FrankYZhangMD

PubMed

• 14 citations
  CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells.
  Li Chen, Samantha Tang, Frank Zhang, Victor Garcia, John R. Falck, Michal L. Schwartzman, Ali S. Arbab, Austin M. Guo> ;American Journal of Physiology. Heart and Circulatory Physiology. 2019 Jun 1
• 7 citations
  Kidney dysfunction in the low-birth weight murine adult: implications of oxidative stress
  Wasan Abdulmahdi, May M. Rabadi, Edson Jules, Yara Marghani, Noor Marji, Jessica Leung, Frank Zhang, Avi Siani, Tamar Siskind, Kiara Vedovino, Nazrul Chowdhury, Mirosl...> ;American Journal of Physiology. Renal Physiology. 2018 Sep 1
• 19 citations
  Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation.
  Amanda Soler, Ian Hunter, Gregory Joseph, Rebecca Hutcheson, Brenda Hutcheson, Jenny Yang, Frank Zhang, Sachindra R. Joshi, Chastity Bradford, Katherine H. Gotlinger, ...> ;Journal of Molecular and Cellular Cardiology. 2018 Feb 8
• Corrigendum to "Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation" [J. Mol. Cell. Cardiol. 117 (2018) ...
  Amanda Soler, Ian Hunter, Gregory Joseph, Rebecca Hutcheson, Brenda Hutcheson, Jenny Yang, Frank Zhang, Sachindra R. Joshi, Chastity Bradford, Katherine H. Gotlinger, ...> ;Journal of Molecular and Cellular Cardiology. 2018 Apr 4
• 93 citations
  20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension.
  Victor Garcia, Ankit Gilani, Brian Shkolnik, Varunkumar Pandey, Frank Zhang, Rambabu Dakarapu, Shyam K. Gandham, N. Rami Reddy, Joan P. Graves, Artiom Gruzdev, Darryl ...> ;Circulation Research. 2017 Mar 21
• 18 citations
  Cardiovascular function in male and female JCR:LA-cp rats: Effect of high fat/high sucrose diet
  Ian Hunter, Amanda Soler, Gregory Joseph, Brenda Hutcheson, Chastity Bradford, Frank Zhang, Barry J. Potter, Spencer D. Proctor, Petra Rocic> ;American Journal of Physiology. Heart and Circulatory Physiology. 2017 Apr 1
• 10 citations
  The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.
  Varunkumar Pandey, Victor Garcia, Ankit Gilani, Priyanka Mishra, Frank Zhang, Mahesh P. Paudyal, John R. Falck, Alberto Nasjletti, Wen-Hui Wang, Michal L. Schwartzman> ;The Journal of Pharmacology and Experimental Therapeutics. 2017 Jan 1
• 20 citations
  20-HETE contributes to ischemia-induced angiogenesis.
  Li Chen, Gregory Joseph, Frank Zhang, Huyen Nguyen, Houli Jiang, Katherine H. Gotlinger, John R. Falck, Jing Yang, Michal L. Schwartzman, Austin M. Guo> ;Vascular Pharmacology. 2016 Aug 1
• 11 citations
  Androgen-sensitive hypertension associated with soluble guanylate cyclase-α1 deficiency is mediated by 20-HETE
  Ana C. Dordea, Sara Vandenwijngaert, Victor Garcia, Robert E. Tainsh, Daniel I. Nathan, Kaitlin Allen, Michael J. Raher, Laurel T. Tainsh, Frank Zhang, Wolfgang S. Lie...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2016 May 3
• 23 citations
  Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension
  Victor Garcia, Gregory Joseph, Brian Shkolnik, Yan Ding, Frank Zhang, Katherine H. Gotlinger, John R. Falck, Rambabu Dakarapu, Jorge H. Capdevila, Kenneth E. Bernstein...> ;American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 2015 Jul 1
• 19 citations
  Androgen-induced hypertension in angiotensinogen deficient mice: role of 20-HETE and EETS.
