CharlesHSpencerMD

PubMed

• Treatment escalation patterns to start biologics in refractory moderate juvenile dermatomyositis among members of the Childhood Arthritis and Rheumatology Research All...
  Matthew A Sherman, Hanna Kim, Katelyn Banschbach, Amanda Brown, Harry L Gewanter, Bianca Lang, Megan Perron, Angela Byun Robinson, Jacob Spitznagle, Cory Stingl, Grant...> ;Pediatric Rheumatology Online Journal. 2023 Jan 6
• 1 citations
  Time for change at PROJ in 2021
  Charles H. Spencer, Alberto Martini> ;Pediatric Rheumatology Online Journal. 2021 May 1
• 2 citations
  Biologics in refractory idiopathic inflammatory myositis (IIM): What experience in juvenile vs adult myositis tells us about the use of biologics in pediatric IIM
  Anjali Patwardhan, Charles H. Spencer> ;Modern Rheumatology. 2021 Apr 6
• 17 citations
  An unprecedented COPA gene mutation in two patients in the same family: comparative clinical analysis of newly reported patients with other known COPA gene mutations.
  Anjali Patwardhan, Charles H. Spencer> ;Pediatric Rheumatology Online Journal. 2019 Aug 27
• 7 citations
  Biologics in refractory myositis: experience in juvenile vs. adult myositis; part II: emerging biologic and other therapies on the horizon.
  Anjali Patwardhan, Charles H. Spencer> ;Pediatric Rheumatology Online Journal. 2019 Aug 20
• 7 citations
  Healthcare Use Patterns and Economic Burden of Chronic Musculoskeletal Pain in Children before Diagnosis.
  Frances Tian, Patsy Guittar, Melissa Moore-Clingenpeel, Gloria C. Higgins, Stacy P. Ardoin, Charles H. Spencer, Karla Jones, Bethanne Thomas, Shoghik Akoghlanian, Shar...> ;The Journal of Pediatrics. 2018 Jun 1
• 48 citations
  Age and fecal microbial strain-specific differences in patients with spondyloarthritis
  Pamela F. Weiss, Jennifer E. Weiss, Peter A. Nigrovic, Barbara Edelheit, S. Lou Bridges, Maria I. Danila, Charles H. Spencer, Marilynn Punaro, Kenneth N. Schikler, And...> ;Arthritis Research & Therapy. 2018 Jan 30
• 50 citations
  Assessment of transition readiness in adolescents and young adults with chronic health conditions.
  Paul T. Jensen, Gabrielle V. Paul, Stephanie LaCount, Juan Peng, Charles H. Spencer, Gloria C. Higgins, Brendan Boyle, Manmohan K. Kamboj, Christopher Smallwood, Stacy...> ;Pediatric Rheumatology Online Journal. 2017 Sep 9
• 31 citations
  Biologic therapies for refractory juvenile dermatomyositis: five years of experience of the Childhood Arthritis and Rheumatology Research Alliance in North America
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Pediatric Rheumatology Online Journal. 2017 Jun 13
• 29 citations
  Gene copy-number variations (CNVs) of complement C4 and C4A deficiency in genetic risk and pathogenesis of juvenile dermatomyositis
  Katherine E. Lintner, Anjali Patwardhan, Lisa G. Rider, Rabheh Abdul-Aziz, Yee Ling Wu, Emeli Lundström, Leonid Padyukov, Bi Zhou, Alaaedin Alhomosh, David L. Newsom, ...> ;Annals of the Rheumatic Diseases. 2016 Sep 1
• 15 citations
  Muscle MRI at the time of questionable disease flares in Juvenile Dermatomyositis (JDM).
