AnathShalevMD

PubMed

• 1 citations
  Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling.
  Guanlan Xu, Junqin Chen, Brian Lu, Praveen Sethupathy, Wei-Jun Qian, Anath Shalev> ;Diabetes. 2023 Oct 1
• An approach for collaborative development of a federated biomedical knowledge graph-based question-answering system: Question-of-the-Month challenges.
  Karamarie Fecho, Chris Bizon, Tursynay Issabekova, Sierra Moxon, Anne E Thessen, Shervin Abdollahi, Sergio E Baranzini, Basazin Belhu, William E Byrd, Lawrence Chung, ...> ;Journal of Clinical and Translational Science. 2023 Jan 1
• 2 citations
  LDB1-mediated transcriptional complexes are sensitive to islet stress.
  Yanping Liu, Jessica D Kepple, Anath Shalev, Chad S Hunter> ;Islets. 2022 Dec 31
• 1 citations
  Alpha Cell Thioredoxin-interacting Protein Deletion Improves Diabetes-associated Hyperglycemia and Hyperglucagonemia.
  Brian Lu, Junqin Chen, Guanlan Xu, Truman B Grayson, Gu Jing, SeongHo Jo, Anath Shalev> ;Endocrinology. 2022 Oct 11
• Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice.
  Teayoun Kim, Shelly Nason, Jessica Antipenko, Brian Finan, Anath Shalev, Richard DiMarchi, Kirk M Habegger> ;Diabetes. 2022 Oct 1
• 5 citations
  Deletion of Gdf15 Reduces ER Stress-induced Beta-cell Apoptosis and Diabetes.
  Guanlan Xu, Junqin Chen, SeongHo Jo, Truman B Grayson, Sasanka Ramanadham, Akio Koizumi, Emily L Germain-Lee, Se-Jin Lee, Anath Shalev> ;Endocrinology. 2022 May 1
• 20 citations
  Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes.
  Guanlan Xu, Tiffany D Grimes, Truman B Grayson, Junqin Chen, Lance A Thielen, Hubert M Tse, Peng Li, Matt Kanke, Tai-Tu Lin, Athena A Schepmoes, Adam C Swensen, Vladis...> ;Nature Communications. 2022 Mar 3
• 1 citations
  From type 1 diabetes biology to therapy: The Human Islet Research Network.
  John S. Kaddis, Layla Rouse, Audrey Parent, Diane C. Saunders, Anath Shalev, Cherie L. Stabler, Doris A. Stoffers, Bridget K. Wagner, Joyce C. Niland> ;Molecular Metabolism. 2021 Jul 3
• 88 citations
  Metformin Use Is Associated With Reduced Mortality in a Diverse Population With COVID-19 and Diabetes.
  Andrew B. Crouse, Tiffany Grimes, Peng Li, Matthew Might, Fernando Ovalle, Anath Shalev> ;Frontiers in Endocrinology. 2021 Jan 13
• Human Glucagon Expression Is under the Control of miR-320a.
  SeongHo Jo, Guanlan Xu, Gu Jing, Junqin Chen, Anath Shalev> ;Endocrinology. 2021 Mar 1
• 55 citations
  METFORMIN USE IS ASSOCIATED WITH REDUCED MORTALITY IN A DIVERSE POPULATION WITH COVID-19 AND DIABETES.
  Andrew B. Crouse, Tiffany Grimes, Peng Li, Matthew Might, Fernando Ovalle, Anath Shalev> ;Medrxiv. 2020 Jul 31
• 43 citations
  Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action
  Lance A. Thielen, Junqin Chen, Gu Jing, Omar Moukha-Chafiq, Guanlan Xu, Seong Ho Jo, Truman Grayson, Brian Lu, Peng Li, Corinne E. Augelli-Szafran, Mark J. Suto, Matt ...> ;Cell Metabolism. 2020 Sep 1
• 10 citations
  A Small Molecule, UAB126, Reverses Diet-Induced Obesity and its Associated Metabolic Disorders.
  Guang Ren, Teayoun Kim, Hae-Suk Kim, Martin E. Young, Donald D. Muccio, Venkatram R. Atigadda, Samuel I. Blum, Hubert M. Tse, Kirk M. Habegger, Sushant Bhatnagar, Tatj...> ;Diabetes. 2020 Jul 1
• 26 citations
  Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss.
