DonaldLeungMD

Allergy & Immunology • Denver, CO

Pediatric Asthma & Allergic Conditions, Clinical & Laboratory Immunology

Professor of Pediatrics, University Colorado

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Office
1400 Jackson St
Denver, CO 80206
Phone+1 303-388-4461
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Education & Training

Children's Hospital/Boston Medical CenterResidency, Pediatrics, 1977 - 1981
Boston University Medical CenterResidency, Allergy and Immunology, 1977 - 1979
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1977

Certifications & Licensure

CO State Medical License 1990 - 2025
American Board of Allergy and Immunology Allergy & Immunology
American Board of Allergy and Immunology Diagnostic Laboratory Immunology
American Board of Pediatrics Pediatrics

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 1993
Whos Who in Medicine and Healthcare Marquis Whos Who
Fellow (FAAAAI) American Academy of Allergy Asthma and Immunology

Clinical Trials

Cell Biology of Steroid Resistant Asthma Start of enrollment: 2006 Aug 01
Completed
Not Applicable
Effects of Pimecrolimus on Skin Biopsy Ex-plants From Patients With Atopic Dermatitis Start of enrollment: 2006 Sep 01
Completed
Immune Response to Varicella Vaccination in Children With Atopic Dermatitis Start of enrollment: 2005 Dec 01
Completed
Responses to Immunization With Keyhole Limpet Hemocyanin Administered by Scarification and the Intradermal Route Start of enrollment: 2007 Dec 01
Completed
Phase 1
The Underlying Mechanisms For S. Aureus Infection And Colonization Of Skin in People With Atopic Dermatitis With And Without Eczema Herpeticum (MRSA) Start of enrollment: 2009 Feb 01
Completed
Markers of Airway Inflammation in BAL Fluid From Children With Asthma Start of enrollment: 2007 Oct 01
Completed
Interferon Responses in Eczema Herpeticum Start of enrollment: 2011 Apr 01
Completed
Registry for the Atopic Dermatitis Research Network Start of enrollment: 2011 Aug 01
Completed
Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Pilot Start of enrollment: 2011 Nov 01
Completed
Early Phase 1
Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Study Start of enrollment: 2012 Oct 01
Completed
Not Applicable
Baked Egg or Egg Oral Immunotherapy for Children With Egg Allergy Start of enrollment: 2013 Jul 01
Completed
Phase 2
FiteBac Hand Sanitizer in the Management of Hand Dermatitis in Adults Start of enrollment: 2013 Sep 01
Completed
Not Applicable
ADRN Barrier/Immunoprofiling Exploratory Pilot Study Start of enrollment: 2014 Apr 01
Completed
Follow-up of the PEPITES Study to Evaluate Long-term Efficacy and Safety of Viaskin Peanut in Children Start of enrollment: 2017 Jan 23
Active, not recruiting
Phase 3
Targeted Microbiome Transplant in Atopic Dermatitis Start of enrollment: 2017 Sep 28
Completed
Phase 1, Phase 2
A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic Dermatitis Start of enrollment: 2017 Sep 21
Completed
Phase 1
Systems Biology of Early Atopy Start of enrollment: 2021 Mar 18
Recruiting
Impact of Increased Immunoglobulin E to Anti-herpes Simplex Virus -1 Innate Immune Responses in Atopic Dermatitis Patients With Eczema Herpeticum Start of enrollment: 2020 Jan 09
Recruiting
Roles: Sub-Investigator
The Role of Bacterial Toxins in Human Skin Disease Start of enrollment: 2019 Feb 20
Recruiting
Roles: Contact, Principal Investigator
Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis Start of enrollment: 2022 Nov 21
Recruiting
Phase 4
Roles: Study Chair, Principal Investigator
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Publications & Presentations

