ElliottPVichinskyMD

Pediatric Hematology & Oncology • Oakland, CA

Medical Director, Hematology/Oncology Dept, Children's Hospital & Research Center Oakland

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Office
747 52nd St
Oakland, CA 94609
Phone+1 510-428-3651

Fax+1 510-450-5647
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Education & Training

U Washington Affil Hosps1976 - 1979
University of WashingtonResidency, Pediatrics, 1974 - 1976
State University of New York Downstate Medical Center College of MedicineClass of 1974, MD, CUM LAUDE ALPHA OMEGA ALPHA

Certifications & Licensure

CA State Medical License 1979 - 2026
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
Fellow (FAAP) American Academy of Pediatrics
Super Doctor SuperDoctors.com

Clinical Trials

Penicillin Prophylaxis in Sickle Cell Disease (PROPS) Start of enrollment: 1983 Aug 01
Completed
Phase 3
Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN) Start of enrollment: 2000 Jul 01
Completed
Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease Start of enrollment: 1999 Jun 01
Completed
Not Applicable
Combination Therapy Compared With Single-Drug Therapy in Patients With Cardiac Diseases Start of enrollment: 2005 Jun 01
Terminated
Phase 2
Priapism in Boys and Men With Sickle Cell Disease - Demographics, Characteristics and Prevalence Start of enrollment: 2005 Aug 01
Completed
ENTRUST, a 5 Year Surveillance of Children Aged 2 to <6 Years With Transfusional Iron Overload Treated With Deferasirox Start of enrollment: 2007 May 01
Completed
Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease Start of enrollment: 2004 Dec 01
Completed
Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study Start of enrollment: 2004 Dec 01
Completed
Phase 1
Assessment of Pain in People With Thalassemia Who Are Treated With Regular Blood Transfusions Start of enrollment: 2009 Jul 01
Completed
Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload Start of enrollment: 2007 Sep 01
Completed
Phase 2
Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension Start of enrollment: 2009 Mar 01
Completed
Phase 2
Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease Start of enrollment: 2009 Aug 01
Completed
Phase 2
Multi-Center Study of Iron Overload: Pilot Study Start of enrollment: 2009 Nov 01
Completed
A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia Start of enrollment: 2010 May 01
Completed
Phase 3
A 3-year, Prospective, Non-interventional, Multicenter Registry in Sickle Cell Disease (SCD) Patients Start of enrollment: 2010 Jan 01
Completed
Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease Start of enrollment: 2012 Feb 01
Completed
Phase 1, Phase 2
Efficacy and Safety Study of Deferiprone in Patients With Pantothenate Kinase-associated Neurodegeneration (PKAN) Start of enrollment: 2012 Dec 13
Completed
Phase 3
Multi-Center Study of Iron Overload: Survey Study (MCSIO) Start of enrollment: 2010 Mar 31
Completed
Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias Start of enrollment: 2014 Apr 17
Terminated
Phase 4
Phase II Study to Investigate the Benefits of an Improved Deferasirox Formulation (Film-coated Tablet) Start of enrollment: 2014 Jul 08
Completed
Phase 2
Long-term Deferiprone Treatment in Patients With Pantothenate Kinase-Associated Neurodegeneration Start of enrollment: 2014 Jun 01
Completed
Phase 3
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Publications & Presentations

