ArthurJacobsonMD

PubMed

• 33 citations
  Heroin-HIV-1 (H2) vaccine: induction of dual immunologic effects with a heroin hapten-conjugate and an HIV-1 envelope V2 peptide with liposomal lipid A as an adjuvant.
  Oscar B. Torres, Gary R. Matyas, Mangala Rao, Kristina K. Peachman, Rashmi Jalah, Zoltan Beck, Nelson L. Michael, Kenner C. Rice, Arthur E. Jacobson, Carl R. Alving> ;NPJ Vaccines. 2017 May 2
• 16 citations
  A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse.
  Oscar B. Torres, Joshua F. G. Antoline, Fuying Li, Rashmi Jalah, Arthur E. Jacobson, Kenner C. Rice, Carl R. Alving, Gary R. Matyas> ;Analytical and Bioanalytical Chemistry. 2016 Feb 1
• 15 citations
  Chiral Resolution and Absolute Configuration of the Enantiomers of the Psychoactive “Designer Drug” 3,4‐Methylenedioxypyrovalerone
  Masaki Suzuki, Jeffrey R. Deschamps, Arthur E. Jacobson, Kenner C. Rice> ;Chirality. 2015 Apr 1
• 32 citations
  Characterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines
  Oscar B. Torres, Rashmi Jalah, Kenner C. Rice, Fuying Li, Joshua F. G. Antoline, Malliga R. Iyer, Arthur E. Jacobson, Mohamed Nazim Boutaghou, Carl R. Alving, Gary R. ...> ;Analytical and Bioanalytical Chemistry. 2014 Aug 2
• 37 citations
  Facial recognition of heroin vaccine opiates: type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine,...
  Gary R. Matyas, Kenner C. Rice, Kejun Cheng, Fuying Li, Joshua F. G. Antoline, Malliga R. Iyer, Arthur E. Jacobson, Alexander V. Mayorov, Zoltan Beck, Oscar B. Torres,...> ;Vaccine. 2014 Mar 14
• Interface Effects on the Electronic Transport Properties in Highly Epitaxial LaBaCo2O5.5+δ Films.
  Ma, C. R.,Liu, M.,Liu, J.,Collins, G.,Zhang, Y. M.,Wang, H. B.,Chen, C. L.,Lin, Y.,He, J.,Jiang, J. C.,Meletis, E. I.,Jacobson, A. J.> ;ACS Appl Mater Interfaces. 2014 Jan 29
• 61 citations
  Liposomes containing monophosphoryl lipid A: A potent adjuvant system for inducing antibodies to heroin hapten analogs
  Gary R. Matyas, Alexander V. Mayorov, Kenner C. Rice, Arthur E. Jacobson, Kejun Cheng, Malliga R. Iyer, Fuying Li, Zoltan Beck, Kim D. Janda, Carl R. Alving> ;Vaccine. 2013 Jun 10
• 10 citations
  Z and E rotamers of N-formyl-1-bromo-4-hydroxy-3-methoxymorphinan-6-one and their interconversion as studied by 1H/13C NMR spectroscopy and quantum chemical calculations
  Agnieszka Sulima, Kejun Cheng, Arthur E. Jacobson, Kenner C. Rice, Klaus Gawrisch, Yong-Sok Lee> ;Magnetic Resonance in Chemistry. 2013 Feb 1
• 2 citations
  Diastereoselective one-pot synthesis of 7- and 8-substituted 5-phenylmorphans.
  Hwan Jung Lim, Jeffrey R. Deschamps, Arthur E. Jacobson, Kenner C. Rice> ;Organic Letters. 2011 Oct 7
• 6 citations
  Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide...
  Feng Li, John E. Folk, Kejun Cheng, Muneaki Kurimura, Jason A. Deck, Jeffrey R. Deschamps, Richard B. Rothman, Christina M. Dersch, Arthur E. Jacobson, Kenner C. Rice> ;Bioorganic & Medicinal Chemistry. 2011 Jul 15
• 7 citations
  Probes for narcotic receptor mediated phenomena. Part 42: synthesis and in vitro pharmacological characterization of the N-methyl and N-phenethyl analogues of the race...
  Jin-Hee Kim, Jeffrey R. Deschamps, Richard B. Rothman, Christina M. Dersch, John E. Folk, Kejun Cheng, Arthur E. Jacobson, Kenner C. Rice> ;Bioorganic & Medicinal Chemistry. 2011 Jun 1
• 12 citations
  Probes for narcotic receptor mediated phenomena. 41. Unusual inverse μ-agonists and potent μ-opioid antagonists by modification of the N-substituent in enantiomeric 5-...
  Kejun Cheng, Yong Sok Lee, Richard B. Rothman, Christina M. Dersch, Ross W. Bittman, Arthur E. Jacobson, Kenner C. Rice> ;Journal of Medicinal Chemistry. 2011 Jan 19
• 14 citations
  Evidence for noncompetitive modulation of substrate-induced serotonin release
  Richard B. Rothman, Michael H. Baumann, Bruce E. Blough, Arthur E. Jacobson, K. C. Rice, John S. Partilla> ;Synapse. 2010 Nov 1
• 35 citations
  Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist.
