GaryC.BrownMDMBA, Strategic Management

Retinal Disease

Professor of Ophthalmology, Jefferson Medical College, Philadelphia, PA Adj. Professor of Ophthalmology, Emory. University School of Medicine, Atlanta, GA

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Office
Center for Value Based Medicine
27 Wren Drive
Hilton Head, SC 29928
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Summary

Graduating from Colgate University in 1971, I received my MD from SUNY Upstate Medical Center in 1975. Interning in pediatrics at Grady Memorial Hospital in Atlanta, I had my ophthalmology residency, chief residency, and vitreoretinal fellowship at Wills Eye Hospital in Philadelphia. Board-certified in Ophthalmology in 1980, I received an MBA degree in Strategic Management from Saint Joseph’s University’s in 1998.

A practitioner at Wills and Professor of Ophthalmology at Jefferson Medical University, I was Director of the Retina Service at Wills from 2003-2012. I am currently Chief Medical Officer and Director of Pharmacoeconomics at the Center for Value-Based Medicine®, a healthcare economic research organization.

It has been my privilege to author 12 textbooks and over 700 writings on healthcare economics and vitreoretinal diseases. An investigator for multiple NIH clinical trials, I have had the privilege of giving over 450 lectures and am a reviewer for 40 peer-reviewed journals. Former President of the Pennsylvania Academy of Ophthalmology, the Philadelphia Ophthalmic Club, and the Wills Hospital Society, I was a founder and Co-chief Editor of the Lippincott’s Evidence-Based Ophthalmology.

Former Chairman of the Board of the Pennsylvania Physician Healthcare Plan, a PPO/HMO, and co-founder of the Value-Based Medicine concept, I am confident the latter’s patient/physician information systems will enhance U.S. medical care quality and cost-effectiveness.

It has been my good fortune to receive the American Academy of Ophthalmology Honor, Senior Honor and Lifetime Achievement Awards, the Arnall Patz Medal, Robert Shoemaker Award, and the Paul Craig Award. I have been honored to be in Who’s Who in the World, 1,000 Great Minds of the 21st Century, Who’s Who in America, Who’s Who in Medicine, Who’s Who Among Outstanding Business Executives, Top Ophthalmologists in the US, Philadelphia’s Top Doctors and Castle Connolly’s America’s Best Doctors.

Education & Training

Saint Josephs University Haub School of BusinessMBA, Strategic Management, 1996 - 1998
Saint Joseph's UniversityM.B.A., Strategic Management, 1996 - 1998
Sidney Kimmel Medical College at Thomas Jefferson University/Wills Eye HospitalFellowship, Surgical Retina and Vitreous, 1979 - 1981
Sidney Kimmel Medical College at Thomas Jefferson University/Wills Eye HospitalChief Residency, Ophthalmology, 1978 - 1979
Sidney Kimmel Medical College at Thomas Jefferson University/Wills Eye HospitalResidency, Ophthalmology, 1976 - 1979
Emory University School of MedicineInternship, Transitional Year, 1975 - 1976
SUNY Upstate Medical UniversityClass of 1975
Colgate UniversityB.S., Cum Laude, 1967 - 1971

Certifications & Licensure

SC State Medical License 2008 - 2025
PA State Medical License 1976 - 2024
NJ State Medical License 1981 - 2021
TX State Medical License 1997 - 2014
American Board of Ophthalmology Ophthalmology

