DouglasRGalaskoMD

Professor, Neurosciences, UCSD School of Medicine Director of the UCSD Shiley-Marcos Alzheimer's Disease Research Center (ADRC).

Join to view full profile

Dr. Galasko is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Galasko's full profile

Already have an account?

Office
9350 Campus Point Dr
Perlman Ambulatory Care Center - Neurology
La Jolla, CA 92037
Phone+1 858-657-8540

Fax+1 858-657-8557
Is this information wrong?

Education & Training

Johns Hopkins UniversityResidency, Neurology, 1984 - 1987
Boston University Medical CenterInternship, Internal Medicine, 1983 - 1984
University of the WitwatersrandClass of 1979

Certifications & Licensure

CA State Medical License 1988 - 2024
MD State Medical License 1985 - 1988
American Board of Psychiatry and Neurology Neurology

Clinical Trials

Anti-Oxidant Treatment of Alzheimer's Disease Start of enrollment: 2006 Jan 01
Completed
Phase 1
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression Start of enrollment: 2010 Jun 01
Completed
Phase 2
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001 Start of enrollment: 2012 Dec 01
Recruiting
Phase 2, Phase 3
Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss Start of enrollment: 2014 Feb 28
Completed
Phase 3
Join now to see all

Publications & Presentations

PubMed

Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration.
Adam M Staffaroni, Annie L Clark, Jack C Taylor, Hilary W Heuer, Mark Sanderson-Cimino, Amy B Wise, Sreya Dhanam, Yann Cobigo, Amy Wolf, Masood Manoochehri, Leah Forsb...> ;JAMA Network Open. 2024 Apr 1
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease neuropathology.
Przemysław R Kac, Fernando González-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, ...> ;Nature Communications. 2024 Mar 23
A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) e...
Martin R Farlow, Brendan P Lucey, Lawrence S Honig, Donald Elbert, Randall Bateman, Jeremiah Momper, Ronald Thomas, Robert A Rissman, Judy Pa, Vahan Aslanyan, Archana ...> ;Medrxiv. 2024 Mar 22
Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies.
Christopher H Gibbons, Todd Levine, Charles Adler, Bailey Bellaire, Ningshan Wang, Jade Stohl, Pinky Agarwal, Georgina M Aldridge, Alexandru Barboi, Virgilio G H Evide...> ;JAMA. 2024 Mar 20
Lewy body dementia: Overcoming barriers and identifying solutions.
Kanishka Agarwal, Wendi Backler, Ece Bayram, Leah Bloom, Bradley F Boeve, Jang-Ho Cha, Maria Denslow, Tanis J Ferman, Douglas Galasko, James E Galvin, Stephen N Gomper...> ;Alzheimer's & Dementia. 2024 Mar 1
Association of Structural Forms of 17q21.31 with the Risk of Progressive Supranuclear Palsy andSub-haplotypes.
Hui Wang, Timothy S Chang, Beth A Dombroski, Po-Liang Cheng, Ya-Qin Si, Albert Tucci, Vishakha Patil, Leopoldo Valiente-Banuet, Kurt Farrell, Catriona Mclean, Laura Mo...> ;Medrxiv. 2024 Feb 28
Evaluation of ATNFramework and Biofluid Markers to Predict Cognitive Decline in Early Parkinson Disease.
Cousins, K., Irwin, D., Tropea, T., Rhodes, E., Phillips, J., Chen-Plotkin, A., Brumm, M., Coffey, C., Kang, J., Simuni, T., Foroud, T., Toga, A., Tanner, C., Kieburtz...> ;Neurology. 2024 Feb 1
1 citations
Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy.
Wang, H., Chang, T., Dombroski, B., Cheng, P., Patil, V., Valiente-Banuet, L., Farrell, K., Mclean, C., Molina-Porcel, L., Rajput, A., De Deyn, P., Bastard, N., Gearin...> ;Medrxiv. 2024 Jan 30
1 citations
Analysis of the longitudinal stability of human plasma miRNAs and implications for disease biomarkers.
Sandau, U., Wiedrick, J., McFarland, T., Fanning, Z., Saugstad, J., Galasko, D., Quinn, J.> ;Scientific Reports. 2024 Jan 25
Small RNA Changes in Plasma Have Potential for Early Diagnosis of Alzheimer's Disease before Symptom Onset.
Palade, J., Alsop, E., Courtright-Lim, A., Hsieh, M., Whitsett, T., Van Keuren-Jensen, K., Galasko, D.> ;Cells. 2024 Jan 23
Plasma p-tau212: antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease neuropathology.
Przemysław R Kac, Fernando González-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, ...> ;Medrxiv. 2023 Dec 11
Limitations of the human iPSC-derived neuron model for early-onset Alzheimer's disease.
