DennisWNielsonMD

Pediatric Pulmonology • San Francisco, CA

Pediatric Asthma Pulmonology

Professor of Pediatrics

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Office
505 Parnassus Ave
San Francisco, CA 94143
Phone+1 415-476-2072

Fax+1 415-476-9278
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Education & Training

University of California (San Francisco)Residency, Pediatrics, 1976 - 1981
University of Utah School of MedicineClass of 1976
University of California (San Francisco)Fellowship, Pediatric Pulmonology

Certifications & Licensure

ID State Medical License 1995 - Present
CA State Medical License 1977 - 2023
UT State Medical License 1981 - 2020
OH State Medical License 1999 - 2002
American Board of Pediatrics Pediatrics

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2011-2014
Fellow (FAAP) American Academy of Pediatrics

Clinical Trials

Short Term Effects of Ivacaftor in Non-G551D Cystic Fibrosis Patients Start of enrollment: 2013 Oct 01
Completed
Not Applicable

Publications & Presentations

PubMed

9 citations
Early acquisition and conversion of Pseudomonas aeruginosa in Hispanic youth with cystic fibrosis in the United States
Meghan E. McGarry, Chiung Yu Huang, Dennis W. Nielson, Ngoc P. Ly> ;Journal of Cystic Fibrosis. 2021 May 1
16 citations
CFTR modulator therapy for cystic fibrosis caused by the rare c.3700A>G mutation.
Puay-Wah Phuan, Peter M. Haggie, Joseph Tan, Amber A. Rivera, Walter E. Finkbeiner, Dennis W. Nielson, Merlin Thomas, Ibrahim A. Janahi, Alan S. Verkman> ;Journal of Cystic Fibrosis. 2021 May 1
39 citations
Nanomolar-potency 'co-potentiator' therapy for cystic fibrosis caused by a defined subset of minimal function CFTR mutants
Puay-Wah Phuan, Joseph-Anthony Tan, Amber A. Rivera, Lorna Zlock, Dennis W. Nielson, Walter E. Finkbeiner, Peter M. Haggie, Alan S. Verkman> ;Scientific Reports. 2019 Nov 27
22 citations
Regional variations in longitudinal pulmonary function: A comparison of Hispanic and non‐Hispanic subjects with cystic fibrosis in the United States
Meghan E. McGarry, John Neuhaus, Dennis W. Nielson, Ngoc P. Ly> ;Pediatric Pulmonology. 2019 Sep 1
26 citations
Respiratory Medications in Infants <29 Weeks during the First Year Postdischarge: The Prematurity and Respiratory Outcomes Program (PROP) Consortium
Rita M. Ryan, Roberta L. Keller, Brenda B. Poindexter, Carl T. D'Angio, Pamela A. Shaw, Scarlett L. Bellamy, Paul E. Moore, Christopher McPherson, James M. Greenberg, ...> ;The Journal of Pediatrics. 2019 May 1
40 citations
Combination potentiator (‘co-potentiator’) therapy for CF caused by CFTR mutants, including N1303K, that are poorly responsive to single potentiators
Puay-Wah Phuan, Jung-Ho Son, Joseph-Anthony Tan, Clarabella J. Li, Ilaria Musante, Lorna Zlock, Dennis W. Nielson, Walter E. Finkbeiner, Mark J. Kurth, Luis J. V. Gali...> ;Journal of Cystic Fibrosis. 2018 Sep 1
32 citations
Pulmonary function disparities exist and persist in Hispanic patients with cystic fibrosis: A longitudinal analysis
Meghan E. McGarry, John Neuhaus, Dennis W. Nielson, Esteban G. Burchard, Ngoc P. Ly> ;Pediatric Pulmonology. 2017 Oct 30
132 citations
Bronchopulmonary Dysplasia and Perinatal Characteristics Predict 1-Year Respiratory Outcomes in Newborns Born at Extremely Low Gestational Age: A Prospective Cohort Study
Roberta L. Keller, Rui Feng, Sara B. DeMauro, Thomas W. Ferkol, William D. Hardie, Elizabeth E. Rogers, Timothy P. Stevens, Judith A. Voynow, Scarlett L. Bellamy, Pame...> ;The Journal of Pediatrics. 2017 Aug 1
41 citations
In vivo and in vitro ivacaftor response in cystic fibrosis patients with residual CFTR function: N-of-1 studies.
Meghan E. McGarry, Beate Illek, Ngoc P. Ly, Lorna Zlock, Sabrina Olshansky, Courtney Moreno, Walter E. Finkbeiner, Dennis W. Nielson> ;Pediatric Pulmonology. 2017 Jan 9
61 citations
Correctors and Potentiators Rescue Function of the Truncated W1282X-Cystic Fibrosis Transmembrane Regulator (CFTR) Translation Product.
Peter M. Haggie, Puay-Wah Phuan, Joseph-Anthony Tan, Haijin Xu, Radu G. Avramescu, Doranda Perdomo, Lorna Zlock, Dennis W. Nielson, Walter E. Finkbeiner, Gergely L. Lu...> ;The Journal of Biological Chemistry. 2017 Jan 20
39 citations
Forced Expiratory Volume in 1 Second Variability Helps Identify Patients with Cystic Fibrosis at Risk of Greater Loss of Lung Function
