Courtney(Lynn)ZartmanMD

PubMed

• [(11)C]MK-4232: The First Positron Emission Tomography Tracer for the Calcitonin Gene-Related Peptide Receptor.
  Bell, I. M.,Gallicchio, S. N.,Stump, C. A.,Bruno, J. G.,Fan, H.,Gantert, L. T.,Hostetler, E. D.,Kemmerer, A. L.,McWherter, M.,Moore, E. L.,Mosser, S. D.,Purcell, M. L....> ;ACS Med Chem Lett. 2014 Jun 06
• MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in rats.
  Bell IM, Stump CA, Gallicchio SN, Staas DD, Zartman CB, Moore EL, Sain N, Urban M, Bruno JG, Calamari A, Kemmerer AL, Mosser SD, Fandozzi C, White RB, Zrada MM, Selnic...> ;Bioorg. Med. Chem. Lett.. 2012-06-15
• Discovery of MK-3207: A Highly Potent, Orally Bioavailable CGRP Receptor Antagonist.
  Bell IM, Gallicchio SN, Wood MR, Quigley AG, Stump CA, Zartman CB, Fay JF, Li C, Lynch JJ, Moore EL, Mosser SD, Prueksaritanont T, Regan CP, Roller S, Salvatore CA, Ka...> ;ACS Med Chem Lett. 2010-04-08
• N-arylpiperazinone inhibitors of farnesyltransferase: discovery and biological activity.
  Williams TM, Bergman JM, Brashear K, Breslin MJ, Dinsmore CJ, Hutchinson JH, MacTough SC, Stump CA, Wei DD, Zartman CB, Bogusky MJ, Culberson JC, Buser-Doepner C, Davi...> ;J. Med. Chem.. 1999-09-23
• Identification of a novel RAMP-independent CGRP receptor antagonist.
  Zartman, C. B., Bell, I. M., Gallicchio, S. N., Graham, S. L., Kane, S. A., Mallee, J. J., Rutledge, R. Z., Salvatore, C. A., Vacca, J. P., Williams, T. M.> ;Bioorg Med Chem Lett. 2011 Nov 15
• Identification of potent, highly constrained CGRP receptor antagonists.
  Stump, C. A., Bell, I. M., Bednar, R. A., Fay, J. F., Gallicchio, S. N., Hershey, J. C., Jelley, R., Kreatsoulas, C., Moore, E. L., Mosser, S. D., Quigley, A. G., Roll...> ;Bioorg Med Chem Lett. 2010 Apr 15
• Potent benzimidazolone-based CGRP receptor antagonists.
  Theberge, C. R., Bednar, R. A., Bell, I. M., Corcoran, H. A., Fay, J. F., Hershey, J. C., Johnston, V. K., Kane, S. A., Mosser, S., Salvatore, C. A., Williams, T. M., ...> ;Bioorg Med Chem Lett. 2008 Dec 01
• Identification of novel, orally bioavailable spirohydantoin CGRP receptor antagonists.
  Bell, I. M., Bednar, R. A., Fay, J. F., Gallicchio, S. N., Hochman, J. H., McMasters, D. R., Miller-Stein, C., Moore, E. L., Mosser, S. D., Pudvah, N. T., Quigley, A. ...> ;Bioorg Med Chem Lett. 2006 Dec 15
• Non-peptide calcitonin gene-related peptide receptor antagonists from a benzodiazepinone lead.
  Williams, T. M., Stump, C. A., Nguyen, D. N., Quigley, A. G., Bell, I. M., Gallicchio, S. N., Zartman, C. B., Wan, B. L., Penna, K. D., Kunapuli, P., Kane, S. A., Kobl...> ;Bioorg Med Chem Lett. 2006 May 15
• Identification and pharmacological characterization of domains involved in binding of CGRP receptor antagonists to the calcitonin-like receptor.
  Salvatore, C. A., Mallee, J. J., Bell, I. M., Zartman, C. B., Williams, T. M., Koblan, K. S., Kane, S. A.> ;Biochemistry. 2006 Feb 14
• Biochemical and structural characterization of a novel class of inhibitors of the type 1 insulin-like growth factor and insulin receptor kinases.
  Bell, I. M., Stirdivant, S. M., Ahern, J., Culberson, J. C., Darke, P. L., Dinsmore, C. J., Drakas, R. A., Gallicchio, S. N., Graham, S. L., Heimbrook, D. C., Hall, D....> ;Biochemistry. 2005 Jul 12
• Acetonitrile/water gas-phase reaction products observed by use of atmospheric pressure chemical ionization: adducts formed with sulfonamides.
  Ross, C. W., Coddington, A. B., Murphy, J. S., Wisnoski, D. D., Zartman, C. B., Ramjit, H. G.> ;Rapid Commun Mass Spectrom. 2005
• Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
  Dinsmore, C. J., Zartman, C. B., Bergman, J. M., Abrams, M. T., Buser, C. A., Culberson, J. C., Davide, J. P., Ellis-Hutchings, M., Fernandes, C., Graham, S. L., Hartm...> ;Bioorg Med Chem Lett. 2004 Feb 9
• 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency.
  Bell, I. M., Gallicchio, S. N., Abrams, M., Beese, L. S., Beshore, D. C., Bhimnathwala, H., Bogusky, M. J., Buser, C. A., Culberson, J. C., Davide, J., Ellis-Hutchings...> ;J Med Chem. 2002 Jun 6
• Conformational restriction of flexible ligands guided by the transferred noe experiment: potent macrocyclic inhibitors of farnesyltransferase.
  Dinsmore, C. J., Bogusky, M. J., Culberson, J. C., Bergman, J. M., Homnick, C. F., Zartman, C. B., Mosser, S. D., Schaber, M. D., Robinson, R. G., Koblan, K. S., Huber...> ;J Am Chem Soc. 2001 Mar 7
• Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase.
  Dinsmore, C. J., Bergman, J. M., Wei, D. D., Zartman, C. B., Davide, J. P., Greenberg, I. B., Liu, D., O'Neill, T. J., Gibbs, J. B., Koblan, K. S., Kohl, N. E., Lobell...> ;Bioorg Med Chem Lett. 2001 Feb 26
• Synthesis of conformationally constrained 5,6,7, 8-Tetrahydroimidazo[1,5-a]pyridine inhibitors of farnesyltransferase.
  Dinsmore, C. J., Zartman, C. B., Baginsky, W. F., O'Neill, T. J., Koblan, K. S., Chen, I. W., McLoughlin, D. A., Olah, T. V., Huff, J. R.> ;Org Lett. 2000 Nov 2
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