AnupamaUpadhyayMD

PubMed

• An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases.
  Upadhyay, A. K., Rotili, D., Han, J. W., Hu, R., Chang, Y., Labella, D., Zhang, X., Yoon, Y. S., Mai, A., Cheng, X.> ;J Mol Biol. 2012 Feb 24
• 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
  Szulwach, K. E., Li, X., Li, Y., Song, C. X., Wu, H., Dai, Q., Irier, H., Upadhyay, A. K., Gearing, M., Levey, A. I., Vasanthakumar, A., Godley, L. A., Chang, Q., Chen...> ;Nat Neurosci. 2011 Dec
• Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor.
  Zhao, J., Du, Y., Horton, J. R., Upadhyay, A. K., Lou, B., Bai, Y., Zhang, X., Du, L., Li, M., Wang, B., Zhang, L., Barbieri, J. T., Khuri, F. R., Cheng, X., Fu, H.> ;Proc Natl Acad Sci U S A. 2011 Sep 27
• Coordinated methyl-lysine erasure: structural and functional linkage of a Jumonji demethylase domain and a reader domain.
  Upadhyay, A. K., Horton, J. R., Zhang, X., Cheng, X.> ;Curr Opin Struct Biol. 2011 Dec
• Structural basis for human PHF2 Jumonji domain interaction with metal ions.
  Horton, J. R., Upadhyay, A. K., Hashimoto, H., Zhang, X., Cheng, X.> ;J Mol Biol. 2011 Feb 11
• A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.
  Estève, P. O., Chang, Y., Samaranayake, M., Upadhyay, A. K., Horton, J. R., Feehery, G. R., Cheng, X., Pradhan, S.> ;Nat Struct Mol Biol. 2011 Jan
• Dynamics of histone lysine methylation: structures of methyl writers and erasers.
  Upadhyay, A. K., Cheng, X.> ;Prog Drug Res. 2011
• hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing.
  Lee, C. F., Ou, D. S., Lee, S. B., Chang, L. H., Lin, R. K., Li, Y. S., Upadhyay, A. K., Cheng, X., Wang, Y. C., Hsu, H. S., Hsiao, M., Wu, C. W., Juan, L. J.> ;J Clin Invest. 2010 Aug
• Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
  Horton, J. R., Upadhyay, A. K., Qi, H. H., Zhang, X., Shi, Y., Cheng, X.> ;Nat Struct Mol Biol. 2010 Jan
• Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases.
  Edmondson, D. E., Binda, C., Wang, J., Upadhyay, A. K., Mattevi, A.> ;Biochemistry. 2009 May 26
• Development of spin-labeled pargyline analogues as specific inhibitors of human monoamine oxidases A and B.
  Upadhyay, A. K., Edmondson, D. E.> ;Biochemistry. 2009 May 12
• Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
  Chang, Y., Zhang, X., Horton, J. R., Upadhyay, A. K., Spannhoff, A., Liu, J., Snyder, J. P., Bedford, M. T., Cheng, X.> ;Nat Struct Mol Biol. 2009 Mar 01
• Membrane tetraheme cytochrome c(m552) of the ammonia-oxidizing nitrosomonas europaea: a ubiquinone reductase.
  Kim, H. J., Zatsman, A., Upadhyay, A. K., Whittaker, M., Bergmann, D., Hendrich, M. P., Hooper, A. B.> ;Biochemistry. 2008 Jun 24
• Characterization of detergent purified recombinant rat liver monoamine oxidase B expressed in Pichia pastoris.
  Upadhyay, A. K., Edmondson, D. E.> ;Protein Expr Purif. 2008 Jun
• Determination of the oligomeric states of human and rat monoamine oxidases in the outer mitochondrial membrane and octyl beta-D-glucopyranoside micelles using pulsed d...
  Upadhyay, A. K., Borbat, P. P., Wang, J., Freed, J. H., Edmondson, D. E.> ;Biochemistry. 2008 Feb 12
• Comparison of the structural properties of the active site cavities of human and rat monoamine oxidase A and B in their soluble and membrane-bound forms.
  Upadhyay, A. K., Wang, J., Edmondson, D. E.> ;Biochemistry. 2008 Jan 15
• NO reductase activity of the tetraheme cytochrome C554 of Nitrosomonas europaea.
  Upadhyay, A. K., Hooper, A. B., Hendrich, M. P.> ;J Am Chem Soc. 2006 Apr 5
• Spectroscopic characterization and assignment of reduction potentials in the tetraheme cytochrome C554 from Nitrosomonas europaea.
  Upadhyay, A. K., Petasis, D. T., Arciero, D. M., Hooper, A. B., Hendrich, M. P.> ;J Am Chem Soc. 2003 Feb 19
• Spectroscopic characterization of the NO adduct of hydroxylamine oxidoreductase.
  Hendrich, M. P., Upadhyay, A. K., Riga, J., Arciero, D. M., Hooper, A. B.> ;Biochemistry. 2002 Apr 9
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