DavidAlbertBrennerMD

PubMed

• 659 citations
  Molecular and cellular mechanisms of liver fibrosis and its regression.
  Tatiana Kisseleva, David A. Brenner> ;Nature Reviews. Gastroenterology & Hepatology. 2021 Mar 1
• 13 citations
  Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice.
  Rongrong Zhou, Cristina Llorente, Jinling Cao, Livia S. Zaramela, Suling Zeng, Bei Gao, Shang-Zhen Li, Ryan D. Welch, Feng-Qing Huang, Lian-Wen Qi, Chuyue Pan, Yan Hua...> ;Cellular and Molecular Gastroenterology and Hepatology. 2021 Jan 1
• 61 citations
  Heterogeneity of HSCs in a Mouse Model of NASH
  Sara Brin Rosenthal, Xiao Liu, Souradipta Ganguly, Debanjan Dhar, Martina P. Pasillas, Eugenia Ricciardelli, Rick Z. Li, Ty D. Troutman, Tatiana Kisseleva, Christopher...> ;Hepatology. 2021 Aug 1
• 15 citations
  Necrosome-positive granulovacuolar degeneration is associated with TDP-43 pathological lesions in the hippocampus of ALS/FTLD cases.
  E Van Schoor, Marta J. Koper, Simona Ospitalieri, Lieselot Dedeene, Sandra O. Tomé, Rik Vandenberghe, David A. Brenner, Markus Otto, Jochen H. Weishaupt, Albert C. Lud...> ;Neuropathology and Applied Neurobiology. 2021 Feb 1
• 4 citations
  Previous liver regeneration induces fibro-protective mechanisms during thioacetamide-induced chronic liver injury.
  Francis D. Gratte, Sara Pasic, N. Dianah B. Abu Bakar, Jully Gogoi-Tiwari, Xiao Liu, Rodrigo Carlessi, Tatiana Kisseleva, David A. Brenner, Grant A. Ramm, John K. Olyn...> ;The International Journal of Biochemistry & Cell Biology. 2021 Feb 1
• 14 citations
  Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice.
  Kirsten Sieverding, Johannes Ulmer, Clara Bruno, Takashi Satoh, William Tsao, Axel Freischmidt, Shizuo Akira, Philip C. Wong, Albert C. Ludolph, Karin M Danzer, Christ...> ;Experimental Neurology. 2021 Jan 1
• 61 citations
  Intestinal Virome in Patients With Alcoholic Hepatitis
  Lu Jiang, Sonja Lang, Yi Duan, Xinlian Zhang, Bei Gao, Jessica Chopyk, Leila K. Schwanemann, Meritxell Ventura-Cots, Ramon Bataller, Francisco Bosques-Padilla, Elizabe...> ;Hepatology. 2020 Dec 1
• 14 citations
  The genetic landscape of axonal neuropathies in the middle-aged and elderly: Focus on MME
  Jan Senderek, Petra Lassuthova, Dagmara Kabzińska, Lisa Abreu, Jonathan Baets, Christian Beetz, Geir J. Braathen, David A. Brenner, Joline Dalton, Lois Dankwa, T Decon...> ;Neurology. 2020 Dec 15
• 11 citations
  Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism.
  Matthew Riopel, Jae-Su Moon, Gautam Bandyopadhyay, Seohee You, Kevin Lam, Xiao Liu, Tatiana Kisseleva, David A. Brenner, Yun Sok Lee> ;Molecular Metabolism. 2020 Nov 1
• 9 citations
  Traditional Chinese Medicine Fuzheng Huayu Prevents Development of Liver Fibrosis in Mice.
  Chunyan Jiang, Keiko Iwaisako, Min Cong, Karin Diggle, Tarek Hassanein, David A. Brenner, Tatiana Kisseleva> ;Archives of Clinical and Biomedical Research. 2020 Oct 20
• 19 citations
  Study of loneliness and wisdom in 482 middle-aged and oldest-old adults: a comparison between people in Cilento, Italy and San Diego, USA.
  Dilip V. Jeste, Salvatore Di Somma, Ellen E. Lee, Tanya T. Nguyen, Mara Scalcione, Alice Biaggi, Rebecca Daly, Jinyuan Liu, Xin M. Tu, Danielle Glorioso, Paola Antonin...> ;Aging & Mental Health. 2021 Nov 1
• Commentary: Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity
  Axel Freischmidt, David A. Brenner, Albert C. Ludolph, Peter M. Andersen, Jochen H. Weishaupt> ;Frontiers in Neuroscience. 2020 Sep 11
• 4 citations
  Western Diet Promotes Renal Injury, Inflammation, and Fibrosis in a Murine Model of Alström Syndrome.