Awards, Honors, & Recognition

Albert Nelson Lifetime Achievement Award Marquis Who's Who Organization, 2018-2019
Who's Who on the World Who's Who ORganization, 2018
Distinguished Alumnus Award Upstate Medical University, 2015
Philadelphia Magazine Castle Connolly, 1996-2015
America's Top Doctors Castle Connolly, 1996-2015
Super Doctors, 5% of Philadelphia Physicians 2013
1,000 Great Minds of the 21st Century American Biographical Institute, 2010
“A” rating in all categories Angie’s List Health, 2010
Life Achievement Honor Award American Academy of Ophthalmology, 2009
The Heritage Registry of Who’s Who 2008
Madison Who’s Who Among Executives and Professionals 2007-2008
International Award for the Advancement of Vitreoretinal Diseases Cambridge, 2006
Continental WHO'S WHO Registry of National Business Leaders 2006-2007
Who’s Who in Medicine and Healthcare 2006-2010
Marqui Who’s Who in America 2006-2010
Who’s Who in America 2005
Best Doctors in New Jersey 2005, 2007
Silver Tray Award for Distinguished Service Wills Eye Hospital Society, 2004
Arnall Patz Medal for Outstanding Contributions in the Field of Retinal Vascular Diseases Macula Society, 2003
Consumer’s Guide to Top Doctors 2003
Top Ophthalmologists in the United States 2003-2013
Main Line Top Doctor 2003
Guide to Top Doctors Center for the Study of Services (CSS), 2002
The National Registry of WHO’S WHO, Lifetime member 2001
Distinguished Service Award Pennsylvania Academy of Ophthalmology, 2000
Honored Life Member Ophthalmic Club of Philadelphia, 1999
Who’s Who Among Business Executives 1999
Strathmore’s WHO’S WHO 1999
Philadelphia’s Top Doctors for Seniors Philadelphia Magazine, 1998
Who’s Who in the World 1997, 2008-2010
Who’s Who Among Outstanding Business Executives 1996
Who’s Who in Medicine 1996-1997, 2004
America's Best Doctors (top 2-3% of doctors in the U.S., as elected by peers) Castle-Connolly, Ltd., 1996
Philadelphia’s Top Doctors Philadelphia Magazine, 1995-1997, 1999-2003, 2005-2013
Senior Honor Award American Academy of Ophthalmology, 1994
Paul Craig Award 1988
Honor Award American Academy of Ophthalmology, 1984
Resident Teaching Award Wills Eye Hospital, 1981-1982
Robert Shoemaker Award, Best paper presentation PA Academy of Ophthalmology, 1979
ARVO Scholarship Grant 1978
Mosby Scholarship Book Award 1974
Alpha Omega Alpha 1974
Phi Beta Kappa 1971
New York State Regents Medical Scholarship 1971
New York State Regents Scholarship 1967
Lifetime Achievement Award American Academy of Ophthalmology
Semifinalist. Mark Anderson & Gary Brown, authors, Tribunal, in Anything But Hollywood Screenplay Competition
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Publications & Presentations

