GeoffreyAlanBlockMD

Nephrology • Denver, CO

Physician

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Office
130 Rampart Way
300-B
Denver, CO 80230
Phone+1 303-364-4775

Fax+1 303-364-4776
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Education & Training

University of Michigan Health SystemFellowship, Nephrology, 1995 - 1997
University of Cincinnati Medical Center/College of MedicineResidency, Internal Medicine, 1991 - 1995
University of Cincinnati College of MedicineClass of 1991

Certifications & Licensure

CO State Medical License 1997 - 2025
WY State Medical License 2020 - 2023
TX State Medical License 2022 - 2023
MI State Medical License 1995 - 1999
OH State Medical License 1992 - 1996
American Board of Internal Medicine Nephrology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification eClinicalWorks EHR, eClinicalWorks LLC, 2012-2013
Fellow (ASNF) American Society of Nephrology

Clinical Trials

Treatment Protocol of Replagal for Patients With Fabry Disease
No longer available
Double Blind Randomized Placebo Controlled Trial of FOSTRAP Chewing Gum in Patients With CKD and Hyperphosphatemia Start of enrollment: 2010 Jan 01
Completed
Phase 1
Salivary Phosphorus and Level of Kidney Function Start of enrollment: 2011 Mar 01
Completed
PD Study to Assess Phosphate Binding Characteristics of K2CG Chewing Gum Start of enrollment: 2011 Jul 01
Completed
Not Applicable
Circadian Rhythm Modulation by Dietary Phosphorus in Chronic Kidney Disease Start of enrollment: 2011 Apr 01
Completed
Not Applicable
Phosphate Binding of Chitosan Chewing Gum in Patients With Chronic Kidney Disease (CKD) Start of enrollment: 2011 Mar 01
Completed
Early Phase 1
Dose Finding Study to Treat High Phosphate Levels in the Blood. Start of enrollment: 2014 Mar 01
Completed
Phase 2
Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D Start of enrollment: 2015 Mar 01
Completed
Phase 3
The BASE Study: Bicarbonate Administration to Stabilize Estimated Glomerular Filtration Rate (eGFR) Start of enrollment: 2015 Oct 01
Completed
Phase 3
A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL Start of enrollment: 2017 Mar 02
Completed
Phase 2, Phase 3
A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX Start of enrollment: 2017 Dec 26
Completed
Phase 2
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Publications & Presentations

