ChaficKaramMD

PubMed

• Diagnosis and treatment of hereditary transthyretin amyloidosis with polyneuropathy in the United States: Recommendations from a panel of experts.
  Brannagan, T. H., Chafic Karam, Michelle L Mauermann, Alejandra Gonzalez-Duarte, Michelle C Kaku, Senda Ajroud-Driss, Thomas H Brannagan 3rd, Michael Polydefkis> ;Muscle & Nerve. 2024 Mar 1
• Single institution experience with efgartigimod in patients with myasthenia gravis: Patient selection, dosing schedules, treatment response, and adverse events.
  Madeline Singer, Sami Khella, Shawn Bird, Paul McIntosh, Bandhu Paudyal, Anil Wadhwani, Colin Quinn, Chafic Karam> ;Muscle & Nerve. 2024 Jan 1
• 1 citations
  Effect of efgartigimod on muscle group subdomains in participants with generalized myasthenia gravis: post hoc analyses of the phase 3 pivotal ADAPT study.
  Vera Bril, James F Howard Jr, Chafic Karam, Jan L De Bleecker, Hiroyuki Murai, Kimiaki Utsugisawa, Peter Ulrichts, Edward Brauer, Sihui Zhao, Renato Mantegazza, Tuan Vu> ;European Journal of Neurology. 2024 Jan 1
• Pearls & Oy-sters: Case Report of a Patient With Adult-Onset Thymidine Kinase 2 Gene Deficiency.
  Jennifer Morganroth, Lovisa Ljungberg, Amy Goldstein, Staci Kallish, Stephanie B Asher, Colin Quinn, Raymond S Price, Chafic Karam> ;Neurology. 2023 Oct 17
• The impact of inotersen on Neuropathy Impairment Score in patients with hereditary transthyretin amyloidosis with polyneuropathy.
  Aaron Yarlas, Andrew Lovley, Duncan Brown, Montserrat Vera-Llonch, Sami Khella, Chafic Karam> ;BMC Neurology. 2023 Mar 17
• Long-term safety, tolerability, and efficacy of efgartigimod (ADAPT+): interim results from a phase 3 open-label extension study in participants with generalized myast...
  Howard, J., Bril, V., Vu, T., Karam, C., Peric, S., De Bleecker, J., Murai, H., Meisel, A., Beydoun, S., Pasnoor, M., Guglietta, A., Van Hoorick, B., Steeland, S., T'j...> ;Frontiers in Neurology. 2023 Jan 1
• Factors associated with increased health-related quality-of-life benefits in hereditary transthyretin amyloidosis polyneuropathy patients treated with inotersen.
  Chafic Karam, Duncan Brown, Min Yang, Nicolae Done, Ibou Dieye, Ana Bozas, Montserrat Vera Llonch, James Signorovitch> ;Muscle & Nerve. 2022 Sep 1
• Pain, sleep, fatigue, and activities of daily living in patients with neuropathy.
  Chafic Karam> ;Muscle & Nerve. 2022 Oct 1
• 3 citations
  Long-term treatment effects of inotersen on health-related quality of life in patients with hATTR amyloidosis with polyneuropathy: Analysis of the open-label extension...
  Chafic Karam, Duncan Brown, Min Yang, Nicolae Done, Jing Jing Zhu, Alexandra Greatsinger, Ana Bozas, Montserrat Vera-Llonch, James Signorovitch> ;Muscle & Nerve. 2022 Oct 1
• 8 citations
  Randomized phase 2 study of ACE-083, a muscle-promoting agent, in facioscapulohumeral muscular dystrophy.
  Jeffrey M Statland, Craig Campbell, Urvi Desai, Chafic Karam, Jordi Díaz-Manera, Jeffrey T Guptill, Lawrence Korngut, Angela Genge, Rabi N Tawil, Lauren Elman, Nanette...> ;Muscle & Nerve. 2022 Jul 1
• 6 citations
  Randomized Phase 2 Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease.
  Thomas, F., Brannagan, T., Butterfield, R., Desai, U., Habib, A., Herrmann, D., Eichinger, K., Johnson, N., Karam, C., Pestronk, A., Quinn, C., Shy, M., Statland, J., ...> ;Neurology. 2022 Jun 6
• 1 citations
  Chronic Inflammatory Demyelinating Polyradiculoneuropathy: Five New Things.
  Chafic Karam> ;Neurology. Clinical Practice. 2022 Jun 1
• 30 citations
  Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the...
