DavidFeifelMDPhD

Psychiatry • La Jolla, CA

Psychopharmacology, Psychosomatic Medicine

Physician

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Office
3252 holiday court
Suite 112
La Jolla, CA 92037
Phone+1 858-412-4130

Fax+1 858-412-5088
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Education & Training

University of California (San Diego) Medical CenterResidency, Psychiatry, 1992 - 1995
University of Toronto Faculty of MedicineClass of 1991

Certifications & Licensure

CA State Medical License 1992 - 2024
American Board of Psychiatry and Neurology Psychiatry

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Clinical Trials

Naturalistic Study, Comparison of Divalproex Extended Release (ER) and Quetiapine for Adults With Acute Mania or Mixed Episodes Start of enrollment: 2006 Dec 01
Completed
Phase 4
Oxytocin Add on Study for Stable Schizophrenic Patients Start of enrollment: 2008 Mar 01
Terminated
Not Applicable
Oxytocin Add-on Study for Stable Anxiety Patients Start of enrollment: 2009 Feb 01
Terminated
Not Applicable
Oxytocin Add-on for Stable Depressed Patients Start of enrollment: 2010 Oct 01
Terminated
Not Applicable
Antipsychotic Effects of Oxytocin Start of enrollment: 2011 Jun 01
Terminated
Not Applicable
Evaluation of Deep Transcranial Magnetic Stimulation (DTMS) With the H-ADD Coil as an Aid to Smoking Cessation. Start of enrollment: 2014 Aug 20
Completed
Phase 3
Open-label Study of the Efficacy of Intranasal Oxytocin in Schizophrenia Start of enrollment: 2012 Mar 01
Terminated
Not Applicable
A Safety & Efficacy Study With Deep Transcranial Magnetic Stimulation for the Treatment of Post-Traumatic Stress Disorder (PTSD) Start of enrollment: 2016 Nov 17
Terminated
Not Applicable
Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder Start of enrollment: 2017 Nov 27
Completed
Not Applicable
Testing the Value of Smartphone Assessments of People With Mood Disorders Start of enrollment: 2017 Aug 08
Completed
Post Hoc Analysis and Clinical Data Collection for Subjects Tested With Brain Network Activation (BNA™) Technology Start of enrollment: 2018 May 01
Recruiting
The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression Start of enrollment: 2019 Mar 01
Completed
Phase 2
Combining H1-Coil Deep Transcranial Magnetic Stimulation (dTMS) and App-guided CBT in Subjects With Major Depression Disorder (MDD) Start of enrollment: 2019 Aug 26
Recruiting
The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant Depression Start of enrollment: 2020 Aug 10
Completed
Phase 2
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Publications & Presentations

