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13400 E Shea BlvdScottsdale, AZ 85259
Phone+1 480-301-8000
Fax+1 904-483-2313
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Summary
- Carlos E. Vargas, M.D. is a radiation oncologist and the research chair of Mayo Clinic Arizona’s Department of Radiation Oncology. He treats numerous cancers such as bladder, breast, prostate, and testicular using advanced radiation techniques including stereotactic body radiation (SBRT), intensity modulated radiation, image guided radiation, and spot scanned proton therapy. Dr. Vargas earned his medical degree at Pontificia Universidad Javeriana, Bogota, Colombia, and he completed his residency at William Beaumont Hospital in Royal Oak, Michigan. After completion, he headed the Prostate Cancer Program at the University of Florida in Jacksonville. Currently, Dr. Vargas works as an associate professor of radiation oncology at Mayo Clinic College of Medicine and Science. He is the principal investigator in multiple clinical studies for breast, prostate, and bladder cancer; as well as studies addressing questions about the effect of radiation on the cancer and normal tissue. U.S. News & World Report ranks Mayo Clinic Arizona the #1 hospital in the state.
Education & Training
Corewell Health William Beaumont University HospitalResidency, Radiation Oncology, 2001 - 2005
Pontifical Xavierian UniversityClass of 1997
Certifications & Licensure
FL State Medical License 2005 - 2027
AZ State Medical License 2014 - 2026
NM State Medical License 2022 - 2026
NV State Medical License 2022 - 2023
MI State Medical License 2000 - 2008
American Board of Radiology Radiation Oncology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage Stage 1 Certification FirstNet (Clinical), Cerner Corporation, 2016-2017
- CMS Meaningful Use Stage Stage 1 Certification PowerChart (Clinical), Cerner Corporation, 2016-2017
- CMS Meaningful Use Stage Stage 1 Certification Access Profiler Enterprise, EMRConnect, 2016-2017
Clinical Trials
- Hypofractionated Radiation Therapy in Preventing Recurrence in Patients With Breast Cancer After Surgery Start of enrollment: 2018 Feb 07
- Hypofractionated Radiation Therapy in Treating Participants With Breast Cancer Before Surgery Start of enrollment: 2018 Nov 20
- Phase III Study of 5tx vs 15tx of RT (X-rays or Protons) Including RNI in Breast Cancer Patients Start of enrollment: 2020 Jun 16
Publications & Presentations
PubMed
- Comparison of partial breast radiation modalities in women with early-stage breast cancer: a target trial emulation.Dean A Shumway, Kimberly S Corbin, Satomi Shiraishi, Magdoleen H Farah, Farah Fleti
Journal of the National Cancer Institute. 2025-12-06 - Establishing prospective performance monitoring for real-world implementation of deep learning-based auto-segmentation in prostate cancer radiotherapy.Libing Zhu, Yi Rong, Nathan Y Yu, Jason M Holmes, Carlos E Vargas
Physics and Imaging in Radiation Oncology. 2025-10-01 - Clinical Outcomes After Proton Therapy Reirradiation for Recurrent Malignant Glioma: Analysis From the Prospective Proton Collaborative Group Registry.Omer Gal, Stephen Mihalcik, Lia M Halasz, John H Chang, C Jake Wang
Advances in Radiation Oncology. 2025-08-01
Press Mentions
Mayo Clinic Experts Present Key Radiation Oncology Findings at ASTROSeptember 27th, 2025
Prostate Cancer Explained: From Antigen Tests to Treatment OptionsJuly 28th, 2025
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