ClaudeSportesMD

Pediatric Hematology & Oncology • Augusta, GA

Staff Clinician, Experimental Transplantation & Immunology Branch; Center for Cancer Research , National Cancer Institute

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Office
1120 15th St
Baa 5407
Augusta, GA 30912
Phone+1 301-435-5280

Fax+1 301-402-7515
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Education & Training

University of Michigan Health SystemFellowship, Pediatric Hematology/Oncology, 1984 - 1986
University of Michigan Health SystemResidency, Pediatrics, 1982 - 1984
University of Michigan Health SystemInternship, Transitional Year, 1979 - 1980
Pierre and Marie Curie University Class of 1979

Certifications & Licensure

TN State Medical License 2019 - 2025
GA State Medical License 2014 - 2021
MD State Medical License 1988 - 2014
American Board of Pediatrics Pediatrics

Clinical Trials

Radiolabeled Monoclonal Antibody Followed by Peripheral Stem Cell Transplantation in Treating Patients With Relapsed or Metastatic Breast Cancer Start of enrollment: 2001 Feb 01
Completed
Phase 1
Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation Start of enrollment: 2003 Mar 01
Completed
Not Applicable
Interleukin-7 in Treating Patients With Refractory Solid Tumors Start of enrollment: 2003 Apr 01
Completed
Phase 1
Th1/Tc1 Immunotherapy Following Stem Cell Transplantation in Multiple Myeloma Start of enrollment: 2010 Nov 10
Terminated
Phase 1, Phase 2
Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy Start of enrollment: 2011 Apr 01
Terminated
Phase 2
Carfilzomib and Stem Cell Transplant for Plasma Cell Myeloma Start of enrollment: 2012 Jul 01
Terminated
Phase 1, Phase 2
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Publications & Presentations

