PeterEFecciMDPhD

PubMed

• Dose-Incorporated Deep Ensemble Learning for Improving Brain Metastasis SRS Outcome Prediction.
  Jingtong Zhao, Yuqi Wang, Zhenyu Yang, Yunfeng Cui, Zachary J Reitman, Kyle Lafata, John Kirkpatrick, Fang-Fang Yin, Scott Floyd, Chunhao Wang, Eugene Vaios, Peter Fecci> ;International Journal of Radiation Oncology, Biology, Physics. 2024 Apr 12
• Laser interstitial thermal therapy for new and recurrent meningioma: a prospective and retrospective case series.
  Veronica L Chiang, Sangami Pugazenthi, William A Leidig, Analiz Rodriguez, Sujit Prabhu, Aden P Haskell-Mendoza, Peter E Fecci, Dimitris G Placantonakis, Steven R Abra...> ;Journal of Neurosurgery. 2024 Mar 8
• Incidence and imaging characteristics of difficult to detect retrospectively identified brain metastases in patients receiving repeat courses of stereotactic radiosurg...
  Andrew Fairchild, Joseph K Salama, Devon Godfrey, Walter F Wiggins, Bradley G Ackerson, Taofik Oyekunle, Donna Niedzwiecki, Peter E Fecci, John P Kirkpatrick, Scott R ...> ;Journal of Neuro-Oncology. 2024 Mar 1
• Automated Segmentation of Ablated Lesions Using Deep Convolutional Neural Networks: A Basis for Response Assessment Following Laser Interstitial Thermal Therapy.
  Haskell-Mendoza, A., Reason, E., Gonzalez, A., Jackson, J., Srinivasan, E., Herndon, J., Calabrese, E., Sankey, E., Fecci, P.> ;Neuro-Oncology. 2024 Jan 3
• Utility of Routine Preoperative Urinalysis in the Prevention of Surgical Site Infections.
  Aden P Haskell-Mendoza, Senthil Radhakrishnan, Ana Lisa Nardin, Kristina Eilbacher, Lexie Zidanyue Yang, Joshua D Jackson, Hui-Jie Lee, John H Sampson, Peter E Fecci> ;World Neurosurgery. 2023 Dec 1
• 10 citations
  CD8T cells maintain killing of MHC-I-negative tumor cells through the NKG2D-NKG2DL axis.
  Emily C Lerner, Karolina I Woroniecka, Vincent M D'Anniballe, Daniel S Wilkinson, Aditya A Mohan, Selena J Lorrey, Jessica Waibl-Polania, Lucas P Wachsmuth, Alexandra ...> ;Nature Cancer. 2023 Sep 1
• 6 citations
  Correcting the drug development paradigm for glioblastoma requires serial tissue sampling.
  Kirit Singh, Kelly M Hotchkiss, Ian F Parney, John De Groot, Solmaz Sahebjam, Nader Sanai, Michael Platten, Evanthia Galanis, Michael Lim, Patrick Y Wen, Giuseppe Minn...> ;Nature Medicine. 2023 Oct 1
• Gold Nanostars Obviate Limitations to Laser Interstitial Thermal Therapy (LITT) for the Treatment of Intracranial Tumors.
  Ethan S Srinivasan, Yang Liu, Ren A Odion, Pakawat Chongsathidkiet, Lucas P Wachsmuth, Aden P Haskell-Mendoza, Ryan M Edwards, Aidan J Canning, Gavin Willoughby, Josep...> ;Clinical Cancer Research. 2023 Aug 15
• 1 citations
  Systemic immune derangements are shared across various CNS pathologies and reflect novel mechanisms of immune privilege.
  Selena J Lorrey, Jessica Waibl Polania, Lucas P Wachsmuth, Alexandra Hoyt-Miggelbrink, Zachariah P Tritz, Ryan Edwards, Delaney M Wolf, Aaron J Johnson, Peter E Fecci,...> ;Neuro-Oncology Advances. 2023 Apr 11
• 4 citations
  Efficacy of laser interstitial thermal therapy for biopsy-proven radiation necrosis in radiographically recurrent brain metastases.
  Michael Chan, Steven Tatter, Veronica Chiang, Peter Fecci, Roy Strowd, Sujit Prabhu, Constantinos Hadjipanayis, John Kirkpatrick, David Sun, Kaylyn Sinicrope, Alireza ...> ;Neuro-Oncology Advances. 2023 Mar 28
• 1 citations
  Erratum to "E.C. Lerner, E.S. Srinivasan, G. Broadwater, et al. Factors Associated With New-Onset Seizures Following Stereotactic Radiosurgery for Newly Diagnosed Brai...
  Emily Claire Lerner, Ethan S Srinivasan, Gloria Broadwater, Aden P Haskell-Mendoza, Eugene J Vaios, Ryan M Edwards, Lucas P Wachsmuth, David Huie, Scott R Floyd, Justu...> ;Advances in Radiation Oncology. 2023 Mar 14
• 1 citations
  Risk of Tract Seeding Following Laser Interstitial Thermal Therapy for Brain Tumors.
  Aden P Haskell-Mendoza, Ethan S Srinivasan, Emily C Lerner, Ryan M Edwards, Allison M Schwalb, Joshua D Jackson, Andrew A Hardigan, Eugene J Vaios, Peter E Fecci> ;Neurosurgery. 2023 Jul 1
• 4 citations
