DungThiLeMD

Oncology • Baltimore, MD

Hematologic Oncology

Professor of Oncology, Johns Hopkins University School of Medicine

Join to view full profile

Dr. Le is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Le's full profile

Already have an account?

Office
401 N. Broadway
Baltimore, MD 21231
Phone+1 410-955-8893

Fax+1 410-614-8216
Is this information wrong?

Education & Training

Johns Hopkins UniversityFellowship, Hematology and Medical Oncology, 2004 - 2007
Johns Hopkins UniversityResidency, Internal Medicine, 2001 - 2004
Johns Hopkins University School of MedicineClass of 2001

Certifications & Licensure

PA State Medical License 2020 - 2024
MD State Medical License 2004 - 2024
NC State Medical License 2020 - 2022
OK State Medical License 2021 - 2021
ME State Medical License 2020 - 2021
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013-2014

Clinical Trials

Ipilimumab +/- Vaccine Therapy in Treating Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer Start of enrollment: 2009 Feb 01
Completed
Phase 1
QUILT-3.019: Phase 2 Study of NPC-1C Chimeric Monoclonal Antibody to Treat Pancreatic and Colorectal Cancer Start of enrollment: 2012 Jan 01
Completed
Phase 1, Phase 2
Safety and Efficacy of Combination Listeria/GVAX Immunotherapy in Pancreatic Cancer Start of enrollment: 2011 Sep 21
Completed
Phase 2
Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma Start of enrollment: 2013 Jan 01
Active, not recruiting
Phase 2
Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors (Cohorts A, B and C) Start of enrollment: 2013 Sep 01
Completed
Phase 2
FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer Start of enrollment: 2013 Nov 01
Completed
Phase 2
Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting Start of enrollment: 2014 Feb 05
Completed
Phase 2
Combination Study of Urelumab and Cetuximab in Patients With Advanced/Metastatic Colorectal Cancer or Advanced/Metastatic Head and Neck Cancer Start of enrollment: 2014 Apr 01
Completed
Phase 1
GVAX Pancreas Vaccine (With CY) and CRS-207 With or Without Nivolumab Start of enrollment: 2015 Jan 02
Completed
Phase 2
A Study of BMS-986249 Alone and in Combination With Nivolumab in Advanced Solid Tumors Start of enrollment: 2017 Dec 06
Active, not recruiting
Phase 1, Phase 2
Join now to see all