  Sabrina Paganoni, Suzanne Hendrix, Samuel P Dickson, Newman Knowlton, James D Berry, Michael A Elliott, Samuel Maiser, Chafic Karam, James B Caress, Margaret Ayo Owegi...> ;Journal of Neurology, Neurosurgery, and Psychiatry. 2022 May 16
• 7 citations
  Early Data on Long-term Impact of Inotersen on Quality-of-Life in Patients with Hereditary Transthyretin Amyloidosis Polyneuropathy: Open-Label Extension of NEURO-TTR.
  Aaron Yarlas, Andrew Lovley, Kristen L. McCausland, Duncan Brown, Montserrat Vera-Llonch, Isabel Conceição, Chafic Karam, Sami Khella, Laura Obici, Márcia Waddington-Cruz> ;Neurology and Therapy. 2021 Aug 5
• 5 citations
  Subcutaneous immunoglobulin treatment for chronic inflammatory demyelinating polyneuropathy
  Namita Goyal, Chafic Karam, Kazim A. Sheikh, Mazen M. Dimachkie> ;Muscle & Nerve. 2021 Jul 14
• 123 citations
  Safety, efficacy, and tolerability of efgartigimod in patients with generalised myasthenia gravis (ADAPT): a multicentre, randomised, placebo-controlled, phase 3 trial.
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,...> ;The Lancet. Neurology. 2021 Jul 1
• 19 citations
  Long-term efficacy of eculizumab in refractory generalized myasthenia gravis: responder analyses.
  James F. Howard, Chafic Karam, Marcus Yountz, Fanny O'Brien, Tahseen Mozaffar> ;Annals of Clinical and Translational Neurology. 2021 May 27
• 18 citations
  Efficacy and Safety of Bimagrumab in Sporadic Inclusion Body Myositis: Long-term Extension of RESILIENT
  Anthony A. Amato, Michael G. Hanna, Pedro Machado, Umesh A. Badrising, Hector Chinoy, Olivier Benveniste, Ananda Krishna Karanam, Min Wu, Laszlo Tanko, Agnes Annette S...> ;Neurology. 2021 Mar 23
• 3 citations
  CIDP mimics: a case series.
  Orly Moshe-Lilie, Erik Ensrud, Thomas Ragole, Chahin Nizar, Diana Dimitrova, Chafic Karam> ;BMC Neurology. 2021 Feb 28
• 27 citations
  Screening for ATTR amyloidosis in the clinic: overlapping disorders, misdiagnosis, and multiorgan awareness.
  Jose Nativi-Nicolau, Chafic Karam, Sami Khella, Mathew S. Maurer> ;Heart Failure Reviews. 2021 Feb 20
• 10 citations
  Rate of neuropathic progression in hereditary transthyretin amyloidosis with polyneuropathy and other peripheral neuropathies: a systematic review and meta-analysis.
  Xiaochen Lin, Aaron Yarlas, Montserrat Vera-Llonch, Nishtha Baranwal, Josh Biber, Duncan Brown, Braden Vogt, Chafic Karam> ;BMC Neurology. 2021 Feb 12
• Pericardial Tamponade and Other Cardiac Complications in POEMS Syndrome.
  Jacqueline Levene, Nathanial Murray, Sima S. Desai, Timothy F. Simpson, Chafic Karam, Rebecca Silbermann, Ahmad Masri> ;JACC. Case Reports. 2021 Feb 1
• 87 citations
  Long-term survival of participants in the CENTAUR trial of sodium phenylbutyrate-taurursodiol in amyotrophic lateral sclerosis
  Sabrina Paganoni, Suzanne Hendrix, Samuel P. Dickson, Newman Knowlton, Eric A. Macklin, James D. Berry, Michael A. Elliott, Samuel Maiser, Chafic Karam, James B. Cares...> ;Muscle & Nerve. 2021 Jan 1
• 17 citations
  Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS): Bayesian Adaptive Comparative Effectiveness Randomized T...
  Richard J. Barohn, Byron J. Gajewski, Mamatha Pasnoor, Alexandra R. Brown, Laura Herbelin, Kim S. Kimminau, Dinesh Pal Mudaranthakam, Omar Jawdat, Mazen M. Dimachkie, ...> ;JAMA Neurology. 2021 Jan 1
• 10 citations
  Refractory CIDP: Clinical characteristics, antibodies and response to alternative treatment.
  Jamila Godil, Matthew J. Barrett, Erik Ensrud, Nizar Chahin, Chafic Karam> ;Journal of the Neurological Sciences. 2020 Nov 15
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