HrissanthiIkonomidouMD

PubMed

• MK-801 prevents hypobaric-ischemic neuronal degeneration in infant rat brain.
  Olney JW, Ikonomidou C, Mosinger JL, Frierdich G> ;The Journal of neuroscience : the official journal of the Society for Neuroscience.
• Hypobaric-ischemic conditions produce glutamate-like cytopathology in infant rat brain.
  Ikonomidou C, Price MT, Mosinger JL, Frierdich G, Labruyere J, Salles KS, Olney JW> ;The Journal of neuroscience : the official journal of the Society for Neuroscience.
• The basal ganglia, the deep prepyriform cortex, and seizure spread: bicuculline is anticonvulsant in the rat striatum.
  Turski L, Cavalheiro EA, Calderazzo-Filho LS, Bortolotto ZA, Klockgether T, Ikonomidou C, Turski WA> ;Proceedings of the National Academy of Sciences of the United States of America.
• Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy.
  Turski L, Ikonomidou C, Turski WA, Bortolotto ZA, Cavalheiro EA> ;Synapse (New York, N.Y.).
• The role of striatal cholinergic mechanisms for the development of limb rigidity: an electromyographic study in rats.
  Schwarz M, Ikonomidou C, Klockgether T, Turski L, Ellenbroek B, Sontag KH> ;Brain research.
• Effect of aminophylline on the protective action of common antiepileptic drugs against electroconvulsions in mice.
  Czuczwar SJ, Ikonomidou C, Kleinrok Z, Turski L, Turski W> ;Epilepsia.
• Effects of aminophylline and 2-chloroadenosine on seizures produced by pilocarpine in rats: morphological and electroencephalographic correlates.
  Turski WA, Cavalheiro EA, Ikonomidou C, Mello LE, Bortolotto ZA, Turski L> ;Brain research.
• Aminophylline and CGS 8216 reverse the protective action of diazepam against electroconvulsions in mice.
  Czuczwar SJ, Turski WA, Ikonomidou C, Turski L> ;Epilepsia.
• Effects of methyl beta-carboline-3-carboxylate, Ro 15-1788 and CGS 8216 on muscle tone in genetically spastic rats.
  Ikonomidou C, Turski L, Klockgether T, Schwarz M, Sontag KH> ;European journal of pharmacology.
• Effects of morphine and naloxone on pilocarpine-induced convulsions in rats.
  Turski L, Ikonomidou C, Cavalheiro EA, Kleinrok Z, Czuczwar SJ, Turski WA> ;Neuropeptides.
• Effect of aminophylline on muscle relaxant action of diazepam and phenobarbitone in genetically spastic rats: further evidence for a purinergic mechanism in the action...
  Turski L, Schwarz M, Turski WA, Ikonomidou C, Sontag KH> ;European journal of pharmacology.
• Triggers of apoptosis in the immature brain.
  Ikonomidou C> ;Brain & development.
• Sedative and anticonvulsant drugs suppress postnatal neurogenesis.
  Stefovska VG, Uckermann O, Czuczwar M, Smitka M, Czuczwar P, Kis J, Kaindl AM, Turski L, Turski WA, Ikonomidou C> ;Annals of neurology.
• Silencing of selected glutamate receptor subunits modulates cancer growth.
  Luksch H, Uckermann O, Stepulak A, Hendruschk S, Marzahn J, Bastian S, Staufner C, Temme A, Ikonomidou C> ;Anticancer research.
• Glutamate receptors in laryngeal cancer cells.
  Stepulak A, Luksch H, Uckermann O, Sifringer M, Rzeski W, Polberg K, Kupisz K, Klatka J, Kielbus M, Grabarska A, Marzahn J, Turski L, Ikonomidou C> ;Anticancer research.
• Cannabinoids enhance susceptibility of immature brain to ethanol neurotoxicity.
  Hansen HH, Krutz B, Sifringer M, Stefovska V, Bittigau P, Pragst F, Marsicano G, Lutz B, Ikonomidou C> ;Annals of neurology.
• Prenatal effects of antiepileptic drugs.
  Ikonomidou C> ;Epilepsy currents.
• Glutamate antagonists are neurotoxins for the developing brain.
  Kaindl AM, Ikonomidou C> ;Neurotoxicity research.
• Antiepileptic drugs and the developing brain.
  Kaindl AM, Asimiadou S, Manthey D, Hagen MV, Turski L, Ikonomidou C> ;Cellular and molecular life sciences : CMLS.
• Mechanisms of disease: motoneuron disease aggravated by transgenic expression of a functionally modified AMPA receptor subunit.
  Kuner R, Groom AJ, Müller G, Kornau HC, Stefovska V, Bresink I, Hartmann B, Tschauner K, Waibel S, Ludolph AC, Ikonomidou C, Seeburg PH, Turski L> ;Annals of the New York Academy of Sciences.
• Sulthiame but not levetiracetam exerts neurotoxic effect in the developing rat brain.
  Manthey D, Asimiadou S, Stefovska V, Kaindl AM, Fassbender J, Ikonomidou C, Bittigau P> ;Experimental neurology.
• Caspase-1-processed interleukins in hyperoxia-induced cell death in the developing brain.
  Felderhoff-Mueser U, Sifringer M, Polley O, Dzietko M, Leineweber B, Mahler L, Baier M, Bittigau P, Obladen M, Ikonomidou C, Bührer C> ;Annals of neurology.
• Apoptotic neurodegeneration in the context of traumatic injury to the developing brain.
  Bittigau P, Sifringer M, Felderhoff-Mueser U, Ikonomidou C> ;Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
• Anticancer agents are potent neurotoxins in vitro and in vivo.
  Rzeski W, Pruskil S, Macke A, Felderhoff-Mueser U, Reiher AK, Hoerster F, Jansma C, Jarosz B, Stefovska V, Bittigau P, Ikonomidou C> ;Annals of neurology.
• Anesthesia-induced developmental neuroapoptosis. Does it happen in humans?
  Olney JW, Young C, Wozniak DF, Ikonomidou C, Jevtovic-Todorovic V> ;Anesthesiology.
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Journal Articles