  Guanlan Xu, Lance A. Thielen, Junqin Chen, Truman Grayson, Tiffany Grimes, S. Louis Bridges, Hubert M. Tse, Blair Smith, Rakesh P. Patel, Peng Li, Carmella Evans-Molin...> ;American Journal of Physiology. Endocrinology and Metabolism. 2019 Oct 1
• 114 citations
  Verapamil and beta cell function in adults with recent-onset type 1 diabetes.
  Fernando Ovalle, Tiffany Grimes, Guanlan Xu, Anish Patel, Truman Grayson, Lance A. Thielen, Peng Li, Anath Shalev> ;Nature Medicine. 2018 Jul 9
• 67 citations
  Diabetes pathogenic mechanisms and potential new therapies based upon a novel target called TXNIP.
  Lance A. Thielen, Anath Shalev> ;Current Opinion in Endocrinology, Diabetes, and Obesity. 2018 Apr 1
• 45 citations
  miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function
  Seong Ho Jo, Junqin Chen, Guanlan Xu, Truman Grayson, Lance A. Thielen, Anath Shalev> ;Diabetes. 2017 Nov 3
• 5 citations
  Encapsulation of Human Islets Using a Biomimetic Self-Assembled Nanomatrix Gel for Protection against Cellular Inflammatory Responses.
  Patrick T. J. Hwang, Dishant K. Shah, Jacob A. Garcia, Grant C. Alexander, Dong-Jin Lim, Wanxing Cui, David K. C. Cooper, Anath Shalev, Tatsuya Kin, Jeong-a Kim, Ho-Wo...> ;ACS Biomaterials Science & Engineering. 2017 Jul 28
• 27 citations
  Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop
  Gu Jing, Junqin Chen, Guanlan Xu, Anath Shalev> ;Molecular Metabolism. 2016 Dec 1
• 2 citations
  Keeping tabs on fructose.
  Anath Shalev> ;Elife. 2016 Oct 11
• 21 citations
  Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice
  Rodrigo A. Peliciari-Garcia, Mehak Goel, Jonathan A. Aristorenas, Krishna Shah, Lan He, Qinglin Yang, Anath Shalev, Shannon M. Bailey, Sumanth D. Prabhu, John C. Chath...> ;Biochimica Et Biophysica Acta. 2016 Oct 1
• 40 citations
  miR-204 Targets PERK and Regulates UPR Signaling and β-Cell Apoptosis
  Guanlan Xu, Junqin Chen, Gu Jing, Truman Grayson, Anath Shalev> ;Molecular Endocrinology. 2016 Jul 6
• 23 citations
  TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling
  Junqin Chen, Martin E. Young, John C. Chatham, David K. Crossman, Louis J. Dell'Italia, Anath Shalev> ;American Journal of Physiology. Heart and Circulatory Physiology. 2016 Jul 1
• 37 citations
  Calcium channel blocker use is associated with lower fasting serum glucose among adults with diabetes from the REGARDS study
  Yulia Khodneva, Anath Shalev, Stuart J. Frank, April P. Carson, Monika M. Safford> ;Diabetes Research and Clinical Practice. 2016 May 1
• 38 citations
  Cytokines Regulate β-Cell Thioredoxin-interacting Protein (TXNIP) via Distinct Mechanisms and Pathways.
  Kyunghee Hong, Guanlan Xu, Truman Grayson, Anath Shalev> ;The Journal of Biological Chemistry. 2016 Apr 15
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Lectures

• miR-200 Family Members Are Induced by TXNIP and Increase ß-Cell Apoptosis 
  Birmingham, AL - 6/14/2014
• Oxidative Stress Cannot Mimic TXNIP-induced microRNA Expression in INS-1 Beta Cells 
  Birmingham, AL - 6/16/2014
• Thioredoxin-Interacting Protein (TXNIP) Regulates Beta-Cell Function Through miRNAs 
  Birmingham, AL - 6/16/2014
• Differential Cytokine Effects on ß-Cell TXNIP Expression 
  Birmingham, AL - 6/15/2014
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