PubMed

Effects of chronic intranasal oxytocin on visual attention to faces vs. natural scenes in older adults.
Alayna Shoenfelt, Didem Pehlivanoglu, Tian Lin, Maryam Ziaei, David Feifel, Natalie C Ebner> ;Psychoneuroendocrinology. 2024 Mar 4
1 citations
National Network of Depression Centers position statement: Insurance coverage for intravenous ketamine in treatment-resistant major depressive disorder.
Mark J Niciu, Robert C Meisner, Brent R Carr, Ali A Farooqui, David Feifel, Adam Kaplin, E Jeremy Kendrick, Paul M Kim, Christopher D Schneck, Jennifer L Vande Voort, ...> ;Journal of Affective Disorders. 2024 Feb 1
1 citations
Four-week intranasal oxytocin administration reduces attachment avoidance in older women.
Kylie A Wright, Rebecca Polk, Tian Lin, David Feifel, Natalie C Ebner> ;Hormones and Behavior. 2023 Sep 1
11 citations
Psilocybin for treatment resistant depression in patients taking a concomitant SSRI medication.
Guy M Goodwin, Megan Croal, David Feifel, John R Kelly, Lindsey Marwood, Sunil Mistry, Veronica O'Keane, Stephanie Knatz Peck, Hollie Simmons, Claudia Sisa, Susan C St...> ;Neuropsychopharmacology. 2023 Sep 1
25 citations
Single-dose psilocybin for a treatment-resistant episode of major depression: Impact on patient-reported depression severity, anxiety, function, and quality of life.
Guy M Goodwin, Scott T Aaronson, Oscar Alvarez, Merve Atli, James C Bennett, Megan Croal, Charles DeBattista, Boadie W Dunlop, David Feifel, David J Hellerstein, Muham...> ;Journal of Affective Disorders. 2023 Apr 14
7 citations
Pursuing personalized medicine for depression by targeting the lateral or medial prefrontal cortex with Deep TMS.
Abraham Zangen, Samuel Zibman, Aron Tendler, Noam Barnea-Ygael, Uri Alyagon, Daniel M Blumberger, Geoffrey Grammer, Hadar Shalev, Tatiana Gulevski, Tanya Vapnik, Alexa...> ;JCI Insight. 2023 Feb 22
4 citations
Intranasal oxytocin modulates the salience network in aging.
Peiwei Liu, Tian Lin, David Feifel, Natalie C Ebner> ;Neuroimage. 2022 Jun 1
5 citations
Age-Related Differences in Amygdala Activation Associated With Face Trustworthiness but No Evidence of Oxytocin Modulation.
Tian Lin, Didem Pehlivanoglu, Maryam Ziaei, Peiwei Liu, Adam J Woods, David Feifel, Håkan Fischer, Natalie C Ebner> ;Frontiers in Psychology. 2022 Jan 1
76 citations
Repetitive transcranial magnetic stimulation for smoking cessation: a pivotal multicenter double-blind randomized controlled trial
Abraham Zangen, Hagar Moshe, Diana Martinez, Noam Barnea-Ygael, Tanya Vapnik, Alexander Bystritsky, Walter Duffy, Doron Toder, Leah S. Casuto, Moran Lipkinsky Grosz, E...> ;World Psychiatry. 2021 Oct 1
Reply to Tendler et al.
Joseph J. Taylor, Noam G. Newberger, Adam P. Stern, Angela Phillips, David Feifel, Rebacca A. Betensky, Daniel Z. Press> ;Brain Stimulation. 2021 Aug 13
13 citations
Seizure risk with repetitive TMS: Survey results from over a half-million treatment sessions.
Joseph J. Taylor, Noam G. Newberger, Adam P. Stern, Angela Phillips, David Feifel, Rebecca A. Betensky, Daniel Z. Press> ;Brain Stimulation. 2021 Jun 13
8 citations
Safety and tolerability of chronic intranasal oxytocin in older men: results from a randomized controlled trial
Jillian M. Rung, Marilyn Horta, Erin M Tammi, Eliany Perez, Marite C Ojeda, Tian Lin, Griffin Harris, Jessie Somerville, Dinia Salmeron, Susan E Beltz, Bhanuprasad San...> ;Psychopharmacology. 2021 May 12
32 citations
Deep Transcranial Magnetic Stimulation Combined With Brief Exposure for Posttraumatic Stress Disorder: A Prospective Multisite Randomized Trial.
Moshe Isserles, Aron Tendler, Yiftach Roth, Alexander Bystritsky, Daniel M. Blumberger, Herbert E. Ward, David Feifel, Laura Viner, Walter Duffy, Joseph Zohar, Corey J...> ;Biological Psychiatry. 2021 May 4