Publications & Presentations

PubMed

Nivolumab monotherapy or combination with ipilimumab with or without cobimetinib in previously treated patients with pancreatic adenocarcinoma (CheckMate 032).
Margaret Callahan, Asim Amin, Frederic J Kaye, Michael A Morse, Matthew H Taylor, Katriina J Peltola, Padmanee Sharma, Eileen M O'Reilly, Stephanie Meadows Shropshire,...> ;Journal for Immunotherapy of Cancer. 2024 Feb 5
Immunotherapy of MSI Cancer: Facts and Hopes.
H Catherine Wilbur, Dung T Le, Parul Agarwal> ;Clinical Cancer Research. 2024 Apr 15
Gemcitabine, Docetaxel, Capecitabine, Cisplatin, Irinotecan as First-line Treatment for Metastatic Pancreatic Cancer.
H Catherine Wilbur, Jennifer N Durham, Su Jin Lim, Katrina Purtell, Katherine M Bever, Daniel A Laheru, Ana De Jesus-Acosta, Nilofer S Azad, Bradley Wilt, Luis A Diaz,...> ;Cancer Research Communications. 2023 Aug 1
8 citations
A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectabl...
Thatcher Heumann, Carol Judkins, Keyu Li, Su Jin Lim, Jessica Hoare, Rose Parkinson, Haihui Cao, Tengyi Zhang, Jessica Gai, Betul Celiker, Qingfeng Zhu, Thomas McPhaul...> ;Nature Communications. 2023 Jun 20
5 citations
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of gastrointestinal cancer.
Kelly, R., Bever, K., Chao, J., Ciombor, K., Eng, C., Fakih, M., Goyal, L., Hubbard, J., Iyer, R., Kemberling, H., Krishnamurthi, S., Ku, G., Mordecai, M., Morris, V.,...> ;Journal for Immunotherapy of Cancer. 2023 Jun 1
11 citations
Pembrolizumab for previously treated, microsatellite instability-high/mismatch repair-deficient advanced colorectal cancer: final analysis of KEYNOTE-164.
Dung T Le, Luis A Diaz Jr, Tae Won Kim, Eric Van Cutsem, Ravit Geva, Dirk Jäger, Hiroki Hara, Matthew Burge, Bert H O'Neil, Petr Kavan, Takayuki Yoshino, Rosine Guimba...> ;European Journal of Cancer. 2023 Jun 1
Clinical outcomes of liposomal irinotecan in advanced pancreatic adenocarcinoma patients previously treated with conventional irinotecan-based chemotherapy: a real-wor...
Amol Gupta, Ana De Jesus-Acosta, Lei Zheng, Valerie Lee, Ihab Kamel, Dung Le, Michael Pishvaian, Daniel Laheru> ;Frontiers in Oncology. 2023 Jan 1
Colorectal cancer in patients of advanced age is associated with increased incidence ofp.V600E mutation and mismatch repair deficiency.
Eric S Christenson, Hua-Ling Tsai, Dung T Le, Elizabeth M Jaffee, Jonathan Dudley, Rena R Xian, Christopher D Gocke, James R Eshleman, Ming-Tseh Lin> ;Frontiers in Oncology. 2023 Jan 1
Solid Organ Transplantation Is Associated with an Increased Rate of Mismatch Repair Deficiency and PIK3CA Mutations in Colorectal Cancer.
Eric S Christenson, Valerie Lee, Hao Wang, Mark Yarchoan, Ana De Jesus-Acosta, Nilo Azad, Ahmet Gurakar, Ming-Tseh Lin, Dung T Le, Daniel C Brennan, Elizabeth M Jaffee...> ;Current Oncology. 2022 Dec 21
6 citations
Late-Onset Immunotherapy-Induced Myocarditis 2 Years After Checkpoint Inhibitor Initiation.
Andrew T Nguyen, Gerald J Berry, Ronald M Witteles, Dung T Le, Sean M Wu, George A Fisher, Han Zhu> ;JACC. Cardiooncology. 2022 Dec 1
5 citations
Pembrolizumab in Asian patients with microsatellite-instability-high/mismatch-repair-deficient colorectal cancer.
Takayuki Yoshino, Thierry Andre, Tae Won Kim, Wei Peng Yong, Kai-Keen Shiu, Benny Vittrup Jensen, Lars Henrik Jensen, Cornelis J A Punt, Denis Smith, Rocio Garcia-Carb...> ;Cancer Science. 2023 Mar 1
3 citations
Cell-free DNA Predicts Prolonged Response to Multi-agent Chemotherapy in Pancreatic Ductal Adenocarcinoma.
Eric S Christenson, Su Jin Lim, Jennifer Durham, Ana De Jesus-Acosta, Katherine Bever, Daniel Laheru, Amy Ryan, Parul Agarwal, Robert B Scharpf, Dung T Le, Hao Wang> ;Cancer Research Communications. 2022 Nov 1
2 citations
RAD51B Harbors Germline Mutations Associated With Pancreatic Ductal Adenocarcinoma.
Fanfan Xie, Ding Ding, Cong Lin, Dea Cunningham, Michael Wright, Ammar A Javed, Nilo Azad, Valerie Lee, Ross Donehower, Ana De Jesus-Acosta, Dung T Le, Michael Pishvai...> ;JCO Precision Oncology. 2022 Jun 1