  Racial disparities in inpatient clinical presentation, treatment, and outcomes in brain metastasis.
  Edwin McCray, Romaric Waguia, Rafael de la Garza Ramos, Meghan J Price, Theresa Williamson, Tara Dalton, Daniel M Sciubba, Reza Yassari, Andrea N Goodwin, Peter Fecci,...> ;Neuro-Oncology Practice. 2023 Feb 1
• Laser ablation of a sphenoid wing meningioma: A case report and review of the literature.
  Aden P Haskell-Mendoza, Ethan S Srinivasan, Alexander D Suarez, Peter E Fecci> ;Surgical Neurology International. 2023 Jan 1
• Preoperative validation of edema-corrected tractography in neurosurgical practice: translating surgeon insights into novel software implementation.
  Hodges, W., Adamyan, H., Hayes, T., Verma, R., Baboyan, V., Koga, S., Fecci, P., Tsvankin, V., Pradilla, G., Hoang, K., Lee, I., Sankey, E., Codd, P., Huie, D., Zachar...> ;Frontiers in Neurology. 2023 Jan 1
• 2 citations
  Outcomes in Patients with Intact and Resected Brain Metastasis Treated with 5-Fraction Stereotactic Radiosurgery.
  David J Carpenter, Andrew T Fairchild, Justus D Adamson, Peter E Fecci, John H Sampson, James E Herndon, Jordan A Torok, Trey C Mullikin, Grace J Kim, Zachary J Reitma...> ;Advances in Radiation Oncology. 2022 Dec 29
• Commentary: Laser Interstitial Thermal Therapy for First-Line Treatment of Surgically Accessible Recurrent Glioblastoma: Outcomes Compared With a Surgical Cohort.
  Allison M Schwalb, Ethan S Srinivasan, Peter E Fecci> ;Neurosurgery. 2022 Dec 1
• 8 citations
  Neuronal CaMKK2 promotes immunosuppression and checkpoint blockade resistance in glioblastoma.
  William H Tomaszewski, Jessica Waibl-Polania, Molly Chakraborty, Jonathan Perera, Jeremy Ratiu, Alexandra Miggelbrink, Donald P McDonnell, Mustafa Khasraw, David M Ash...> ;Nature Communications. 2022 Oct 29
• Prognostic Model for Intracranial Progression after Stereotactic Radiosurgery: A Multicenter Validation Study.
  David J Carpenter, Brahma Natarajan, Muzamil Arshad, Divya Natesan, Olivia Schultz, Michael J Moravan, Charlotte Read, Kyle J Lafata, Will Giles, Peter Fecci, Trey C M...> ;Cancers. 2022 Oct 22
• 2 citations
  A Deep Learning-Based Computer Aided Detection (CAD) System for Difficult-to-Detect Brain Metastases.
  Andrew T Fairchild, Joseph K Salama, Walter F Wiggins, Peter E Fecci, John P Kirkpatrick, Scott R Floyd, Devon J Godfrey, Ackerson, B.> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Mar 1
• 2 citations
  Factors Associated With New-Onset Seizures Following Stereotactic Radiosurgery for Newly Diagnosed Brain Metastases.
  Emily C Lerner, Ethan S Srinivasan, Gloria Broadwater, Aden P Haskell-Mendoza, Ryan M Edwards, David Huie, Eugene J Vaios, Scott R Floyd, Justus D Adamson, Peter E Fecci> ;Advances in Radiation Oncology. 2022 Aug 27
• 3 citations
  Combination laser interstitial thermal therapy plus stereotactic radiotherapy increases time to progression for biopsy-proven recurrent brain metastases.
  Matthew M Grabowski, Ethan S Srinivasan, Eugene J Vaios, Eric W Sankey, Balint Otvos, Daria Krivosheya, Alex Scott, Michael Olufawo, Jun Ma, Elena I Fomchenko, James E...> ;Neuro-Oncology Advances. 2022 Jun 2
• 12 citations
  Time to Steroid Independence After Laser Interstitial Thermal Therapy vs Medical Management for Treatment of Biopsy-Proven Radiation Necrosis Secondary to Stereotactic...
  Eric W Sankey, Matthew M Grabowski, Ethan S Srinivasan, Andrew S Griffin, Elizabeth P Howell, Balint Otvos, Vadim Tsvankin, Gene H Barnett, Alireza M Mohammadi, Peter ...> ;Neurosurgery. 2022 Jun 1
• 15 citations
  Laser ablation: Heating up the anti-tumor response in the intracranial compartment.
  Emily C Lerner, Ryan M Edwards, Daniel S Wilkinson, Peter E Fecci> ;Advanced Drug Delivery Reviews. 2022 Jun 1
• 19 citations
  Efficacy of laser interstitial thermal therapy (LITT) for newly diagnosed and recurrentwild-type glioblastoma.
  John F de Groot, Albert H Kim, Sujit Prabhu, Ganesh Rao, Adrian W Laxton, Peter E Fecci, Barbara J O'Brien, Andrew Sloan, Veronica Chiang, Stephen B Tatter, Alireza M ...> ;Neuro-Oncology Advances. 2022 Apr 6
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Journal Articles