PubMed

How does pollution worsen allergies?
Myongsoon Sung, Byung Eui Kim, Donald Y M Leung> ;Annals of Allergy, Asthma & Immunology. 2024 Apr 1
The 80th anniversary of atopic dermatitis in the Annals of Allergy.
Donald Y M Leung> ;Annals of Allergy, Asthma & Immunology. 2024 Mar 1
1 citations
Omalizumab for the Treatment of Multiple Food Allergies.
Robert A Wood, Alkis Togias, Scott H Sicherer, Wayne G Shreffler, Edwin H Kim, Stacie M Jones, Donald Y M Leung, Brian P Vickery, J Andrew Bird, Jonathan M Spergel, Ah...> ;The New England Journal of Medicine. 2024 Mar 7
Evolving atopic dermatitis toward precision medicine.
Leung, D.> ;Annals of Allergy, Asthma & Immunology. 2024 Feb 1
Topical steroid withdrawal and atopic dermatitis.
Hannah F Marshall, Donald Y M Leung, Gideon Lack, Sayantani Sindher, Christina E Ciaccio, Susan Chan, Kari C Nadeau, Helen A Brough> ;Annals of Allergy, Asthma & Immunology. 2024 Apr 1
Air pollutants contribute to epithelial barrier dysfunction and allergic diseases.
Byung Eui Kim, Jessica W Hui-Beckman, Michael Zev Nevid, Elena Goleva, Donald Y M Leung> ;Annals of Allergy, Asthma & Immunology. 2024 Apr 1
History of S. aureus Skin Infection Significantly Associates with History of Eczema Herpeticum in Patients with Atopic Dermatitis.
Mary C Moran, Alanna Klose, Takeshi Yoshida, Anna De Benedetto, Lynda C Schneider, Peck Y Ong, Eric L Simpson, Donald Y M Leung, Benjamin L Miller, Christopher L Sepla...> ;Dermatology and Therapy. 2023 Oct 1
5 citations
The impact of temperature on the skin barrier and atopic dermatitis.
Jessica W Hui-Beckman, Elena Goleva, Donald Y M Leung, Byung Eui Kim> ;Annals of Allergy, Asthma & Immunology. 2023 Dec 1
1 citations
The SunBEAm birth cohort: Protocol design.
Corinne Keet, Scott H Sicherer, Supinda Bunyavanich, Cynthia Visness, Patricia C Fulkerson, Alkis Togias, Wendy Davidson, Susan Perry, Sanaz Hamrah, Agustin Calatroni,...> ;The Journal of Allergy and Clinical Immunology. Global. 2023 Aug 1
1 citations
Targeting type 2 immune activation beyond atopic dermatitis.
Donald Y M Leung, Paola Facheris, Karen A Veverka, Ferda Cevikbas, Emma Guttman-Yassky> ;Annals of Allergy, Asthma & Immunology. 2024 Feb 1
7 citations
Rapid reduction in Staphylococcus aureus in atopic dermatitis subjects following dupilumab treatment.
Eric L Simpson, Patrick M Schlievert, Takeshi Yoshida, Stephanie Lussier, Mark Boguniewicz, Tissa Hata, Zelma Fuxench, Anna De Benedetto, Peck Y Ong, Justin Ko, Agusti...> ;The Journal of Allergy and Clinical Immunology. 2023 Nov 1
3 citations
Phenotypic and Endotypic Determinants of Atopic Dermatitis Severity From the Atopic Dermatitis Research Network (ADRN) Registry.
Eric L Simpson, Anna De Benedetto, Mark Boguniewicz, Peck Y Ong, Stephanie Lussier, Miguel Villarreal, Lynda C Schneider, Amy S Paller, Emma Guttman-Yassky, Jon M Hani...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 Aug 1
5 citations
Dupilumab Inhibits Vascular Leakage of Blood Proteins Into Atopic Dermatitis Skin.
Donald Y M Leung, Robert Bissonnette, Simion Kreimer, Evgeny Berdyshev, Shantanu Bafna, Taras Lyubchenko, Brittany N Richers, Shannon Garcia, Marco Ramirez-Gama, Clift...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 May 1
1 citations
The association of residential distance from highly trafficked roads with atopic dermatitis risk.
Michael Z Nevid, Nathan Rabinovitch, James Crooks, Elena Goleva, Donald Leung, Jessica Hui> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 May 1
3 citations