215 citations
Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a rand...
Luis A Diaz Jr, Kai-Keen Shiu, Tae-Won Kim, Benny Vittrup Jensen, Lars Henrik Jensen, Cornelis Punt, Denis Smith, Rocio Garcia-Carbonero, Manuel Benavides, Peter Gibbs...> ;The Lancet. Oncology. 2022 May 1
8 citations
High local failure rates despite high margin-negative resection rates in a cohort of borderline resectable and locally advanced pancreatic cancer patients treated with...
Colin Hill, Shuchi Sehgal, Wei Fu, Chen Hu, Abhinav Reddy, Elizabeth Thompson, Amy Hacker-Prietz, Dung Le, Ana De Jesus-Acosta, Valerie Lee, Lei Zheng, Daniel A Laheru...> ;Cancer Medicine. 2022 Apr 1
9 citations
Neoadjuvant Stereotactic Body Radiotherapy After Upfront Chemotherapy Improves Pathologic Outcomes Compared With Chemotherapy Alone for Patients With Borderline Resect...
Colin S Hill, Lauren M Rosati, Chen Hu, Wei Fu, Shuchi Sehgal, Amy Hacker-Prietz, Christopher L Wolfgang, Matthew J Weiss, Richard A Burkhart, Ralph H Hruban, Ana De J...> ;Annals of Surgical Oncology. 2022 Apr 1
3 citations
Multiagent Chemotherapy and Stereotactic Body Radiation Therapy in Patients with Unresectable Pancreatic Adenocarcinoma: A Prospective Nonrandomized Controlled Trial.
Colin S Hill, Lauren Rosati, Hao Wang, Hua-Ling Tsai, Jin He, Amy Hacker-Prietz, Daniel A Laheru, Lei Zheng, Shuchi Sehgal, Vincent Bernard, Dung T Le, Timothy M Pawli...> ;Practical Radiation Oncology. 2022 Mar 17
83 citations
Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity.
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Cancer Cell. 2021 Jul 12
Corrigendum: Synthesis of 1,2-Dicarbonyl-3-enes by Hydroacylation of 1-Alkynes with Glyoxal Derivatives Using Metal-Organic Framework Cu/MOF-74 as Heterogeneous Catalyst.
Nguyen B. Nguyen, Giao H. Dang, Dung T. Le, Thanh N. Truong, Nam T. S. Phan> ;Chempluschem. 2021 Jul 1
Molecular characterization of bovine foamy virus and its association with bovine leukemia virus infection in Vietnamese cattle
Dung Thi Le, Son Vu Nguyen, Mari Okamoto, Nanako Yamashita-Kawanishi, Tung Duy Dao, Vuong Nghia Bui, Haruko Ogawa, Kunitoshi Imai, Takeshi Haga> ;The Journal of Veterinary Medical Science. 2021 Jun 28
6 citations
Anti-PD-1 elicits regression of undifferentiated pleomorphic sarcomas with UV-mutation signatures
Laurene S. Cheung, Lingling Chen, Teniola Oke, Thomas B. Schaffer, Karim Boudadi, Jillian T. Ngo, John Mc Mahon Gross, Holly Kemberling, Luis A. Diaz, Evan J. Lipson, ...> ;Journal for Immunotherapy of Cancer. 2021 Jun 1
77 citations
Health-related quality of life in patients with microsatellite instability-high or mismatch repair deficient metastatic colorectal cancer treated with first-line pembr...
Thierry André, Mayur Amonkar, Josephine M. Norquist, Kai Keen Shiu, Tae Won Kim, Benny Vittrup Jensen, Lars Henrik Jensen, Cornelis J. A. Punt, Denis Smith, Rocio Garc...> ;The Lancet. Oncology. 2021 May 1
13 citations
Strategic responses of the hotel sector to COVID-19: Toward a refined pandemic crisis management framework
Dung T. Le, Giang Thi Linh Phi> ;International Journal of Hospitality Management. 2021 Apr 1
26 citations
CD4 T Cell–Dependent Rejection of Beta-2 Microglobulin Null Mismatch Repair–Deficient Tumors
Giovanni Germano, Steve Lu, Giuseppe Rospo, Simona Lamba, Benoit Rousseau, Sonia Fanelli, Denise Stenech, Dung T. Le, John L. Hays, Maria Grazia Totaro, Vito Amodio, R...> ;Cancer Discovery. 2021 Mar 2
26 citations
Vaccine-Induced Intratumoral Lymphoid Aggregates Correlate with Survival Following Treatment with a Neoadjuvant and Adjuvant Vaccine in Patients with Resectable Pancre...
Lei Zheng, Ding Ding, Barish H. Edil, Carol Judkins, Jennifer N. Durham, Dwayne L. Thomas, Katherine M. Bever, Guanglan Mo, Sara Solt, Jessica Hoare, Raka Bhattacharya...> ;Clinical Cancer Research. 2021 Mar 1
Join now to see all

Lectures

KEYNOTE-164: Pembrolizumab for patients with advanced microsatellite instability high (MSI-H) colorectal cancer.
2018 ASCO Annual Meeting - Chicago, Illinois - 06/3/2018