AdamBSteinMD

Cardiology • Ann Arbor, MI

Adult Congenital Heart Disease

Assistant Professor, Internal Medicine, University of Michigan Medical School

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Office
1500 East Medical Center Dr
Level 3 Cardiovascular Center
Ann Arbor, MI 48109
Phone+1 888-287-1082
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Education & Training

University of Louisville School of MedicineFellowship, Cardiovascular Disease, 2002 - 2006
Washington University/B-JH/SLCH ConsortiumResidency, Internal Medicine, 1999 - 2001
Washington University in St. Louis School of MedicineClass of 1999

Certifications & Licensure

MI State Medical License 2007 - 2026
KY State Medical License 2006 - 2008
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Publications & Presentations

PubMed

24 citations
Monocyte Subsets and Inflammatory Cytokines in Acute Decompensated Heart Failure.
Sascha N. Goonewardena, Adam B. Stein, Ryan E. Tsuchida, Rahul Rattan, Dhavan Shah, Scott L. Hummel> ;Journal of Cardiac Failure. 2016 May 1
7 citations
Design and Evaluation of Tumor-Specific Dendrimer Epigenetic Therapeutics
Hong Zong, Dhavan Shah, Katherine Selwa, Ryan E. Tsuchida, Rahul Rattan, Jay Mohan, Adam B. Stein, James B. Otis, Sascha N. Goonewardena> ;Chemistryopen. 2015 Jun 1
11 citations
The PTIP-Associated Histone Methyltransferase Complex Prevents Stress-Induced Maladaptive Cardiac Remodeling.
Adam B. Stein, Sascha N. Goonewardena, Thomas A. Jones, Parker Joseph Prusick, Ahmad A. Bazzi, Jane M. Belyavskaya, Makayla M. McCoskey, Rachel A. Dandar> ;Plos One. 2015 May 22
The chromatin remodeling protein CHD7, mutated in CHARGE syndrome, is necessary for proper craniofacial and tracheal development.
Sperry, E. D.,Hurd, E. A.,Durham, M. A.,Reamer, E. N.,Stein, A. B.,Martin, D. M.> ;Dev. Dyn.. 2014 Jul 01
67 citations
Carbon monoxide induces a late preconditioning-mimetic cardioprotective and antiapoptotic milieu in the myocardium
Adam B. Stein, Roberto Bolli, Buddhadeb Dawn, Santosh K. Sanganalmath, Yanqing Zhu, Ou Li Wang, Yiru Guo, Roberto Motterlini, Yu-Ting Xuan> ;Journal of Molecular and Cellular Cardiology. 2012 Jan 1
94 citations
Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes
Adam B. Stein, Thomas A. Jones, Todd J. Herron, Sanjeevkumar R. Patel, Sharlene M. Day, Sami F. Noujaim, Michelle L. Milstein, Matthew Klos, Philip B. Furspan, José Ja...> ;The Journal of Clinical Investigation. 2011 Jul 1
79 citations
A murine model of inducible, cardiac-specific deletion of STAT3: its use to determine the role of STAT3 in the upregulation of cardioprotective proteins by ischemic pr...
Roberto Bolli, Adam B. Stein, Yiru Guo, Ou Li Wang, Gregg Rokosh, Buddhadeb Dawn, Jeffery D. Molkentin, Santosh K. Sanganalmath, Yanqing Zhu, Yu-Ting Xuan> ;Journal of Molecular and Cellular Cardiology. 2011 Apr 1
9 citations
The beneficial effects of postinfarct cytokine combination therapy are sustained during long-term follow-up
Santosh K. Sanganalmath, Adam B. Stein, Yiru Guo, Sumit Tiwari, Greg Hunt, Robert J Vincent, Yiming Huang, Arash Rezazadeh, Suzanne T. Ildstad, Buddhadeb Dawn, Roberto...> ;Journal of Molecular and Cellular Cardiology. 2009 Oct 1
19 citations
The late phase of ischemic preconditioning induces a prosurvival genetic program that results in marked attenuation of apoptosis.
Adam B. Stein, Roberto Bolli, Yiru Guo, Ou Li Wang, Wei Tan, Wen Jian Wu, Xiaoping Zhu, Yanqing Zhu, Yu-Ting Xuan> ;Journal of Molecular and Cellular Cardiology. 2007 Jun 1
94 citations
Effects of anesthesia on echocardiographic assessment of left ventricular structure and function in rats
