AjjaiShivaramAlvaMD

PubMed

• Phase II Study of Erdafitinib in Patients With Tumors WithAmplifications: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol K1.
  Jun Gong, Alain C Mita, Zihan Wei, Heather H Cheng, Edith P Mitchell, John J Wright, S Percy Ivy, Victoria Wang, Robert C Gray, Lisa M McShane, Larry V Rubinstein, Dav...> ;JCO Precision Oncology. 2024 Apr 1
• Repeat Next-Generation Sequencing Testing on Progression in Men With Metastatic Prostate Cancer Can Identify New Actionable Alterations.
  Joseph J Park, Alec Chu, Jinju Li, Alicia Ali, Rana R McKay, Clara Hwang, Matthew K Labriola, Albert Jang, Deepak Kilari, George Mo, Deepak Ravindranathan, Laura S Gra...> ;JCO Precision Oncology. 2024 Apr 1
• NCCN Guidelines® Insights: Kidney Cancer, Version 2.2024.
  Robert J Motzer, Eric Jonasch, Neeraj Agarwal, Ajjai Alva, Hilary Bagshaw, Michael Baine, Kathryn Beckermann, Maria I Carlo, Toni K Choueiri, Brian A Costello, Ithaar ...> ;Journal of the National Comprehensive Cancer Network. 2024 Feb 1
• Durvalumab and guadecitabine in advanced clear cell renal cell carcinoma: results from the phase Ib/II study BTCRC-GU16-043.
  Singer, E., Acharyya, S., Peace, D., Baladandayuthapani, V., Majumdar, A., Li, X., Lalancette, C., Kryczek, I., Zou, W., Zakharia, Y., Garje, R., Joshi, M., Alva, A.> ;Nature Communications. 2024 Feb 1
• Novel Approaches with HIF-2α Targeted Therapies in Metastatic Renal Cell Carcinoma.
  Nguyen, C., Oh, E., Bahar, P., Vaishampayan, U., Else, T., Alva, A.> ;Cancers. 2024 Jan 31
• Novel endoscopic scoring system for immune mediated colitis: A Multicenter Retrospective Study of 674 Patients.
  Wang, Y., Abu-Sbeih, H., Tang, T., Shatila, M., Faleck, D., Harris, J., Dougan, M., Olsson-Brown, A., Johnson, D., Shi, C., Grivas, P., Diamantopoulos, L., Owen, D., C...> ;Gastrointestinal Endoscopy. 2024 Jan 23
• 1 citations
  Association of Molecular Subtypes with Pathologic Response, PFS, and OS in a Phase II Study of COXEN with Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer.
  Lerner, S., McConkey, D., Tangen, C., Meeks, J., Flaig, T., Hua, X., Daneshmand, S., Alva, A., Lucia, M., Theodorescu, D., Goldkorn, A., Milowsky, M., Choi, W., Bangs,...> ;Clinical Cancer Research. 2024 Jan 17
• Co-occurring BRCA2/SPOP Mutations Predict Exceptional Poly (ADP-ribose) Polymerase Inhibitor Sensitivity in Metastatic Castration-Resistant Prostate Cancer.
  Orme, J., Taza, F., De Sarkar, N., Tewari, A., Arsalan Naqvi, S., Riaz, I., Childs, D., Omar, N., Adra, N., Ashkar, R., Cheng, H., Schweizer, M., Sokolova, A., Agarwal...> ;European Urology Oncology. 2023 Dec 9
• Biomarker-Directed Therapy in Black and White Men With Metastatic Castration-Resistant Prostate Cancer.
  Park, J., Holland, B., Jang, A., Clara Hwang, Nicholas C Henderson, Shih-Chun Chu, Brandon Holland, Frank C Cackowski, Amanda Pilling, Albert Jang, Shoshana Rothstein,...> ;JAMA Network Open. 2023 Sep 5
• Pathogenic Germline Mutational Landscape in Patients With Renal Cell Carcinoma and Associated Clinicopathologic Features.