PubMed

Cost-Utility Analysis of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration.
Gary C Brown, Melissa M Brown, Meg C Monigle> ;Ophthalmology. Retina. 2023 Nov 21
Prevention Surpasses Treatment: 5-year Follow-Up, Cost-Utility, and Cost-Benefit of Zeaxanthin Therapy for Neovascular Age-Related Macular Degeneration.
Gary C Brown, Melissa M Brown, Dennis Gierhart, R Joseph Olk> ;Ophthalmology and Therapy. 2023 Oct 1
1 citations
Preference-based comparison of quality of life associated with vision loss in Black and White ophthalmic populations in the US.
Gary C Brown, Melissa M Brown, Sanjay Sharma> ;Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie. 2024 Feb 1
Re: Le et al.: Associations between age-related eye diseases and Charles Bonnet Syndrome in participants of the Age-Related Eye Disease Study 2: Report Number 26 (Opht...
Gary C Brown, Robert P Murphy> ;Ophthalmology. 2022 Jun 1
1 citations
Quality of life associated with no light perception vision.
Gary C Brown, Melissa M Brown, Joshua D Stein, Sanjay Sharma> ;Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie. 2023 Aug 1
Value-based Medicine and Gene Therapy.
Gary C. Brown, Melissa M. Brown> ;International Ophthalmology Clinics. 2021 Jul 1
2 citations
Vision-related quality-of-life estimates in adolescent youths.
Woody Stevens, Gary C. Brown, Melissa M. Brown, Joshua D. Stein, Sanjay Sharma> ;Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie. 2021 Feb 13
9 citations
Opportunities to Reduce Potential Bias in Ophthalmic Cost-Utility Analysis.
Gary C. Brown, Melissa M. Brown, Imtiaz Chaudhry, Joshua D. Stein> ;JAMA Ophthalmology. 2021 Apr 1
10 citations
A Cost-Benefit Analysis of VEGF-Inhibitor Therapy for Neovascular Age-Related Macular Degeneration in the United States.
Gary C. Brown, Melissa M. Brown, Sara B. Rapuano, David S. Boyer> ;American Journal of Ophthalmology. 2021 Mar 1
19 citations
Cost-Utility Analysis of VEGF Inhibitors for Treating Neovascular Age-Related Macular Degeneration.
Gary C. Brown, Melissa M. Brown, Sara B. Rapuano, David S. Boyer> ;American Journal of Ophthalmology. 2020 Jun 19
1 citations
Reply to Comment on: Cost-Effectiveness of Limited Vitrectomy for Vision Degrading Myodesopsia
Benjamin Rostami, Jeannie Nguyen-Cuu, Gary C. Brown, Melissa A. Brown, Alfredo A. Sadun, Jerry Sebag> ;American Journal of Ophthalmology. 2020 May 1
3 citations
Vision utilities in Italy and the United States: Comparison of time tradeoff vision utilities.
Gabriella De Salvo, Gary C. Brown, Melissa M. Brown> ;European Journal of Ophthalmology. 2020 Mar 1
1 citations
Economic Evaluation of Anti-Vascular Endothelial Growth Factor Therapy for Wet Age-Related Macular Degeneration.
Melissa M. Brown, Gary C. Brown> ;JAMA Ophthalmology. 2020 Jan 1
Re: Hughes et al.: Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with juvenile idiopathic arthritis (Ophthalmology. 2019;126:415-424).
Gary C. Brown, Melissa M. Brown> ;Ophthalmology. 2019 Oct 1
5 citations
Cost-Effectiveness of Limited Vitrectomy for Vision-Degrading Myodesopsia.
Benjamin Rostami, Jeannie Nguyen-Cuu, Gary Brown, Melissa Brown, Alfredo A Sadun, J Sebag> ;American Journal of Ophthalmology. 2019 Aug 1
5 citations
Ethnicity and Diabetic Quality-of-Life.
Gary C. Brown, Melissa M. Brown, Sanjay Sharma> ;The American Journal of the Medical Sciences. 2019 Aug 1
19 citations
Cost-utility analysis of cataract surgery in the United States for the year 2018.
Gary C. Brown, Melissa M. Brown, Brandon G. Busbee> ;Journal of Cataract and Refractive Surgery. 2019 Jul 1
7 citations
Patient Preference-Based Comparative Effectiveness and Cost-Utility Analysis of the Prostamides for Open-Angle Glaucoma.
Gary C. Brown, Melissa M. Brown> ;Journal of Ocular Pharmacology and Therapeutics. 2019 Apr 6
6 citations
Health care stakeholder perceptions of vision loss.
Gary C. Brown, Melissa M. Brown> ;Survey of Ophthalmology. 2019 May 1
26 citations
Vision-Related Quality of Life Associated with Unilateral and Bilateral Ocular Conditions.
Gary C. Brown, Melissa M. Brown, Joshua D. Stein, William E. Smiddy, Lynn Geiger, Heidi B. Lieske, Philip A. Lieske, Sanjay Sharma, Woody Stevens> ;Ophthalmology. 2018 Feb 21
11 citations
The Burden of Retinal Venous Occlusion: An Assessment of Fellow Eyes in 1000 Cases.
Gary C. Brown, Janet Yoo, Melissa A. Brown, Adam Turpcu, Yamina Rajput, William E. Benson, Mitchell S. Fineman, David H. Fischer, Sunir J. Garg, Omesh P. Gupta, Allen ...> ;Ophthalmology. Retina. 2017 Sep 1
Cost-Utility of Evaluation for Posterior Vitreous Detachment and Prophylaxis of Retinal Detachment
Gary C. Brown, Jonathan S. Chang> ;Ophthalmology.
9 citations
The comparative effectiveness and cost-effectiveness of ranibizumab for neovascular macular degeneration revisited.
Gary C. Brown, Melissa M. Brown, Heidi B. Lieske, Adam Turpcu, Yamina Rajput> ;International Journal of Retina and Vitreous. 2017 Feb 13
5 citations
RUPTURED RETINAL ARTERIAL MACROANEURYSM ON THE OPTIC DISK.
Ehsan Rahimy, Brian C. Doyle, Gary C. Brown> ;Retinal Cases & Brief Reports. 2017 Jan 1
37 citations
SOCIETAL COSTS ASSOCIATED WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION IN THE UNITED STATES.
Melissa M. Brown, Gary C. Brown, Heidi B. Lieske, Irwin Tran, Adam Turpcu, Shoshana Colman> ;Retina. 2016 Feb 1
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Journal Articles

