EricCSvenssonMDPhD, FACC, FAHA

Cardiology • Cambridge, MA

Adult Congenital Heart Disease

Director, Cardiovascular Translational Medicine, Novartis Institutes for Biomedical Research

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Office
220 Massachusetts Avenue
Cambridge, MA 02139
Phone+1 617-871-3108
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Education & Training

University of ChicagoFellowship, Cardiovascular Disease, 1995 - 2001
University of ChicagoResidency, Internal Medicine, 1993 - 1995
David Geffen School of Medicine at UCLAClass of 1993

Certifications & Licensure

IL State Medical License 1993 - 2023
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012
Elected Member The American Society for Clinical Investigation, 2009
Fellow (FACC) American College of Cardiology

Publications & Presentations

PubMed

92 citations
TET2-Driven Clonal Hematopoiesis and Response to Canakinumab: An Exploratory Analysis of the CANTOS Randomized Clinical Trial.
Eric C Svensson, Aviv Madar, Catarina D Campbell, Yunsheng He, Marc Sultan, Margaret L Healey, Huilei Xu, Katie D'Aco, Anita Fernandez, Clarisse Wache-Mainier, Peter L...> ;JAMA Cardiology. 2022 May 1
Coronary Artery Disease Polygenic Risk Score Identifies Patients at Higher Risk for Recurrent Cardiovascular Events in the CANTOS Trial.
Huilei Xu, Claudia Hon, Sergio Kaiser, Pablo Serrano-Fernandez, Nicole Hartmann, Denise Yates, Margaret L Healey, Arkady I Gusev, Jason M. Laramie, Scott Kennedy, Phil...> ;Circulation. Genomic and Precision Medicine. 2021 Oct 19
44 citations
Inhibition of IL1β by Canakinumab May Be Effective against Diverse Molecular Subtypes of Lung Cancer: An Exploratory Analysis of the CANTOS Trial.
Wong Connie C, Jason Baum, Angela Silvestro, Michael T. Beste, Bharani Bharani-Dharan, Siyan Xu, Ying A Wang, Xiaoshan Wang, Margaret F. Prescott, Lynne Krajkovich, Ma...> ;Cancer Research. 2020 Dec 15
8 citations
Ets1 Controls the Development of B Cell Autoimmune Responses in a Cell-Intrinsic Manner.
Alex Sunshine, David Goich, Alifa Stith, Katherine Sortino, Justin Dalton, Sarah Metcalfe, Eric C. Svensson, Lee Ann Garrett-Sinha> ;Immunohorizons. 2019 Jul 1
21 citations
Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling
Chih-Wei Chen, Christian Beyer, Jun Liu, Christiane Maier, Chun Li, Thuong Trinh-Minh, Xiaohan Xu, Stuart H Cole, Mindy H. Hsieh, Nicholas Ng, Alana Althage, Shelly Me...> ;Annals of the Rheumatic Diseases. 2017 Feb 2
72 citations
Arterial effects of canakinumab in patients with atherosclerosis and type 2 diabetes or glucose intolerance
Robin P. Choudhury, Jacqueline Birks, Venkatesh Mani, Luca Biasiolli, Matthew D. Robson, Philippe L. L’Allier, Marc-Alexandre Gingras, Nadia Alie, Mary Ann McLaughlin,...> ;Journal of the American College of Cardiology. 2016 Oct 18
65 citations
The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2
Erin C. Zook, Kevin Ramirez, Xiaohuan Guo, Grant van der Voort, Mikael Sigvardsson, Eric C. Svensson, Yang Xin Fu, Barbara L. Kee> ;The Journal of Experimental Medicine. 2016 May 2
38 citations
Particulate matter induces cardiac arrhythmias via dysregulation of carotid body sensitivity and cardiac sodium channels.
, , , , , , , , , , , , , , , > ;American Journal of Respiratory Cell and Molecular Biology. 2012 Dec 14
22 citations
FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development
Audrey S. Garnatz, Zhiguang Gao, Michael Broman, Spencer Martens, Judy U. Earley, Eric C. Svensson> ;Developmental Biology. 2011 Aug 1
6 citations
A double abdominal aorta with a double inferior vena cava: a human congenital vascular patterning defect.