  Young Chul Kim, Souradipta Ganguly, Josselin Nespoux, Brent Freeman, Haiyan Zhang, David A. Brenner, Debanjan Dhar, Volker Vallon> ;Nephron. 2020 Jul 6
• 7 citations
  Haploinsufficiency of TANK-binding kinase 1 prepones age-associated neuroinflammatory changes without causing motor neuron degeneration in aged mice.
  Clara Bruno, Kirsten Sieverding, Axel Freischmidt, Takashi Satoh, Paul Walther, Benjamin Mayer, Albert C. Ludolph, Shizuo Akira, Deniz Yilmazer-Hanke, Karin M Danzer, ...> ;Brain Communications. 2020 Jul 1
• 2 citations
  [Gene-specific treatment approaches in amyotrophic lateral sclerosis in the present and future].
  David A. Brenner, Axel Freischmidt, Albert C. Ludolph, Jochen H. Weishaupt> ;Der Nervenarzt. 2020 Apr 1
• 13 citations
  Gene specific therapies – the next therapeutic milestone in neurology
  David A. Brenner, Albert C. Ludolph, Jochen H. Weishaupt> ;Neurological Research and Practice. 2020 Sep 8
• 12 citations
  Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal ...
  Hans-Peter Müller, David A. Brenner, Francesco Roselli, Diana Wiesner, Alireza Abaei, Martin Gorges, Karin M Danzer, Albert C. Ludolph, William Tsao, Philip C. Wong, V...> ;Translational Neurodegeneration. 2019 Aug 30
• 1 citations
  The Fibrosis Across Organs Symposium: A Roadmap for Future Research Priorities.
  Jesse Roman, Teresa Barnes, Dolly Kervitsky, Gregory P. Cosgrove, Dennis E. Doherty, Andrew M. Tager, Luca Richeldi, Eric S. White, David A. Brenner, Lynn M. Schnapp, ...> ;The American Journal of the Medical Sciences. 2019 May 1
• 47 citations
  Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice.
  David A. Brenner, Kirsten Sieverding, Clara Bruno, Patrick Lüningschrör, Eva Buck, Simon Tii Mungwa, Lena Fischer, Sarah J Brockmann, Johannes Ulmer, Corinna Bliederhä...> ;The Journal of Experimental Medicine. 2019 Feb 4
• 4 citations
  Analysis of CACNA1A CAG repeat lengths in patients with familial ALS.
  David A. Brenner, Kathrin Muller, Regina Gastl, Martin Gorges, Markus Otto, Elmar H. Pinkhardt, Jan Kassubek, Jochen H. Weishaupt, Albert C. Ludolph> ;Neurobiology of Aging. 2019 Feb 1
• 24 citations
  Association of NIPA1 repeat expansions with amyotrophic lateral sclerosis in a large international cohort
  Gijs H.P. Tazelaar, Annelot M. Dekker, Joke J.F.A. van Vugt, Rick A.A. van der Spek, Henk Jan Westeneng, Lindy J.B.G. Kool, Kevin P. Kenna, Wouter van Rheenen, Sara L....> ;Neurobiology of Aging. 2019 Feb 1
• 28 citations
  Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS
  Anika M. Helferich, Sarah J Brockmann, Joerg Reinders, Dhruva Deshpande, Karlheinz Holzmann, David A. Brenner, Peter M. Andersen, Susanne Petri, Dietmar Rudolf Thal, J...> ;Cellular and Molecular Life Sciences. 2018 Jul 20
• LRRK2 contributes to monocyte dysregulation in Parkinson's disease.
  Bliederhaeuser C, Zondler L, Grozdanov V, Ruf WP, Brenner D, Melrose HL, Bauer P, Ludolph AC, Gillardon F, Kassubek J, Weishaupt JH, Danzer KM> ;Acta Neuropathol Commun. 2016-11-24
• 23 citations
  Magnetic resonance elastography identifies fibrosis in adults with alpha-1 antitrypsin deficiency liver disease: a prospective study
  Rebecca G. Kim, Phirum Nguyen, Ricki Bettencourt, Parambir S. Dulai, William Haufe, Jacob M. Hooker, Jeet Minocha, Mark A. Valasek, H. Aryafar, David A. Brenner, Claud...> ;Alimentary Pharmacology & Therapeutics. 2016 Aug 1
• NEK1 mutations in familial amyotrophic lateral sclerosis.
  Brenner D, Müller K, Wieland T, Weydt P, Böhm S, Lulé D, Hübers A, Neuwirth C, Weber M, Borck G, Wahlqvist M, Danzer KM, Volk AE, Meitinger T, Strom TM, Otto M, Kassub...> ;Brain. 2016-05-01
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