PubMed

Tenapanor as Therapy for Hyperphosphatemia in Maintenance Dialysis Patients: Results from the OPTIMIZE Study.
Pagliaro, L., Zhao, S., Edelstein, S., Spiegel, D., Rosenbaum, D., Sprague, S., Weiner, D., Tietjen, D., Pergola, P., Fishbane, S., Block, G., Silva, A., Fadem, S., Ly...> ;Kidney360. 2024 Feb 7
16 citations
One-year safety and efficacy of intravenous etelcalcetide in patients on hemodialysis with secondary hyperparathyroidism.
David A. Bushinsky, Glenn M. Chertow, Sunfa Cheng, Hongjie Deng, Nelson Kopyt, Kevin J. Martin, Anjay Rastogi, Pablo Ureña-Torres, Marc G. Vervloet, Geoffrey A. Block> ;Nephrology, Dialysis, Transplantation. 2020 Oct 1
24 citations
Kidney Functional Magnetic Resonance Imaging and Change in eGFR in Individuals with CKD
Anand Srivastava, Xuan Cai, Jungwha Lee, Wei Li, Brett Larive, Cynthia Kendrick, Jennifer J. Gassman, John P. Middleton, James C. Carr, Kalani L. Raphael, Alfred K. Ch...> ;Clinical Journal of the American Society of Nephrology. 2020 Jun 8
4 citations
Differential effects of phosphate binders on vitamin D metabolism in chronic kidney disease
Charles Ginsberg, Leila R. Zelnick, Geoffrey A. Block, Glenn M. Chertow, Michel Chonchol, Andrew N. Hoofnagle, Bryan Kestenbaum, Ian H. de Boer> ;Nephrology, Dialysis, Transplantation. 2020 Apr 1
18 citations
Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis.
Myles Wolf, Geoffrey A. Block, Glenn M. Chertow, Kerry Cooper, Bruno Fouqueray, Sharon M. Moe, Yan Sun, Holly Tomlin, Marc G. Vervloet, Rainer Oberbauer> ;Clinical Kidney Journal. 2020 Feb 1
32 citations
A Randomized Trial Comparing the Safety, Adherence, and Pharmacodynamics Profiles of Two Doses of Sodium Bicarbonate in CKD: the BASE Pilot Trial.
Kalani L. Raphael, Tamara Isakova, Joachim H. Ix, Dominic S. Raj, Myles Wolf, Linda F. Fried, Jennifer J. Gassman, Cynthia Kendrick, Brett Larive, Michael F. Flessner,...> ;Journal of the American Society of Nephrology. 2020 Jan 1
19 citations
Therapeutic effect of iron citrate in blocking calcium deposition in high pi-calcified VSMC: Role of autophagy and apoptosis
Paola Ciceri, Monica Falleni, Delfina Tosi, Carla Martinelli, Stefania Cannizzo, Giulia Marchetti, Antonella d'Arminio Monforte, Gaetano Bulfamante, Geoffrey A. Block,...> ;International Journal of Molecular Sciences. 2019 Nov 25
30 citations
Serum Calcification Propensity and Clinical Events in CKD.
, , , , , , , , , , , , , , , , > ;Clinical Journal of the American Society of Nephrology. 2019 Oct 28
47 citations
A Pilot Randomized Trial of Ferric Citrate Coordination Complex for the Treatment of Advanced CKD.
Geoffrey A. Block, Martha S. Block, Gerard Smits, Rupal Mehta, Tamara Isakova, Myles Wolf, Glenn M. Chertow> ;Journal of the American Society of Nephrology. 2019 Jul 5
30 citations
Effect of ferric citrate on serum phosphate and fibroblast growth factor 23 among patients with nondialysis-dependent chronic kidney disease: path analyses.
Geoffrey A. Block, Pablo E. Pergola, Steven Fishbane, Julian G. Martins, Robin D. LeWinter, Katrin Uhlig, John F. Neylan, Glenn M. Chertow> ;Nephrology, Dialysis, Transplantation. 2019 Jul 1
67 citations
Effects of Nicotinamide and Lanthanum Carbonate on Serum Phosphate and Fibroblast Growth Factor-23 in CKD: The COMBINE Trial.
Joachim H. Ix, Tamara Isakova, Brett Larive, Kalani L. Raphael, Dominic S. Raj, Alfred K. Cheung, Stuart M. Sprague, Linda F. Fried, Jennifer J. Gassman, John P. Middl...> ;Journal of the American Society of Nephrology. 2019 May 13
8 citations
Etelcalcetide Is Effective at All Levels of Severity of Secondary Hyperparathyroidism in Hemodialysis Patients.
John Cunningham, Geoffrey A. Block, Glenn M. Chertow, Kerry Cooper, Pieter Evenepoel, Jan Iles, Yan Sun, Pablo Ureña-Torres, David A. Bushinsky> ;Kidney International Reports. 2019 Apr 16
7 citations
Influence of Renal Function on Evolocumab Exposure, Pharmacodynamics, and Safety.
Edward Lee, John P. Gibbs, Maurice Emery, Geoffrey A. Block, Scott M. Wasserman, Lisa Hamilton, Sreeneeranj Kasichayanula, Patrick Hanafin, Ransi Somaratne, Ogo Egbuna> ;Clinical Pharmacology in Drug Development. 2019 Apr 1
9 citations
