ClayB.MarshMD

Internal Medicine • Columbus, OH

Critical Care Medicine, Pulmonology

Professor of Medicine, Ohio State University

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Office
2050 Kenny Rd
Suite 2200
Columbus, OH 43221
Phone+1 614-293-4925

Fax+1 614-293-5503
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Education & Training

Ohio State University HospitalFellowship, Pulmonary Disease and Critical Care Medicine, 1988 - 1992
Ohio State University HospitalResidency, Internal Medicine, 1985 - 1988
West Virginia University School of MedicineClass of 1985

Certifications & Licensure

WV State Medical License 2015 - 2025
OH State Medical License 1989 - 2018
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Elected Member The American Society for Clinical Investigation, 2004
Top MD Consumers Checkbook
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Clinical Trials

Cohort Study of the Patterns of Microvesicles in the Serum of Participants With Atopic and Non-atopic Asthma Start of enrollment: 2008 Jun 01
Completed
A Registry of COPD Patients to be Used for Future Studies Start of enrollment: 2008 Dec 01
Completed
Idiopathic Pulmonary Fibrosis Registry for Future Studies Start of enrollment: 2008 Dec 01
Completed
Immunological Characterization of Blood of Normal Individuals Start of enrollment: 2011 Mar 01
Completed
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Publications & Presentations