  Charles B Nguyen, Claire Knaus, Jinju Li, Marie-Louise Accardo, Erika Koeppe, Ulka N Vaishampayan, Ajjai S Alva, Tobias Else> ;JCO Precision Oncology. 2023 Sep 1
• Survival Prediction of Patients with Bladder Cancer after Cystectomy Based on Clinical, Radiomics, and Deep-Learning Descriptors.
  Di Sun, Lubomir Hadjiiski, John Gormley, Heang-Ping Chan, Elaine M Caoili, Richard H Cohan, Ajjai Alva, Vikas Gulani, Chuan Zhou> ;Cancers. 2023 Sep 1
• Sponsor Perspectives on the Impact of the COVID-19 Pandemic on Interventional Cancer Clinical Trial Protocols and Data Quality.
  Joseph M Unger, Hillary Stires, Laura A Levit, Mark Stewart, Brittany Avin McKelvey, Beverly Canin, Emily Dressler, Keith Flaherty, Peter Fredette, Lee Jones, Peggy Mc...> ;JCO Oncology Practice. 2023 Oct 1
• 4 citations
  Pembrolizumab in Patients With Tumors With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry Study.
  Herbert L Duvivier, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Eugene R Ahn, Tareq Al Baghdadi, Ajjai S Alva, Stephanie A Dublis, Timothy L Cannon, Carmen J...> ;Journal of Clinical Oncology. 2023 Nov 20
• Clinical implications of AR alterations in advanced prostate cancer: A multi-institutional collaboration.
  Tanya Dorff, Zeynep Zengin, Nicholas Henderson, Alicia Ali, Charles Nguyen, Clara Hwang, Pedro C Barata, Mehmet Bilen, Laura Graham, George Mo, Deepak Kilari, Abhishek...> ;Research Square. 2023 Aug 10
• 4 citations
  Adjuvant everolimus after surgery for renal cell carcinoma (EVEREST): a double-blind, placebo-controlled, randomised, phase 3 trial.
  Christopher W Ryan, Catherine M Tangen, Elisabeth I Heath, Mark N Stein, Maxwell V Meng, Ajjai S Alva, Sumanta K Pal, Igor Puzanov, Joseph I Clark, Toni K Choueiri, Ne...> ;Lancet. 2023 Sep 23
• 1 citations
  Long-term Outcomes from a Phase 2 Study of Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer (SWOG S1314; NCT02177695).
  Thomas W Flaig, Catherine M Tangen, Siamak Daneshmand, Ajjai Shivaram Alva, M Scott Lucia, David James McConkey, Dan Theodorescu, Amir Goldkorn, Matthew I Milowsky, Ri...> ;European Urology. 2023 Sep 1
• 12 citations
  Outcomes for International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Groups in Contemporary First-line Combination Therapies for Metastatic Renal ...
  Ernst, M., Navani, V., Wells, J., Donskov, F., Basappa, N., Labaki, C., Pal, S., Meza, L., Wood, L., Ernst, D., Szabados, B., McKay, R., Parnis, F., Suarez, C., Yuasa,...> ;European Urology. 2023 Jul 1
• 9 citations
  Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy.
  Noy Cohen Saban, Adam Yalin, Tomer Landsberger, Ran Salomon, Ajjai Alva, Tali Feferman, Ido Amit, Rony Dahan> ;Science Immunology. 2023 Mar 10
• 38 citations
  Upfront Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma Treated with Immune Checkpoint Inhibitors or Targeted Therapy: An Observational Study from the In...
  Ziad Bakouny, Talal El Zarif, Shaan Dudani, J Connor Wells, Chun Loo Gan, Frede Donskov, Julia Shapiro, Ian D Davis, Francis Parnis, Praful Ravi, John A Steinharter, N...> ;European Urology. 2023 Feb 1
• 3 citations
  Differential responses to taxanes and PARP inhibitors in ATM- versus BRCA2-mutated metastatic castrate-resistant prostate cancer.
