DavidRobertShprecherDO

PubMed

• Conjugal Synucleinopathies: A Clinicopathologic Study.
  Matthew Halverson, Nan Zhang, Geidy E Serrano, Christine M Belden, Kathy Long, Charles H Adler, Holly A Shill, Erika Driver-Dunckley, Shyamal H Mehta, Alireza Atri, Jo...> ;Movement Disorders. 2024 Apr 10
• Comorbid neurotrauma increases neurodegenerative-relevant cognitive, motor, and autonomic dysfunction in patients with REM sleep behavior disorder: A substudy of the N...
  Elliott, J., Ligman, B., Bryant-Ekstrand, M., Keil, A., Powers, K., Olivo, C., Neilson, L., Postuma, R., Pelletier, A., Gagnon, J., Gan-Or, Z., Yu, E., Liu, L., St Lou...> ;Sleep. 2024 Jan 5
• 2 citations
  Safety, tolerability, and efficacy of NLY01 in early untreated Parkinson's disease: a randomised, double-blind, placebo-controlled trial.
  McGarry, A., Rosanbalm, S., Leinonen, M., Olanow, C., To, D., Bell, A., Lee, D., Chang, J., Dubow, J., Dhall, R., Burdick, D., Parashos, S., Feuerstein, J., Quinn, J.,...> ;The Lancet. Neurology. 2024 Jan 1
• 1 citations
  Longitudinal motor decline in dementia with Lewy bodies, Parkinson disease dementia, and Alzheimer's dementia in a community autopsy cohort.
  Parichita Choudhury, Nan Zhang, Charles H Adler, Kewei Chen, Christine Belden, Erika Driver-Dunckley, Shyamal H Mehta, David R Shprecher, Geidy E Serrano, Holly A Shil...> ;Alzheimer's & Dementia. 2023 Oct 1
• 1 citations
  Adjusting for Underrepresentation Reveals Widespread Underestimation of Parkinson's Disease Symptom Burden.
  Ali G Hamedani, Peggy Auinger, Allison W Willis, Delaram Safarpour, David Shprecher, Natividad Stover, Thyagarajan Subramanian, Leslie Cloud> ;Movement Disorders. 2023 Sep 1
• 12 citations
  Baseline characteristics of the North American prodromal Synucleinopathy cohort.
  Jonathan E Elliott, Miranda M Lim, Allison T Keil, Ronald B Postuma, Amelie Pelletier, Jean-François Gagnon, Erik K St Louis, Leah K Forsberg, Julie A Fields, Daniel E...> ;Annals of Clinical and Translational Neurology. 2023 Apr 1
• 2 citations
  The Accuracy and Reliability of Sleep Staging and Sleep Biomarkers in Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder.
  Daniel J Levendowski, Thomas C Neylan, Joyce K Lee-Iannotti, Paul C Timm, Cyrus Guevarra, Elise Angel, David Shprecher, Gandis Mazeika, Christine M Walsh, Bradley F Bo...> ;Nature and Science of Sleep. 2023 Jan 1
• 5 citations
  Non-REM sleep with hypertonia in Parkinsonian Spectrum Disorders: A pilot investigation.
  Daniel J Levendowski, Christine M Walsh, Bradley F Boeve, Debby Tsuang, Joanne M Hamilton, David Salat, Chris Berka, Joyce K Lee-Iannotti, David Shprecher, Philip R We...> ;Sleep Medicine. 2022 Dec 1
• 12 citations
  Oral ENT-01 Targets Enteric Neurons to Treat Constipation in Parkinson Disease : A Randomized Controlled Trial.
  Michael Camilleri, Thyagarajan Subramanian, Fernando Pagan, Stuart Isaacson, Ramon Gil, Robert A Hauser, Mary Feldman, Mark Goldstein, Rajeev Kumar, Daniel Truong, Nis...> ;Annals of Internal Medicine. 2022 Dec 1
• 18 citations
  SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19.
  Geidy E Serrano, Jessica E Walker, Cécilia Tremblay, Ignazio S Piras, Matthew J Huentelman, Christine M Belden, Danielle Goldfarb, David Shprecher, Alireza Atri, Charl...> ;Journal of Neuropathology and Experimental Neurology. 2022 Aug 16
• 7 citations
  Treatment failure in persistent tic disorders: an expert clinicians' consensus-based definition.