  Rabheh Abdul-Aziz, Chack-Yung Yu, Brent Adler, Sharon Bout-Tabaku, Katherine E. Lintner, Melissa Moore-Clingenpeel, Charles H. Spencer> ;Pediatric Rheumatology Online Journal. 2017 Apr 12
• 42 citations
  Childhood Arthritis and Rheumatology Research Alliance consensus clinical treatment plans for juvenile dermatomyositis with skin predominant disease
  Susan Kim, Philip Kahn, Angela Byun Robinson, Bianca Lang, Andrew I. Shulman, Edward J Oberle, Kenneth N. Schikler, Megan L. Curran, Lilliana Barillas-Arias, Charles H...> ;Pediatric Rheumatology Online Journal. 2017 Jan 11
• 35 citations
  Childhood Arthritis and Rheumatology Research Alliance Consensus Clinical Treatment Plans for Juvenile Dermatomyositis with Persistent Skin Rash
  Adam M. Huber, Susan Kim, Ann M. Reed, Ruy Carrasco, Brian M. Feldman, Sandy D. Hong, Philip Kahn, Homaira Rahimi, Angela Byun Robinson, Richard K. Vehe, Jennifer E. W...> ;The Journal of Rheumatology. 2017 Jan 1
• 14 citations
  High Levels of Decisional Conflict and Decision Regret When Making Decisions About Biologics.
  Ellen A. Lipstein, Daniel J. Lovell, Lee A. Denson, Sandra C. Kim, Charles H. Spencer, Richard F. Ittenbach, Maria T. Britto> ;Journal of Pediatric Gastroenterology and Nutrition. 2016 Dec 1
• 7 citations
  Parents’ information needs and influential factors when making decisions about TNF-α inhibitors
  Ellen A. Lipstein, Daniel J. Lovell, Lee A. Denson, Sandra C. Kim, Charles H. Spencer, Maria T. Britto> ;Pediatric Rheumatology Online Journal. 2016 Sep 15
• 42 citations
  Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in E...
  Ji Yih Chen, Yee Ling Wu, Mo Yin Mok, Yeong-Jian Jan Wu, Katherine E. Lintner, Chin-Man Wang, Erwin K. Chung, Yan Yang, Bi Zhou, Huanyu Wang, Denise J. H. C. Yu, Alaae...> ;Arthritis & Rheumatology. 2016 Jun 1
• 115 citations
  Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases.
  Katherine E. Lintner, Yee Ling Wu, Yan Yang, Charles H. Spencer, Georges Hauptmann, Lee A. Hebert, John P. Atkinson, C. Yung Yu> ;Frontiers in Immunology. 2016 Feb 15
• 4 citations
  Pediatric Rheumatology for the Primary Care Clinicians-Recognizing Patterns of Disease.
  Charles H. Spencer, Anjali Patwardhan> ;Current Problems in Pediatric and Adolescent Health Care. 2015 Jul 1
• 46 citations
  Quantitative evaluation of a pediatric rheumatology transition program.
  Paul T. Jensen, Jill Karnes, Karla Jones, Amy Lehman, Robert M. Rennebohm, Gloria C. Higgins, Charles H. Spencer, Stacy P. Ardoin> ;Pediatric Rheumatology Online Journal. 2015 May 24
• 10 citations
  Current pediatric rheumatology fellowship training in the United States: what fellows actually do
  Anjali Patwardhan, Michael Henrickson, Laura Laskosz, Sandy DuyenHong, Charles H. Spencer> ;Pediatric Rheumatology Online Journal. 2014 Feb 10
• Notice of redundant publication: Aerobic capacity and disease activity in children, adolescents and young adults with juvenile idiopathic arthritis (JIA).
  Alberto Martini, Charles H. Spencer> ;Pediatric Rheumatology Online Journal. 2013 Jan 14
• 22 citations
  Is juvenile dermatomyositis a different disease in children up to three years of age at onset than in children above three years at onset? A retrospective review of 23...
  Anjali Patwardhan, Robert M. Rennebohm, Igor Dvorchik, Charles H. Spencer> ;Pediatric Rheumatology Online Journal. 2012 Sep 20
• 1 citations
  The growth of Pediatric Rheumatology: Pediatric Rheumatology European Society and the impact factor
  Charles H. Spencer, Alberto Martini> ;Pediatric Rheumatology Online Journal. 2012 Jul 24
• 32 citations
  Review for the generalist: The antinuclear antibody test in children - When to use it and what to do with a positive titer
  Peter N. Malleson, Murray J. Mackinnon, Michaela Sailer-Hoeck, Charles H. Spencer> ;Pediatric Rheumatology Online Journal. 2010 Oct 20
• 44 citations
  Joint contractures in the absence of inflammation may indicate mucopolysaccharidosis
  Rolando Cimaz, Giovanni Valentino Coppa, Isabelle Koné-Paut, Bianca Link, Gregory M. Pastores, Maria Jesus Rua Elorduy, Charles H. Spencer, Carter Thorne, Nico M Wulff...> ;Pediatric Rheumatology Online Journal. 2009 Oct 23
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Journal Articles

• Quantitative Evaluation of a Pediatric Rheumatology Transition Program  
  Stacy P Ardoin, Paul T Jensen, Robert Rennebohm, Gloria C Higgins, Charles H Spencer, BioMed Central
• Review for the Generalist: the antinuclear antibody test in children – when to use it and what to do with a positive titer.  
