DebraJeskeZackMD

PubMed

• 40 citations
  Treatment of systemic lupus erythematosus patients with the BAFF antagonist "peptibody" blisibimod (AMG 623/A-623): results from randomized, double-blind phase 1a and ...
  William Stohl, Joan T. Merrill, R. John Looney, Jill P. Buyon, Daniel J. Wallace, Michael H. Weisman, Ellen M. Ginzler, Blaire Cooke, Donna Holloway, Arunan Kaliyaperu...> ;Arthritis Research & Therapy. 2015 Aug 20
• Response to: ‘Impact of gender on outcomes in ankylosing spondylitis’ by Feldtkeller et al
  Irene E. van der Horst-Bruinsma, Debra Zack, Annette Szumski, Andrew S Koenig> ;Annals of the Rheumatic Diseases. 2014 Jan 1
• 28 citations
  Comparison of Physician and Patient Global Assessments Over Time in Patients With Rheumatoid Arthritis A Retrospective Analysis From the RADIUS Cohort
  Joseph A. Markenson, Andrew S Koenig, Jing Yuan Feng, Sandeep Chaudhari, Debra Zack, David H. Collier, Arthur L. Weaver> ;Journal of Clinical Rheumatology. 2013 Sep 1
• 93 citations
  Female patients with ankylosing spondylitis: analysis of the impact of gender across treatment studies
  Irene E. van der Horst-Bruinsma, Debra Zack, Annette Szumski, Andrew S Koenig> ;Annals of the Rheumatic Diseases. 2013 Jul 1
• 18 citations
  Associations between inflammation, nocturnal back pain and fatigue in ankylosing spondylitis and improvements with etanercept therapy:
  Mohammed Hammoudeh, Debra Zack, Wenzhi Li, V Michelle Stewart, Andrew S Koenig> ;The Journal of International Medical Research. 2013 Jun 26
• 115 citations
  Comparison of health-related quality of life in rheumatoid arthritis, psoriatic arthritis and psoriasis and effects of etanercept treatment
  Vibeke Strand, Veronika Sharp, Andrew S Koenig, Grace S. Park, Yifei Shi, Brian Wang, Debra Zack, David Fiorentino> ;Annals of the Rheumatic Diseases. 2012 Jul 1
• 72 citations
  The relationship between joint damage and functional disability in rheumatoid arthritis: a systematic review
  Claire Bombardier, Marco Barbieri, Anju Parthan, Debra Zack, V. Walker, David Macarios, Josef S. Smolen> ;Annals of the Rheumatic Diseases. 2012 Jun 1
• 34 citations
  A novel modality of BAFF-specific inhibitor AMG623 peptibody reduces B-cell number and improves outcomes in murine models of autoimmune disease.
  Hailing Hsu, Sanjay D. Khare, Frances Lee, Kent Miner, YL Hu, Marina Stolina, Nessa Hawkins, Qing Chen, Shu-Yin Joanne Ho, Hosung Min, Fei Xiong, Tom Boone, Debra Zack> ;Clinical and Experimental Rheumatology. 2012 Mar 1
• 168 citations
  A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee
  Stanley Cohen, Susanna Proudman, Alan Kivitz, Francis X. Burch, John Paul Donohue, Deborah Burstein, Yu-Nien Sun, Christopher Banfield, Michael S. Vincent, Liyun Ni, D...> ;Arthritis Research & Therapy. 2011 Jul 29
• 75 citations
  Rodent Preclinical Models for Developing Novel Antiarthritic Molecules: Comparative Biology and Preferred Methods for Evaluating Efficacy
  Brad Bolon, Marina Stolina, Caroline King, Scot Middleton, Jill Gasser, Debra Zack, Ulrich Feige> ;Journal of Biomedicine & Biotechnology. 2011 Jan 1
• 19 citations
  A phase 2 randomized, double-blind study of AMG 108, a fully human monoclonal antibody to IL-1R, in patients with rheumatoid arthritis
  Mario H. Cardiel, Paul P. Tak, William G. Bensen, Francis X Burch, Šárka Forejtová, Janusz E Badurski, Tarundeep Kakkar, Terry Bevirt, Liyun Ni, Ellen McCroskery, Ange...> ;Arthritis Research & Therapy. 2010 Oct 15
• 33 citations
  Summary of worldwide pediatric malignancies reported after exposure to etanercept
  Peter McCroskery, Carol A. Wallace, Daniel J. Lovell, Scott Stryker, Nataliya Chernyukhin, Consuelo Blosch, Debra Zack> ;Pediatric Rheumatology Online Journal. 2010 Jun 14
• 68 citations
  RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TN...