PubMed

Identifying biomarkers of drug use recurrence using wearable device technologies and phone applications.
James J Mahoney 3rd, Victor S Finomore, Jennifer L Marton, Jad Ramadan, Daisy G Y Thompson-Lake, Clay B Marsh, Nicolas Koch-Gallup, Manish Ranjan, Ali R Rezai, Hodder, S.> ;Drug and Alcohol Dependence. 2023 Aug 1
17 citations
Persistence and Protective Potential of SARS-CoV-2 Antibody Levels After COVID-19 Vaccination in a West Virginia Nursing Home Cohort.
Katy Smoot, Jianbo Yang, Danyel Hermes Tacker, Shelley Welch, Maryam Khodaverdi, Wes Kimble, Sijin Wen, Ayne Amjad, Clay Marsh, Peter L Perrotta, Hodder, S.> ;JAMA Network Open. 2022 Sep 1
4 citations
Flower lose, a cell fitness marker, predicts COVID-19 prognosis.
Michail Yekelchyk, Esha Madan, Jochen Wilhelm, Kirsty R. Short, António M Palma, Linbu Liao, Denise Camacho, Everlyne Nkadori, Michael T. Winters, Emily S Rice, Inês R...> ;EMBO Molecular Medicine. 2021 Nov 8
4 citations
Prediction of viral symptoms using wearable technology and artificial intelligence: A pilot study in healthcare workers.
Pierre-François D'Haese, Victor Finomore, Dmitry Lesnik, Laura Kornhauser, Tobias Schaefer, Peter E. Konrad, Clay B. Marsh, Ali R. Rezai> ;Plos One. 2021 Oct 14
12 citations
Molecular Analysis of ZNF71 KRAB in Non-Small-Cell Lung Cancer.
Qing Ye, Rehab Mohamed, Duaa Dukhlallah, Marieta Gencheva, Gangqing Hu, Martin C. Pearce, Siva Kumar Kolluri, Clay B. Marsh, Timothy D. Eubank, Alexey V. Ivanov, Nancy...> ;International Journal of Molecular Sciences. 2021 Apr 4
2 citations
COVID-19 impact on pulmonary care in rural community - a commentary.
Sunil Sharma, Robert Stansbury, Clay B. Marsh> ;Hospital Practice. 2021 Feb 17
1 citations
Intermittent Lipopolysaccharide Exposure Significantly Increases Cortical Infarct Size and Impairs Autophagy.
Ashley E. Russell, John Z. Cavendish, Ali Rai, Mya E Vannoy, Ahmad Dakhlallah, Heng Hu, Xuefang Ren, Amal O. Amer, Candice M. Brown, Clay B. Marsh, James W. Simpkins, ...> ;ASN Neuro. 2021 Feb 24
Correction: Hypoxia-Inducible Factor α Subunits Regulate Tie2-Expressing Macrophages That Influence Tumor Oxygen and Perfusion in Murine Breast Cancer.
Kayla J Steinberger, Mary A Forget, Andrey A Bobko, Nicole E Mihalik, Marieta Gencheva, Julie M Roda, Sara L Cole, Xiaokui Mo, E Hannah Hoblitzell, Randall Evans, Amy ...> ;Journal of Immunology. 2020 Dec 1
5 citations
Hypoxia-Inducible Factor α Subunits Regulate Tie2-Expressing Macrophages That Influence Tumor Oxygen and Perfusion in Murine Breast Cancer.
Kayla J Steinberger, Mary A Forget, Andrey A Bobko, Nicole E Mihalik, Marieta Gencheva, Julie M Roda, Sara L Cole, Xiaokui Mo, E Hannah Hoblitzell, Randall Evans, Amy ...> ;Journal of Immunology. 2020 Oct 15
7 citations
Stress-induced Norepinephrine Downregulates CCL2 in Macrophages to Suppress Tumor Growth in a Model of Malignant Melanoma
Kayla J. Steinberger, Michael T. Bailey, Amy C. Gross, Laura A. Sumner, Jeffrey L. Voorhees, Nisha Crouser, Jennifer M. Curry, Yijie Wang, A. Courtney DeVries, Clay B....> ;Cancer Prevention Research. 2020 Jun 9
2 citations
Risk-Stratifying COVID-19 Patients the Right Way.
Joseph Minardi, Clay B. Marsh, DM Partho P. Sengupta> ;JACC. Cardiovascular Imaging. 2020 May 27
11 citations
Constitutive AKT Activity Predisposes Lung Fibrosis by Regulating Macrophage, Myofibroblast and Fibrocyte Recruitment and Changes in Autophagy.
Duaa Dakhlallah, Yijie Wang, Tierra A. Bobo, Emily Ellis, Xiaokui Mo, Melissa G. Piper, Timothy D. Eubank, Clay B. Marsh> ;Advances in Bioscience and Biotechnology. 2019 Oct 14
34 citations
Circulating extracellular vesicle content reveals de novo DNA methyltransferase expression as a molecular method to predict septic shock.
Duaa Dakhlallah, Jon Wisler, Marieta Gencheva, Candice M. Brown, Erin R. Leatherman, Kanhaiya Singh, Kathy Brundage, Todd Karsies, Ahmad Dakhlallah, Kenneth W. Witwer,...> ;Journal of Extracellular Vesicles. 2019 Sep 28
19 citations
Of mice and men: correlations between microRNA-17∼92 cluster expression and promoter methylation in severe bronchopulmonary dysplasia.
Mary E. Robbins, Duaa Dakhlallah, Clay B. Marsh, Lynette K. Rogers, Trent E. Tipple> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2016 Sep 30
51 citations
Elevated Mirc1/Mir17-92 cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages.
Mia Tazi, Duaa Dakhlallah, Kyle Caution, Madelyn M. Gerber, Sheng-Wei Chang, Hany Khalil, Benjamin T. Kopp, Amr E. Ahmed, Kathrin Krause, Ian C. Davis, Clay B. Marsh, ...> ;Autophagy. 2016 Aug 19
87 citations
Aging is associated with hypermethylation of autophagy genes in macrophages
Hany Khalil, Mia Tazi, Kyle Caution, Amr E. Ahmed, Apurva Kanneganti, Kaivon Assani, Benjamin T. Kopp, Clay B. Marsh, Duaa Dakhlallah, Amal O. Amer> ;Epigenetics. 2016 Feb 24
4 citations
Behavioral abnormalities in mice lacking mesenchyme-specific Pten
Jeremy C. Borniger, Yasmine M. Cissé, Carmen Z. Cantemir-Stone, Brad Bolon, Randy J. Nelson, Clay B. Marsh> ;Behavioural Brain Research. 2016 May 1
34 citations
Center of excellence for mobile sensor data-to-knowledge (MD2K)
Santosh Kumar, Gregory D. Abowd, William T. Abraham, Mustafa al'Absi, J. Gayle Beck, Duen Horng Chau, Tyson Condie, David E. Conroy, Emre Ertin, Deborah Estrin, Deepak...> ;Journal of the American Medical Informatics Association. 2015 Nov 1
45 citations
Attenuation of miR-17∼92 Cluster in Bronchopulmonary Dysplasia
Lynette K. Rogers, Mary E. Robbins, Duaa Dakhlallah, Zhaogang Yang, L. James Lee, Madison Mikhail, Gerard J. Nuovo, Gloria S. Pryhuber, Gerald McGwin, Clay B. Marsh, T...> ;Annals of the American Thoracic Society. 2015 Oct 8
26 citations
A Mathematical Model of Idiopathic Pulmonary Fibrosis.
Wenrui Hao, Clay B. Marsh, Avner Friedman> ;Plos One. 2015 Sep 8
37 citations
Supernatants from stored red blood cell (RBC) units, but not RBC-derived microvesicles, suppress monocyte function in vitro.
Jennifer A. Muszynski, Justin Bale, Jyotsna Nateri, Kathleen Nicol, Yijie Wang, Valerie P. Wright, Clay B. Marsh, Mikhail A. Gavrilin, Anasuya Sarkar, Mark D. Wewers, ...> ;Transfusion. 2015 Aug 1
14 citations
The Mannose-6-phosphate analogue, PXS64, inhibits fibrosis via TGF-β1 pathway in human lung fibroblasts
Heidi Schilter, Carmen Z. Cantemir-Stone, Vladimir Leksa, Anna Ohradanova-Repic, Alison D. Findlay, Mandar Deodhar, Hannes Stockinger, Xiaomin Song, Mark P. Molloy, Cl...> ;Immunology Letters. 2015 Jun 1
51 citations
MicroRNA-133a engineered mesenchymal stem cells augment cardiac function and cell survival in the infarct heart.
Duaa Dakhlallah, Jianying Zhang, Lianbo Yu, Clay B. Marsh, Mark G. Angelos, Mahmood Khan> ;Journal of Cardiovascular Pharmacology. 2015 Mar 1
19 citations
Involvement of tumor macrophage HIFs in chemotherapy effectiveness: mathematical modeling of oxygen, pH, and glutathione.
Duan Chen, Andrey A. Bobko, Amy C. Gross, Randall Evans, Clay B. Marsh, Valery V. Khramtsov, Timothy D. Eubank, Avner Friedman> ;Plos One. 2014 Oct 8
18 citations
MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation.
Mohamed Kabbout, Duaa Dakhlallah, Sudarshana M. Sharma, Agnieszka Bronisz, Ruchika Srinivasan, Melissa G. Piper, Clay B. Marsh, Michael C. Ostrowski> ;Plos One. 2014 Jun 26
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Press Mentions

COVID-19 Hospitalizations Continue to Drop in West VirginiaApril 12th, 2022
Marshall School of Medicine Cancels Scholarship Fundraiser Due to Rise in COVID-19 CasesAugust 12th, 2021
Anti-Gun Violence Group Pledges $25 Million to Stop ShootingsAugust 2nd, 2021
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Hospital Affiliations

West Virginia University HospitalsMorgantown, West Virginia
Princeton Community HospitalPrinceton, West Virginia
Fairmont Regional Medical CenterFairmont, West Virginia