Alterations of Epidermal Lipid Profiles and Skin Microbiome in Children With Atopic Dermatitis.
Jihyun Kim, Byung Eui Kim, Elena Goleva, Evgeny Berdyshev, Jaewoong Bae, Seokjin Kim, Hye-Young Kim, Un Ha Lee, Myoung Shin Kim, Minyoung Jung, Hyunmi Kim, Jinyoung Le...> ;Allergy, Asthma & Immunology Research. 2023 Mar 1
7 citations
Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T-cell responses in humans.
Daniel Lozano-Ojalvo, Scott R Tyler, Carlos J Aranda, Julie Wang, Scott Sicherer, Hugh A Sampson, Robert A Wood, A Wesley Burks, Stacie M Jones, Donald Y M Leung, Mari...> ;Allergy. 2023 Mar 1
8 citations
Stratum corneum lipid and cytokine biomarkers at age 2 months predict the future onset of atopic dermatitis.
Evgeny Berdyshev, Jihyun Kim, Byung Eui Kim, Elena Goleva, Taras Lyubchenko, Irina Bronova, Anna Sofia Bronoff, Olivia Xiao, Jiwon Kim, Sukyung Kim, Mijeong Kwon, Sung...> ;The Journal of Allergy and Clinical Immunology. 2023 May 1
5 citations
Targeting Skin Barrier Function in Atopic Dermatitis.
Ellen H van den Bogaard, Peter M Elias, Elena Goleva, Evgeny Berdyshev, Jos P H Smits, Simon G Danby, Michael J Cork, Donald Y M Leung> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 May 1
7 citations
The IL-4Rα Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice.
Barbara Yang, Hazel Wilkie, Mrinmoy Das, Maheshwor Timilshina, Wayne Bainter, Brian Woods, Michelle Daya, Meher P Boorgula, Rasika A Mathias, Peggy Lai, Carter R Petty...> ;The Journal of Allergy and Clinical Immunology. 2023 May 1
9 citations
Staphylococcus aureus causes aberrant epidermal lipid composition and skin barrier dysfunction.
Jihyun Kim, Byung Eui Kim, Evgeny Berdyshev, Irina Bronova, Lianghua Bin, Jaewoong Bae, Seokjin Kim, Hye-Young Kim, Un Ha Lee, Myoung Shin Kim, Hyunmi Kim, Jinyoung Le...> ;Allergy. 2023 May 1
1 citations
The diagnostic challenge of sesame allergy: A review of sesame oral food challenges in a pediatric clinic.
Michael Z Nevid, Donald Y M Leung, James L Crooks, Bruce J Lanser> ;Annals of Allergy, Asthma & Immunology. 2023 Jan 1
Topical steroid withdrawal syndrome: Should we worry?
Jonathan M Spergel, Donald Y M Leung> ;Annals of Allergy, Asthma & Immunology. 2023 Jan 1
3 citations
Safety, pharmacokinetics, and efficacy of ruxolitinib cream in children and adolescents with atopic dermatitis.
Donald Y M Leung, Amy S Paller, Andrea L Zaenglein, Wynnis L Tom, Peck Y Ong, May E Venturanza, Michael E Kuligowski, Qian Li, Xiaohua Gong, Mark S Lee> ;Annals of Allergy, Asthma & Immunology. 2023 Apr 1
5 citations
Epidermal differentiation complex genetic variation in atopic dermatitis and peanut allergy.
Michelle F Huffaker, Kanika Kanchan, Henry T Bahnson, Ingo Ruczinski, Gautam Shankar, Donald Y M Leung, Carolyn Baloh, George Du Toit, Gideon Lack, Gerald T Nepom, Ras...> ;The Journal of Allergy and Clinical Immunology. 2023 Apr 1
6 citations
Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens.
Elise G Liu, Biyan Zhang, Victoria Martin, John Anthonypillai, Magdalena Kraft, Alexander Grishin, Galina Grishina, Jason R Catanzaro, Sharon Chinthrajah, Tina Sindher...> ;Science Translational Medicine. 2022 Nov 16
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Press Mentions

National Jewish Health Researchers Discover Biomarkers That Could Predict Future Allergic ConditionsFebruary 23rd, 2023
Good Bacteria Fights Bad Bacteria in a Clinical TrialFebruary 26th, 2021
Study Shows How Compound in Breast Milk Fights Harmful BacteriaDecember 13th, 2019
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