EricChristopherKleerupMD

Pulmonology • Los Angeles, CA

Critical Care Medicine

Professor, Medicine, UCLA School of Medicine

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Office
757 Westwood Plz
Los Angeles, CA 90095
Phone+1 310-267-9643

Fax+1 818-989-6775
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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Pulmonary Disease and Critical Care Medicine, 1991 - 1994
UCLA-VA Greater Los AngelesResidency, Internal Medicine, 1988 - 1991
Washington University in St. Louis School of MedicineClass of 1988

Certifications & Licensure

CA State Medical License 1990 - 2025

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study
Unknown status
Phase 3
Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT) Start of enrollment: 2008 Mar 01
Withdrawn
Phase 4
Non-invasive Measures of Effects of Xolair in Asthma Start of enrollment: 2009 Feb 01
Terminated
Phase 4
Prevalence and Pathogenesis of Lung Disease in a Large HIV Cohort-coordinating Center Start of enrollment: 2009 Jan 01
Completed
Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography Start of enrollment: 2011 Jun 01
Unknown status
Phase 4
eRT Remote Health Monitoring Start of enrollment: 2012 Jan 01
Completed
Not Applicable
Study of COPD Subgroups and Biomarkers Start of enrollment: 2010 Nov 01
Active, not recruiting
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Publications & Presentations