• Upfront Magnetic Resonance Imaging-Guided Stereotactic Laser-Ablation in Newly Diagnosed Glioblastoma: A Multicenter Review of Survival Outcomes Compared to a Matched ...  
  Cosette Dechant, Gene H Barnett, Andreas Seas, Eric C Leuthardt, Kevin O Juarez, Hanna Kemeny, Peter E Fecci, Manmeet S Ahluwalia, Mayur Sharma, Thomas L Beaumont, Alb..., Neurosurgery
• Sequestration of T Cells in Bone Marrow in the Setting of Glioblastoma and Other Intracranial Tumors  
  Peter E Fecci, Cosette A Dechant, Robert L Martuza, Karolina Woroniecka, Brian V Nahed, James E Herndon, William T Curry, Aladine A Elsamadicy, John H Sampson, Michael..., Nature
• Antibody-based immunotherapy for malignant glioma  
  Gedeon PC, Riccione KA, Fecci PE, Sampson JH, Semin Oncol, 7/1/2014
• Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung cancers  
  Akbay EA, Koyama S, Carretaro J, Altabef A, Tchaicha JH, Christensen CL, Mikse OR, Butaney M, Cherniack AD, Beauchamp EM, Pugh TJ, Reibel JB, Cohoon TJ, F..., Cancer Discovery, 12/1/2013
• Multifaceted Oncolytic Virus Therapy For Glioblastoma In An Immune-Competent Cancer Stem Cell Model  
  Cheema TA, Wakimoto H, Fecci PE, Kuroda T, Jeyaretna DS, Martuza RL, Rabkin SD, Proc Nat Acad Sci USA, 7/16/2013
• An Update of Vaccine Therapy and Other Immunotherapeutic Approaches for GBM  
  Reardon DA, Wucherpfennig KW, Freeman G, Wu C, Chiocca EA, Wen PY, Curry WT, Mitchell DA, Fecci PE, Sampson JH, Dranoff G, Expert Rev Vacc, 6/1/2013
• Regulatory T-cells move in when gliomas say “I-DO”  
  Choi BD, Fecci P, Sampson JH, Clin Cancer Res, 10/1/2012
• Sequential Immunotherapy by Vaccination with GM-CSF Expressing Glioma Cells and CTLA-4 Blockade Effectively Treats Established Murine Intracranial Tumors  
  Agarwalla PK, Barnard Z, Fecci PE, Dranoff G, Curry WT, J Immunother, 6/1/2012
• Immunotherapy of malignant brain tumors  
  Mitchell DM, Fecci PE, Sampson JH, Immunological Rev, 4/1/2008
• Molecular strategies for the treatment of malignant glioma  
  Selznick LA, Shamji MF, Fecci P, Gromeier M, Friedman AH, Sampson JH, Neurosurg Rev, 4/1/2008
• Systemic blockade of CTLA-4 ameliorates glioma-induced changes to the CD4 T-cell compartment without affecting regulatory T-cell function  
  Fecci PE, Ochiai H, Grossi PM, Sweeney AE, Archer GE, Chewning TA, Mitchell DA, Dranoff G, Allison JP, Bigner DD, and Sampson JH, Clin Cancer Res, 4/1/2007
• Expression profiling of CD4+, CD8+ and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals immunosuppression of the transcriptome  
  Learn CL, Fecci PE, Schmittling RJ, Xie W, Karikari I, Mitchell DA, Archer GE, Wei Z, Dressman H, Sampson JH, Clin Cancer Res, 12/1/2006
• Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T-cells  
  Fecci PE, Sweeney AE, Grossi PM, Nair S, Learn CA, Mitchell DA, Cui X, Cummings TM, Bigner DD, and Sampson JH, Clin Cancer Res, 7/1/2006
• The history, evolution, and clinical use of dendritic cell-based immunization strategies for the therapy of brain tumors  
  Fecci PE, Mitchell DA, Archer GE, Morse MA, Lyerly HK, Bigner DD, Sampson JH, J Neurooncol, 8/1/2003
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Books/Book Chapters

