DavidWatsonRiceMD

PubMed

• Discrimination of Potent Inhibitors of Toxoplasma gondii Enoyl-Acyl Carrier Protein Reductase by a Thermal Shift Assay.
  Afanador, G. A.,Muench, S. P.,McPhillie, M.,Fomovska, A.,Schön, A.,Zhou, Y.,Cheng, G.,Stec, J.,Freundlich, J. S.,Shieh, H. M.,Anderson, J. W.,Jacobus, D. P.,Fidock, D....> ;Biochemistry. 2013 Dec 04
• Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii.
  Stec, J.,Fomovska, A.,Afanador, G. A.,Muench, S. P.,Zhou, Y.,Lai, B. S.,El Bissati, K.,Hickman, M. R.,Lee, P. J.,Leed, S. E.,Auschwitz, J. M.,Sommervile, C.,Woods, S.,...> ;ChemMedChem. 2013 Jul
• Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase.
  Cheng, G.,Muench, S. P.,Zhou, Y.,Afanador, G. A.,Mui, E. J.,Fomovska, A.,Lai, B. S.,Prigge, S. T.,Woods, S.,Roberts, C. W.,Hickman, M. R.,Lee, P. J.,Leed, S. E.,Auschw...> ;Bioorg. Med. Chem. Lett.. 2013 Apr 1
• A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A.
  Cruz-Migoni, A., Hautbergue, G.M., Artymiuk, P.J., Baker, P.J., Bokori-Brown, M., Chang, C., Dickman, M.J., Essex-Lopresti, A., Harding, S.V., Mahadi, N.M., Marshall, ...> ;Science. 2011 Nov 11
• Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase.
  Tipparaju, S.K., Muench, S.P., Mui, E.J., Ruzheinikov, S.N., Lu, J.Z., Hutson, S.L., Kirisits, M.J., Prigge, S.T., Roberts, C.W., Henriquez, F.L., Kozikowski, A.P., Ri...> ;J Med Chem. 2010 Sep 9
• The single-domain globin from the pathogenic bacterium Campylobacter jejuni: novel D-helix conformation, proximal hydrogen bonding that influences ligand binding, and ...
  Shepherd, M., Barynin, V., Lu, C., Bernhardt, P.V., Wu, G., Yeh, S., Egawa, T., Sedelnikova, S.E., Rice, D.W., Wilson, J.L., Poole, R.K.> ;J Biol Chem. 2010 Apr 23
• Active site dynamics in the zinc-dependent medium chain alcohol dehydrogenase superfamily.
  Baker, P.J., Britton, K.L., Fisher, M., Esclapez, J., Pire, C., Bonete, M.J., Ferrer, J., Rice, D.W.> ;Proc Natl Acad Sci U S A. 2009-01-20
• An inhibitor of FtsZ with potent and selective anti-staphylococcal activity.
  Haydon, D.J., Stokes, N.R., Ure, R., Galbraith, G., Bennett, J.M., Brown, D.R., Baker, P.J., Barynin, V.V., Rice, D.W., Sedelnikova, S.E., Heal, J.R., Sheridan, J.M., ...> ;Science. 2008-09-19
• Molecular basis for resistance of acanthamoeba tubulins to all major classes of antitubulin compounds.
  Henriquez, F.L., Ingram, P.R., Muench, S.P., Rice, D.W., Roberts, C.W.> ;Antimicrob Agents Chemother. 2008 Mar
• Crystal structure of S. aureus YlaN, an essential leucine rich protein involved in the control of cell shape.
  Xu, L., Sedelnikova, S.E., Baker, P.J., Hunt, A., Errington, J., Rice, D.W.> ;Proteins. 2007 Aug 1
• The essential GTPase YphC displays a major domain rearrangement associated with nucleotide binding.
  Muench, S.P., Xu, L., Sedelnikova, S.E., Rice, D.W.> ;Proc Natl Acad Sci U S A. 2006 Aug 15
• Analysis of protein solvent interactions in glucose dehydrogenase from the extreme halophile Haloferax mediterranei.
  Britton, K.L., Baker, P.J., Fisher, M., Ruzheinikov, S., Gilmour, D.J., Bonete, M., Ferrer, J., Pire, C., Esclapez, J., Rice, D.W.> ;Proc Natl Acad Sci U S A. 2006 Mar 28
• Structure and mechanism of imidazoleglycerol-phosphate dehydratase.
  Glynn, S.E., Baker, P.J., Sedelnikova, S.E., Davies, C.L., Eadsforth, T.C., Levy, C.W., Rodgers, H.F., Blackburn, G.M., Hawkes, T.R., Viner, R., Rice, D.W.> ;Structure. 2005 Dec
• Substrate-induced conformational changes in Bacillus subtilis glutamate racemase and their implications for drug discovery.
  Ruzheinikov, S.N., Taal, M.A., Sedelnikova, S.E., Baker, P.J., Rice, D.W.> ;Structure. 2005 Nov
• Maternal inheritance and stage-specific variation of the apicoplast in Toxoplasma gondii during development in the intermediate and definitive host.
  Ferguson, D. J.,Henriquez, F. L.,Kirisits, M. J.,Muench, S. P.,Prigge, S. T.,Rice, D. W.,Roberts, C. W.,McLeod, R. L.> ;Eukaryot Cell. 2005 Apr
• Science success, narrative theories of personality, and race self complexity: is race represented in the identity construction of African American adolescents?
  Winston, C.E., Rice, D.W., Bradshaw, B.J., Lloyd, D., Harris, L.T., Burford, T.I., Clodimir, G., Kizzie, K., Carothers, K.J., McClair, V., Burrell, J.> ;New Dir Child Adolesc Dev. 2004
• The structure of Escherichia coli RusA endonuclease reveals a new Holliday junction DNA binding fold.
  Rafferty, J.B., Bolt, E.L., Muranova, T.A., Sedelnikova, S.E., Leonard, P., Pasquo, A., Baker, P.J., Rice, D.W., Sharples, G.J., Lloyd, R.G.> ;Structure. 2003 Dec
• Crystal structure of Pyrococcus furiosus phosphoglucose isomerase. Implications for substrate binding and catalysis.
  Berrisford, J.M., Akerboom, J., Turnbull, A.P., de Geus, D., Sedelnikova, S.E., Staton, I., McLeod, C.W., Verhees, C.H., van der Oost, J., Rice, D.W., Baker, P.J.> ;J Biol Chem. 2003 Aug 29
• Squash glycerol-3-phosphate (1)-acyltransferase. Alteration of substrate selectivity and identification of arginine and lysine residues important in catalytic activity.
  Slabas, A.R., Kroon, J.M., Scheirer, T.P., Gilroy, J.S., Hayman, M., Rice, D.W., Turnbull, A.P., Rafferty, J.B., Fawcett, T., Simon, W.J.> ;J Biol Chem. 2002 Nov 15
• Single amino acid substitution in Bacillus sphaericus phenylalanine dehydrogenase dramatically increases its discrimination between phenylalanine and tyrosine substrates.
  Seah, S.K., Britton, K.L., Rice, D.W., Asano, Y., Engel, P.C.> ;Biochemistry. 2002 Sep 24
• X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site.
  Roujeinikova, A., Baldock, C., Simon, W.J., Gilroy, J., Baker, P.J., Stuitje, A.R., Rice, D.W., Slabas, A.R., Rafferty, J.B.> ;Structure. 2002 Jun
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