  Malleson PN, MacKinnon Murray J, Sailer-Hoeck Michaela, Spencer, Charles H, PROJ 2010; 8:27
• Are patient surveys valuable as a service-improvement Tool in health services.  
  Patwardhan A, Spencer CH, An overview Journal of Healthcare Leadership 2012:4 1-14
• Bone and Joint Infections.  
  Spencer, C, Cur Opin Rheum, 10: 494-497
• Hip disease in children with JRA.  
  Spencer C, Bernstein B, Cur Opin Rheum
• Immunogenetic studies in juvenile dermatomyositis: HLA-DR antigen frequencies.  
  Freidman, J., Pachman, L., Spencer, C, Arthritis Rheum. 2:45
• Immunogenetic studies of juvenile dermatomyositis.  
  Friedman, J., Pachman, L., Spencer, C., Sullivan, D, Tissue Antigens 21:45
• The course of treated juvenile dermatomyositis.  
  Spencer, C., Hanson, V., Singsen, B., Bernstein, B., Kornreich, H., King,K, J. Pediatr 105:399
• Immunogenetic studies juvenile dermatomyositis: III Study of antibody to organ - specific and nuclear antigens.  
  Pachman, L., Friedman J., Marjowski, M., Jonasson, O., Radvang, R., Sharp, G., Cobb, M., Battles, N., Crowe, W., Fink, C., Hanson, V., Levinson, J., Spencer, C., Sull..., Arthritis Rheum. 28, 2:151
• Fusobacterium Necrophorum sepsis with cerebral infarction.  
  Spencer, C., Slusher, C.W., Sanders C.V., and Aldridge, K.E, South Med J 82,8:1040
• Maternal antibodies to SSA/RO are associated with early onset of disease and male sex among children with systemic lupus erythematosus.  
  Lehman, T.J., Harley, J.B., Santner, T.N., Silverman, E., Petty, R., Spencer, C., Reichlin, M, Arthritis Rheum. 32:1414-1420
• Auranofin in the treatment of juvenile rheumatoid arthritis.  
  Giannini, E., Spencer, C. et al, Arthritis Rheum. 33:466- 476
• Ibuprofen suspension in the treatment of juvenile Rheumatoid arthritis.  
  Giannini, E.H., Spencer, and C. et al, J. Pediatr. Vol. 4 117: 645-652
• School attendance and patterns, special services and special needs in pediatric patients with rheumatoid diseases - Results of a multicenter study.  
  Lovell, D., Spencer, C. et al, Arthritis Care and Research Vol. 3:4, 196-203
• Auranofin Therapy for Juvenile Rheumatoid Arthritis: Results of the Five-Year Open Label Extension Trial.  
  Giannini, E.H., Barron, K.S., Spencer, C.H., Person, D.A., Baum, J., et al, Journal of Rheumatology, 18:8,1240-1242
• Methotrexate in resistant juvenile rheumatoid arthritis.  
  Giannini, E., Spencer, C., et al, NEJM 326: 10-15
• The T cell receptor in autoimmune disease.  
  Bluestone J.A, Spencer, C., Hirsch, R, J . Rheumatol 19 (Suppl 33) 75-77
• Effects of methotrexate on radiographic progression in juvenile rheumatoid arthritis.  
  Harel, L.,Wagner-Weiner, L., Poznanski, A., Spencer, C., Ekwo, E., Magilavy, D, Arthritis Rheum. 10:1370-1374
• The role of gamma delta T cell receptor cells in murine collagen induced arthritis.  
  Peterman, G., Spencer, C., Sperling Al, Bluestone, J, J Immunol 151:6546-6558
• FOPE II and Pediatric Subspecialists- Commentary.  
