HaroldCWiesenfeldMD

Obstetrics & Gynecology • Pittsburgh, PA

Professor of Obstetrics & Gynecology, University Pittsburgh

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Office
300 Halket Street
Suite 2333
Pittsburgh, PA 15213
Phone+1 412-641-1441
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Education & Training

McGill University Faculty Medicine HospitalObstetrics and Gynecology, 1988 - 1990
McGill University Faculty of MedicineClass of 1987

Certifications & Licensure

PA State Medical License 1992 - 2024
American Board of Obstetrics and Gynecology Obstetrics & Gynecology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2009-2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011
Pittsburgh Magazine Castle Connolly, 2008-2011
Fellow (FACOG) American Congress of Obstetricians and Gynecologists
Top MD Consumers Checkbook
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Clinical Trials

Phase I Study of Safety and Persistence of UC-781 Vaginal Microbicide Start of enrollment: 2006 Apr 01
Completed
Phase 1
Chlamydia Trachomatis Immunology and Vaccinology Study Start of enrollment: 2011 Jan 01
Completed
The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID) Start of enrollment: 2010 Nov 01
Completed
Phase 2
Identification of Herpes Simplex Virus (HSV) Shedding in the Female Genital Tract of Pregnant and Nonpregnant Women by GeneXpert PCR, Routine PCR, and Culture Start of enrollment: 2014 Jan 01
Completed
Cepheid Rectal Sample Validation Study Start of enrollment: 2013 Dec 01
Completed
Comparing NAAT Testing to Standard Methods for the Diagnosis of Vaginitis Start of enrollment: 2014 Jul 01
Completed
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Publications & Presentations

