GeorgeMillerMD

PubMed

• 63 citations
  Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer.
  Emma Kurz, Carolina Alcantara Hirsch, Tanner Dalton, Sorin Alberto Shadaloey, Alireza Khodadadi-Jamayran, George Miller, Sumedha Pareek, Hajar Rajaei, Chirayu Mohindro...> ;Cancer Cell. 2022 Jul 11
• 22 citations
  Intrahepatic microbes govern liver immunity by programming NKT cells.
  Joshua C Leinwand, Bidisha Paul, Ruonan Chen, Fangxi Xu, Maria A Sierra, Madan M Paluru, Sumant Nanduri, Carolina G Alcantara, Sorin Aa Shadaloey, Fan Yang, Salma A Ad...> ;The Journal of Clinical Investigation. 2022 Apr 15
• 2 citations
  Author Correction: Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.
  Donnele Daley, Vishnu R. Mani, Navyatha Mohan, Neha Akkad, Atsuo Ochi, Daniel W. Heindel, Ki Buom Lee, Constantinos P. Zambirinis, Gautam S.D. Balasubramania Pandian, ...> ;Nature Medicine. 2021 Nov 29
• 11 citations
  Fungi, Host Immune Response and Tumorigenesis
  Miar Elaskandrany, Rohin Patel, Mintoo Patel, George Miller, Deepak Saxena, Anjana Saxena> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2021 Jul 7
• 1 citations
  SSAT State-of-the-Art Conference: Advancements in the Microbiome.
  Miquell O. Miller, Purna C. Kashyap, Sarah Becker, Ryan M. Thomas, Richard A. Hodin, George Miller, Mautin Hundeyin, Smruti Pushalkar, Deirdre Jill Cohen, Deepak Saxen...> ;Journal of Gastrointestinal Surgery. 2021 Jul 1
• 7 citations
  Author Correction: The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression.
  Lena Seifert, Gregor Werba, Shaun Tiwari, Nancy Ngoc Giao Ly, Sara Alothman, Dalia Alqunaibit, Antonina Avanzi, Rocky Barilla, Donnele Daley, Stephanie H. Greco, Aleja...> ;Nature. 2021 Mar 1
• 108 citations
  SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling.
  Carmine Fedele, Shuai Li, Kai Wen Teng, Connor Foster, David H. Peng, Hao Ran, Paolo Mita, Mitchell J. Geer, Takamitsu Hattori, Akiko Koide, Yubao Wang, Kwan Ho Tang, ...> ;The Journal of Experimental Medicine. 2021 Jan 4
• 14 citations
  Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non-Small Cell Lung Cancer.
  Fei Li, Wai-Lung Ng, Troy A. Luster, Hai Hu, Vladislav O. Sviderskiy, Catríona M. Dowling, Kate E.R. Hollinshead, Paula Zouitine, Hua Zhang, Qingyuan Huang, Michela Ra...> ;Cancer Research. 2020 Sep 1
• 31 citations
  Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages
  Ludovic Boytard, Tarik Hadi, Michele Silvestro, Hengdong Qu, Andrew Kumpfbeck, Rayan Sleiman, Kissinger Hyppolite Fils, Dornazsadat Alebrahim, Francesco Boccalatte, Ma...> ;Nature Communications. 2020 Aug 27
• 25 citations
  Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis.
  Loredana Moro, Daniele Simoneschi, Emma Kurz, Arnaldo A. Arbini, Shaowen Jang, Nicoletta Guaragnella, Sergio Giannattasio, Wei Wang, Yu-An Chen, Geoffrey Pires, Andrew...> ;Nature Cell Biology. 2020 Aug 24
• 115 citations
  Regulation and modulation of antitumor immunity in pancreatic cancer.
  Joshua Leinwand, George Miller> ;Nature Immunology. 2020 Aug 17
• 26 citations
  Progress Toward Identifying Exact Proxies for Predicting Response to Immunotherapies.
  Aleksandra Filipovic, George Miller, Joseph Bolen> ;Frontiers in Cell and Developmental Biology. 2020 Mar 17
• 7 citations