  Davide Martino, Irene A. Malaty, Kirsten R. Müller-Vahl, Elaheh Nosratmirshekarlou, Tamara Pringsheim, David Shprecher, Christos Ganos> ;European Child & Adolescent Psychiatry. 2021 Nov 24
• 6 citations
  Clinical Practice Patterns in Tic Disorders Among Movement Disorder Society Members.
  Christos Ganos, Harini Sarva, Lille Kurvits, Donald L. Gilbert, Andreas Hartmann, Yulia Worbe, Pablo Mir, Kirsten R. Müller-Vahl, Alexander Münchau, David Shprecher, H...> ;Tremor and Other Hyperkinetic Movements. 2021 Oct 28
• 74 citations
  Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial
  Michael A. Schwarzschild, Alberto Ascherio, Cindy Casaceli, Gary C. Curhan, Rebecca Fitzgerald, Cornelia Kamp, Codrin Lungu, Eric A. Macklin, Kenneth Marek, Dariush Mo...> ;JAMA. 2021 Sep 14
• 14 citations
  Clinical Diagnostic Accuracy of Early/Advanced Parkinson Disease: An Updated Clinicopathologic Study.
  Charles H. Adler, Thomas G. Beach, Nan Zhang, Holly A. Shill, Erika Driver-Dunckley, Shyamal H. Mehta, Alireza Atri, John N. Caviness, Geidy E. Serrano, David Shpreche...> ;Neurology. Clinical Practice. 2021 Aug 1
• 2 citations
  Gene-Environment Interactions in Progressive Supranuclear Palsy.
  Irene Litvan, James A. Proudfoot, Eden R. Martin, David G. Standaert, David E. Riley, Deborah A. Hall, Connie Marras, Ece Bayram, Richard Dubinsky, Yvette Bordelon, St...> ;Frontiers in Neurology. 2021 Apr 9
• 51 citations
  Mapping of SARS-CoV-2 Brain Invasion and Histopathology in COVID-19 Disease
  Geidy E. Serrano, Jessica E. Walker, Richard Arce, Michael J. Glass, Daisy Vargas, Lucia I. Sue, Anthony Intorcia, Courtney M. Nelson, Javon Oliver, Jaclyn Papa, Aryck...> ;Medrxiv. 2021 Feb 18
• 6 citations
  Increased Risk of Autopsy-Proven Pneumonia with Sex, Season and Neurodegenerative Disease
  Thomas G. Beach, Aryck Russell, Lucia I. Sue, Anthony Intorcia, Michael J. Glass, Jessica E. Walker, Richard Arce, Courtney M. Nelson, Tony Hidalgo, Glenn Chiarolanza,...> ;Medrxiv. 2021 Jan 8
• 8 citations
  Understanding the relationship between freezing of gait and other progressive supranuclear palsy features.
  Saba Rezvanian, Irene Litvan, David G. Standaert, Joseph Jankovic, Stephen G. Reich, Deborah A. Hall, David Shprecher, Yvette Bordelon, Richard Dubinsky, Benzi M. Kluger> ;Parkinsonism & Related Disorders. 2020 Sep 1
• 2 citations
  Do Parkinson disease subject and caregiver-reported Epworth sleepiness scale reponses correlate?
  David Shprecher, Charles H. Adler, Nan Zhang, Holly A. Shill, Christine Belden, Erika Driver-Dunckley, Shyamal H. Mehta, Kathryn Davis, Lucia I. Sue, Edward Zamrini, T...> ;Clinical Neurology and Neurosurgery. 2020 Feb 6
• 21 citations
  Severe hyposmia distinguishes neuropathologically confirmed dementia with Lewy bodies from Alzheimer’s disease dementia
  Thomas G. Beach, Charles H. Adler, Nan Zhang, Geidy E. Serrano, Lucia I. Sue, Erika Driver-Dunckley, Shayamal H. Mehta, Edward Zamrini, Marwan N. Sabbagh, Holly A. Shi...> ;Plos One. 2020 Apr 22
• 2 citations
  Progressive Supranuclear Palsy and Statin Use
  Ece Bayram, Connie Marras, David G. Standaert, Benzi M. Kluger, Yvette Bordelon, David Shprecher, Irene Litvan> ;Movement Disorders. 2020 Jul 1
• 75 citations
  Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a c...
