DavidJosephJohnsonMD

PubMed

• Cytochrome b mutation Y268S conferring the atovaquone resistance phenotype in the malaria parasite results in reduced parasite bc1 catalytic turnover and protein expre...
  Fisher, N., Abd Majid, R., Antoine, T., Al-Helal, M., Warman, A.J., Johnson, D.J., Lawrenson, A.S., Ranson, H., O'Neill, P.M., Ward, S.A., Biagini, G.A.> ;J Biol Chem. 2012 Mar 23
• Probing the multifactorial basis of Plasmodium falciparum quinine resistance: evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE.
  Nkrumah, L. J., Riegelhaupt, P. M., Moura, P., Johnson, D. J., Patel, J., Hayton, K., Ferdig, M. T., Wellems, T. E., Akabas, M. H., Fidock, D. A.> ;Mol Biochem Parasitol. 2009 Jun 01
• Role of known molecular markers of resistance in the antimalarial potency of piperaquine and dihydroartemisinin in vitro.
  Muangnoicharoen, S., Johnson, D.J., Looareesuwan, S., Krudsood, S., Ward, S.A.> ;Antimicrob Agents Chemother. 2009-04-01
• Plasmodium falciparum and dihydrofolate reductase I164L mutations in Africa.
  Alker, A.P., Juliano, J.J., Meshnick, S.R., Owen, A., Ochong, E., Bell, D.J., Johnson, D.J., d'Alessandro, U., Mulenga, M., Muangnoicharoen, S., Van Geertruyden, J.P.,...> ;Antimicrob Agents Chemother. 2009 Apr
• Plasmodium falciparum strains harboring dihydrofolate reductase with the I164L mutation are absent in Malawi and Zambia even under antifolate drug pressure.
  Ochong, E., Bell, D.J., Johnson, D.J., D'Alessandro, U., Mulenga, M., Muangnoicharoen, S., Van Geertruyden, J., Winstanley, P.A., Bray, P.G., Ward, S.A., Owen, A.> ;Antimicrob Agents Chemother. 2008 Nov
• Drug-regulated expression of Plasmodium falciparum P-glycoprotein homologue 1: a putative role for nuclear receptors.
  Johnson, D.J., Owen, A., Plant, N., Bray, P.G., Ward, S.A.> ;Antimicrob Agents Chemother. 2008 Apr
• Toxicity and hazard of a mixture of SSRIs to zooplankton communities evaluated in aquatic microcosms.
  Laird, B. D., Brain, R. A., Johnson, D. J., Wilson, C. J., Sanderson, H., Solomon, K. R.> ;Chemosphere. 2007 Oct
• Toxicity and hazard of selective serotonin reuptake inhibitor antidepressants fluoxetine, fluvoxamine, and sertraline to algae.
  Johnson, D.J., Sanderson, H., Brain, R.A., Wilson, C.J., Solomon, K.R.> ;Ecotoxicol Environ Saf. 2007 May
• PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX.
  Bray, P. G., Mungthin, M., Hastings, I. M., Biagini, G. A., Saidu, D. K., Lakshmanan, V., Johnson, D. J., Hughes, R. H., Stocks, P. A., O'Neill, P. M., Fidock, D. A., ...> ;Mol Microbiol. 2006 Oct
• Effects of a mixture of tetracyclines to Lemna gibba and Myriophyllum sibiricum evaluated in aquatic microcosms.
  Brain, R. A., Wilson, C. J., Johnson, D. J., Sanderson, H., Bestari, K. J., Hanson, M. L., Sibley, P. K., Solomon, K. R.> ;Environ Pollut. 2005 Dec
• Exposure assessment and microcosm fate of selected selective serotonin reuptake inhibitors.
  Johnson, D.J., Sanderson, H., Brain, R.A., Wilson, C.J., Bestari, K.T., Solomon, K.R.> ;Regul Toxicol Pharmacol. 2005 Aug
• A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance.
  Lakshmanan, V., Bray, P. G., Verdier-Pinard, D., Johnson, D. J., Horrocks, P., Muhle, R. A., Alakpa, G. E., Hughes, R. H., Ward, S. A., Krogstad, D. J., Sidhu, A. B., ...> ;EMBO J. 2005 Jul 6
• Dissipation of oxytetracycline, chlortetracycline, tetracycline and doxycycline using HPLC-UV and LC/MS/MS under aquatic semi-field microcosm conditions.
  Sanderson, H., Ingerslev, F., Brain, R. A., Halling-Sørensen, B., Bestari, J. K., Wilson, C. J., Johnson, D. J., Solomon, K. R.> ;Chemosphere. 2005 Jul
• Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum.
  Brain, R. A., Bestari, K. J., Sanderson, H., Hanson, M. L., Wilson, C. J., Johnson, D. J., Sibley, P. K., Solomon, K. R.> ;Environ Pollut. 2005 Feb
• Structural and functional responses of plankton to a mixture of four tetracyclines in aquatic microcosms.
  Wilson, C.J., Brain, R.A., Sanderson, H., Johnson, D.J., Bestari, K.T., Sibley, P.K., Solomon, K.R.> ;Environ Sci Technol. 2004 Dec 1
• Microcosm evaluation of the effects of an eight pharmaceutical mixture to the aquatic macrophytes Lemna gibba and Myriophyllum sibiricum.
  Brain, R. A., Johnson, D. J., Richards, S. M., Hanson, M. L., Sanderson, H., Lam, M. W., Young, C., Mabury, S. A., Sibley, P. K., Solomon, K. R.> ;Aquat Toxicol. 2004 Oct 18
• Toxicity classification and evaluation of four pharmaceuticals classes: antibiotics, antineoplastics, cardiovascular, and sex hormones.
  Sanderson, H., Brain, R. A., Johnson, D. J., Wilson, C. J., Solomon, K. R.> ;Toxicology. 2004 Oct 15
• Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.
  Johnson, D.J., Fidock, D.A., Mungthin, M., Lakshmanan, V., Sidhu, A.S., Bray, P.G., Ward, S.A.> ;Mol Cell. 2004 Sep 24
• Aquatic persistence of eight pharmaceuticals in a microcosm study.
  Lam, M.W., Young, C.J., Brain, R.A., Johnson, D.J., Hanson, M.A., Wilson, C.J., Richards, S.M., Solomon, K.R., Mabury, S.A.> ;Environ Toxicol Chem. 2004 Jun
• Ranking and prioritization of environmental risks of pharmaceuticals in surface waters.
  Sanderson, H., Johnson, D.J., Reitsma, T., Brain, R.A., Wilson, C.J., Solomon, K.R.> ;Regul Toxicol Pharmacol. 2004 Apr
• Effects of pharmaceutical mixtures in aquatic microcosms.
  Richards, S.M., Wilson, C.J., Johnson, D.J., Castle, D.M., Lam, M., Mabury, S.A., Sibley, P.K., Solomon, K.R.> ;Environ Toxicol Chem. 2004 Apr
• Effects of 25 pharmaceutical compounds to Lemna gibba using a seven-day static-renewal test.
  Brain, R.A., Johnson, D.J., Richards, S.M., Sanderson, H., Sibley, P.K., Solomon, K.R.> ;Environ Toxicol Chem. 2004 Feb
• Probabilistic hazard assessment of environmentally occurring pharmaceuticals toxicity to fish, daphnids and algae by ECOSAR screening.
  Sanderson, H., Johnson, D. J., Wilson, C. J., Brain, R. A., Solomon, K. R.> ;Toxicol Lett. 2003 Oct 15
• Join now to see all