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David Hough, MD, Psychiatry, Morrisville, PA

DavidHoughMD

Psychiatry • Morrisville, PA

Geriatric Psychiatry, Clinical Pharmacology

Neuroscience Drug Development Consultant

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Summary

  • David Hough, MD is currently serving as the Chief Medical Officer for Freedom Biosciences. Prior to this role, Dr Hough was a Vice-President at Janssen Research and Development, LLC (Johnson& Johnson) where he served for 17 years in several different leadership roles. His latest position was the SPRAVATO (esketamine) compound development team leader overseeing the development program through two severe mood disorder indications. He was responsible for all the medical, scientific, manufacturing, quality, preclinical, and commercial aspects of the program. Prior to that he was the schizophrenia disease area leader and the development team leader for paliperidone. He played a pivotal role in the development programs for oral INVEGA (paliperidone), INVEGA SUSTENNA/XEPLION (paliperidone palmitate) 1-month and 3-month formulations. Dave is a graduate of West Point and served for several years as a regular Army officer before attending medical school at the Uniformed Services University of the Health Sciences (USUHS) in Bethesda, Maryland. After completing residency training in Psychiatry at Walter Reed Medical Center in Washington DC, he served for 10 years as an Army psychiatrist at two separate community hospitals and on faculty at a psychiatry residency program in Honolulu, Hawaii. He supervised numerous psychiatry residents and allied mental health professionals serving as head of outpatient clinics and behavioral health departments in different military hospitals.

    He completed a two-year research fellowship in Clinical Pharmacology jointly sponsored by USUHS and Walter Reed Army Institute of Research. He is board certified in both Adult and Geriatric Psychiatry and held an Adjunct Assistant Professor of Psychiatry position at USUHS for several years. He has authored numerous publications in peer reviewed journals, is a reviewer for several journals, and was an examiner for the American Board of Psychiatry and Neurology.

Education & Training

  • National Capital Consortium
    National Capital ConsortiumFellowship, Clinical Pharmacology, 1993 - 1995
  • National Capital Consortium
    National Capital ConsortiumResidency, Psychiatry, 1988 - 1991
  • National Capital Consortium
    National Capital ConsortiumInternship, Transitional Year, 1987 - 1988
  • UniforMed Services University of the Health Sciences F. Edward Hebert School of Medicine
    UniforMed Services University of the Health Sciences F. Edward Hebert School of MedicineClass of 1987

Certifications & Licensure

  • PA State Medical License
    PA State Medical License 2004 - 2020
  • American Board of Psychiatry and Neurology Psychiatry
  • AOA Board of Neurology and Psychiatry Geriatric Psychiatry (CAQ)

Publications & Presentations

PubMed

Journal Articles

  • Patient preferences for ketamine-based antidepressant treatments in treatment-resistant depression: Results from a clinical trial and panel  
    AO Fairchild, EG Katz, SD Reed, FR Johnson, A DiBernardo, DW Hough, B Levitan, Neurology, Psychiatry and Brain Research, 9/1/2020
  • Approval of Esketamine for treatment-resistant depression  
    Singh, JB, Daly, E, Mathews, M, Fedgchin, M, Popova, V, Hough, D, Drevets, W., The Lancet Psychiatry, 3/2020

Abstracts/Posters

  • Suramin intravenous infusion for treating boys with autism spectrum disorder: results of a 14-week, randomized, double blind, placebo controlled, multidose, phase 2 study
    David Hough, Alice Mao, Michael Aman, Fan-fan Yu, Constance Smith-Hicks, Reymundo Lozano, Veronica Martinez-Cerdeno, Michael Derby, Zachery Rome, Robert Findling, American Academy of Child and Adolescent Psychiatry Research Pipeline Presentation, Virtual Meeting, 10/27/2021

Press Mentions

  • Ketamine Depression Treatment Passes Another Trial, but Isn’t for Everyone
    Ketamine Depression Treatment Passes Another Trial, but Isn’t for EveryoneSeptember 20th, 2019
  • Why the New Ketamine-like Nasal Spray Is Worrying Some Physicians
    Why the New Ketamine-like Nasal Spray Is Worrying Some PhysiciansJune 14th, 2019
  • Inside the Los Angeles Clinic That Uses Ketamine to Treat Depression
    Inside the Los Angeles Clinic That Uses Ketamine to Treat DepressionJune 19th, 2017

Dr. David Hough, Dr. David Hough, MD, Dr. D Hough