  Regulatory T Cells Keep Pancreatic Cancer at Bay.
  Berk Aykut, Ruonan Chen, George Miller> ;Cancer Discovery. 2020 Mar 1
• 57 citations
  Detection of pancreatic ductal adenocarcinoma with galectin-9 serum levels.
  Adrian M. Seifert, Charlotte Reiche, Max Heiduk, Anna Tannert, Ann-Christin Meinecke, Stephanie Baier, Janusz von Renesse, Christoph Kahlert, Marius Distler, Thilo Wel...> ;Oncogene. 2020 Feb 13
• 38 citations
  γδ T Cells Promote Steatohepatitis by Orchestrating Innate and Adaptive Immune Programming.
  Alejandro Torres-Hernandez, Wei Wang, Yuri Nikiforov, Karla Tejada, Luisana E. Torres, Aleksandr Kalabin, Salma Adam, Jingjing Wu, Lu Lu, Ruonan Chen, Aaron Lemmer, Ji...> ;Hepatology. 2020 Feb 1
• 99 citations
  In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma
  Fei Li, Qingyuan Huang, Troy A. Luster, Hai Hu, Hua Zhang, Wai-Lung Ng, Alireza Khodadadi-Jamayran, Wei Wang, Ting Chen, Jiehui Deng, Michela Ranieri, Zhaoyuan Fang, V...> ;Cancer Discovery. 2020 Feb 1
• 121 citations
  CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer
  Hua Zhang, Camilla L. Christensen, Ruben Dries, Matthew G. Oser, Jiehui Deng, Brian Diskin, Fei Li, Yuanwang Pan, Xuzhu Zhang, Yandong Yin, Eleni Papadopoulos, Val Pyo...> ;Cancer Cell. 2020 Jan 13
• 80 citations
  Targeting the interleukin-17 immune axis for cancer immunotherapy.
  Gerardo A. Vitiello, George Miller> ;The Journal of Experimental Medicine. 2020 Jan 6
• 30 citations
  Upregulation of ZIP14 and Altered Zinc Homeostasis in Muscles in Pancreatic Cancer Cachexia.
  Ahmad Rushdi Shakri, Timothy James Zhong, Wanchao Ma, Courtney Coker, Sean Kim, Stephanie Calluori, Hanna Scholze, Matthias Szabolcs, Thomas C. Caffrey, Paul M. Grandg...> ;Cancers. 2019 Dec 18
• 40 citations
  Harnessing the Microbiome for Pancreatic Cancer Immunotherapy.
  Gerardo A. Vitiello, Deirdre Jill Cohen, George Miller> ;Trends in Cancer. 2019 Nov 1
• 366 citations
  The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL
  Berk Aykut, Smruti Pushalkar, Ruonan Chen, Qianhao Li, Raquel Abengozar, Jacqueline I. Kim, Sorin A. A. Shadaloey, Dongling Wu, Pamela Preiss, Narendra Verma, Yuqi Guo...> ;Nature. 2019 Oct 2
• 12 citations
  Microbes as biomarkers and targets in pancreatic cancer.
  Joshua Leinwand, George Miller> ;Nature Reviews. Clinical Oncology. 2019 Sep 17
• 29 citations
  Virome and bacteriome: two sides of the same coin.
  Jonathan Stern, George Miller, Xin Li, Deepak Saxena> ;Current Opinion in Virology. 2019 Aug 1
• Rethinking T cells in pancreas cancer
  Benjamin D. Medina, George Miller> ;Clinical Cancer Research. 2019 Jul 1
• 46 citations
  Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer
  Philip A. Harris, Jill M. Marinis, John D. Lich, Scott B. Berger, Anirudh Chirala, Julie A. Cox, Patrick M. Eidam, Joshua N. Finger, Peter J. Gough, Jae U. Jeong, Jame...> ;ACS Medicinal Chemistry Letters. 2019 May 9
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Journal Articles

• STAT3 Inhibition Induces Bax-Dependent Apoptosis in Liver Tumor Myeloid-Derived Suppressor Cells  
  George Miller, N Joseph Espat, Steven C Katz, Nature
• Mutant Cellular AP-1 Proteins Promote Expression of a Subset of Epstein-Barr Virus Late Genes in the Absence of Lytic Viral DNA Replication  
  George Miller, MD, mBio