  Marina Stolina, Georg Schett, Denise Dwyer, Steven Vonderfecht, Scot Middleton, Diane Duryea, Efrain Pacheco, Gwyneth Van, Brad Bolon, Ulrich Feige, Debra Zack, Paul J...> ;Arthritis Research & Therapy. 2009 Dec 11
• 52 citations
  Tumor Necrosis Factor α and RANKL Blockade Cannot Halt Bony Spur Formation in Experimental Inflammatory Arthritis
  Georg Schett, Marina Stolina, Denise Dwyer, Debra Zack, Stefan Uderhardt, Gerhard Krönke, Paul J. Kostenuik, Ulrich Feige> ;Arthritis and Rheumatism. 2009 Sep 1
• 8 citations
  Sample stability and variability of B-cell subsets in blood from healthy subjects and patients with systemic lupus erythematosus.
  Shelley Sims Belouski, Daniel J. Wallace, Michael H. Weisman, Mariko L. Ishimori, Lisa Hendricks, Debra Zack, Mike Vincent, Erik Rasmussen, John Ferbas, James B. Chung> ;Cytometry. Part B, Clinical Cytometry. 2009 Aug 10
• 62 citations
  The evolving systemic and local biomarker milieu at different stages of disease progression in rat adjuvant-induced arthritis.
  Marina Stolina, Brad Bolon, Scot Middleton, Denise Dwyer, Heather Brown, Diane Duryea, Li Zhu, Alison Rohner, James Pretorius, Paul J. Kostenuik, Ulrich Feige, Debra Zack> ;Journal of Clinical Immunology. 2009 Mar 1
• 18 citations
  The evolving systemic and local biomarker milieu at different stages of disease progression in rat collagen-induced arthritis
  Marina Stolina, Brad Bolon, Denise Dwyer, Scot Middleton, Diane Duryea, Paul J. Kostenuik, Ulrich Feige, Debra Zack> ;Biomarkers. 2008 Nov 1
• Therapeutic potential (1).
  Debra Zack, David A. Isenberg> ;Lupus. 2008 Mar 1
• 26 citations
  Structure-Based Design of Novel 2-Amino-6-phenyl-pyrimido[5′,4′:5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as Potent and Orally Active Inhibitors of Lymphocyte Specifi...
  Matthew W. Martin, John Newcomb, Joseph J. Nunes, Christina Boucher, Lilly Chai, Linda F. Epstein, Theodore Faust, Sylvia Flores, Paul Gallant, Anu Gore, Yan Gu, Faye ...> ;Journal of Medicinal Chemistry. 2008 Feb 16
• 50 citations
  Continuous RANKL inhibition in osteoprotegerin transgenic mice and rats suppresses bone resorption without impairing lymphorganogenesis or functional immune responses.
  Marina Stolina, Denise Dwyer, Michael S. Ominsky, Timothy J. Corbin, Gwyneth Van, Brad Bolon, Ildiko Sarosi, James M. McCabe, Debra Zack, Paul J. Kostenuik> ;Journal of Immunology. 2007 Dec 1
• 19 citations
  RANKL Inhibition: From Mice to Men (and Women)
  Marina Stolina, Paul J. Kostenuik, William C. Dougall, Lorraine A. Fitzpatrick, Debra Zack> ;Advances in Experimental Medicine and Biology. 2007 Jan 1
• 42 citations
  Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity
  Matthew W. Martin, John Newcomb, Joseph J. Nunes, David C. Mcgowan, Armistead David M, Christina Boucher, John L. Buchanan, William H. Buckner, Lilly Chai, Daniel Elba...> ;Journal of Medicinal Chemistry. 2006 Jul 7
• 79 citations
  RANKL is a Marker and Mediator of Local and Systemic Bone Loss in Two Rat Models of Inflammatory Arthritis
  Marina Stolina, Stephen Adamu, Michael S. Ominsky, Denise Dwyer, Frank Asuncion, Zhaopo Geng, Scot Middleton, Heather Brown, Jim Pretorius, Georg Schett, Brad Bolon, U...> ;Journal of Bone and Mineral Research. 2005 Oct 1
• 50 citations
  Additive bone‐protective effects of anabolic treatment when used in conjunction with RANKL and tumor necrosis factor inhibition in two rat arthritis models
  Georg Schett, Scot Middleton, Brad Bolon, Marina Stolina, Heather Brown, Li Zhu, Jim Pretorius, Debra Zack, Paul J. Kostenuik, Ulrich Feige> ;Arthritis and Rheumatism. 2005 May 1
• 8 citations
  Cell type specific targeted intracellular delivery into muscle of a monoclonal antibody that binds myosin IIb.
  Richard H. Weisbart, Fusheng Yang, Grace Chan, Rika Wakelin, Kevin Ferreri, Debra Jeske Zack, Brooke C. Harrison, Leslie A. Leinwand, Greg M. Cole> ;Molecular Immunology. 2003 Mar 1
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