PubMed

1 citations
Sickle Cell Disease Treatment with Arginine Therapy (STArT): study protocol for a phase 3 randomized controlled trial.
Chris A Rees, David C Brousseau, Daniel M Cohen, Anthony Villella, Carlton Dampier, Kathleen Brown, Andrew Campbell, Corrie E Chumpitazi, Gladstone Airewele, Todd Chan...> ;Trials. 2023 Aug 17
3 citations
COVID-19 Infection and Outcomes in Newborn Screening Cohorts of Sickle Cell Trait and Sickle Cell Disease in Michigan and Georgia.
Susan T Paulukonis, Angela Snyder, Matthew P Smeltzer, Ankit N Sutaria, Isabel Hurden, Krista Latta, Swathi Chennuri, Elliott Vichinsky, Sarah L Reeves> ;Journal of Pediatric Hematology/oncology. 2023 May 1
1 citations
Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia.
Farzana A Sayani, Sylvia T Singer, Katie T Carlberg, Elliott P Vichinsky> ;Hematology/oncology Clinics of North America. 2023 Apr 1
5 citations
The Clinical Phenotypes of Alpha Thalassemia.
Ashutosh Lal, Elliott Vichinsky> ;Hematology/oncology Clinics of North America. 2023 Apr 1
1 citations
Assessment of total and unbound cell-free heme in plasma of patients with sickle cell disease.
Madhav Vissa, Sandra K Larkin, Elliott P Vichinsky, Frans A Kuypers, Eric Soupene> ;Experimental Biology and Medicine. 2023 May 1
3 citations
The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: the UCSF registry.
Marisa E Schwab, Billie R Lianoglou, Dawn Gano, Juan Gonzalez Velez, Isabel E Allen, Regina Arvon, Ahmet Baschat, Diana W Bianchi, Melissa Bitanga, Anne Bourguignon, R...> ;Blood Advances. 2023 Jan 24
4 citations
Development of a Thalassemia International Prognostic Scoring System (TIPSS).
Angela Vitrano, Khaled M Musallam, Antonella Meloni, Mehran Karimi, Shahina Daar, Paolo Ricchi, Silvia Costantini, Efthymia Vlachaki, Vito Di Marco, Amal El-Beshlawy, ...> ;Blood Cells, Molecules & Diseases. 2023 Mar 1
Transitioning Adolescents With Sickle Cell Disease From Pediatric to Adult Care: Results From a New Survey of Health Care Professionals.
Nirmish R Shah, Marsha J Treadwell, Elliott Vichinsky> ;Journal of Pediatric Hematology/oncology. 2022 Oct 1
18 citations
Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in adults with non-transfusion dependent α-thalassaemia or β-thalassaemia: an open-label, multicen...
Kevin H M Kuo, D Mark Layton, Ashutosh Lal, Hanny Al-Samkari, Joy Bhatia, Penelope A Kosinski, Bo Tong, Megan Lynch, Katrin Uhlig, Elliott P Vichinsky> ;Lancet. 2022 Aug 13
1 citations
The effects of glutamine supplementation on markers of apoptosis and autophagy in sickle cell disease peripheral blood mononuclear cells.
Patrick B Walter, Leah S Hohman, Andrew Rokeby, Julian J Lum, Robert Hagar, Lisa Lavrisha, Augusta Saulys, Frans A Kuypers, Elliott Vichinsky, Claudia R Morris> ;Complementary Therapies in Medicine. 2022 Nov 1
2 citations
Implications for the metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: A pharmacokinetics study.
Claudia R Morris, Frans A Kuypers, Robert Hagar, Sandra Larkin, Lisa Lavrisha, Augusta Saulys, Elliott P Vichinsky, Jung H Suh> ;Complementary Therapies in Medicine. 2022 Mar 1
16 citations
Risk of mortality from anemia and iron overload in non-transfusion-dependent β-thalassemia.
Khaled M. Musallam, Angela Vitrano, Antonella Meloni, Sebastiano Addario Pollina, Mehran Karimi, Amal El-Beshlawy, Mahmoud Hajipour, Vito Di Marco, Saqib Hussain Ansar...> ;American Journal of Hematology. 2021 Dec 4
4 citations
An update on the US adult thalassaemia population: a report from the CDC thalassaemia treatment centres.