  Tanya Simuni, Liz Uribe, Hyunkeun Ryan Cho, Chelsea Caspell-Garcia, Christopher S. Coffey, Andrew Siderowf, John Q. Trojanowski, Leslie M. Shaw, John Seibyl, Andrew B....> ;The Lancet. Neurology. 2020 Jan 1
• 6 citations
  Prevalence of REM sleep behavior disorder in Sun City, Arizona.
  David Shprecher, Geidy E. Serrano, Nan Zhang, Anthony Intorcia, Kathryn Davis, Michael J. Glass, Jasmine Curry, Jessica E. Walker, Brett Cutler, Michael Callan, Angeli...> ;Heliyon. 2020 Jan 1
• 5 citations
  Cardiac sympathetic denervation and synucleinopathy in Alzheimer’s disease with brain Lewy body disease
  Geidy E. Serrano, David Shprecher, Michael Callan, Brett Cutler, Michael J. Glass, Nan Zhang, Jessica E. Walker, Anthony Intorcia, Charles H. Adler, Holly A. Shill, Er...> ;Brain Communications. 2020 Jan 1
• 16 citations
  Are the International Parkinson disease and Movement Disorder Society progressive supranuclear palsy (IPMDS-PSP) diagnostic criteria accurate enough to differentiate c...
  Ali Shoeibi, Irene Litvan, Jorge L. Juncos, Yvette Bordelon, David E. Riley, David G. Standaert, Stephen G. Reich, David Shprecher, Deborah A. Hall, Connie Marras, Ben...> ;Parkinsonism & Related Disorders. 2019 Dec 1
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Journal Articles

• Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial  
  Writing Group for the NINDS Exploratory Trials in Parkinson Disease (NET-PD)Investigators, Kieburtz K, Tilley BC, Elm JJ, et al, JAMA, 1/10/2015
• The RAB39B pG192R mutation causes X-linked dominant Parkinson's disease  
  Mata IF, Jang Y, Kim CH, Hanna DS, Dorschner MO, Samii A, Agarwal P, Roberts JW, Klepitskaya O, Shprecher DR, Chung KA, Factor SA, Espay AJ, Revilla FJ, Higgins DS, Li..., Mol Neurodegener, 1/1/2015
• Neurobehavioral aspects, pathophysiology, and management of Tourette's syndrome  
  Shprecher D, Schrock L, Himle M, Curr Opin Neurol, 1/1/2014
• Sustained remission of Parkinson disease associated melanoma with immunotherapy  
  Shprecher D, Grossmann K, Tward J, Parkinsonism Relat Disord, 1/1/2014
• Elucidating the mechanism of tic improvement in Tourette syndrome: a pilot study  
  Shprecher D, Gannon K, Agarwal N, Shi X, Anderson J, Tremor Other Hyperkinet Mov, 1/1/2014
• Temporal Course of the Tourette Syndrome Clinical Triad  
  Shprecher D, Rubenstein L, Gannon K, Frank S, Kurlan R, Tremor Other Hyperkinet Mov (NY), 1/1/2014
• Design innovations and baseline findings in a long-term Parkinson's trial: the National Institute of Neurological Disorders and Stroke Exploratory Trials in Parkinson'...  
  Elm JJ, NINDS NET-PD Investigators, Mov Disord, 1/27/2012
• Sensory Trick with Metoclopramide associated Tardive Tremor  
  Shprecher D, BMJ Case Rep, 1/1/2012
• Parkinson disease: the enteric nervous system spills its guts [Letter to the editor]  
  Shprecher DR, Derkinderen P, Neurology, 1/1/2012
• Willingness of Parkinson Disease Patients to Participate in Research Using Internet Based Technology  
  Shprecher D, Noyes Katia, Biglan Kevin, Wang Dongwen, Dorsey Ray E, Kurlan Roger, Adams Michael Jacob, Telemed J E Health, 1/1/2012
• Tourette’s Disorder [Review]  
  Lyon G, Shprecher D, Coffey B, Kurlan R, Curr Treat Options Neurol, 1/1/2010
• Normal pressure hydrocephalus: diagnosis and treatment [Review]  
  Shprecher D, Schwalb J, Kurlan R, Curr Neurol Neurosci Rep, 1/1/2008
• Willingness of Parkinson Disease Patients to Participate in Research Using Internet Based Technology.  