An integrated analysis of safety and tolerability of etelcalcetide in patients receiving hemodialysis with secondary hyperparathyroidism
Geoffrey A. Block, Glenn M. Chertow, John T. Sullivan, Hongjie Deng, Omar Mather, Holly Tomlin, Michael Serenko> ;Plos One. 2019 Mar 15
64 citations
Efficacy and Safety of Tenapanor in Patients with Hyperphosphatemia Receiving Maintenance Hemodialysis: A Randomized Phase 3 Trial.
Geoffrey A. Block, David P. Rosenbaum, Andrew T. Yan, Glenn M. Chertow> ;Journal of the American Society of Nephrology. 2019 Mar 7
26 citations
The effects of tenapanor on serum fibroblast growth factor 23 in patients receiving hemodialysis with hyperphosphatemia.
Geoffrey A. Block, David P. Rosenbaum, Andrew T. Yan, Peter J. Greasley, Glenn M. Chertow, Myles Wolf> ;Nephrology, Dialysis, Transplantation. 2019 Feb 1
55 citations
Effects of vadadustat on hemoglobin concentrations in patients receiving hemodialysis previously treated with erythropoiesis-stimulating agents
Volker H. Haase, Glenn M. Chertow, Geoffrey A. Block, Pablo E. Pergola, Emil M. deGoma, Zeeshan Khawaja, Amit Sharma, Bradley J. Maroni, Peter A. McCullough> ;Nephrology, Dialysis, Transplantation. 2019 Jan 1
12 citations
Effects of bardoxolone methyl on body weight, waist circumference and glycemic control in obese patients with type 2 diabetes mellitus and stage 4 chronic kidney disease.
Glenn M. Chertow, Gerald B. Appel, Geoffrey A. Block, Melanie P. Chin, Daniel W. Coyne, Angie Goldsberry, Kamyar Kalantar-Zadeh, Colin J. Meyer, Mark E. Molitch, Pablo...> ;Journal of Diabetes and Its Complications. 2018 Dec 1
13 citations
Multicenter Study Evaluating Intrarenal Oxygenation and Fibrosis Using Magnetic Resonance Imaging in Individuals With Advanced CKD.
Pottumarthi V. Prasad, Wei Li, Dominic S. Raj, James C. Carr, Maria Carr, Jon Thacker, Lu-Ping Li, Chi Wang, Stuart M. Sprague, Joachim H. Ix, Michel Chonchol, Geoffre...> ;Kidney International Reports. 2018 Jul 7
5 citations
Hemoglobin response to ferric citrate in patients with nondialysis-dependent chronic kidney disease and iron deficiency anemia.
Pablo E. Pergola, Steven Fishbane, Robin D. LeWinter, John F. Neylan, Katrin Uhlig, Geoffrey A. Block, Glenn M. Chertow> ;American Journal of Hematology. 2018 Jun 1
5 citations
Effects of calcimimetics on long-term outcomes in dialysis patients: literature review and Bayesian meta-analysis.
Greta Lozano-Ortega, Nathalie Waser, Mark Bensink, Sarah Goring, Heather Bennett, Geoffrey A. Block, Glenn M. Chertow, Marie-Louise Trotman, Kerry Cooper, Adrian R. Le...> ;Journal of Comparative Effectiveness Research. 2018 May 15
5 citations
The phosphate bucket list.
Tamara Isakova, Geoffrey A. Block> ;Kidney International. 2018 May 1
185 citations
Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder: Synopsis of the Kidney Disease: Improving Global Outcomes 2017 Cl...
Markus Ketteler, Geoffrey A. Block, Pieter Evenepoel, Masafumi Fukagawa, Charles A. Herzog, Linda M. McCann, Sharon M. Moe, Rukshana Shroff, Marcello Tonelli, Nigel D ...> ;Annals of Internal Medicine. 2018 Mar 20
110 citations
Bardoxolone Methyl Improves Kidney Function in Patients with Chronic Kidney Disease Stage 4 and Type 2 Diabetes : Post-Hoc Analyses from Bardoxolone Methyl Evaluation ...
Melanie P. Chin, George L. Bakris, Geoffrey A. Block, Glenn M. Chertow, Angie Goldsberry, Lesley A. Inker, Hiddo J.L. Heerspink, Megan O'Grady, Pablo E. Pergola, Chris...> ;American Journal of Nephrology. 2018 Jan 18
18 citations
The Effect of Extended Release Niacin on Markers of Mineral Metabolism in CKD
Rakesh Malhotra, Ronit Katz, Andrew N. Hoofnagle, Andrew G. Bostom, Dena E. Rifkin, Ruth McBride, Jeffrey L. Probstfield, Geoffrey A. Block, Joachim H. Ix> ;Clinical Journal of the American Society of Nephrology. 2018 Jan 6
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Press Mentions

Phosphates May Make You Feel LazyFebruary 6th, 2019
Experimental Drug Could Help Treat Genetic Disease Affecting the KidneysAugust 10th, 2018
Experimental Drug Keeps Father of Two from Needing Kidney TransplantAugust 6th, 2018
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