Phoebe Valdes, Kenneth W Henry, Michael Q Fitzgerald, Koushik Muralidharan, Andrew B Caldwell, Srinivasan Ramachandran, Lawrence S B Goldstein, William C Mobley, Dougl...> ;Molecular Brain. 2023 Nov 3
1 citations
ATN cerebrospinal fluid biomarkers in dementia with Lewy bodies: Initial results from the United States Dementia with Lewy Bodies Consortium.
Lavanya Jain, Maria Khrestian, Shane Formica, Elizabeth D Tuason, Jagan A Pillai, Stephen Rao, Odinachi Oguh, Carol F Lippa, Oscar L Lopez, Sarah B Berman, Debby W Tsu...> ;Alzheimer's & Dementia. 2024 Jan 1
2 citations
The potential clinical value of plasma biomarkers in Alzheimer's disease.
Kaj Blennow, Douglas Galasko, Robert Perneczky, Frances-Catherine Quevenco, Wiesje M van der Flier, Akin Akinwonmi, Margherita Carboni, Alexander Jethwa, Ivonne Suridj...> ;Alzheimer's & Dementia. 2023 Dec 1
Assessments of the Utilities of CSF NPTX2 for Disease Progression in Cognitively Normal Individuals Who Progress to Clinical MCI and AD.
Leslie M Shaw, Douglas Galasko> ;Annals of Neurology. 2023 Oct 1
1 citations
Association Between Self- and Proxy-Reported Depression and Quality of Life in Mild-Moderate Alzheimer's Disease.
Elizabeth Joe, Freddi Segal-Gidan, Jeffrey L Cummings, Douglas Galasko, Sarah Tomaszewski Farias, David K Johnson, Leslie Ross, Kristine Yaffe, Xinhui Wang, Lon S Schn...> ;The American Journal of Geriatric Psychiatry. 2024 Jan 1
The MINT Sprint 2.0: A picture naming test for detection of naming impairments in Alzheimer's disease and in preclinical AD.
Tamar H Gollan, Dalia L Garcia, Alena Stasenko, Mayra Murillo, Chi Kim, Douglas Galasko, David P Salmon> ;Alzheimer's & Dementia. 2024 Jan 1
2 citations
Parkinson's Progression Markers Initiative: A Milestone-Based Strategy to Monitor Parkinson's Disease Progression.
Michael C Brumm, Andrew Siderowf, Tanya Simuni, Elliot Burghardt, Seung Ho Choi, Chelsea Caspell-Garcia, Lana M Chahine, Brit Mollenhauer, Tatiana Foroud, Douglas Gala...> ;Journal of Parkinson's Disease. 2023 Jan 1
3 citations
Alzheimer's Disease Pathology in Middle Aged and Older People with HIV: Comparisons with Non-HIV Controls on a Healthy Aging and Alzheimer's Disease Trajectory and Rel...
Erin E Sundermann, Laura M Campbell, Olivia Villers, Mark W Bondi, Ben Gouaux, David P Salmon, Douglas Galasko, Virawudh Soontornniyomkij, Ronald J Ellis, David J Moore> ;Viruses. 2023 Jun 4
3 citations
Tau seeds occur before earliest Alzheimer's changes and are prevalent across neurodegenerative diseases.
Matteo Manca, Heidi G Standke, Danielle F Browne, Mikayla L Huntley, Olivia R Thomas, Christina D Orrú, Andrew G Hughson, Yongya Kim, Jing Zhang, Curtis Tatsuoka, Xion...> ;Acta Neuropathologica. 2023 Jul 1
74 citations
Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study.
Andrew Siderowf, Luis Concha-Marambio, David-Erick Lafontant, Carly M Farris, Yihua Ma, Paula A Urenia, Hieu Nguyen, Roy N Alcalay, Lana M Chahine, Tatiana Foroud, Dou...> ;The Lancet. Neurology. 2023 May 1
Longitudinal head-to-head comparison ofC-PiB andF-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheim...
Charles D Chen, Austin McCullough, Brian Gordon, Nelly Joseph-Mathurin, Shaney Flores, Nicole S McKay, Diana A Hobbs, Russ Hornbeck, Anne M Fagan, Carlos Cruchaga, Ali...> ;European Journal of Nuclear Medicine and Molecular Imaging. 2023 Jul 1
4 citations
SCRN1: A cerebrospinal fluid biomarker correlating with tau in Alzheimer's disease.
Sophia Weiner, Mathias Sauer, Gunnar Brinkmalm, Julius Constantinescu, Radu Constantinescu, Bárbara Fernandes Gomes, Bruno Becker, Bengt Nellgård, Keti Dalla, Douglas ...> ;Alzheimer's & Dementia. 2023 Oct 1
3 citations
Comparison of the telephone-Montreal Cognitive Assessment (T-MoCA) and Telephone Interview for Cognitive Status (TICS) as screening tests for early Alzheimer's disease.
Sheridan D Chappelle, Christina Gigliotti, Gabriel C Léger, Guerry M Peavy, Diane M Jacobs, Sarah J Banks, Emily A Little, Douglas Galasko, David P Salmon> ;Alzheimer's & Dementia. 2023 Oct 1
51 citations
Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration.
Gonzalez-Ortiz, F., Turton, M., Kac, P., Smirnov, D., Premi, E., Ghidoni, R., Benussi, L., Cantoni, V., Saraceno, C., Rivolta, J., Ashton, N., Borroni, B., Galasko, D....> ;Brain. 2023 Mar 1
Join now to see all