  Marina Vardanyan, Ohannes K. Melemedjian, Theodore J. Price, Michael H. Ossipov, Josephine Lai, Edward Roberts, Terrence L. Boos, Jeffrey R. Deschamps, Arthur E. Jacob...> ;Pain. 2010 Nov 1
• 21 citations
  Identification of a Novel “Almost Neutral” μ-opioid Receptor Antagonist in CHO Cells Expressing the Cloned Human μ-opioid Receptor
  Elliott J. Sally, Heng Xu, Christina M. Dersch, Ling-Wei Hsin, Li-Te Chang, Thomas E. Prisinzano, Denise S. Simpson, Denise Giuvelis, K. C. Rice, Arthur E. Jacobson, K...> ;Synapse. 2010 Apr 1
• 4 citations
  Probes for narcotic receptor mediated phenomena. 40. N-Substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ols
  Malliga R. Iyer, Yong Sok Lee, Jeffrey R. Deschamps, Richard B. Rothman, Christina M. Dersch, Arthur E. Jacobson, Kenner C. Rice> ;Bioorganic & Medicinal Chemistry. 2010 Jan 1
• 6 citations
  Probes for narcotic receptor mediated phenomena. 39. Enantiomeric N-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged ...
  Yi Zhang, Yong Sok Lee, Richard B. Rothman, Christina M. Dersch, Jeffrey R. Deschamps, Arthur E. Jacobson, Kenner C. Rice> ;Journal of Medicinal Chemistry. 2009 Dec 10
• 16 citations
  Probes for narcotic receptor mediated phenomena. 37. Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-iso...
  Muneaki Kurimura, Hehua Liu, Agnieszka Sulima, Akihiro Hashimoto, Anna K. Przybył, Etsuo Ohshima, Shinichi Kodato, Jeffrey R. Deschamps, Christina M. Dersch, Richard B...> ;Journal of Medicinal Chemistry. 2008 Dec 25
• 13 citations
  Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans
  Josef Zezula, Lisa Singer, Anna K. Przybył, Akihiro Hashimoto, Christina M. Dersch, Richard B. Rothman, Jeffrey R. Deschamps, Yong Sok Lee, Arthur E. Jacobson, Kenner ...> ;Organic & Biomolecular Chemistry. 2008 Jul 31
• 8 citations
  Design and synthesis of 2- and 3-substituted-3-phenylpropyl analogs of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)e...
  Ling-Wei Hsin, Li-Te Chang, Richard B. Rothman, Christina M. Dersch, Arthur E. Jacobson, Kenner C. Rice> ;Journal of Medicinal Chemistry. 2008 Apr 5
• 18 citations
  Opioid ligands with mixed properties from substituted enantiomeric N-phenethyl-5-phenylmorphans. Synthesis of a µ-agonist δ-antagonist and δ-inverse agonists
  Kejun Cheng, In Jong Kim, Mei-Jing Lee, Steven A. Adah, Tyler J. Raymond, Edward J. Bilsky, Mario D. Aceto, Everette L. May, Louis S. Harris, Andrew Coop, Christina M....> ;Organic & Biomolecular Chemistry. 2007 Apr 4
• 12 citations
  DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods.
  Kathleen M. Gilbert, Terrence L. Boos, Christina M. Dersch, Elisabeth Greiner, Arthur E. Jacobson, David B. Lewis, Dorota Matecka, Thomas E. Prisinzano, Ying Zhang, Ri...> ;Bioorganic & Medicinal Chemistry. 2007 Jan 15
• 9 citations
  Structure-activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl...
  Terrence L. Boos, Elisabeth Greiner, W. Jason Calhoun, Thomas E. Prisinzano, Barbara Nightingale, Christina M. Dersch, Richard B. Rothman, Arthur E. Jacobson, Kenner C...> ;Bioorganic & Medicinal Chemistry. 2006 Jun 1
• 2 citations
  A concise method for the preparation of deuterium-labeled cortisone: synthesis of [6,7-2H]cortisone.
  Agnieszka Sulima, Thomas E. Prisinzano, Thomas F. Spande, Jeffrey R. Deschamps, Noel Whittaker, Zeev Hochberg, Arthur E. Jacobson, Kenner C. Rice> ;Steroids. 2005 Oct 1
• 21 citations
  Studies of the biogenic amine transporters. XI. Identification of a 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR12909) analog that alloste...
  Barbara Nightingale, Christina M. Dersch, Terrence L. Boos, Elisabeth Greiner, William J. Calhoun, Arthur E. Jacobson, Kenner C. Rice, Richard B. Rothman> ;The Journal of Pharmacology and Experimental Therapeutics. 2005 Aug 1
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