23 citations
A longitudinal case series of IM ketamine for patients with severe and enduring eating disorders and comorbid treatment-resistant depression
Terry A. Schwartz, Mary Ellen Trunko, David Feifel, Emily Lopez, Danika Peterson, Guido K.W. Frank, Walter H. Kaye> ;Clinical Case Reports. 2021 Apr 4
6 citations
Age and intranasal oxytocin effects on trust-related decisions after breach of trust: Behavioral and brain evidence.
Ian Frazier, Tian Lin, Peiwei Liu, Sondre Skarsten, David Feifel, Natalie C. Ebner> ;Psychology and Aging. 2021 Feb 1
4 citations
Development of an innovative adult attention-deficit hyperactivity disorder clinic
Kelly C. Lee, Estelle Kim, Jaye Kim, Benjamin J. Malcolm, Grace M. Kuo, Anne Bird, David Feifel> ;The Mental Health Clinician. 2020 Sep 1
16 citations
Safety of Repeated Administration of Parenteral Ketamine for Depression
David Feifel, David Dadiomov, Kelly C. Lee> ;Pharmaceuticals. 2020 Jul 13
43 citations
Chronic oxytocin administration as a tool for investigation and treatment: A cross-disciplinary systematic review
Marilyn Horta, Kathryn Kaylor, David Feifel, Natalie C. Ebner> ;Neuroscience and Biobehavioral Reviews. 2020 Jan 1
19 citations
Oxytocin alters patterns of brain activity and amygdalar connectivity by age during dynamic facial emotion identification.
Marilyn Horta, Maryam Ziaei, Tian Lin, Eric C. Porges, Håkan Fischer, David Feifel, R. Nathan Spreng, Natalie C. Ebner> ;Neurobiology of Aging. 2019 Jun 1
196 citations
Efficacy and Safety of Deep Transcranial Magnetic Stimulation for Obsessive-Compulsive Disorder: A Prospective Multicenter Randomized Double-Blind Placebo-Controlled T...
Lior Carmi, Aron Tendler, Alexander Bystritsky, Eric Hollander, Daniel M. Blumberger, Jeff Daskalakis, Herbert E. Ward, Kyle A.B. Lapidus, Wayne K. Goodman, Leah S. Ca...> ;The American Journal of Psychiatry. 2019 May 21
16 citations
Oxytocin improves probabilistic reversal learning but not effortful motivation in Brown Norway rats.
Benjamin Z Roberts, Jared W. Young, Yinong V He, Zackary A. Cope, Paul D. Shilling, David Feifel> ;Neuropharmacology. 2019 May 15
Roles and Qualifications of TMS Treatment Team Members.
David Feifel, David L. Dunner, Daniel Z. Press> ;The Journal of Clinical Psychiatry. 2018 Feb 21
22 citations
Low-dose ketamine for treatment resistant depression in an academic clinical practice setting.
David Feifel, Benjamin J. Malcolm, Danielle Boggie, Kelly C. Lee> ;Journal of Affective Disorders. 2017 Oct 15
1 citations
Network Meta-analysis in Mental Health Research
David Feifel> ;JAMA Psychiatry. 2017 Aug 1
12 citations
Breaking Sad: Unleashing the Breakthrough Potential of Ketamine's Rapid Antidepressant Effects.
David Feifel> ;Drug Development Research. 2016 Nov 1
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Press Mentions

The Wellness Industry Is Sneaking Medication Stigma Back into the Mainstream — & Here’s How to Fight ItMay 13th, 2023
Dosages, Side Effects, and More – Forbes HealthApril 19th, 2023
Could a Racing Heart Trigger Anxiety, Rather Than the Other Way Around?March 9th, 2023
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Grant Support

Neurotensin-1 Receptor As A Therapeutic Target For SchizophreniaNational Institute Of Mental Health2009–2012
1/2-Anti-Psychotic Effects Of OxytocinNational Institute Of Mental Health2011
A Novel Animal Model Of Relevance To SchizophreniaNational Institute Of Mental Health2005–2009
Antipsychotic-Like Drug Effects Of NeurotensinNational Institute Of Mental Health2002–2004
Olanzapine + Devalproex VS Placebo + DevalproexNational Center For Research Resources2000–2002