Arda Kayhan, John Collins, Jafar Al-Sadir, Fang Zhu, Aytekin Oto, Eric C. Svensson> ;Birth Defects Research. Part A, Clinical and Molecular Teratology. 2011 Jun 1
34 citations
Cardiac-specific overexpression of dominant-negative CREB leads to increased mortality and mitochondrial dysfunction in female mice
Peter A. Watson, Nicholas Birdsey, Gordon S. Huggins, Eric C. Svensson, Daniel B. Heppe, Leslie A. Knaub> ;American Journal of Physiology. Heart and Circulatory Physiology. 2010 Dec 1
8 citations
Deciphering the Signals Specifying the Proepicardium
Eric C. Svensson> ;Circulation Research. 2010 Jun 25
38 citations
Myoferlin regulation by NFAT in muscle injury, regeneration and repair
Alexis R. Demonbreun, Karen A. Lapidos, Konstantina Heretis, Samantha Levin, Rodney M. Dale, Peter Pytel, Eric C. Svensson, Elizabeth M. McNally> ;Journal of Cell Science. 2010 Jul 15
309 citations
Epigenetic Attenuation of Mitochondrial Superoxide Dismutase 2 in Pulmonary Arterial Hypertension A Basis for Excessive Cell Proliferation and a New Therapeutic Target
Stephen L. Archer, Glenn Marsboom, Gene Kim, Hannah J. Zhang, Peter T. Toth, Eric C. Svensson, Jason R.B. Dyck, Mardi Gomberg-Maitland, Bernard Thébaud, Aliya N. Husai...> ;Circulation. 2010 Jun 22
54 citations
Ets1 is required for proper migration and differentiation of the cardiac neural crest
Zhiguang Gao, Gene Kim, Alexander C. Mackinnon, Alleda E. Flagg, Brett J. Bassett, Judy U. Earley, Eric C. Svensson> ;Development. 2010 May 1
110 citations
Epicardial–Myocardial Signaling Directing Coronary Vasculogenesis
Harold E. Olivey, Eric C. Svensson> ;Circulation Research. 2010 Mar 19
46 citations
FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesis.
Zhiguang Gao, Zan Huang, Harold E. Olivey, Sandeep Gurbuxani, John D. Crispino, Eric C. Svensson> ;The EMBO Journal. 2010 Jan 20
8 citations
Alternative promoter and GATA5 transcripts in mouse.
Bohao Chen, Elena Yates, Yong Huang, Paul Kogut, Lan Ma, Jerrold R. Turner, Yun Tao, Blanca Camoretti-Mercado, Deborah Lang, Eric C. Svensson, Joe G.N. Garcia, Peter J...> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2009 Sep 24
2 citations
Look who's talking: FGFs and BMPs in the proepicardium.
Eric C. Svensson> ;Circulation Research. 2009 Aug 28
41 citations
Translational Control of FOG-2 Expression in Cardiomyocytes by MicroRNA-130a
Gene Kim, Sadhana Samant, Judy U. Earley, Eric C. Svensson> ;Plos One. 2009 Jul 7
12 citations
Setting the Pace: Tbx3 and Tbx18 in Cardiac Conduction System Development
Elizabeth M. McNally, Eric C. Svensson> ;Circulation Research. 2009 Feb 13
11 citations
Increased FOG-2 in Failing Myocardium Disrupts Thyroid Hormone–Dependent SERCA2 Gene Transcription
Rosanne Rouf, Sarah Greytak, Eric C. Wooten, Jing Wu, Jay Boltax, Michael H. Picard, Eric C. Svensson, Wolfgang H. Dillmann, Richard D. Patten, Gordon S. Huggins> ;Circulation Research. 2008 Aug 29
39 citations
The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex.
Andrea E. Roche, Brett J. Bassett, Sadhana Samant, Wei Hong, Gerd A. Blobel, Eric C. Svensson> ;Journal of Molecular and Cellular Cardiology. 2008 Feb 1
6 citations
An alternative transcript of the FOG-2 gene encodes a FOG-2 isoform lacking the FOG repression motif.
Rodney M. Dale, Benjamin F. Remo, Eric C. Svensson> ;Biochemical and Biophysical Research Communications. 2007 Jun 8
18 citations
FOG-2 Attenuates Endothelial-to-Mesenchymal Transformation in the Endocardial Cushions of the Developing Heart
Alleda E. Flagg, Judy U. Earley, Eric C. Svensson> ;Developmental Biology. 2007 Apr 1
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