PubMed

5 citations
90Y-Daclizumab (Anti-CD25), High-Dose Carmustine, Etoposide, Cytarabine, and Melphalan Chemotherapy and Autologous Hematopoietic Stem Cell Transplant Yielded Sustained...
Kevin C. Conlon, Claude Sportes, Martin W. Brechbiel, Daniel H. Fowler, Ronald E. Gress, Milos D. Miljkovic, Clara C. Chen, Millie Whatley, Bonita R. Bryant, Erin M Co...> ;Cancer Biotherapy & Radiopharmaceuticals. 2020 May 13
29 citations
Randomized, Placebo-Controlled, Phase III Trial of Fosaprepitant, Ondansetron, Dexamethasone (FOND) Versus FOND Plus Olanzapine (FOND-O) for the Prevention of Chemothe...
Amber B. Clemmons, Julianne Orr, Benjamin Andrick, Arpita Gandhi, Claude Sportes, David L. DeRemer> ;Biology of Blood and Marrow Transplantation. 2018 Oct 1
11 citations
Combination therapy with carfilzomib, lenalidomide and dexamethasone (KRd) results in an unprecedented purity of the stem cell graft in newly diagnosed patients with m...
Nishant Tageja, Neha Korde, Dickran Kazandjian, Sandhya R. Panch, Elisabet E. Manasanch, Manisha Bhutani, Mary Kwok, Sham Mailankody, Constance M. Yuan, Maryalice Stet...> ;Bone Marrow Transplantation. 2018 May 4
3 citations
Prolonged versus short infusion rates for intravenous magnesium sulfate administration in hematopoietic cell transplant patients.
Pam M. Ku, Jennifer L. Waller, Claude Sportes, Amber B. Clemmons> ;Supportive Care in Cancer. 2018 Mar 5
8 citations
High-Dose Sirolimus and Immune-Selective Pentostatin plus Cyclophosphamide Conditioning Yields Stable Mixed Chimerism and Insufficient Graft-versus-Tumor Responses.
Miriam E. Mossoba, David Halverson, Roger Kurlander, Bazetta Blacklock Schuver, Ashley Carpenter, Brenna Hansen, Seth M. Steinberg, Syed Abbas Ali, Nishant Tageja, Fra...> ;Clinical Cancer Research. 2015 Jun 12
443 citations
Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation.
James N. Kochenderfer, Mark E. Dudley, Robert O. Carpenter, Sadik H. Kassim, Jeremy J. Rose, William G. Telford, Frances T. Hakim, David Halverson, Daniel H. Fowler, N...> ;Blood. 2013 Dec 12
3 citations
Host Lymphocyte Depletion as a Strategy to Facilitate Early Full Donor Chimerism after Reduced-Intensity Allogeneic Stem Cell Transplantation
Rachel B. Salit, Daniel H. Fowler, Robert M. Dean, Steven Z. Pavletic, Frances T. Hakim, Seth M. Steinberg, Nancy T. Hardy, Claude Sportes, Ronald E. Gress, Michael R....> ;Biology of Blood and Marrow Transplantation. 2013 Oct 1
23 citations
Phase 2 clinical trial of rapamycin-resistant donor CD4+ Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation.
Daniel H. Fowler, Miriam E. Mossoba, Seth M. Steinberg, David Halverson, David F. Stroncek, Hahn Khuu, Frances T. Hakim, Luciano Castiello, Marianna Sabatino, Susan F....> ;Blood. 2013 Apr 11
72 citations
National Institutes of Health Chronic Graft-versus-Host Disease Staging in Severely Affected Patients: Organ and Global Scoring Correlate with Established Indicators o...
Kristin Baird, Seth M. Steinberg, Lana Grković, Drazen Pulanic, Edward W. Cowen, Sandra A. Mitchell, Kirsten M. Williams, Manuel B. Datiles, Rachel Bishop, Carol W. Ba...> ;Biology of Blood and Marrow Transplantation. 2013 Apr 1
11 citations
Neoantigen and tumor antigen-specific immunity transferred from immunized donors is detectable early after allogeneic transplantation in myeloma patients
Myriam Foglietta, Sattva S. Neelapu, Larry W. Kwak, YingJun Jiang, Durgha Nattamai, Seung Tae Lee, Daniel H. Fowler, Claude Sportes, Ronald E. Gress, Seth M. Steinberg...> ;Bone Marrow Transplantation. 2013 Feb 1
17 citations
Quantitative analysis of T cell receptor diversity in clinical samples of human peripheral blood
Sarfraz Memon, Claude Sportes, Francis A. Flomerfelt, Ronald E. Gress, Frances T. Hakim> ;Journal of Immunological Methods. 2012 Jan 31
9 citations
Phase I trial of adoptive cell transfer with mixed-profile type-I/type-II allogeneic T cells for metastatic breast cancer.
Nancy M. Hardy, Miriam E. Mossoba, Seth M. Steinberg, Vicki Fellowes, Xiao-Yi Yan, Frances T. Hakim, Rebecca Babb, Daniele Avila, Juan Gea-Banacloche, Claude Sportes, ...> ;Clinical Cancer Research. 2011 Nov 1
189 citations
Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States
Jeffrey I. Cohen, Elaine S. Jaffe, Janet K. Dale, Stefania Pittaluga, Helen E. Heslop, Cliona M. Rooney, Stephen Gottschalk, Catherine M. Bollard, V. Koneti Rao, Adria...> ;Blood. 2011 Jun 2
9 citations
Correlation of pretransplant and early post-transplant response assessment with outcomes after reduced-intensity allogeneic hematopoietic stem cell transplantation for...
Michael R. Bishop, Robert M. Dean, Seth M. Steinberg, Jeanne Odom, Seth M. Pollack, Steven Z. Pavletic, Claude Sportes, Ronald E. Gress, Daniel H. Fowler> ;Cancer. 2010 Feb 15
157 citations
Phase I Study of Recombinant Human Interleukin-7 Administration in Subjects with Refractory Malignancy
Claude Sportes, Rebecca Babb, Michael Krumlauf, Frances T. Hakim, Seth M. Steinberg, Catherine Chow, Margaret R. Brown, Thomas A. Fleisher, Pierre Noel, Irina Maric, M...> ;Clinical Cancer Research. 2010 Jan 15
15 citations
Perspective on Potential Clinical Applications of Recombinant Human Interleukin-7
Claude Sportes, Ronald E. Gress, Crystal L. Mackall> ;Annals of the New York Academy of Sciences. 2009 Dec 1
7 citations
Strategies to Improve Long-Term Outcome in Stage IIIB Inflammatory Breast Cancer: Multimodality Treatment Including Dose-Intensive Induction and High-Dose Chemotherapy
Claude Sportes, Seth M. Steinberg, David J. Liewehr, Juan Gea-Banacloche, David N. Danforth, Daniele Avila, Kelly Bryant, Michael Krumlauf, Daniel H. Fowler, Steven Z....> ;Biology of Blood and Marrow Transplantation. 2009 Aug 1
53 citations
Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation
Michael R. Bishop, Robert M. Dean, Seth M. Steinberg, Jeanne Odom, Steven Z. Pavletic, Catherine Chow, Stefania Pittaluga, Claude Sportes, Nancy M. Hardy, Juan Gea-Ban...> ;Annals of Oncology. 2008 Nov 1
365 citations
Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets
Claude Sportes, Frances T. Hakim, Sarfraz Memon, Hua Zhang, Kevin S. Chua, Margaret R. Brown, Thomas A. Fleisher, Michael Krumlauf, Rebecca Babb, Catherine Chow, Terry...> ;The Journal of Experimental Medicine. 2008 Jul 7
23 citations
Oral Mucositis-Related Oropharyngeal Pain and Correlative Tumor Necrosis Factor-α Expression in Adult Oncology Patients Undergoing Hematopoietic Stem Cell Transplantation
Jane M. FalI-Dickson, Edward S. Ramsay, Kathleen Castro, Patricia C. Woltz, Claude Sportes> ;Clinical Therapeutics. 2007 Jan 1
21 citations
Interleukin-7 immunotherapy.
Claude Sportes, Ronald E. Gress> ;Advances in Experimental Medicine and Biology. 2007 Jan 1
42 citations
Phase I clinical trial of costimulated, IL-4 polarized donor CD4+ T cells as augmentation of allogeneic hematopoietic cell transplantation.
Daniel H. Fowler, Jeanne Odom, Seth M. Steinberg, Catherine Chow, Jason Foley, Yelena Kogan, Jeannie Hou, Juan Gea-Banacloche, Claude Sportes, Steven Z. Pavletic, Susa...> ;Biology of Blood and Marrow Transplantation. 2006 Nov 1
325 citations
IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells.
Steven A. Rosenberg, Claude Sportes, Mojgan Ahmadzadeh, Terry J. Fry, Lien T. Ngo, Susan L. Schwarz, Maryalice Stetler-Stevenson, Kathleen E. Morton, Sharon Mavroukaki...> ;Journal of Immunotherapy. 2006 May 1
15 citations
Establishing a platform for immunotherapy: clinical outcome and study of immune reconstitution after high-dose chemotherapy with progenitor cell support in breast canc...
Claude Sportes, Nicole J. McCarthy, Frances T. Hakim, Seth M. Steinberg, David J. Liewehr, David E. Weng, Shivaani Kummar, Juan Gea-Banacloche, Catherine Chow, Robert ...> ;Biology of Blood and Marrow Transplantation. 2005 Jun 1
6 citations
Therapy-related myelodysplastic syndrome (t-MDS) in a patient with anaplastic astrocytoma : Successful treatment with allogeneic bone marrow transplant
Lisa R. Rogers, Nalini Janakiraman, Claude Kasten-Sportes, Mark L. Rosenblum> ;Journal of Neuro-Oncology. 2001 May 1
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Professional Memberships

American Society of Hematology - ASH
Member

Other Languages

French

Hospital Affiliations

WellStar MCG Health, affiliated with Medical College of GeorgiaAugusta, Georgia