Update on Value-Based MedicineC
Brown MM. Brown GC, Curr Opin Ophthalmol, 5/1/2013
Vascular crossing patterns in patients with systemic arterial hypertension
Waisbren E, Salz DA Brown GC, Brown MM, Br J Ophthalmol, 4/13/2013
Serous macular detachment in waldenström macroglobulinemia: a report of four cases
Baker PS, Garg SJ, Fineman MS, Chiang A, Alshareef RA, Belmont J, Brown GC, Am J Ophthalmol., 1/1/2013
Cataract surgery cost-utility revisited in 2012 A new economic paradigm
Brown GC, Brown MM, Menezes A, Busbee BG, Lieske HB, Lieske PA, Ophthalmology, 1/1/2013
Interventions for Toxoplasma Retinochoroiditis: A Report by the American Academy of Ophthalmology
Kim SJ, Scott IU, Brown GC, Brown MM, Ho AC, Ip MS, Recchia FM, Ophthalmology, 10/11/2012
Ranibizumab for eyes previously treated with pegaptanib or bevacizumab without clinical response
Kaiser RS, Gupta OP, Regillo CD, Ho AC, Fineman MS, Vander JF, McNamara JA, Brown GC, Ophthalmic Surg Lasers Imaging, 1/1/2012
Ophthalmic Technology Assessment Anti-vascular endothelial growth factor pharmacotherapy for diabetic macular edema A report by the American Academy of Ophthalmology
Ho AC, Scott IU, Kim SJ, Brown GC (methodologist), Brown MM (methodologist), Ip MS, Recchia FM, Ophthalmology, 1/1/2012
Association between high-risk disease Loci and response to anti-vascular endothelial growth factor treatment for wet age-related macular degeneration
Orlin A, Hadley D, Chang W, Ho AC, Brown G, Kaiser RS, Regillo CD, Godshalk AN, Lier A, Kaderli B, Stambolian D, Retina, 1/1/2012
Post-Injection Endophthalmitis (PIE) Study Team Outcomes and risk factors associated with endophthalmitis after intravitreal injection of anti-vascular endothelial gro...
Shah CP, Garg SJ, Vander JF, Brown GC, Kaiser RS, Haller JA, Ophthalmology, 10/1/2011
Comparative effectiveness and cost-effectiveness analyses on the Implantable Miniature Telescope
Brown GC, Brown MM, Lieske HB, Lieske PA, Brown KS, Ophthalmology, 9/1/2011
Psychological and cognitive determinants of vision function in age-related macular degeneration
Rovner BW, Casten RJ, Massof RW, Leiby BE, Tasman WS, Benson WE, Brown GC, Federman JL, Fineman MS, Fischer DH, Garg SJ, Ho AC, Hsu J, Kaiser RS, Lucier AC, Maguire JI..., Arch Ophthalmol, 7/1/2011
Healthcare costs, buyer alert Review
Brown MM, Brown GC, Leiske HB, Lieske PA, Curr Opin Ophthalmol, 5/1/2011
Update on nonsurgical therapy for diabetic macular edema
Witkin AJ, Brown GC, Curr Opin Ophthalmol., 5/1/2011
Diabetes treatment regulation attempt is a portent
Brown GC, Wall Street J, 3/24/2011
Changes in the practice of vitreoretinal disease Editorial
Brown GC, Curr Opin Ophthalmol., 1/1/2011
Editorial Many thanks to all
Brown MM, Brown GC, Kertes P, Stein J, Evidence-Based Ophthalmology, 1/1/2011
Comment on “Walvick MD, Walvick MP Giant cell arteritis: Laboratory predictors of a positive temporal artery biopsy
Shareef R, Brown GC, Ophthalmology, 1/1/2011
Comment on “Walvick MD, Walvick MP Giant cell arteritis: Laboratory predictors of a positive temporal artery biopsy
Shareef R, Brown GC, Evidence-Based Ophthalmology, 1/1/2011
Comment on “Baseline predictors of visual acuity and retinal thickness in patients with retinal vein occlusion: Standard Care Versus Corticosteroid for Retinal Vein Oc...
Roth Z, Brown GC, Ophthalmology, 1/1/2011
Comment on “Baseline predictors of visual acuity and retinal thickness in patients with retinal vein occlusion: Standard Care Versus Corticosteroid for Retinal Vein Oc...
Roth Z, Brown GC, Evidence-Based Ophthalmology, 1/1/2011
Comment on, “Central retinal artery occlusion: Local intra-arterial fibrinolysis versus conservative treatment, a multicenter randomized trial
London N, Brown GC. Comment on, Evidence-Based Ophthalmology, 1/1/2011
Comparative effectiveness and cost-effectiveness analyses: 27,000,000 possible input variants
Brown GC, Brown MM, Kertes P, Evidence-Based Ophthalmology Care, 1/1/2011
Value-Based MedicineR Comparative Effectiveness and Cost-Effectiveness Analyses173% and Counting
Brown GC, Brown MM, Kertes P, Lieske HB, Lieske PA. Brown KS, Evidence-Based Ophthalmol, 1/1/2011
Value-Based MedicineR comparative effectiveness and cost-effectiveness analyses Oral vitamin, and zinc supplements for the treatment of atrophic age-related macular de...
Brown GC, Brown MM, Leiske HB, Leiske AP, Brown KS, Evidence-Based Ophthalmol, 1/1/2011
Value-Based Medicine Analysis Cost-Utility Analysis The foundation of Value-Based Medicine Guidelines to master when performing or evaluating a cost-utility analysis
Brown GC, Brown MM, Kertes P, Stein J, Evidence-Based Ophthalmol, 1/1/2011
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Press Mentions

Treatment Outcomes of Focal Laser Consolidation During Chemoreduction for Group B RetinoblastomaMay 26th, 2020
Utility Values and Age-Related Macular DegenerationJanuary 27th, 2017
Does Quality-of-Life with DME Therapies Have a Price?May 9th, 2016