EdwardC.HsiaoMD

PubMed

• Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone.
  Hsuan Lung, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun Kang, Sunita Ho, Kelly L Wentworth, Edward C Hsiao> ;JBMR Plus. 2024 May 1
• Immunologic Aspects in Fibrodysplasia Ossificans Progressiva.
  Anastasia Diolintzi, Mst Shaela Pervin, Edward C Hsiao> ;Biomolecules. 2024 Mar 16
• Intersections of Fibrodysplasia Ossificans Progressiva and Traumatic Heterotopic Ossification.
  Conan Juan, Alec C Bancroft, Ji Hae Choi, Johanna H Nunez, Chase A Pagani, Yen-Sheng Lin, Benjamin Levi, Edward C Hsiao> ;Biomolecules. 2024 Mar 14
• MMP-9 deficiency confers resilience in Fibrodysplasia Ossificans Progressiva in a man and mice.
  Vitali Lounev, Jay C Groppe, Niambi Brewer, Kelly L Wentworth, Victoria Smith, Meiqi Xu, Lutz Schomburg, Pankaj Bhargava, Mona Al Mukaddam, Edward C Hsiao, Eileen M Sh...> ;Journal of Bone and Mineral Research. 2024 Feb 16
• Study methodology and insights from the palovarotene clinical development program in fibrodysplasia ossificans progressiva.
  Robert J Pignolo, Mona Al Mukaddam, Geneviève Baujat, Matthew A Brown, Carmen De Cunto, Edward C Hsiao, Richard Keen, Kim-Hanh Le Quan Sang, Donna R Grogan, Rose Marin...> ;BMC Medical Research Methodology. 2023 Nov 13
• Frontal bone loss following coronal brow lift: A mimicker of head variant linear morphea.
  Maha Kazmi, William R Zhang, Edward Hsiao, Andrew Gross, Katie Grouse, Thomas M Link, Michael Tetzlaff, Philip Theodosopoulos, Anna Haemel> ;JAAD Case Reports. 2023 Nov 1
• A Case of Hypercalcemia from PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy.
  Isabella Niu, Edward C Hsiao, Rosanna Wustrack, John J Wysolmerski, Pamela Dann, Umesh Masharani> ;Calcified Tissue International. 2023 Aug 1
• Improving care pathways for people living with rare bone diseases (RBDs): outcomes from the first RBD Summit.
  Manju Chandran, Ines Alves, Thomas Carpenter, Michelle Davis, Edward C Hsiao, Anna Petryk, Jorg Oliver Semler, Marwan Sleiman> ;Osteoporosis International. 2023 Aug 1
• Most Fractures Treated Nonoperatively in Individuals With Fibrodysplasia Ossificans Progressiva Heal With a Paucity of Flareups, Heterotopic Ossification, and Loss of ...
  Carter M Lindborg, Mona Al Mukaddam, Genevieve Baujat, Tae-Joon Cho, Carmen L De Cunto, Patricia L R Delai, Elisabeth M W Eekhoff, Nobuhiko Haga, Edward C Hsiao, Rolf ...> ;Clinical Orthopaedics and Related Research. 2023 Dec 1
• Human iPSC-Derived Proinflammatory Macrophages cause Insulin Resistance in an Isogenic White Adipose Tissue Microphysiological System.
  Lin Qi, Koji Matsuo, Ashley Pereira, Yue Tung Lee, Fenmiao Zhong, Yuchen He, Peter-James H Zushin, Marko Gröger, Aditi Sharma, Holger Willenbring, Edward C Hsiao, Andr...> ;Small. 2023 Aug 1
• A follow-up report on the published paper Social and clinical impact of COVID-19 on patients with fibrodysplasia ossificans progressiva.
  Hayley Wallace, Rhonda H Lee, Edward C Hsiao> ;Orphanet Journal of Rare Diseases. 2023 Mar 20
• 10 citations
  Reduction of New Heterotopic Ossification (HO) in the Open-Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP).
  Robert J Pignolo, Edward C Hsiao, Mona Al Mukaddam, Geneviève Baujat, Staffan K Berglund, Matthew A Brown, Angela M Cheung, Carmen De Cunto, Patricia Delai, Nobuhiko H...> ;Journal of Bone and Mineral Research. 2023 Mar 1
• 12 citations
  Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery.
  Yeon-Suk Yang, Jung-Min Kim, Jun Xie, Sachin Chaugule, Chujiao Lin, Hong Ma, Edward Hsiao, Jaehyoung Hong, Hyonho Chun, Eileen M Shore, Frederick S Kaplan, Guangping G...> ;Nature Communications. 2022 Oct 19
• 1 citations
  Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans ...
