ChristopherLarsonMD

PubMed

• 5 citations
  ROCKET: Phase II Randomized, Active-controlled, Multicenter Trial to Assess the Safety and Efficacy of RRx-001 + Irinotecan vs. Single-agent Regorafenib in Third/Fourt...
  Tony R Reid, Nacer Abrouk, Scott Caroen, Bryan Oronsky, Meaghan Stirn, Christopher Larson, Keola Beale, Susan J Knox, George Fisher> ;Clinical Colorectal Cancer. 2023 Mar 1
• 6 citations
  BETA PRIME: Phase I study of AdAPT-001 as monotherapy and combined with a checkpoint inhibitor in superficially accessible, treatment-refractory solid tumors.
  Santosh Kesari, Alberto Bessudo, Brian R Gastman, Anthony P Conley, Victoria M Villaflor, Lisle M Nabell, DeLisa Madere, Emma Chacon, Christina Spencer, Li Li, Christo...> ;Future Oncology. 2022 Sep 1
• 7 citations
  AdAPT-001, an oncolytic adenovirus armed with a TGF-β trap, overcomesresistance to PD-L1-immunotherapy.
  Christopher Larson, Bryan Oronsky, Tony Reid> ;American Journal of Cancer Research. 2022 Jan 1
• 157 citations
  A Review of Persistent Post-COVID Syndrome (PPCS).
  Bryan T. Oronsky, Christopher A. Larson, Terese C. Hammond, Arnold L. Oronsky, Santosh Kesari, Michelle Lybeck, Tony R. Reid> ;Clinical Reviews in Allergy & Immunology. 2021 Feb 20
• 8 citations
  Toxicology and biodistribution of AdAPT-001, a replication-competent type 5 adenovirus with a trap for the immunosuppressive cytokine, TGF-beta.
  Christopher Larson, Bryan Oronsky, Nacer E Abrouk, Arnold L. Oronsky, Tony R. Reid> ;American Journal of Cancer Research. 2021 Jan 1
• 5 citations
  COVID-19 and cancer: A guide with suggested COVID-19 rule-out criteria to support clinical decision-making.
  Christopher Larson, Bryan Oronsky, Sharad Goyal, Carolyn M. Ray, Farah Hedjran, Terese C. Hammond, Santosh Kesari, Scott Caroen, Michelle Lybeck, Vaughn E. Dobalian, A...> ;Biochimica Et Biophysica Acta. Reviews on Cancer. 2020 Aug 20
• 90 citations
  TGF-beta: a master immune regulator.
  Christopher A. Larson, Bryan Oronsky, Corey A. Carter, Arnold L. Oronsky, Susan J. Knox, David J. Sher, Tony R. Reid> ;Expert Opinion on Therapeutic Targets. 2020 Apr 12
• 43 citations
  Locally advanced rectal cancer: The past, present, and future.
  Bryan Oronsky, Tony R. Reid, Christopher A. Larson, Susan J. Knox> ;Seminars in Oncology. 2020 Feb 21
• 36 citations
  REPLATINUM Phase III randomized study: RRx-001 + platinum doublet versus platinum doublet in third-line small cell lung cancer.
  Bryan Oronsky, Tony R. Reid, Christopher A. Larson, Scott Caroen, Mary Flanagan Quinn, Erica Burbano, Gina Varner, Bennett Thilagar, Bradley Brown, Angelique Coyle, Li...> ;Future Oncology. 2019 Sep 11
• CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice.
  Riopel, M.,Vassallo, M.,Ehinger, E.,Pattison, J.,Bowden, K.,Winkels, H.,Wilson, M.,de Jong, R.,Patel, S.,Balakrishna, D.,Bilakovics, J.,Fanjul, A.,Plonowski, A.,Larson...> ;Mol Metab. 2018 Dec 17
• 6 citations
  A practical guide to the handling and administration of personalized transcriptionally attenuated oncolytic adenoviruses (PTAVs).