  Christopher T Su, Emily Nizialek, Jacob E Berchuck, Panagiotis J Vlachostergios, Ryan Ashkar, Alexandra Sokolova, Pedro C Barata, Rahul R Aggarwal, Rana R McKay, Neera...> ;The Prostate. 2023 Feb 1
• 1 citations
  Characterization of Patients With Metastatic Renal Cell Carcinoma Experiencing Complete Response to First-line Therapies: Results From the International Metastatic Ren...
  Kosuke Takemura, Vishal Navani, Matthew S Ernst, J Connor Wells, Luis Meza, Sumanta K Pal, Jae-Lyun Lee, Haoran Li, Neeraj Agarwal, Ajjai S Alva, Aaron R Hansen, Navee...> ;The Journal of Urology. 2023 Apr 1
• 1 citations
  A Phase 2 Trial of Nab-paclitaxel in Combination With Anti-PD1 Therapy in Advanced Urothelial Cancer.
  Irene Tsung, Edward Green, Phillip Palmbos, Zachery Sloan, Zachery R Reichert, Ulka Vaishampayan, David C Smith, Megan E V Caram, Sarah Yentz, Stephanie Daignault-Newt...> ;The Journal of Urology. 2023 Jan 1
• 16 citations
  First-in-human phase 1/1b study to evaluate sitravatinib in patients with advanced solid tumors.
  Todd Bauer, Byong Chul Cho, Rebecca Heist, Lyudmila Bazhenova, Theresa Werner, Sanjay Goel, Dong-Wan Kim, Douglas Adkins, Richard D Carvajal, Ajjai Alva, Keith Eaton, ...> ;Investigational New Drugs. 2022 Oct 1
• 6 citations
  Association of the Time to Immune Checkpoint Inhibitor (ICI) Initiation and Outcomes With Second Line ICI in Patients With Advanced Urothelial Carcinoma.
  Rafee Talukder, Dimitrios Makrakis, Genevieve Ihsiu Lin, Leonidas N Diamantopoulos, Scott Dawsey, Shilpa Gupta, Lucia Carril-Ajuria, Daniel Castellano, Ivan de Kouchko...> ;Clinical Genitourinary Cancer. 2022 Dec 1
• 8 citations
  Association Between Sites of Metastasis and Outcomes With Immune Checkpoint Inhibitors in Advanced Urothelial Carcinoma.
  Dimitrios Makrakis, Rafee Talukder, Genevieve Ihsiu Lin, Leonidas N Diamantopoulos, Scott Dawsey, Shilpa Gupta, Lucia Carril-Ajuria, Daniel Castellano, Ivan de Kouchko...> ;Clinical Genitourinary Cancer. 2022 Oct 1
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Journal Articles

• Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors  
  Erin F Cobain, Francis Worden, Scott M Schuetze, Mark M Zalupski, Vaibhav Sahai, Ajjai Alva, Anne F Schott, Moshe Talpaz, JAMA Oncology
• Evaluation of the Safety and Efficacy of Immunotherapy Rechallenge in Patients with Renal Cell Carcinoma  
  Praful Ravi, Charlene Mantia, Christopher Su, Neeraj Agarwal, Yousef Zakharia, Rana R Mckay, Vivek Narayan, Ajjai Alva, Bradley A Mcgregor, David F Mcdermott, Toni K C..., JAMA Oncology
• Frequent PD-L1 Protein Expression and Molecular Correlates in Urinary Bladder Squamous Cell Carcinoma  
  Aaron M Udager, Andrew S Mcdaniel, Simpa S Salami, Samuel D Kaffenberger, Jeffrey S Montgomery, Alon Z Weizer, Zachery R Reichert, Ajjai S Alva, Arul M Chinnaiyan, Sco..., European Urology
• Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer  
  Arul M Chinnaiyan, Ajjai S Alva, Clinical Cancer Research
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Lectures

• Pembrolizumab (P) in patients (pts) with metastatic breast cancer (MBC) with high tumor mutational burden (HTMB): Results from the Targeted Agent and Profiling Utiliza... 
  2019 ASCO Annual Meeting - 6/1/2019