John Chapin, Alan R. Cohen, Ellis J. Neufeld, Elliott Vichinsky, Patricia J. Giardina, Jeanne Boudreaux, Binh C. Le, Kristy Kenney, Sean Trimble, Alexis A. Thompson> ;British Journal of Haematology. 2021 Nov 14
4 citations
Consensus statement for the perinatal management of patients with alpha thalassemia major.
Tippi C. MacKenzie, Ali Amid, Michael Angastiniotis, Craig Butler, Sandra Gilbert, Juan M. Gonzalez, Roberta L. Keller, Sandhya Kharbanda, Melanie Kirby-Allen, Barbara...> ;Blood Advances. 2021 Nov 8
2 citations
Anterior Pituitary Volume in Patients with Transfusion Dependent Anemias: Volumetric Approaches and Relation to Pituitary MRI‑R2.
Christoph Berliner, Zhiyue J. Wang, Sylvia T. Singer, Regine Grosse, Rosalie McDonough, Eric Padua, Qing Yuan, Marcela G Weyhmiller, Ellen James, Elliott Vichinsky, Ge...> ;Clinical Neuroradiology-klinische Neuroradiologie. 2021 Oct 28
8 citations
Primary HBB gene mutation severity and long-term outcomes in a global cohort of β-thalassaemia.
Khaled M. Musallam, Angela Vitrano, Antonella Meloni, Sebastiano Addario Pollina, Vito Di Marco, Saqib Hussain Ansari, Aldo Filosa, Paolo Ricchi, Adriana Ceci, Shahina...> ;British Journal of Haematology. 2021 Oct 25
15 citations
The transfusion management of beta thalassemia in the United States.
Ashutosh Lal, Trisha E. Wong, Sioban Keel, Monica B. Pagano, Jong Chung, Aditi Kamdar, Latha Rao, Alan Ikeda, Geetha Puthenveetil, Sanjay Shah, Jennifer C. Yu, Elliott...> ;Transfusion. 2021 Aug 28
6 citations
Time to rethink haemoglobin threshold guidelines in sickle cell disease.
Samir K. Ballas, Frans A. Kuypers, Victor R. Gordeuk, Jane S. Hankins, Alexis A. Thompson, Elliott Vichinsky> ;British Journal of Haematology. 2021 Jun 15
11 citations
Stable to improved cardiac and pulmonary function in children with high-risk sickle cell disease following haploidentical stem cell transplantation.
Deborah M. Friedman, Allen J. Dozor, Jordan Milner, Marise D'Souza, Julie-An Talano, Theodore B. Moore, Shalini Shenoy, Qiuhu Shi, Mark C. Walters, Elliott Vichinsky, ...> ;Bone Marrow Transplantation. 2021 May 6
51 citations
Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, pha...
Jo Howard, Kenneth I. Ataga, Robert Clark Brown, Maureen Achebe, Videlis Nduba, Amal El-Beshlawy, Hoda Hassab, Irene Agodoa, Margaret Tonda, Sarah Gray, Joshua Lehrer-...> ;The Lancet. Haematology. 2021 May 1
19 citations
Survival and causes of death in 2,033 patients with non-transfusion-dependent β-thalassemia
Khaled M. Musallam, Angela Vitrano, Antonella Meloni, Sebastiano Addario Pollina, Mehran Karimi, Amal El-Beshlawy, Mahmoud Hajipour, Vito Di Marco, Saqib Hussain Ansar...> ;Haematologica. 2021 Apr 22
8 citations
Voxelotor for the treatment of sickle cell disease.
Madhav Vissa, Elliott Vichinsky> ;Expert Review of Hematology. 2021 Mar 4
6 citations
A complication risk score to evaluate clinical severity of thalassaemia syndromes.
Angela Vitrano, Antonella Meloni, Walter Addario Pollina, Mehran Karimi, Amal El-Beshlawy, Mahmoud Hajipour, Vito Di Marco, Saqib Hussain Ansari, Aldo Filosa, Paolo Ri...> ;British Journal of Haematology. 2021 Feb 1
5 citations
Iron Deficiency: Implications Before Anemia.
Schuyler Tong, Elliott Vichinsky> ;Pediatrics in Review. 2021 Jan 1
4 citations
Pituitary iron and factors predictive of fertility status in transfusion dependent thalassemia.
Sylvia T. Singer, Roland Fischer, Isabel E. Allen, Ashutosh Lal, Elliott Vichinsky, Qing Yuan, Zhiyue J. Wang> ;Haematologica. 2020 Oct 29
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Journal Articles

