AparnaRajParikhMD

PubMed

• RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer.
  Harshabad Singh, Pranshu Sahgal, Kevin Kapner, Steven M Corsello, Hersh Gupta, Rahul Gujrathi, Yvonne Y Li, Andrew D Cherniack, Raquelle El Alam, Joseph Kerfoot, Eliza...> ;Clinical Cancer Research. 2024 Apr 15
• Modified FOLFOX6 plus bevacizumab with and without nivolumab for first-line treatment of metastatic colorectal cancer: phase 2 results from the CheckMate 9X8 randomize...
  Heinz-Josef Lenz, Aparna Parikh, David R Spigel, Allen L Cohn, Takayuki Yoshino, Mark Kochenderfer, Elena Elez, Spencer H Shao, Dustin Deming, Regan Holdridge, Timothy...> ;Journal for Immunotherapy of Cancer. 2024 Mar 13
• Discordance in Recommendation Between Next-Generation Sequencing Test Reports and Molecular Tumor Boards in India.
  Aju Mathew, Sissmol Davis, Jeffrey Mathew Boby, Anu R I, Moushumi Suryavanshi, Shaheenah S Dawood, Pankaj Kumar Panda, Shona Milon Nag, Arunangshu Das, Nitesh Rohatgi,...> ;JCO Global Oncology. 2024 Mar 1
• 5 citations
  Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker.
  Taylor, M., Wu, C., Fridy, P., Zhang, S., Senussi, Y., Wolters, J., Cajuso, T., Cheng, W., Heaps, J., Miller, B., Mori, K., Cohen, L., Jiang, H., Molloy, K., Chait, B....> ;Cancer Discovery. 2023 Dec 12
• DNA Damage by Radiopharmaceuticals and Mechanisms of Cellular Repair.
  Yousef Khazaei Monfared, Pedram Heidari, Samuel J Klempner, Umar Mahmood, Aparna R Parikh, Theodore S Hong, Matthew R Strickland, Shadi A Esfahani> ;Pharmaceutics. 2023 Dec 12
• Recent Advances in the Management of Anal Cancer.
  Hartzell, M., Upadhyay, L., Parikh, A., Strickland, M., Klempner, S., Malla, M.> ;Healthcare. 2023 Nov 21
• Patient-Reported Outcomes, Tumor Markers, and Survival Outcomes in Advanced GI Cancer.
  Joy X Jarnagin, Anurag Saraf, Islam Baiev, Gary Chi, Emily E van Seventer, Amirkasra Mojtahed, Jill N Allen, Jeffrey W Clark, Lawrence Blaszkowsky, Bruce J Giantonio, ...> ;JAMA Network Open. 2023 Nov 1
• Novel Clinical Tool to Estimate Risk of False-Negative KRAS Mutations in Circulating Tumor DNA Testing.
  Stefania Napolitano, Aparna R Parikh, Jason Henry, Christine M Parseghian, Jason Willis, Kanwal P Raghav, Van K Morris, Benny Johnson, Bryan K Kee, Arvind N Dasari, Mi...> ;JCO Precision Oncology. 2023 Sep 1
• 1 citations
  Outcome of Patients With Early-Stage Mismatch Repair Deficient Colorectal Cancer Receiving Neoadjuvant Immunotherapy: A Systematic Review.
  Sakti Chakrabarti, Udhayvir Singh Grewal, Kruti Bhagirath Vora, Aparna Raj Parikh, Diana Almader-Douglas, Amit Mahipal, Mohamad Bassam B Sonbol> ;JCO Precision Oncology. 2023 Aug 1
• 1 citations
  The room where it happens: addressing diversity, equity, and inclusion in National Clinical Trials Network clinical trial leadership.
  Rebecca A Snyder, Barbara Burtness, May Cho, Jaydira Del Rivero, Deborah B Doroshow, Kathryn E Hitchcock, Aparna Kalyan, Christina A Kim, Jelena Lukovic, Aparna R Pari...> ;Journal of the National Cancer Institute. 2023 Oct 9
• 2 citations
  Dose-escalation trial of combination dabrafenib, trametinib, and AT13387 in patients with BRAF-mutant solid tumors.
  Meghan J Mooradian, James M Cleary, Anita Giobbie-Hurder, Lancia N F Darville, Aparna Parikh, Elizabeth I Buchbinder, Justine V Cohen, Donald P Lawrence, Geoffrey I Sh...> ;Cancer. 2023 Jun 15
• 1 citations
  Correction to: A phase I, first-in-human study of TAK-164, an antibody-drug conjugate, in patients with advanced gastrointestinal cancers expressing guanylyl cyclase C.
  Richard Kim, Alexis D Leal, Aparna Parikh, David P Ryan, Shining Wang, Brittany Bahamon, Neeraj Gupta, Aaron Moss, Joanna Pye, Harry Miao, Haig Inguilizian, James M Cl...> ;Cancer Chemotherapy and Pharmacology. 2023 Apr 1
• 3 citations
  A phase I, first-in-human study of TAK-164, an antibody-drug conjugate, in patients with advanced gastrointestinal cancers expressing guanylyl cyclase C.
  Richard Kim, Alexis D Leal, Aparna Parikh, David P Ryan, Shining Wang, Brittany Bahamon, Neeraj Gupta, Aaron Moss, Joanna Pye, Harry Miao, Haig Inguilizian, James M Cl...> ;Cancer Chemotherapy and Pharmacology. 2023 Apr 1
• 24 citations
  Combined PD-1, BRAF and MEK inhibition in BRAFcolorectal cancer: a phase 2 trial.
  Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian Hess, Kelly Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, To...> ;Nature Medicine. 2023 Feb 1
• 1 citations
  The emerging promise of liquid biopsies in solid tumors.
  Leontios Pappas, Viktor A Adalsteinsson, Aparna R Parikh> ;Nature Cancer. 2022 Dec 1
• Challenges associated with the integration of immuno-oncology agents in clinical practice.
  Patrice Lazure, Aparna R Parikh, Neal E Ready, Marianne J Davies, Sophie Péloquin, Jeffrey M Caterino, Robert Lewandowski, Alexander J Lazar, Suzanne Murray> ;BMC Medical Education. 2022 Nov 12
• 10 citations
  Optimal Neoadjuvant Strategies for Locally Advanced Rectal Cancer by Risk Assessment and Tumor Location.
  Anurag Saraf, Hannah J Roberts, Jennifer Y Wo, Aparna R Parikh> ;Journal of the National Comprehensive Cancer Network. 2022 Oct 1
• 39 citations
  The clinical landscape of cell-free DNA alterations in 1671 patients with advanced biliary tract cancer.
  J E Berchuck, F Facchinetti, D F DiToro, I Baiev, U Majeed, S Reyes, C Chen, K Zhang, R Sharman, P L S Uson Junior, J Maurer, R T Shroff, C C Pritchard, M-J Wu, D V T ...> ;Annals of Oncology. 2022 Dec 1
• ASO Visual Abstract: Molecular Basis of Extramural Vascular Invasion (EMVI) in Colorectal Carcinoma : Tumor Microenvironment in EMVI-Positive Colorectal Carcinoma.
  Swati Sonal, Vikram Deshpande, David T Ting, James C Cusack, Aparna R Parikh, Azfar Neyaz, Amaya Pankaj, Martin S Taylor, Anne M Dinaux, Lieve G J Leijssen, Chloe Boud...> ;Annals of Surgical Oncology. 2022 Nov 1
• 54 citations
  Using Circulating Tumor DNA in Colorectal Cancer: Current and Evolving Practices.
  Midhun Malla, Jonathan M Loree, Pashtoon Murtaza Kasi, Aparna Raj Parikh> ;Journal of Clinical Oncology. 2022 Aug 20
• 2 citations
  Molecular Basis of Extramural Vascular Invasion (EMVI) in Colorectal Carcinoma.
  Swati Sonal, Vikram Deshpande, David T Ting, James C Cusack, Aparna R Parikh, Azfar Neyaz, Amaya Pankaj, Martin S Taylor, Anne M Dinaux, Lieve G J Leijssen, Chloe Boud...> ;Annals of Surgical Oncology. 2022 Nov 1
• 4 citations
  Implementation and Clinical Adoption of Precision Oncology Workflows Across a Healthcare Network.
  Dora Dias-Santagata, Rebecca S Heist, Adam Z Bard, Annacarolina F L da Silva, Ibiayi Dagogo-Jack, Valentina Nardi, Lauren L Ritterhouse, Laura M Spring, Nicholas Jesso...> ;The Oncologist. 2022 Nov 3
• 9 citations
  Supportive Oncology Care at Home Intervention for Patients With Pancreatic Cancer.
  Ryan D Nipp, Eva Gaufberg, Charu Vyas, Chinenye Azoba, Carolyn L Qian, Jordon Jaggers, Colin D Weekes, Jill N Allen, Eric J Roeland, Aparna R Parikh, Laurie Miller, Je...> ;JCO Oncology Practice. 2022 Oct 1
• 8 citations
  Finding Waldo: The Evolving Paradigm of Circulating Tumor DNA (ctDNA)-Guided Minimal Residual Disease (MRD) Assessment in Colorectal Cancer (CRC).
  Sakti Chakrabarti, Anup Kumar Kasi, Aparna R Parikh, Amit Mahipal> ;Cancers. 2022 Jun 23
• 15 citations
  Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer.
  Mihir Rajurkar, Aparna R Parikh, Alexander Solovyov, Eunae You, Anupriya S Kulkarni, Chong Chu, Katherine H Xu, Christopher Jaicks, Martin S Taylor, Connie Wu, Katheri...> ;Cancer Discovery. 2022 Jun 2
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Journal Articles

• Association Between Very Small Tumor Size and Decreased Overall Survival in Node-Positive Pancreatic Cancer  
  Harvey J Mamon, Paul L Nguyen, Theodore S Hong, Aparna Parikh, Jennifer Y Wo, Rinaa S Punglia, Cristina Ferrone, Ryan D Nipp, Annals of Surgical Oncology

Lectures

• Phase II study of lamivudine in p53 mutant metastatic colorectal cancer (mCRC). 
  ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/25/2020
• The role of circulating tumor DNA (ctDNA), tumor markers (TMs), and patient-reported outcomes (PROs) in predicting treatment response in patients with metastatic gastr... 
  ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/23/2020
• A phase II study of ipilimumab and nivolumab with radiation in microsatellite stable (MSS) metastatic colorectal adenocarcinoma (mCRC). 
  2019 ASCO Annual Meeting - 6/1/2019
• A plasma-only integrated genomic and epigenomic circulating tumor DNA (ctDNA) assay to inform recurrence risk in colorectal cancer (CRC). 
  2019 ASCO Annual Meeting - 6/1/2019
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