• Glioblastoma Multiforme 
  Chapter: Chapter 13: Adoptive immunotherapy for treatment of glioblastoma. 
  Mitchell DA, Fecci PE, Sampson JHEditors: Markert J, DeVita VT, Rosenberg SA.Jones and Bartlett Publishers, Sudbury, MA2005

Lectures

• Lost and Found: The Bone Marrow as Harbor for Lost T-cells in Patients and Mice with Glioblastoma 
  Cornell University / Weill Medical College, New York, NY - 1/1/2014
• Lost and Found: The Bone Marrow as Harbor for Lost T-cells in Patients and Mice with Glioblastoma, Invited Lecture 
  Duke University, Durham, NC - 1/1/2014
• Lost and Found: Therapeutic Implications of Bone Marrow as Harbor for Lost T-cells in Glioma, Invited Oral Presentation 
  Brewster, MA - 1/1/2013
• Of Mice and Men: Matched Observations of Lymphopenia, Splenic Retraction, and the Bone Marrow as Harbor for Lost T-cells in Mice and Patients with Glioblastoma, Inv... 
  Brewster, MA - 1/1/2013
• Lost and Found II: The Bone Marrow as Harbor for Lost T-cells in Patients and Mice with Glioblastoma 
  Massachusetts General Hospital, Boston, MA - 1/1/2013
• Lost and Found: Therapeutic Implications of Bone Marrow as Harbor for Lost T-cells in Glioma 
  Massachusetts General Hospital, Boston, MA - 1/1/2013
• Lost and Found: Systemic Immune Dysregulation and the Bone Marrow as Harbor for Lost T-cells in Treatment-Naïve Patients and Mice with Glioblastoma, Invited Oral Pres... 
  Newport Beach, CA - 1/1/2013
• Malignant Brain Tumors: The Path to Intolerance 
  Dana Farber Cancer Institute, Boston, MA - 1/1/2012
• Fostering Intolerance: Preclinical modeling of CTLA-4 Blockade in Glioblastoma. Invited Oral Presentation 
  Washington, DC - 1/1/2012
• Glioblastoma: Ushering in a New Standard of Care 
  Massachusetts General Hospital, Boston, MA - 1/1/2009
• The Role of Regulatory T-cells as Barriers to Cellular and Anti-tumor Immunity in Patients with Malignant Glioma, Keynote Address 
  Orlando, FL - 1/1/2006
• Partnering Regulatory T-cell Depletion with Radiotherapy 
  San Francisco, CA - 1/1/2006
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Other

• "Trimodal Cancer Therapy" A Method of Eliminating or Functionally Impairing Regulatory T-cells (Use of the IL-2 Receptor Alpha (CD25)-Blocking Monoclonal Antibody Dacl... 
  Fecci PE, US Application # 61/261, 476
  3/2/2006