• Synaptic NMDA receptor activity boosts intrinsic antioxidant defences  
  Papadia S, Soriano FX, Leveille F, Martel M-A, Dakin KA, Hansen H, Kainld A, Sifringer M, Fowler J, Mckenzie G, Craigon M, Corriveau R, Ghaual P, Horsburgh K, Yakner B..., Nat Neurosci, 1/1/2008
• Neuronal damage after moderate hypoxia and erythropoietin  
  Weber A, Dzietko M, Berns M, Felderhoff-Muser U, Heinemann U, Maier RF, Obladen M, Ikonomidou C, Buehrer C, Neurobiol Dis, 1/1/2005
• Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain  
  Olney JW, Tenkova T, Dikranian K, Qin Y-Q, Labruyere J, Ikonomidou C, Dev Brain Res, 1/1/2002

Books/Book Chapters

• Handbook of Neurotoxicity 
  Chapter: Glutamate as a neurotoxin. 
  Page 1 - 33Turski GN, Ikonomidou CEditors: Kostrzewa RM.Springer Science and Business Media, New York, NY2013
• Neurobiology of the NMDA Receptor: From Chemistry to the Clinic. 
  Chapter: Excitotoxic mechanisms operative in youth and old age. 
  Page 187 - 202Olney JW, Ikonomidou CEditors: Kozikowski AP, Barrionuevo G.VCH Publishers, New York, NY1991
• Advances in Biosciences, Vol. 78, Excitatory Amino Acids and Brain Ischemia: Pharmacological and Clinical Aspects. 
  Chapter: Extreme sensitivity to excitotoxic brain damage in youth and old age. 
  Page 15 - 28Olney JW, Ikonomidou CEditors: Biggio G, Spano PF, Toffano G, Gessa GL.Pergamon Press, Oxford, England1990

Abstracts/Posters

• Are antiepileptic drugs neurotoxic during early postnatal development?
  N. Ikonomidou, 10th European Congress in Epileptology, London, United Kingdom, 1/1/2012
• NMDA antagonists enhance delayed neurodegeneration in the hippocampus following traumatic brain injury.
  Ikonomidou C, Turski L, Soc Neurosci Abstr; Society for Neuroscience 28th Annual Meeting, Miami, FL, 1/1/1999
• Muskelschwache als Primarsymptom bei einem 12-jahrigen Jungen mit Overlap-Myositis und bilateraler Sakroiliitis.
  Jansma C, Ikonomidou C, Scheer I, Moers A, Keitzer R, Jahrestagung der Deutschen Gesellschaft fur Kinderheilkunde und Jugendmedizin, Dresden, Deutschland, 1/2/1998
• Altersabhangigkeit der sekundaren Schaden nach mechanischem Hirntrauma.
  Bittigau P, Pohl D, Stadthaus D, Lang D, Vockler J, Hubner C, Ikonomidou C, 23rd Jahrestagung der Gesellschaft fur Neuropadiatrie, Klinikum Grobetahadern, Munchen, 1/17/1997
• CNS apoptosis: how shall it be defined and recognized?
  Ishimaru MJ, Ikonomidou C, Dikranian K, Olney JW, Soc Neurosci Abstr; Society for Neuroscience 26th Annual Meeting, New Orleans, LA, 1/1/1997
• Cysteine-induced brain damage in neonatal rats selectively affects GABAergic neurons.
  Ikonomidou C, Der TC, Sesma MA, Qin YQ, Ishimaru M, Labruyere J, Olney JW, Soc Neurosci Abstr; Society for Neuroscience 25th Annual Meeting, San Diego, CA, 1/1/1995
• Excitotoxic degeneration of motor neurons resembles that seen in SOD-1 transgenic mice.
  Olney JW, Ikonomidou C, Wang GJ, Qin YQ, Price MT, Soc Neurosci Abstr; Society for Neuroscience 25th Annual Meeting, San Diego, CA, 1/1/1995
• Protective effect of low-grade hypothermia against hypoxic/ischemic brain damage in infant rats.
  Ikonomidou C, Mosinger JL, Olney JW, 12th Biennal Meeting of the International Society for Neurochemistry, Algrave, Portugal, 1/23/1989
• NMDA antagonists produce impairment of spontaneous alternation behavior in mice.
  Parada-Turska J, Ikonomidou C, Turski WA, Soc Neurosci Abstr; Society for Neuroscience 19th Annual Meeting, Phoenix, AZ, 1/1/1989
• Aminooxyacetic acid produces excitotoxic lesions in the rt striatum.
  Urbanska E, Ikonomidou C, Sieklucka M, Turski WA, Soc Neurosci Abstr; Society for Neuroscience 19th Annual Meeting, Phoenix, AZ, 1/1/1989
• Aminooxyacetic acid produces excitotoxic lesions in the rat striatum.
  Urbanska E, Ikonomidou C, Sieklucka M, Turski WA, Book of Abstracts, 1st International Congress on Amino Acid Research, Vienna, Austria, 1/1/1989
• Effects of methyl beta-carboline-3-carboxylate, Ro 15-1788 and CGS 8216 on the muscle tone in genetically spastic rats.
  Schwarz M, Ikonomidou C, Turski L, Klockgether T, Sontag KH, Soc Neurosci Abstr; Society for Neuroscience 15th Annual Meeting, Dallas, TX, 1/1/1985
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Lectures