  Shprecher D, Noyes Katia, Biglan Kevin, Wang Dongwen, Dorsey Ray E, Kurlan Roger, Adams Michael Jacob, Telemed J E Health
• Sensory Trick with Metoclopramide associated Tardive Tremor.  
  Shprecher D, BMJ Case Rep
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Books/Book Chapters

• Treating Disruptive Disorders: A Guide to Psychological, Pharmacological, and Combined Therapies. 
  Chapter: Tourette Syndrome and Other Tic Disorders. 
  Hayes L, Himle M, Ramanujam K, Shprecher DEditors: Kapalka G.Routledge2015
• Uncommon Causes of Movement Disorders. 
  Chapter: Tics and Tourette syndrome. 
  Roger Kurlan and David ShprecherEditors: Nestor Galvez-Jiménez and Paul Tuite.Cambridge University Press2011
• The Encyclopedia of Movement Disorders. 
  Chapter: Complex tics. 
  Shprecher D, Kurlan REditors: Komploti K and Verhagen L.Elsevier2010
• The Encyclopedia of Movement Disorders. 
  Chapter: Simple tics. 
  Shprecher D, Kurlan REditors: Komploti K and Verhagen L.Elsevier2010
• Complextics. 
  Chapter: The Encyclopedia of Movement Disorders 
  Shprecher D, Kurlan REditors: Komploti K and Verhagen L.Elsevier
• Simple tics. 
  Chapter: The Encyclopedia of Movement Disorders 
  Shprecher D, Kurlan REditors: Komploti K and Verhagen L.Elsevier
• Tics and Tourette syndrome. 
  Chapter: Uncommon Causes of Movement Disorders 
  Roger Kurlan and David ShprecherEditors: Néstor Gálvez-Jiménez and Paul Tuite.Cambridge University Press
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Abstracts/Posters

• Visual Hallucinations and Visual Misperceptions in Parkinson's Disease: A Retrospective Chart Review.
  Kelsey Juster Switlyk MD, Greg Philips, David Shprecher DO, Edward Zamrini MD, Rodolfo Savica MD PhD, AAN 67th Annual Meeting, 1/18/2015
• Amantadine vs rimantadine in Parkinsonian disorders: A retrospective comparative tolerability study.
  Saminejad, B., Gannon, K., Zorn, M., Shprecher, D.R, Movement Disorders, 1/1/2015
• Neuroprotection trials in populations enriched for Parkinson disease risk.
  Shprecher DR, OHSU, Northwest Basal Ganglia Coterie, Victoria, British Columbia, Canada, 1/1/2014
• Understanding risk of parkinsonian disorders.
  D. Shprecher, J. Bautista, A. Davis, R. Savica, 18th International Congress of Parkinson Disease and Movement Disorders, 1/1/2014
• Colonoscopic screening for enteric nervous system pathology in Parkinson’s disease
  D.R. Shprecher, L. Huynh, P. Wall, S. Tripp, K. Boynton, J. Fang, J.B. Leverenz, J. Sonnen, 18th International Congress of Parkinson Disease and Movement Disorders, 1/1/2014
• Parkinson Disease Lesion Effect and Melanoma Treatment Response with Ipilimumab and Whole Brain Radiation.
  Shprecher D, Grossman K, Tward J, Movement Disorders, 1/1/2013
• Neuropsychiatric Side Effects of Cyclobenzaprine.
  Shprecher D, Sloan CT, Sederholm B, Movement Disorders, 1/1/2013
• Planning Clinical Trials in REM sleep behavior disorder.
  Shprecher DR, Northwest Basal Ganglia Coterie, OHSU, Seattle, WA, 1/1/2012
• HD Clinical Research.
  Shprecher DR, HDSA Huntington's Disease Education Day, Salt Lake City, UT, 1/1/2012
• 21st century neurology: towards preclinical diagnosis of Lewy body disorders.
  Shprecher DR, Pacific Northwest Basal Ganglia Coterie (OHSU), Hood River, OR, 1/1/2011
• A Clinical and Biomarker Discovery Initiative to Identify Individuals with Premotor Parkinson’s disease.