  Victor Garcia, Jennifer Cheng, Adam Weidenhammer, Yan Ding, Cheng-Chia Wu, Frank Zhang, Katherine H. Gotlinger, John R. Falck, Michal L. Schwartzman> ;Prostaglandins & Other Lipid Mediators. 2015 Jan 1
• Transgenic overproduction of omega-3 polyunsaturated fatty acids provides neuroprotection and enhances endogenous neurogenesis after stroke.
  Hu, X.,Zhang, F.,Leak, R. K.,Zhang, W.,Iwai, M.,Stetler, R. A.,Dai, Y.,Zhao, A.,Gao, Y.,Chen, J.> ;Curr. Mol. Med.. 2013 Aug 27
• 90 citations
  Endothelial Sirtuin 1 Deficiency Perpetrates Nephrosclerosis through Downregulation of Matrix Metalloproteinase-14: Relevance to Fibrosis of Vascular Senescence
  Radovan Vasko, Sandhya Xavier, Jun Chen, Chi Hua Sarah Lin, Brian B. Ratliff, May M. Rabadi, Julien Maizel, Rina Tanokuchi, Frank Zhang, Jian Cao, Michael S. Goligorsky> ;Journal of the American Society of Nephrology. 2014 Feb 1
• 22 citations
  20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension
  Yan Ding, Cheng-Chia Wu, Victor Garcia, Irina Dimitrova, Adam Weidenhammer, Gregory Joseph, Frank Zhang, Vijay L. Manthati, John R. Falck, Jorge H. Capdevila, Michal L...> ;American Journal of Physiology. Renal Physiology. 2013 Sep 1
• 17 citations
  Glutamine supplementation alleviates vasculopathy and corrects metabolic profile in an in vivo model of endothelial cell dysfunction.
  Francesco Addabbo, Qiuying Chen, Dhara Patel, May M. Rabadi, Brian B. Ratliff, Frank Zhang, Jean-Francois Jasmin, Michael S. Wolin, Michael P. Lisanti, Steven S. Gross...> ;Plos One. 2013 Jun 11
• 82 citations
  Tunneling nanotubes mediate rescue of prematurely senescent endothelial cells by endothelial progenitors: exchange of lysosomal pool.
  Kaoru Yasuda, Anupama Khandare, Leonid Burianovskyy, Shoichi Maruyama, Frank Zhang, Alberto Nasjletti, Michael S. Goligorsky> ;Aging. 2011 Jun 23
• 75 citations
  20-Hydroxy-5,8,11,14-eicosatetraenoic Acid Mediates Endothelial Dysfunction via IκB Kinase-Dependent Endothelial Nitric-Oxide Synthase Uncoupling
  Jennifer Cheng, Cheng-Chia Wu, Katherine H. Gotlinger, Frank Zhang, John R. Falck, Dubasi Narsimhaswamy, Michal L. Schwartzman> ;The Journal of Pharmacology and Experimental Therapeutics. 2010 Jan 1
• 36 citations
  Dual Pathways of Carbon Monoxide-Mediated Vasoregulation: Modulation by Redox Mechanisms
  Brian D. Lamon, Frank Zhang, Nitin Puri, Sergey V. Brodsky, Michael S. Goligorsky, Alberto Nasjletti> ;Circulation Research. 2009 Oct 9
• 38 citations
  Androgen-Dependent Hypertension Is Mediated by 20-Hydroxy-5,8,11,14-Eicosatetraenoic Acid–Induced Vascular Dysfunction: Role of Inhibitor of κB Kinase
  Cheng-Chia Wu, Jennifer Cheng, Frank Zhang, Katherine H. Gotlinger, Mukul Kelkar, Yilun Zhang, Jawahar L. Jat, John R. Falck, Michal L. Schwartzman> ;Hypertension. 2011 Apr 1
• 142 citations
  D-4F Induces Heme Oxygenase-1 and Extracellular Superoxide Dismutase, Decreases Endothelial Cell Sloughing, and Improves Vascular Reactivity in Rat Model of Diabetes
  Adam Kruger, Stephen J. Peterson, Saadet Turkseven, Pawel M. Kaminski, Frank Zhang, Shuo Quan, Michael S. Wolin, Nader G. Abraham> ;Circulation. 2005 Jun 14
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