair, Lorrie A. Mason, Carlos Torres, Joseph Kipikasa, Steven W. Graves> ;Reproductive Sciences. 2011 Feb 1
26 citations
Digoxin immune fab treatment for severe preeclampsia.
C. David Adair, Vardaman M. Buckalew, Steven W. Graves, Garrett K. Lam, Donna D. Johnson, George R. Saade, David F. Lewis, Christopher J. Robinson, Theodore M. Danoff,...> ;American Journal of Perinatology. 2010 Aug 18
49 citations
Labor induction with intravaginal misoprostol compared with the dinoprostone vaginal insert: a systematic review and metaanalysis
S. Campbell Austin, Luis Sanchez-Ramos, C. David Adair> ;American Journal of Obstetrics and Gynecology. 2010 Jun 1
60 citations
Effect of progesterone on cervical shortening in women at risk for preterm birth: secondary analysis from a multinational, randomized, double-blind, placebo-controlled...
John M. O'Brien, Emily DeFranco, Charles Adair, D. F. Lewis, David Hall, Helen How, M. Bsharat, George W. Creasy> ;Ultrasound in Obstetrics & Gynecology. 2009 Dec 1
5 citations
Digibind attenuates cytokine TNFα-induced endothelial inflammatory response: potential benefit role of Digibind in preeclampsia
Yuping Wang, David F. Lewis, Charles Adair, Yang Gu, Lorrie A. Mason, Joseph Kipikasa> ;Journal of Perinatology. 2009 Mar 1
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