PubMed

9 citations
Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures ...
Chunrui Zou, Frank Li, Jiwoong Choi, Babak Haghighi, Sanghun Choi, Prathish K Rajaraman, Alejandro P Comellas, John D Newell, Chang Hyun Lee, R Graham Barr, Eugene Ble...> ;International Journal of Chronic Obstructive Pulmonary Disease. 2021 May 31
22 citations
Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD: An Analysis of the SPIROMICS Cohort.
Robert M. Burkes, Agathe Ceppe, Claire M. Doerschuk, David Couper, Eric A. Hoffman, Alejandro P. Comellas, R. Graham Barr, Jerry A. Krishnan, Christopher B. Cooper, Wa...> ;Chest. 2020 Apr 1
29 citations
The Effects of Rare SERPINA1 Variants on Lung Function and Emphysema in SPIROMICS
Victor E. Ortega, Xingnan Li, Wanda K. O'Neal, Lela Lackey, Elizabeth J. Ampleford, Gregory A. Hawkins, Philip J. Grayeski, Alain Laederach, Igor Barjaktarevic, R. Gra...> ;American Journal of Respiratory and Critical Care Medicine. 2020 Mar 1
11 citations
Gene Expression Alterations in the Bronchial Epithelium of e-Cigarette Users
Sean Corbett, Matthew Nitzberg, Elizabeth Moses, Eric C. Kleerup, Teresa Wang, Catalina Perdomo, Claudia Perdomo, Gang Liu, Xiaohui Xiao, Hanqiao Liu, David Elashoff, ...> ;Chest. 2019 Oct 1
6 citations
Structural and Functional Features on Quantitative Chest Computed Tomography in the Korean Asian versus the White American Healthy Non-Smokers.
Hyun Bin Cho, Kum Ju Chae, Gong Yong Jin, Jiwoong Choi, Ching Long Lin, Eric A Hoffman, Sally E Wenzel, Mario Castro, Sean B Fain, Nizar N Jarjour, Mark L Schiebler, R...> ;Korean Journal of Radiology. 2019 Jul 1
11 citations
Lung Function, Coronary Artery Disease, and Mortality in HIV
Divay Chandra, Aman Gupta, Meghan Fitzpatrick, Sabina A. Haberlen, Maniraj Neupane, Joseph K. Leader, Lawrence A. Kingsley, Eric C. Kleerup, Matthew J. Budoff, Mallory...> ;Annals of the American Thoracic Society. 2019 May 31
13 citations
Safety and Tolerability of Comprehensive Research Bronchoscopy in Chronic Obstructive Pulmonary Disease. Results from the SPIROMICS Bronchoscopy Substudy.
J. Michael Wells, Douglas A. Arenberg, Igor Barjaktarevic, Surya P. Bhatt, Russell P. Bowler, Stephanie A. Christenson, David Couper, Mark T. Dransfield, MeiLan K. Han...> ;Annals of the American Thoracic Society. 2019 Apr 1
23 citations
Aspirin Use and Respiratory Morbidity in COPD: A Propensity Score-Matched Analysis in Subpopulations and Intermediate Outcome Measures in COPD Study
Ashraf Fawzy, Nirupama Putcha, Carrie P. Aaron, Russell P. Bowler, Alejandro P. Comellas, Christopher B. Cooper, Mark T. Dransfield, MeiLan K. Han, Eric A. Hoffman, Ri...> ;Chest. 2019 Mar 1
13 citations
Factors Associated With Progression of Lung Function Abnormalities in HIV-Infected Individuals.
Yijia Li, Seyed Mehdi Nouraie, Cathy Kessinger, Renee Weinman, Laurence Huang, Ruth M. Greenblatt, Eric C. Kleerup, Lawrence A. Kingsley, Deborah McMahon, Meghan Fitzp...> ;Journal of Acquired Immune Deficiency Syndromes. 2018 Dec 1
8 citations
Heterogeneous burden of lung disease in smokers with borderline airflow obstruction
Cheryl S. Pirozzi, Tian Gu, Pedro Miguel Quibrera, Elizabeth E. Carretta, MeiLan K. Han, Susan Murray, Christopher B. Cooper, Donald P. Tashkin, Eric C. Kleerup, Igor ...> ;Respiratory Research. 2018 Nov 20
16 citations
Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Stud...
Babak Haghighi, Sanghun Choi, Jiwoong Choi, Eric A. Hoffman, Alejandro P. Comellas, John D. Newell, R. Graham Barr, Eugene R. Bleecker, Christopher B. Cooper, David Co...> ;Respiratory Research. 2018 Sep 18
21 citations
Genome-wide association study of lung function and clinical implication in heavy smokers
Xingnan Li, Victor E. Ortega, Elizabeth J. Ampleford, R. Graham Barr, Stephanie A. Christenson, Christopher B. Cooper, David Couper, Mark T. Dransfield, MeiLan K. Han,...> ;BMC Medical Genetics. 2018 Aug 1
6 citations
Measuring associations between the microbiota and repeated measures of continuous clinical variables using a lasso-penalized generalized linear mixed model.
Laura Tipton, Karen T. Cuenco, Laurence Huang, Ruth M. Greenblatt, Eric C. Kleerup, Frank C. Sciurba, Steven R. Duncan, Michael P. Donahoe, Alison Morris, Elodie Ghedin> ;Biodata Mining. 2018 Jun 15
26 citations
Sleep disruption as a predictor of quality of life among patients in the subpopulations and intermediate outcome measures in COPD study (SPIROMICS).
Michelle Zeidler, Jennifer L. Martin, Eric C. Kleerup, Hartmut Schneider, Michael N. Mitchell, Nadia N. Hansel, Krishna M. Sundar, Helena Schotland, Robert C. Basner, ...> ;Sleep. 2018 May 1
41 citations
Decreased Lung Function and All-Cause Mortality in HIV-infected Individuals
Matthew R. Gingo, Mehdi Nouraie, Cathy Kessinger, Ruth M. Greenblatt, Laurence Huang, Eric C. Kleerup, Lawrence A. Kingsley, Deborah McMahon, Alison Morris> ;Annals of the American Thoracic Society. 2018 Feb 1
63 citations
Human airway branch variation and chronic obstructive pulmonary disease.
Benjamin M. Smith, Hussein Traboulsi, Austin Jhm, Ani Manichaikul, Eric A. Hoffman, Eugene R. Bleecker, Wellington V. Cardoso, Christopher B. Cooper, David Couper, Ste...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Jan 16
91 citations
Fungi stabilize connectivity in the lung and skin microbial ecosystems
Laura Tipton, Christian L. Müller, Zachary D. Kurtz, Laurence Huang, Eric C. Kleerup, Alison Morris, Richard Bonneau, Elodie Ghedin> ;Microbiome. 2018 Jan 15
9 citations
Tropheryma whipplei colonization in HIV-infected individuals is not associated with lung function or inflammation.
Shulin Qin, Emily Clausen, Seyed Mehdi Nouraie, Lawrence A. Kingsley, Deborah McMahon, Eric C. Kleerup, Laurence Huang, Elodie Ghedin, Ruth M. Greenblatt, Alison Morris> ;Plos One. 2018 Oct 4
137 citations
Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort.
Annette T. Hastie, Fernando J. Martinez, Jeffrey L. Curtis, Claire M. Doerschuk, Nadia N. Hansel, S. Christenson, Nirupama Putcha, Victor E. Ortega, Xingnan Li, R. Gra...> ;The Lancet. Respiratory Medicine. 2017 Dec 1
23 citations
Differentiation of quantitative CT imaging phenotypes in asthma versus COPD.
Sanghun Choi, Babak Haghighi, Jiwoong Choi, Eric A. Hoffman, Alejandro P. Comellas, John D. Newell, Sally E. Wenzel, Mario Castro, Sean B. Fain, Nizar N. Jarjour, Mark...> ;BMJ Open Respiratory Research. 2017 Nov 1
22 citations
Variability in objective and subjective measures affects baseline values in studies of patients with COPD.
Wayne Anderson, Jae Wook Ha, David Couper, Wanda K. O'Neal, R. Graham Barr, Eugene R. Bleecker, Elizabeth E. Carretta, Christopher B. Cooper, Claire M. Doerschuk, M. B...> ;Plos One. 2017 Sep 21
171 citations
Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort
MeiLan K. Han, Pedro Miguel Quibrera, Elizabeth E. Carretta, R. Graham Barr, Eugene R. Bleecker, Russell P. Bowler, Christopher B. Cooper, A.P. Comellas, David Couper,...> ;The Lancet. Respiratory Medicine. 2017 Aug 1
25 citations
Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis o...
Carlos H. Martinez, Susan Murray, R. Graham Barr, Eugene R. Bleecker, Russell P. Bowler, Stephanie A. Christenson, Alejandro P. Comellas, Christopher B. Cooper, David ...> ;Annals of the American Thoracic Society. 2017 May 1
17 citations
Assessment of coronary artery calcium by chest CT compared with EKG-gated cardiac CT in the multicenter AIDS cohort study.
Divay Chandra, Aman Gupta, Joseph K. Leader, Meghan Fitzpatrick, Lawrence A. Kingsley, Eric C. Kleerup, Sabina A. Haberlen, Matthew J. Budoff, Mallory D. Witt, Wendy S...> ;Plos One. 2017 Apr 28
6 citations
Evaluating small-airways disease in asthmatic patients: The utility of quantitative computed tomography
Donald P. Tashkin, Hyun J. Kim, Michelle Zeidler, Eric C. Kleerup, Jonathan G. Goldin> ;The Journal of Allergy and Clinical Immunology. 2017 Jan 1
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Press Mentions

UCLA Pulmonary Expert to Speak on Air Quality and WildfiresSeptember 11th, 2020
UCLA Expert Available for Interview on Wildfires' Impact on Air QualityOctober 29th, 2019
Lung Disease May Evade Diagnosis in Half of Heavy Smokers, Ex-SmokersMay 11th, 2016
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EricChristopherKleerupMD

Dr. Kleerup is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Clinical Trials

Publications & Presentations

Press Mentions

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