  Kelly L Wentworth, Robert L Lalonde, Jay C Groppe, Niambi Brewer, Tania Moody, Steven Hansberry, Kimberly E Taylor, Eileen M Shore, Frederick S Kaplan, Robert J Pignol...> ;Journal of Bone and Mineral Research. 2022 Nov 1
• 7 citations
  The natural history of fibrodysplasia ossificans progressiva: A prospective, global 36-month study.
  Robert J Pignolo, Geneviève Baujat, Matthew A Brown, Carmen De Cunto, Edward C Hsiao, Richard Keen, Mona Al Mukaddam, Kim-Hanh Le Quan Sang, Amy Wilson, Rose Marino, A...> ;Genetics in Medicine. 2022 Dec 1
• 3 citations
  Identification of Risk Factors in the Development of Heterotopic Ossification After Primary Total Hip Arthroplasty.
  Sukhmani Singh, Saam Morshed, Daria Motamedi, Joseph Kidane, Alexandra Paul, Edward C Hsiao, Kelly L Wentworth> ;The Journal of Clinical Endocrinology and Metabolism. 2022 Aug 18
• 4 citations
  Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles.
  Elisabeth M W Eekhoff, Ruben D de Ruiter, Bernard J Smilde, Ton Schoenmaker, Teun J de Vries, Coen Netelenbos, Edward C Hsiao, Christiaan Scott, Nobuhiko Haga, Zvi Gru...> ;Human Gene Therapy. 2022 Aug 1
• 6 citations
  Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP): Results of a Randomized, Placebo-Controlled, Double-Blind Phase 2 Trial.
  Robert J Pignolo, Geneviève Baujat, Edward C Hsiao, Richard Keen, Amy Wilson, Jeff Packman, Andrew L Strahs, Donna R Grogan, Frederick S Kaplan> ;Journal of Bone and Mineral Research. 2022 Oct 1
• Corrigendum to "ACVR1extends inflammatory responses in human induced pluripotent stem cell-derived macrophages" [Bone. 153 2021 Dec; 116129. doi:10.1016/j.bone.2021.11...
  Koji Matsuo, Abigail Lepinski, Robert D Chavez, Emilie Barruet, Ashley Pereira, Tania A Moody, Amy N Ton, Aditi Sharma, Judith Hellman, Kiichiro Tomoda, Mary C Nakamur...> ;Bone. 2022 May 1
• 3 citations
  ACVR1-activating mutation causes neuropathic pain and sensory neuron hyperexcitability in humans.
  Xiaobing Yu, Amy N Ton, Zejun Niu, Blanca M Morales, Jiadong Chen, Joao Braz, Michael H Lai, Emilie Barruet, Hongju Liu, Kin Cheung, Syed Ali, Tea Chan, Katherine Biga...> ;Pain. 2023 Jan 1
• 1 citations
  Social and clinical impact of COVID-19 on patients with fibrodysplasia ossificans progressiva.
  Samuel Kou, Sammi Kile, Sai Samhith Kambampati, Evelyn C Brady, Hayley Wallace, Carlos M De Sousa, Kin Cheung, Lauren Dickey, Kelly L Wentworth, Edward C Hsiao> ;Orphanet Journal of Rare Diseases. 2022 Mar 4
• 4 citations
  Modeling the ACVR1R206H mutation in human skeletal muscle stem cells.
  Emilie Barruet, Steven M. Garcia, Jake Wu, Blanca M. Morales, Stanley Tamaki, Tania Moody, Jason H. Pomerantz, Edward C. Hsiao> ;Elife. 2021 Nov 10
• 6 citations
  Early outcomes and decision regret using PSMA/MRI guided focal boost for prostate cancer SBRT
  Thomas Eade, Andrew Kneebone, George Hruby, Jeremy T. Booth, Edward C. Hsiao, Andrew Le, Carol Kwong, John Atyeo, Chris Brown, Julia Hunter, Francina Wade> ;Practical Radiation Oncology. 2021 Oct 4
• 2 citations
  Social and Clinical Impact of COVID-19 on Patients with Fibrodysplasia Ossificans Progressiva
  Samuel Kou, Sammi Kile, Sai Samhith Kambampati, Evelyn C Brady, Hayley Wallace, Carlos M De Sousa, Kin Cheung, Lauren Dickey, Kelly L. Wentworth, Edward C. Hsiao> ;Research Square. 2021 Sep 16
• 24 citations
  Prevalence of fibrodysplasia ossificans progressiva (FOP) in the United States: estimate from three treatment centers and a patient organization.
  Robert J. Pignolo, Edward C. Hsiao, Geneviève Baujat, David Lapidus, Adam Sherman, Frederick S. Kaplan> ;Orphanet Journal of Rare Diseases. 2021 Aug 5
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