  Gilchrist G, Fierson W, Spencer C, and et al, Pediatrics 107 (5):1179-1180
• Treatment of refractory renal disease in pediatric onset systemic lupus erythematosus of childhood.  
  Buratti S, Szer I, Spencer C, Reiff A, J Rheum 2001, 2:244-49
• Martini A Mission of PROJ.  
  Spencer C, Pediatric Rheumatology Online Journal (1): 1-2
• Health status of patients with juvenile rheumatoid arthritis at 1 and 5 years after diagnosis.  
  Bowyer SL, Roettcher PA, Higgins GC, Spencer C, J Rheum; 30(2): 394-400
• Assessment of Damage in Juvenile Systemic Lupus Erythematosus: A Multicenter Cohort Study.  
  Ravelli A, Duarte-Salazar R, Baretti S, Spencer C, Bernstein B, et al, Arthritis Rheum (Arthritis Care and Research) ;49 (4):501-7
• Treatment of SLE in children and adolescents in 2003: Is it better to have leukemia.  
  Spencer, CH, Ped Rheum Online J 2003 Jan-Feb;1(1):7-12
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Books/Book Chapters

• Chronic Disorders in Adolescence. 
  Chapter: Chronic arthritis disease in adolescence 
  Spencer, C., Bernstein, BEditors: Smith, M.PSG Publishing, Boston
• Current Therapy. 
  Chapter: Juvenile rheumatoid arthritis 
  Page 907 - 911Spencer and CEditors: Rachel, RE.W.B. Saunders, PhiladelphiaEdition 9,
• The School Experience of Children with Arthritis: Coping at School in the 1990's and transition into adulthood. 
  Page 1258 - 1297Spencer, C., Fife, R., Rabinovich, EPed Clin N America
• Musculoskeletal pain syndromes in Adolescent Health Care-A Practical Guide. 
  Bernstein B and Spencer C
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Abstracts/Posters

• Muscle involvement in Localized Scleroderma of Childhood.
  Spencer, C., Isaacs, H., Kornreich, H., Bernstein, B., Singsen, B., Neustein, H., and Hanson, V, Clinical Research 185B
• Three courses of juvenile dermatomyositis.
  Spencer, C., Kornreich, H., Bernstein, B., King, K., Singsen, B., and Hanson, and V, Arthritis Rheum. 22 6:661
• Circulating immune complexes in juvenile dermatomyositis.
  Spencer, C., Hanson, V., Singsen, B., Bernstein, B., Kornreich, H., and King, K, Arthritis Rheum. 23, 6:701
• Nucleolar antihistones (H) antibodies (Ab) in juvenile dermatomyositis.
  Arroyave, C., Packman, L., Rich, K., Passo, M., Kaine, J., Spencer, C., Nickeson, Jr., R, Arthritis Rheum. 28:4, S25
• Suppressor Inducer (SI) and Helper Inducer (HI) T cell subsets in juvenile rheumatoid arthritis.
  Spencer, C.H., Michalski, J., and Gaumer, R, Arthritis Rheum. 29, 4 (suppl.):S66
• Meeting the Needs of Students with Juvenile Rheumatoid Arthritis in a SNAAP (School Nurse Arthritis Advocacy Program).
  Liburd, N., Spencer, C., Edwards, J, American Rheumatism Association, 51st Annual Meeting, June 9-13, Washington, DC
• The use of medication information sheets in a pediatric rheumatology education program.
  Liburd, N., Spencer, C., Edwards, J, American Rheumatism Association, 51st Annual Meeting, June 9-13, Washington, DC
• Oral Gold (Auranofin, AU) in juvenile rheumatoid arthritis: Results of the double-blind, Placebo (P) Controlled Trial.
  Brewer, E., Giannini, E., Bernstein, B., Person, D., Fink, C., Athreya, B., Jacobs, J., Kredich, D., Spencer, C., Baum, J., Passo, M, Arthritis Rheum. 31, 4 (suppl.); 526
• Mapping of transcription regulatory elements in the interleukin-2 receptor alpha chain.
  Cross, S., Wolf, J., Halden, N., Spencer, C., Leonard, W.J, J. Cell Biochem. 12D:180
• Mapping of 5' transcriptional regulatory elements of the interleukin-2 receptor alpha chain.