  Shprecher DR, Working Group on Clinical Trials, University of Rochester, 1/1/2009
• Copper Deficiency Myelopathy
  Shprecher DR, Unusual Diagnostic and Management Problems in Neuromuscular Disease, American Academy of Neurology, Boston, MA, 1/1/2007
• Age at remission in patients with Tourette syndrome.
  Rubenstein L, Shprecher D, Frank S, Kurlan R, Movement Disorders
• Identifying potential subjects for Tourette syndrome clinical research.
  Shprecher D, Rubenstein L, Wang D, Kurlan R, American Society for Experimental Therapeutics, Arlington, VA
• Dysphagia as a presenting symptom of progressive supranuclear palsy.
  Shprecher D and Evans R, Mov Disord
• Neuroimaging to elucidate the nature and mechanism of tic remission in Tourette syndrome using magnetic resonance imaging.
  Shprecher, D, Fitts, W, Agarwal, N, Shi, X, Prescott, A, Anderson, J, American Academy of Neurology
• Case Presentation: Copper Deficiency Myelopathy.
  Shprecher, D, Unusual Diagnostic and Management Problems in Neuromuscular Disease, American Academy of Neurology, Boston, MA
• Neurodevelopment of Dopamine Systems: Insights into the Pathogenesis of Tourette Syndrome.
  Shprecher D, 22nd Annual Symposium on Etiology, Pathogenesis, and Treatment of Parkinson’s Disease and Other Mov, Salt Lake City, UT
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Lectures

• Progress and Hope through Parkinson Disease Research. 
  Salt Lake City, UT - 1/1/2015
• Planning Neuroprotection Trials in Premanifest Lewy body disorders. 
  Scottsdale, AZ - 1/1/2015
• Hope through Parkinson Disease Research. 
  Logan, UT - 1/1/2014
• What does research mean to you? 
  Salt Lake City, UT - 1/1/2014
• Evaluation and Management of Parkinsonian Disorders 
  University of Utah, Salt Lake City, UT - 1/1/2014
• Neuroprevention Trials in Populations at-risk for Parkinson’s: are we there yet? 
  University of Utah, Salt Lake City, UT - 1/1/2014
• Understanding the Spectrum of Parkinsonian Disorders 
  University of Utah, Salt Lake City, UT - 1/1/2014
• Clinical Update on Pediatric Movement Disorders 
  Primary Children's Medical Center, Salt Lake City, UT - 1/1/2013
• Your Progress Report: What’s new in PD research? 
  Salt Lake City, UT - 1/1/2013
• Advancing Treatments for Parkinson’s Disease. 
  St. George, UT - 1/1/2013
• Clinical Update on Hyperkinetic Movement Disorders 
  University of Utah - 1/1/2013
• 21st Century PD Research: Where are We Headed? 
  Logan, UT - 1/1/2012
• Clinical Update On Management of Movement Disorders 
  University of Utah - 1/1/2012
• Avenging Dudley: On the Frontlines of Progressive Supranuclear Palsy Research 
  University of Utah - 1/1/2010
• Early Diagnosis and Treatment of Parkinson Disease 
  University of Utah - 1/1/2010
• Neurodevelopment of Dopamine Systems: Insights into the Pathogenesis of Tourette Syndrome 
  Salt Lake City, UT - 1/1/2008
• Delayed Leukoencephalopathy 
  University of Utah - 1/1/2006
• Event Organizer and lecturer, Annual Huntington Disease Education Symposium. 
  University of Utah, Salt Lake City, UT
• Movement Disorders Emergencies. 
  Western Intermountain Neurological Organization (WINO) Brainstorm Conference. Park City, UT
• Hope through PD Research at the University of Utah. 
  American Parkinson Disease Association, Ogden, UT
• Preclinical biomarkers of Parkinson disease. 
  University of Utah Brain Institute
• Delayed Leukoencephalopathy. 
  University of Utah
• Near Death Experiences and the Paradox of Consciousness 
  University of Utah
• Early Diagnosis and Treatment of Parkinson Disease. 
  University of Utah
• Avenging Dudley: On the frontlines of progressive supranuclear palsy research. 
  University of Utah
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