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Office
Lab Office -- 55 Fruit Street
Gray-Jackson, Room 504
Boston, MA 02114Phone+1 617-643-6444Fax+1 617-643-6443- Is this information wrong?
Summary
- Jatin (Jay) M. Vyas is an Associate Professor in Medicine at the Harvard Medical School and the Massachusetts General Hospital in the Department of Medicine, Division of Infectious Diseases. He attended Baylor College of Medicine in their Medical Scientist Training Program where Jay received his Ph.D. in 1994 and MD in 1996. He completed his Ph.D. with Dr. Robert R. Rich in the area of Microbiology and Immunology. Upon completion of his MD in 1996, Jay moved to Boston to complete his medical internship and residency in internal medicine in the Department of Medicine at the Massachusetts General Hospital. He completed his fellowship in Infectious Diseases in the Massachusetts General Hospital/Brigham and Women’s Hospital program. He then served as the chief resident in medicine for 18 months. Following a period of extended post-doctoral research training in the Harvard Department of Pathology and Whitehead Institute for Biomedical Research with Dr. Hidde Ploegh, Dr. Vyas joined the faculty of the Harvard Medical School and the Massachusetts General Hospital in 2007. Dr. Vyas is internationally recognized for his work in fungal immunology, investigating how our body responds to fungal pathogens. Invasive fungal infections are a leading killer of patients with compromised immune systems. His laboratory is supported by NIH grants, industry collaborations and private philanthropy. He has been selected as an Infectious Disease Society of America Fellow. He was also elected to the American Society for Clinical Investigation. He has also been elected as a Fellow in the American College of Physicians. In 2014, Jatin was named the tenth Program Director of the MGH Department of Medicine Residency Program, supervising 207 interns and residents. As an NIH-funded investigator with interests in basic science, Dr. Vyas provides a unique perspective to the medical housestaff. He mentors physician-scientists who aspire to impact clinical medicine through investigation.
Education & Training
- Harvard Medical School and Whitehead Institute for Biomedical ResearchPost-Doctoral Fellowship, Laboratory of Hidde Ploegh, PhD, 2001 - 2007
- Massachusetts General Hospital/Brigham and Women's Hospital/Harvard Medical SchoolFellowship, Infectious Disease, 1999 - 2003
- Massachusetts General HospitalResidency, Internal Medicine, 1996 - 1999
- Baylor College of MedicineClass of 1996
- Baylor College of MedicinePhD, Microbiology and Immunology, 1989 - 1994
- Baylor College of MedicinePh.D., Microbiology and Immunology, 1989 - 1994
- University of Texas at AustinB.A., Liberal Arts Honors Program, with Special Honors, 1985 - 1989
Certifications & Licensure
- MA State Medical License 1998 - 2025
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Infectious Disease
Awards, Honors, & Recognition
- Chief Resident in Medicine Massachusetts General Hospital, 2000-2001
- Krane Award for Outstanding Basic Science, Department of Medicine Massachusetts General Hospital, 2015
- Partners in Excellence, Outstanding service by the PIBC Partners Healthcare, 2012
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Publications & Presentations
PubMed
- Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses.Vyas, J. M., Marta Brandt, Zhifang Cao, Chirag Krishna, Jennifer L Reedy, Xiebin Gu, Richard A Dutko, Blayne A Oliver, Betsabeh Khoramian Tusi, Jihye Park, Lauren Rich...> ;Cell Reports. 2024 Mar 26
- AbcA transporter enhances persister formation under β-lactam exposure.Vyas, J. M., Q C Truong-Bolduc, Y Wang, R Ferrer-Espada, J L Reedy, A T Martens, Y Goulev, J Paulsson, J M Vyas, D C Hooper> ;Antimicrobial Agents and Chemotherapy. 2024 Mar 6
- Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING.Vyas, J. M., Hannah Brown Harding, Geneva N Kwaku, Christopher M Reardon, Nida S Khan, Daniel Zamith-Miranda, Robert Zarnowski, Jenny M Tam, Collins K Bohaen, Lauren R...> ;Nature Microbiology. 2024 Jan 1
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Journal Articles
- Policy Recommendations for Optimizing the Infectious Diseases Physician-Scientist WorkforceWendy Armstrong, Ebbing Lautenbach, Kyle J Popovich, C Buddy Creech, Roger Bedimo, Upinder Singh, Jatin M Vyas, The Journal of Infectious Diseases
- The Great Opportunity: Cultivating Scientific Inquiry in Medical ResidencyMarc N Wein, Michael K Mansour, Jatin M Vyas, Jayaraj Rajagopal, Mark C Fishman, Kathleen E Corey, Caroline L Sokol, Katrina A Armstrong, The Journal of Infectious Diseases
- Case records of the Massachusetts General Hospital Case 5-2016 — A 43-Year-Old Man with Altered Mental Status and a History of Alcohol UseTerry AR, Kahle KT, Larvie M, Vyas JM, Stemmer-Rachamimov A, New England Journal of Medicine, 1/1/2016
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Books/Book Chapters
Lectures
- Approach to MeningitisMassachusetts General Hospital - 1/1/2016
- Approach to CNS infections1/1/2016
- Fun with Fungi: A Research Career Inspired by the Bigelow Medical Service.Massachusetts General Hospital - 1/1/2015
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Other
- Antibiotic susceptibility testing in specific clinical situations.Jatin M Vyas, MD, PhD Mary Jane Ferraro, PhD, MPH, UptoDate
Boston, MA - 1/1/2003 - Overview of antibacterial susceptibility testing.Jatin M Vyas, MD, PhD Mary Jane Ferraro, PhD, MPH, UptoDate
Boston, MA - 1/1/2003 - The peptide binding specificity of the MHC class I-b molecule, H-2M3a. Thesis.Vyas JM
Baylor College of Medicine, Houston, TX - 1/1/1994 - Join now to see all
Press Mentions
- FDA Advisers Offer a Vote of Confidence for Gene TherapiesJune 19th, 2022
- Addressing the Curiosity Decline in MedicineOctober 1st, 2019
- Optimal Learning Environments Discussed at WCM-Q Grand RoundsApril 10th, 2019
Grant Support
- Systems Analysis of Innate Immune Responses to Fungal-Derived CarbohydratesNational Institute of Allergy and Infectious Disease, NIH2015–2017
- The role of TLR9 on Aspergillus fumigatus phagosomesNational Institute of Allergy and Infectious Disease, NIH2013–2017
- Functional Role Of The Tetraspanin Cd82/Kai1 In Innate And Adaptive ImmunityNational Institute Of Allergy And Infectious Diseases2011
- Modulation Of Dendritic Cell Function By CytomegalovirusNational Institute Of Allergy And Infectious Diseases2004–2008
Professional Memberships
- Fellow
- Member
- Fellow
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