Adam B. Stein, Sumit Tiwari, Paul Thomas, Greg Hunt, Cemil Levent, Marcus F. Stoddard, Xian-Liang Tang, Roberto Bolli, Buddhadeb Dawn> ;Basic Research in Cardiology. 2007 Jan 1
72 citations
Postinfarct Cytokine Therapy Regenerates Cardiac Tissue and Improves Left Ventricular Function
Buddhadeb Dawn, Yiru Guo, Arash Rezazadeh, Yiming Huang, Adam B. Stein, Greg Hunt, Sumit Tiwari, Jai Varma, Yan Gu, Sumanth D. Prabhu, Jan Kajstura, Piero Anversa, Suz...> ;Circulation Research. 2006 Apr 28
41 citations
Gene therapy with iNOS provides long-term protection against myocardial infarction without adverse functional consequences
Qianhong Li, Yiru Guo, Wei Tan, Adam B. Stein, Buddhadeb Dawn, Wen Jian Wu, Xiaoping Zhu, Xiaoqin Lu, Xiaoming Xu, Tariq S. Siddiqui, Sumit Tiwari, Roberto Bolli> ;American Journal of Physiology. Heart and Circulatory Physiology. 2006 Feb 1
41 citations
Late preconditioning induced by NO donors, adenosine A1 receptor agonists, and δ1-opioid receptor agonists is mediated by iNOS
Yiru Guo, Adam B. Stein, Wen Jian Wu, Xiaoping Zhu, Wei Tan, Qianhong Li, Roberto Bolli> ;American Journal of Physiology. Heart and Circulatory Physiology. 2005 Jul 8
341 citations
Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function
Buddhadeb Dawn, Adam B. Stein, Konrad Urbanek, Marcello Rota, Brian Whang, Raffaella Rastaldo, Daniele Torella, Xian Liang Tang, Arash Rezazadeh, Jan Kajstura, Annaros...> ;Proceedings of the National Academy of Sciences of the United States of America. 2005 Mar 8
97 citations
Administration of a CO-releasing molecule induces late preconditioning against myocardial infarction.
Adam B. Stein, Yiru Guo, Wei Tan, Wen Jian Wu, Xiaoping Zhu, Qianhong Li, Cheng Luo, Buddhadeb Dawn, Tony Johnson, Roberto Motterlini, Roberto Bolli> ;Journal of Molecular and Cellular Cardiology. 2005 Jan 1
80 citations
Delayed Adaptation of the Heart to Stress Late Preconditioning
Adam B. Stein, Xian Liang Tang, Yiru Guo, Yu-Ting Xuan, Buddhadeb Dawn, Roberto Bolli> ;Stroke. 2004 Nov 1
169 citations
IL-6 plays an obligatory role in late preconditioning via JAK–STAT signaling and upregulation of iNOS and COX-2
Buddhadeb Dawn, Yu-Ting Xuan, Yiru Guo, Arash Rezazadeh, Adam B. Stein, Greg Hunt, Wen Jian Wu, Wei Tan, Roberto Bolli> ;Cardiovascular Research. 2004 Oct 1
21 citations
Hypercholesterolemia blunts NO donor-induced late preconditioning against myocardial infarction in conscious rabbits.
Xian Liang Tang, Adam B. Stein, Gregg Shirk, Roberto Bolli> ;Basic Research in Cardiology. 2004 Sep 16
57 citations
Tumor necrosis factor-α does not modulate ischemia/reperfusion injury in naïve myocardium but is essential for the development of late preconditioning
Buddhadeb Dawn, Yiru Guo, Arash Rezazadeh, Ou Li Wang, Adam B. Stein, Greg Hunt, Jai Varma, Yu-Ting Xuan, Wen Jian Wu, Wei Tan, Xiaoping Zhu, Roberto Bolli> ;Journal of Molecular and Cellular Cardiology. 2004 Jul 1
174 citations
Administration of a CO-releasing molecule at the time of reperfusion reduces infarct size in vivo.
Yiru Guo, Adam B. Stein, Wen Jian Wu, Wei Tan, Xiaoping Zhu, Qian Hong Li, Buddhadeb Dawn, Roberto Motterlini, Roberto Bolli> ;American Journal of Physiology. Heart and Circulatory Physiology. 2004 May 1
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Press Mentions

Dr. Adam Stein Raleigh, NC Helps People with Neck Lift Surgery RecoveryJuly 28th, 2018
Synergistic Research Between the Center of Arrhythmia Research and the Michigan Biology of Cardiovascular Aging at the University of MichiganNovember 10th, 2017