Transfusion Practices and Complications in Thalassemia
Vinod V Balasa, Sanjay J Shah, Monica B Pagano, Geetha Puthenveetil, Jennifer Andrews, Ashutosh Lal, Trisha E Wong, Alan K Ikeda, Jong H Chung, Jennifer C Yu, Elliott ..., Transfusion
A Phase 3 Trial of L-glutamine in Sickle Cell Disease
Rita Bellevue, Joseph L Lasky, Elliott P Vichinsky, Lewis L Hsu, Sharada Sarnaik, Lynne D Neumayr, Yutaka Niihara, Sophie Lanzkron, Ifeyinwa Osunkwo, Lance Sieger, Edu..., The New England Journal of Medicine

Abstracts/Posters

Long-Term Clinical Outcomes of Lentiglobin Gene Therapy for Transfusion-Dependent _-Thalassemia in the Northstar (HGB-204) Study
Elliott P. Vichinsky, 61st Annual American Society of Hematology Meeting, 61st Annual American Society of Hematology Meeting - Orlando, FL, 12/9/2019
Development of a Severity Score System for Thalassemia Syndromes
Elliott P. Vichinsky, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Trends in Iron Overload over Past Two Decades: Results from the Natural History of Iron Burden Study with the SQUID BiosusceptometerClinically Relevant Abstract
Elliott Vichinsky, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/2019
Correlation of Voxelotor Exposure with Hemoglobin Response and Measures of Hemolysis in Patients from the HOPE Study
Elliott Vichinsky, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
A Pilot Adult Sickle Cell Hematology Clinic in CaliforniaÍs Inland Empire Improves Patient Outcome
Elliott P. Vichinsky, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Mitapivat (AG-348), an Oral PK-R Activator, in Adults with Non-Transfusion Dependent Thalassemia: A Phase 2, Open-Label, Multicenter Study in Progress
Elliott P. Vichinsky, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
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Lectures

Incidence of Vaso-Occlusive Crisis Does Not Increase with Achieving Higher Hemoglobin Levels on Voxelotor Treatment or after Discontinuation: Analyses of the HOPE Study
61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
Moving From Science Fiction to Clinical Reality: Gene Therapy for Beta-Hemoglobinopathies
61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
Significantly Improved Long Term Health Related Quality of Life (HRQL) and Neurocognition Following Familial Haploidentical Stem Cell Transplantation (HISCT) Utilizing...
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Clinical Outcomes of Lentiglobin Gene Therapy for Transfusion-Dependent β-Thalassemia Following Completion of the Northstar Hgb-204 Study
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Sickle Cell Disease Forum: Innovation in Drug Development and Emerging Science
60th American Society of Hematology Annual Meeting - 11/30/2018
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Other

Acute pain management in adults with sickle cell disease
Vichinsky EP, DeBaun MR
http://www.uptodate.com/contents/acute-pain-management-in-adults-with-sickle-cell-disease
UpToDate, Wolters Kluwer Health - 2012-05-01
Pregnancy in women with sickle cell disease
Vichinsky EP
http://www.uptodate.com/contents/pregnancy-in-women-with-sickle-cell-disease
UpToDate, Wolters Kluwer Health - 2012-12-13
Sickle cell trait
Vichinsky EP
http://www.uptodate.com/contents/sickle-cell-trait
UpToDate, Wolters Kluwer Health - 2013-03-26
Overview of the clinical manifestations of sickle cell disease
Vichinsky EP
http://www.uptodate.com/contents/overview-of-the-clinical-manifestations-of-sickle-cell-disease
UpToDate, Wolters Kluwer Health - 2012-11-16
Overview of the management of sickle cell disease
Vichinsky EP, Field JJ, DeBaun MR
http://www.uptodate.com/contents/overview-of-the-management-of-sickle-cell-disease
UpToDate, Wolters Kluwer Health - 2013-02-21
Variant sickle cell syndromes
Vichinsky EP
http://www.uptodate.com/contents/variant-sickle-cell-syndromes
UpToDate, Wolters Kluwer Health - 2012-03-07
Diagnosis of sickle cell syndromes
Vichinsky EP, Mahoney DH
http://www.uptodate.com/contents/diagnosis-of-sickle-cell-syndromes
UpToDate, Wolters Kluwer Health - 2012-07-24
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Press Mentions