  Christopher A. Larson, Bryan Oronsky, Gina Varner, Scott Caroen, Erica Burbano, Elisa Insel, Farah Hedjran, Corey A. Carter, Tony R. Reid> ;Oncoimmunology. 2018 Jul 23
• 16 citations
  RRx-001 protects against cisplatin-induced toxicities
  Bryan Oronsky, Tony R. Reid, Christopher A. Larson, Corey A. Carter, Christina Brzezniak, Arnold L. Oronsky, Pedro Cabrales> ;Journal of Cancer Research and Clinical Oncology. 2017 Apr 17
• 7 citations
  A Partial Response to Reintroduced Chemotherapy in a Resistant Small Cell Lung Cancer Patient after Priming with RRx-001
  Bryan Oronsky, Scott Caroen, Karen Zeman, Mary Flanagan Quinn, Christina Brzezniak, Jan Scicinski, Pedro Cabrales, Tony R. Reid, Jane B. Trepel, Nacer Abrouk, Christop...> ;Clinical Medicine Insights. Oncology. 2016 Nov 6
• 3 citations
  Conversion of Platinum-Etoposide-Resistant to Sensitive SCLC after Treatment with the Epi-Immunotherapeutic RRx-001: A Case Report
  Christina Brzezniak, Bryan Oronsky, Jan Scicinski, Scott Caroen, Pedro Cabrales, Nacer Abrouk, Michelle M. Kim, James F. Brown, Tony R. Reid, Christopher A. Larson, Ar...> ;Oncology Research and Treatment. 2016 Nov 1
• 8 citations
  Turning on the Radio: Epigenetic Inhibitors as Potential Radiopriming Agents
  Bryan Oronsky, Jan Scicinski, Michelle M. Kim, Pedro Cabrales, Michael Salacz, Corey A. Carter, Neil Oronsky, H. Lybeck, Michelle Lybeck, Christopher A. Larson, Tony R...> ;Biomolecules. 2016 Jul 4
• 94 citations
  Going viral: a review of replication-selective oncolytic adenoviruses
  Christopher A. Larson, Bryan Oronsky, Jan Scicinski, Gary Fanger, Meaghan Stirn, Arnold L. Oronsky, Tony R. Reid> ;Oncotarget. 2015 Aug 9
• 23 citations
  A novel immunocompetent murine model for replicating oncolytic adenoviral therapy
  Lingzhi Zhang, Farah Hedjran, Christopher A. Larson, G L Perez, Tony R. Reid> ;Cancer Gene Therapy. 2015 Jan 1
• 15 citations
  Molecular modulation of the copper and cisplatin transport function of CTR1 and its interaction with IRS-4.
  Cheng-Yu Tsai, Christopher A. Larson, Roohangiz Safaei, Stephen B. Howell> ;Biochemical Pharmacology. 2014 Aug 15
• 5 citations
  Targeting tumors using nanoparticle platforms: a phase I study of a systemically administered gene therapy system.
  Christopher A. Larson, Natalie Mendez, Tony R. Reid> ;Molecular Therapy. 2013 May 1
• 14 citations
  Sec61β Controls Sensitivity to Platinum-Containing Chemotherapeutic Agents through Modulation of the Copper-Transporting ATPase ATP7A
  Paolo Abada, Christopher A. Larson, Gerald Manorek, Preston L. Adams, Stephen B. Howell> ;Molecular Pharmacology. 2012 Sep 1
• 34 citations
  An all-atom model of the structure of human copper transporter 1.
  Igor F. Tsigelny, Yuriy Sharikov, Jerry P. Greenberg, Mark A. Miller, Valentina L. Kouznetsova, Christopher A. Larson, Stephen B. Howell> ;Cell Biochemistry and Biophysics. 2012 May 9
• 50 citations
  Copper transporter 2 regulates endocytosis and controls tumor growth and sensitivity to cisplatin in vivo.
  Brian G. Blair, Christopher A. Larson, Preston L. Adams, Paolo Abada, Catherine E. Pesce, Roohangiz Safaei, Stephen B. Howell> ;Molecular Pharmacology. 2011 Jan 1
• 44 citations
  The role of the N-terminus of mammalian copper transporter 1 in the cellular accumulation of cisplatin
  Christopher A. Larson, Preston L. Adams, Danielle D. Jandial, Brian G. Blair, Roohangiz Safaei, Stephen B. Howell> ;Biochemical Pharmacology. 2010 Aug 15
• 33 citations
  The role of the methionines and histidines in the transmembrane domain of mammalian copper transporter 1 in the cellular accumulation of cisplatin.
  Christopher A. Larson, Preston L. Adams, Brian G. Blair, Roohangiz Safaei, Stephen B. Howell> ;Molecular Pharmacology. 2010 Jun 2
• 243 citations
  Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs
  Stephen B. Howell, Roohangiz Safaei, Christopher A. Larson, Michael J. Sailor> ;Molecular Pharmacology. 2010 Jun 1
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