Wayne J. Morgan, Donald R. VanDevanter, David J. Pasta, Aimee J. Foreman, Jeffrey S. Wagener, Michael W. Konstan, Ted Liou, Susanna A. McColley, Ann McMullen, Alexandr...> ;The Journal of Pediatrics. 2016 Feb 1
42 citations
Improving transition from paediatric to adult cystic fibrosis care: programme implementation and evaluation
Megumi J. Okumura, Thida Ong, Diana Dawson, Dennis W. Nielson, Nancy Lewis, Martha Richards, Claire D. Brindis, Mary Ellen Kleinhenz> ;BMJ Quality & Safety. 2014 Jan 10
18 citations
Normalization of sweat chloride concentration and clinical improvement with ivacaftor in a patient with cystic fibrosis with mutation S549N.
Meghan E. McGarry, Dennis W. Nielson> ;Chest. 2013 Oct 1
31 citations
Novel CFTR variants identified during the first 3 years of cystic fibrosis newborn screening in California.
Lisa Prach, Ruth Koepke, Martin Kharrazi, Steven Keiles, Danieli Salinas, Maria Carmen Reyes, Mark Pian, Harry Opsimos, Kimberly N. Otsuka, Karen Hardy, Carlos Milla, ...> ;The Journal of Molecular Diagnostics. 2013 Sep 1
27 citations
Management of Plastic Bronchitis With Topical Tissue-type Plasminogen Activator
Elizabeth R. Gibb, Robert J. Blount, Nancy Lewis, Dennis W. Nielson, Gwynne D. Church, Kirk D. Jones, Ngoc P. Ly> ;Pediatrics. 2012 Aug 1
47 citations
Antibiotic Prescribing During Pediatric Ambulatory Care Visits for Asthma
Ian M. Paul, Judith H. Maselli, Adam L. Hersh, Homer A. Boushey, Dennis W. Nielson, Michael D. Cabana> ;Pediatrics. 2011 Jun 1
336 citations
Airway Microbiota and Pathogen Abundance in Age-Stratified Cystic Fibrosis Patients
Michael J. Cox, Martin Allgaier, Byron Taylor, Marshall S. Baek, Yvonne J. Huang, Rebecca A. Daly, Ulas Karaoz, Gary L. Andersen, Ronald T. Brown, Kei E. Fujimura, Bri...> ;Plos One. 2010 Jun 23
47 citations
Airway surface liquid depth measured in ex vivo fragments of pig and human trachea: dependence on Na+ and Cl− channel function
Yuanlin Song, Wan Namkung, Dennis W. Nielson, Jae-Woo Lee, Walter E. Finkbeiner, Alan S. Verkman> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2009 Dec 1
1 citations
Should inhaled beta-agonists or lung function testing be routine in prematurely born infants with chronic lung disease?
Brian Wu, Dennis W. Nielson> ;Pediatric Critical Care Medicine. 2008 Nov 1
71 citations
Glycosylation of sputum mucins is altered in cystic fibrosis patients.
Benjamin L. Schulz, Andrew John Sloane, Leanne J. Robinson, Sindhu S. Prasad, Robyn A. Lindner, Michael D. Robinson, Peter T. P. Bye, Dennis W. Nielson, Jenny L. Harry...> ;Glycobiology. 2007 Jul 1
41 citations
Hypertonic Saline Therapy in Cystic Fibrosis: EVIDENCE AGAINST THE PROPOSED MECHANISM INVOLVING AQUAPORINS *
Marc H. Levin, Shannon Sullivan, Dennis W. Nielson, Baoxue Yang, Walter E. Finkbeiner, Alan S. Verkman> ;The Journal of Biological Chemistry. 2006 Sep 1
133 citations
Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis.
Yuanlin Song, Danieli Salinas, Dennis W. Nielson, Alan S. Verkman> ;American Journal of Physiology. Cell Physiology. 2006 Mar 1
73 citations
Proteomic analysis of sputum from adults and children with cystic fibrosis and from control subjects.
Andrew John Sloane, Robyn A. Lindner, Sindhu S. Prasad, Lucille T. Sebastian, Susanne K. Pedersen, Michael D. Robinson, Peter T. P. Bye, Dennis W. Nielson, Jenny L. Harry> ;American Journal of Respiratory and Critical Care Medicine. 2005 Dec 1
66 citations
Submucosal gland dysfunction as a primary defect in cystic fibrosis
Danieli Salinas, Peter M. Haggie, Jay R. Thiagarajah, Yuanlin Song, Kristina W. Rosbe, Walter E. Finkbeiner, Dennis W. Nielson, Alan S. Verkman> ;FASEB Journal. 2005 Mar 1
36 citations
Identification of novel and rare mutations in California Hispanic and African American cystic fibrosis patients
Özgül M. Alper, Lee-Jun C. Wong, Suzanne Young, Michelle Pearl, Steve Graham, John E. Sherwin, Eliezer Nussbaum, Dennis W. Nielson, Arnold C. G. Platzker, Zoe Davies, ...> ;Human Mutation. 2004 Oct 1
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Grant Support

Core--Clinical ResourcesNational Institute Of Diabetes And Digestive And Kidney Diseases2005–2009
Relationship Between Family Function/Psychopathology/Cystic FibrosisNational Center For Research Resources1996–1997
Naloxone Reversal Of Endorphin-Mediated Respiratory Depression In SIDSNational Center For Research Resources1985