Sickle Cell Math Is Brutally Simple, but Not Widely TaughtDecember 28th, 2021
CRISPR Gene-Editing Clinical Trial at UCSF Aims to Cure Deadly Blood DiseaseDecember 28th, 2021
Sickle Cell Gift Adds $2M to Oakland Hospital’s Growing ProgramDecember 16th, 2021
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Grant Support

Prevention Of Complications In ThalassemiaCenters For Disease Control And Prevention2007–2011
Modulation Of Iron Deposition In SCD And Other HemoglobinopathiesNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2010
Ninth Cooley'S Anemia SymposiumNational Heart, Lung, And Blood Institute2009
Thalassemia Clinical Research NetworkNational Heart, Lung, And Blood Institute2005–2009
Core--Patient ServiceNational Heart, Lung, And Blood Institute2005–2007
Core--Clinical Research 1National Heart, Lung, And Blood Institute2005–2007
Eighth Cooley'S Anemia SymposiumNational Heart, Lung, And Blood Institute2005
Neuropsych In SCDNational Center For Research Resources2005
Conrol Of Oxidant-Stress Induced Injury And Mitochrondrial Dysfunction By TRENational Center For Research Resources2005
Comparison Of Combination Therapy With Magnesium Pidoate And Hydroxyurea, VSNational Center For Research Resources2005
Natural History IronNational Center For Research Resources2004–2005
THAL OsteoNational Center For Research Resources2004
THALNational Center For Research Resources2004
Stop IINational Center For Research Resources2004
ParvovirusNational Center For Research Resources2004
Control Of Oxidant-Stress Induced Injury And Mitochrondrial Dysfunction By Tre...National Center For Research Resources2004
Comparison Of Combination Therapy With Magnesium Pidoate And Hydroxyurea, Vs....National Center For Research Resources2004
Secondary Hemochromatosis In Beta Thalassemia And SCDNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2004
California Thalassemia Clinical Research CenterNational Heart, Lung, And Blood Institute2000–2004
Randomized Trial For Core Decompression In Sickle Cell AnemiaNational Heart, Lung, And Blood Institute1998–2002
E/Beta Thalassemia--Natural History &Response To ChemoNational Heart, Lung, And Blood Institute1998–2002
Pathophysiology And Treatment In Sickle Cell Disease--Stroke Prevention TrialNational Center For Research Resources1998–2002
Pathophysiology And Treatment In Sickle Cell Disease--Pediatric HydroxyureaNational Center For Research Resources1998–2002
Cooperative Study Of Sickle Cell DiseaseNational Center For Research Resources1998–2002
Multicenter Study Of Hydroxyurea In Sickle Cell DiseaseNational Center For Research Resources2000
Avascular Necrosis Of The HIP In Sickle Cell DiseaseNational Center For Research Resources2000
Pediatric Cohort Of The CsscdDivision Of Blood Diseases And Resources1994–1998
Stroke Prevention Trial In Sickle Cell DiseaseNational Center For Research Resources1997
Pediatric HydroxyureaNational Center For Research Resources1997
Cooperative Study Of Sickle CellNational Center For Research Resources1997
Pathophysiology &Treatment Of Sickle Cell Anemia--Acute Chest StudyNational Center For Research Resources1996–1997
Pathophysiology &Treatment Of Sickle Cell Anemia--Stroke Prevention TrialNational Center For Research Resources1996
Pathophysiology &Treatment Of Sickle Cell Anemia--Pediatric HydroxyureaNational Center For Research Resources1996