• Life threatening signs of pediatric systemic disease. 
  University of Saskatchewan, Saskatoon, Saskatchewan - 1/4/2010
• Pediatric ophthalmology and ocular genetics. 
  Philadelphia, PA - 1/1/2010
• Depression in the Pregnant and Postpartum Woman 
  1/1/2010
• Fetal Programming 
  Columbia University College of Physicians and Surgeons - 1/1/2010
• Retnal hemorrhages: does it mean this baby was shaken? 
  1/21/2009
• Difficult problems - non strabismus. 
  San Francisco, CA - 1/19/2009
• Non-accidental injury: Highlights from around the world’s literature illustrating work in multiple countries. 
  Barcelona, Spain - 1/13/2009
• Overview of the molecular genetics of congenital cataracts. 
  Barcelona, Spain - 1/13/2009
• Retinal hemorrhages 2009: state of the art. 
  Harrisburg, PA - 1/11/2009
• Who can do it best: staff or resident? 
  Halifax, Nova Scotia - 1/2/2009
• Advances in MS therapy. 
  Norman, OK - 1/1/2009
• Diagnostic dilemmas in MS. 
  University of Oklahoma, Oklahoma City, OK - 1/1/2009
• Abusive head injury: fact, education, and ethics for the ophthalmologist. 
  Muscat, Oman - 1/29/2008
• You want to try something new: is it ethical? Innovation ethics in clinical medicine and research. 
  St. Michael’s Hospital, Toronto, Canada - 1/14/2008
• Cataracts and anterior segment dysmorphology. 
  IWK Hospital, Dalhousie Unviersity, Halifax, Nova Scotia - 1/10/2008
• Albinism: current concepts. 
  Great Ormond Street Hospital for Children, London, United Kingdom - 1/7/2008
• Paediatric ophthalmology. 
  The Hospital for Sick Children, Toronto, Canada - 1/6/2008
• Postgraduate bioethics education: answering the call to action. 
  Toronto, Ontario, Canada - 1/31/2007
• Retinal haemorrhages: does it mean this baby has been shaken? 
  Detroit, MI - 1/27/2007
• Complementary medicine and noncompliance with glaucoma treatment in paediatrics. 
  Philadelphia, PA - 1/26/2007
• Ocular syndromology: what syndrome does this child have? 
  Philadelphia, PA - 1/25/2007
• Management of paediatric cataract. 
  Danang Eye Hospital, Danang, Vietnam - 1/12/2007
• Retinal haemorrhages: has this baby been abused. 
  Dartmouth-Hitchcock Medical Centre/Childrens Hospital at Dartmouth, Hanover, NH - 1/4/2007
• Eye genetics 2007 
  Dartmouth-Hitchcock Medical Centre/Childrens Hospital at Dartmouth, Hanover, NH - 1/3/2007
• Multiple Sclerosis; Can it be conquered? 
  Tulsa, OK - 1/1/2007
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Other

• Die muskelrelaxierende Wirkung des Phenobarbitals: eine elektromyographische Studie bei der spastischen Han-Wistar-Rattenmutante. Inaugural-Dissertation zur Erlangung ... 
  Ikonomidou C
  Georg-August-Univeristat, Goettingen - 1/1/1985