David Gorski, MD

David Gorski, MD

General Surgery Detroit, MI

Associate Professor of Surgery, Wayne State University

Office Address

  • 4100 John R St.
    Detroit, MI 48201
    Phone: (313) 576-8490

David Gorski, MD

General Surgery Detroit, MI

Associate Professor of Surgery, Wayne State University


  • I am an academic surgical oncologist specializing in breast surgery. I run my own laboratory, in which I study glutamate signaling as a therapeutic target in triple negative breast cancer, tumor angiogenesis, and the contribution of microRNAs to breast cancer progression. I have been funded by the Department of Defense, the NIH, the Conquer Cancer Foundation of ASCO, and the Robert Wood Johnson Foundation.. Currently, I am the chief of the Breast Surgery Section at the Wayne State University School of Medicine and the medical director of the Alexander J. Walt Comprehensive Breast Center.

Clinical Specialties & Interests

  • Breast, Surgical Oncology (Other than Breast)
  • Clinical Interests: Homeodomain Proteins; Mice; Inbred C57BL Mice; Pathologic Neovascularization; Vascular Endothelium; Homeobox Genes; Melanoma; Antineoplastic Agents

Education & Training

  • University of ChicagoUniversity of Chicago
  • Case Western Reserve University - University HospitalsCase Western Reserve University - University Hospitals
  • Case Western Reserve UniversityCase Western Reserve University
  • Case Western Reserve University - University HospitalsCase Western Reserve University - University Hospitals
  • University of Michigan Medical SchoolUniversity of Michigan Medical School
  • University of MichiganUniversity of Michigan

Certifications & Licensure

  • MI State Medical LicenseMI State Medical License2008 - 2018
  • OH State Medical LicenseOH State Medical License1990 - 2017
  • American Board of SurgerySurgery

    Awards, Honors, & Recognition

    • American Society of Clinical Oncology Advanced Clinical Research2007
    • MetroHealth Medical Center Resident Research1994
    • Graduation with Honors and High Distinction in Chemistry1984

    Publications & Presentations


    Journal Articles

    • Level of expression of vascular endothelial growth factor C (VEGF-C) correlates with stage of local/regional progression in patients with melanoma.  Goydos, J. S., and D. H. Gorski, Clin. Cancer Res. 9:5962-5967
    • Detection of mutations in the mitogen-activated protein kinase (MAPK) pathway in human melanoma.  Alsina, J., D. H. Gorski, F. J. Germino, W. Shih, S.-E. Lu, Z.-G. Zhang, J.-M. Yang, W. N. Hait, and J. S. Goydos, Clin. Cancer Res. 9:6419-6425
    • Metabotropic Glutamate Receptor-1: A potential therapeutic target for the treatment of breast cancer.  Speyer, C. L., J. S. Smith, M. Banda, T. Mekani, J. A. deVries, and D. H. Gorski, Breast Cancer Treat. Res.132:565-573

    Books/Book Chapters

    • Gene Therapy of Cancer: Translational Approaches from Preclinical Studies to Clinical Implementation. Chapter: Strategies for combining gene therapy with ionizing radiation to improve antitumor efficacy 
      Gorski, D. H., H. J. Mauceri, and R. R. Weichselbaum
      Editors: Lattime, E.C., and S. L. Gerson.Academic Press, San Diego
      Edition 2,


    • Improved tumor response of esophageal adenocarcinoma to combined treatment with anti-VEGF antibody and radiation. N. Jaskowiak, D. Gorski, R. Salloum, H. Mauceri, S. Seetharam, R. Weichselbaum, M. Posner, The Society of Surgical Oncology Meeting, New Orleans, LA
    • A new isocoumarin, NM3, selectively inhibits endothelial cell growth in vitro. R. Salloum, H. Mauceri, N. Jaskowiak, D. Gorski, S. Seetharam, D. Hari, M. Posner, D. Kufe, R. Weichselbaum, The Society of Surgical Oncology Meeting, New Orleans, LA
    • The growth arrest-specific homeobox gene Gax: A potential negative regulator of angiogenesis. D. Gorski, The Society of Surgical Oncology Meeting, Washington, D.C


    • Gax: A novel homeobox gene that causes cell-cycle arrest in vascular myocytes. MetroHealth Medical Center/Case Western Reserve University School of Medicine
    • Synergism between angiogenesis inhibition and radiation therapy in control of Lewis lung carcinoma growth. Charles Huggins Research Conference, The University of Chicago, Chicago, Illinois
    • Homeobox genes in vascular smooth muscle cells: Toward a gene therapy of blood vessel diseases? Department of Surgery Grand Rounds, Case Western Reserve University, Cleveland, Ohio


    • Vaccines. Gorski, DH, Radio interview on Skeptically Speaking, CJSR 88.5 FM, Edmonton, Alberta, Canada
    • So-Called Complementary and Alternative Medicine. Gorski DH, Podcast interview on For Good Reason
    • Susan G. Komen Race for the Cure. Gorski DH, Television interview on FOX 2 Detroit News

    Insurance Accepted

    • Aetna Choice POS II
    • BCBS Blue Card PPO
    • BCBS Illinois PPO
    • CIGNA Open Access
    • Cofinity PPO
    • First Health PPO
    • Great West PPO
    • Health Net California Large Group PPO
    • Humana ChoiceCare Network PPO
    • Multiplan PHCS PPO
    • Multiplan PHCS PPO - Kaiser
    • Multiplan PPO
    • PriorityHealth HMO
    • United Healthcare - Direct Choice Plus POS
    • United Healthcare - Direct Options PPO
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