  Cross, S.L., Wolf, J.B., Halden, N.F., Spencer, C.H., Leonard, W.J, Clinical Research 36, no. 3:403
• Vivo administration of anti-CD3 monoclonal antibody for the treatment of collagen-induced arthritis in DBA-1 mice.
  Spencer, C., Peterman, G., Hirsch R., Bluestone, and J, Arthritis Rheum Vol 33:10, C78
• Intravenous Pulse Cyclophosphamide Therapy (IVCY) for Childhood Lupus Nephritis: Variable Renal Outcomes at Three to Six Year Followups.
  Wagner-Weiner, L., Emery, H., Spencer, C.H., Sisung, C, Magilavy, D.B, Arthritis and Rheumatism. Vol 33:10, C77
• Intravenous Pulse Cyclophasphamide Therapy (IVCY) for Childhood Lupus Nephritis: Variable Renal Outcomes at Three to Six Year Followups.
  Wagner-Weiner, L., Emery, H., Spencer, C.H., Sisung, C., Magilavy, D.B, J. Rheum Vol 33:620
• The role of T cells in L. casei-induced coronary arteritis.
  Spencer, C., Hirsch, R., Bluestone, J, Arthritis Rheum. Vol. 34, pC120
• Immunotherapy of collagen-induced arthritis in DBA-1 mice: Contrasting effects of monoclonal antibodies (mAb's) to alpha-beta or gamma-delta T cell receptors.
  Spencer, C. Peterman, G., Bluestone, J, Arthritis Rheum 36, 9 (supplement), S267
• The clinical response of children with JRA on long-term methotrexate therapy.
  Spencer, C. Wagner-Weiner, L. Rabinovich, CE, Arthritis Rheum 38(9), S283
• The role of T cells and macrophages in the coronary arteritis of a murine model which resembles Kawasaki Syndrome.
  Spencer, C. Lehman TJ, Koons, A., Hirsch R, Barrett T, Arthritis Rheum 39, 9(supplement) S290
• Osteoporosis in Juvenile Rheumatoid Arthritis.
  Rabinovich C.E., Wagner-Weiner L., Weuller, J., Spencer, C, Arthritis Rheum 40: S323
• Response of Refractory JRA Patients to Cyclosporine A Therapy.
  Yerolan, O., Rabinovich, E., Wagner-Weiner, L., Spencer, CH, Arthritis Rheum 40: S47
• HLA DRB1, DQA1, DQB1, and DPB1 alleles in children with juvenile arthritis in three ethnic groups.
  Reveille J.D., Spencer, C.H., Rivas Chacon, R.F., Myones, B, Arthritis Rheum 40: S241
• Prognostic Indicators for Children with Juvenile Arthritis on Long Term Methotrexate Therapy.
  Spencer C., Jones, O., Wagner-Weiner, L., Rabinovich, E, Rev Rheum 64: 245S
• Functional status of children with JRA who were diagnosed and treated by pediatric rheumatologists.
  Bowyer S, Roettcher P, Schikler K, Spencer C, et al, Arthritis Rheum 41, S95
• The short-term safety and efficacy of mycofenolate (Cellcept) in treatment of children with pediatric rheumatic diseases.
  Spencer C, Hickey K, Bartosh S, Arthritis Rheum 42, S48
• The occurrence and course of Epstein-Barr virus infection in childhood lupus.
  Wagner-Weiner L, Spencer C, Rabinovich E, Katz B, Arthritis Rheum 42: S392
• The effects of proteosome inhibitor, MG 115, on FAS mediated aptosis of murine cell lines.
  Yeralan O, Wu T, Spencer C, Argon Y, Arthritis Rheum 42, S264
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Lectures

• The musculoskeletal exam in Pediatric Rheumatology. 
  Park City Meeting V of Pediatric Rheumatology Keystone, CO
• The clinical course of treated juvenile dermatomyositis. 
  American Rheumatism Association National Meeting
• Immune complexes in the sera of patients with juvenile dermatomyositis. 
  American Rheumatism Association National Meeting
• Immunotherapy of collagen-induced arthritis in DBA-1mice: Contrasting effects of monoclonal antibodies to alpha-beta and gamma delta T cells receptors. 
  American College of Rheumatology meeting
• The differentiation of acute leukemia from juvenile idiopathic arthritis. 
  Congress of the Pediatric Rheumatology European Society (PReS)
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