Journal Articles

A Comprehensive Screening of Copy Number Variability in Dementia with Lewy Bodies
Eliezer Masliah, Ted Dawson, Nigel J Cairns, John C Morris, Sonja W Scholz, John Q Trojanowski, Liana Rosenthal, Lawrence S Honig, Douglas Galasko, Thomas G Beach, Ron..., ScienceDirect
Microstructural Brain Changes Track Cognitive Decline in Mild Cognitive Impairment
James B Brewer, Christina E Wierenga, Douglas Galasko, ScienceDirect

Lectures

14th International Conference on Alzheimer's Drug Discovery
Alzheimer's Drug Discovery Foundation, Jersey City, New Jersey - 9/9/2013

Press Mentions

New Biomarker Test Can Detect Alzheimer’s Neurodegeneration in the Blood – Neuroscience NewsDecember 29th, 2022
Test Detects Alzheimer’s Neurodegeneration in BloodDecember 28th, 2022
New Biomarker Test Can Detect Alzheimer’s Neurodegeneration in BloodDecember 27th, 2022
Join now to see all

Grant Support

Clinical Core BNational Institute On Aging2009–2012
Administrative Core ANational Institute On Aging2009–2012
Alzheimer'S Disease Research CenterNational Institute On Aging2007–2012
Clinical Studies Of Nsaidss As Y-Secretase Modulators In Alzheimer'S DiseaseNational Institute On Aging2009–2011
A Trial Of Ttp488 To Slow The Rate Of Clinical Progression Of Patients With ADNational Institute On Aging2006–2010
Testing The Role Of Axonal Transport Disturbance In AD?National Institute On Aging2007–2008
Biomarkers In Aging, MCI And Alzheimer'S DiseaseNational Institute On Aging2003–2007
Age Related Neurodegenerative Diseases In MicronesiaNational Institute On Aging2000–2006
Prevalence /Incidence /Risk Factors For Dementia On GuamNational Institute On Aging2002
Core--ClinicalNational Institute On Aging2002
Core---Administrative, Database, And StatisticalNational Institute On Aging2002
Clinical Evaluation Of Nsaids As Anti-Amyloid CompoundsNational Institute On Aging2002
A Phase 1B Study Of Ipa In ADNational Institute On Aging2001–2002