PubMed

gen. nov., sp. nov., andsp. nov., gen. nov.: novel bacteria from the familyisolated from the female genital tract.
Sujatha Srinivasan, Michele N Austin, Tina L Fiedler, Susan M Strenk, Kathy J Agnew, G A Nagana Gowda, Daniel Raftery, May A Beamer, Sharon L Achilles, Harold C Wiesen...> ;International Journal of Systematic and Evolutionary Microbiology. 2023 Oct 1
2 citations
Coinfection With Chlamydial and Gonorrheal Infection Among US Adults With Early Syphilis.
Jodie Dionne-Odom, Kimberly Workowski, Charlotte Perlowski, Stephanie N Taylor, Kenneth H Mayer, Candice J McNeil, Matthew M Hamill, Julia C Dombrowski, Teresa A Batte...> ;Sexually Transmitted Diseases. 2022 Aug 1
1 citations
Implementing pre-exposure prophylaxis for HIV prevention in women: the role of the obstetrician-gynecologist.
Sharlay K Butler, Yasaswi Kislovskiy, Katherine Bunge, Harold C Wiesenfeld> ;American Journal of Obstetrics and Gynecology. 2022 Jun 1
2 citations
Genetic susceptibility loci forendometrial infection influence expression of genes involved in T cell function, tryptophan metabolism and epithelial integrity.
Wujuan Zhong, Avinash Kollipara, Yutong Liu, Yuhan Wang, Catherine M O'Connell, Taylor B Poston, Kacy Yount, Harold C Wiesenfeld, Sharon L Hillier, Yun Li, Toni Darvil...> ;Frontiers in Immunology. 2022 Jan 1
1 citations
Multicenter comparison of nucleic acid amplification tests for the diagnosis of rectal and oropharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae infection.
Barbara Van Der Pol, Max Chernesky, Charlotte A. Gaydos, Edward W. Hook, Ajith M. Joseph, Katherine Christensen, Rodney Arcenas, Alexander Boutwell, Harold C. Wiesenfe...> ;Journal of Clinical Microbiology. 2021 Nov 3
2 citations
Contraception Requirements in Clinical Trials: Considerations From Studies on Sexually Transmitted Infections.
Jennifer E. Balkus, Jodie Dionne-Odom, Harold C. Wiesenfeld> ;JAMA. 2021 Nov 23
4 citations
Reduced Endometrial Ascension and Enhanced Reinfection Associated With Immunoglobulin G Antibodies to Specific Chlamydia trachomatis Proteins in Women at Risk for Chla...
Chuwen Liu, Katrin Hufnagel, Catherine M. O'Connell, Nilu Goonetilleke, Neha Mokashi, Tim Waterboer, Tammy S Tollison, Xinxia Peng, Harold C. Wiesenfeld, Sharon L. Hil...> ;The Journal of Infectious Diseases. 2021 Oct 5
15 citations
The Burden of and Trends in Pelvic Inflammatory Disease in the United States, 2006-2016.
Kristen Kreisel, Eloisa Llata, Laura T. Haderxhanaj, William S. Pearson, Guoyu Tao, Harold C. Wiesenfeld, Elizabeth Torrone> ;The Journal of Infectious Diseases. 2021 Aug 16
3 citations
Host Genetic Risk Factors for Chlamydia trachomatis-Related Infertility in Women.
Xiaojing Zheng, Wujuan Zhong, Catherine M. O'Connell, Yutong Liu, Catherine L. Haggerty, William M. Geisler, Gloria E Anyalechi, Robert D. Kirkcaldy, Harold C. Wiesenf...> ;The Journal of Infectious Diseases. 2021 Aug 16
1 citations
The Continued Challenges in the Diagnosis of Acute Pelvic Inflammatory Disease: Focus on Clinically Mild Disease.
David E. Soper, Harold C. Wiesenfeld> ;The Journal of Infectious Diseases. 2021 Aug 16
3 citations
Tubal Factor Infertility, In Vitro Fertilization, and Racial Disparities: A Retrospective Cohort in Two US Clinics.
Gloria E Anyalechi, Harold C. Wiesenfeld, Robert D. Kirkcaldy, Dmitry M. Kissin, Catherine L. Haggerty, Karen R. Hammond, Edward W. Hook, Kyle T. Bernstein, Michael P....> ;Sexually Transmitted Diseases. 2021 Apr 1
3 citations
Chlamydial Pgp3 seropositivity and population attributable fraction among women with tubal factor infertility.
Gloria E Anyalechi, Jaeyoung Hong, Robert D. Kirkcaldy, Harold C. Wiesenfeld, Paddy Horner, Gillian S. Wills, Myra O. McClure, Karen R. Hammond, Catherine L. Haggerty,...> ;Sexually Transmitted Diseases. 2021 Mar 31
Occupational exposures in US obstetrics and gynecology resident physicians.
Alison A. Garrett, Harold C. Wiesenfeld> ;Infection Control and Hospital Epidemiology. 2021 Feb 11
3 citations
Nucleic Acid Amplification Testing Compared With Cultures, Gram Stain, and Microscopy in the Diagnosis of Vaginitis.
Claire S. Danby, Andrew D. Althouse, Sharon L. Hillier, Harold C. Wiesenfeld> ;Journal of Lower Genital Tract Disease. 2021 Jan 1
Evidence is lacking for routine prehysterectomy screening for bacterial vaginosis.
Harold C. Wiesenfeld> ;American Journal of Obstetrics and Gynecology. 2021 Feb 1
7 citations
Adherence to Recommended Practices for Provision of Long-Acting Reversible Contraception Among Providers in a Large U.S. Health Care System
Colleen Judge-Golden, Harold C. Wiesenfeld, Beatrice A. Chen, Sonya Borrero> ;Journal of Women's Health. 2020 Dec 10
2 citations
Many Parents Would Accept Sexually Transmitted Infection Screening for Their Adolescent at a Pediatric Office Visit.
Katherine Lane, Elizabeth Miller, Laura Kisloff, Harold C. Wiesenfeld> ;The Journal of Adolescent Health. 2020 May 1
33 citations
Prevalence of Mycoplasma genitalium infection, antimicrobial resistance mutations and symptom resolution following treatment of urethritis.
Laura H. Bachmann, Robert D. Kirkcaldy, William M. Geisler, Harold C. Wiesenfeld, Lisa E. Manhart, Stephanie N. Taylor, Arlene C. Seña, Candice J. McNeil, Lori M Newma...> ;Clinical Infectious Diseases. 2020 Dec 17
34 citations
A Randomized Controlled Trial of Ceftriaxone and Doxycycline, With or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease
Harold C. Wiesenfeld, Leslie A. Meyn, Toni Darville, Ingrid Macio, Sharon L. Hillier> ;Clinical Infectious Diseases. 2021 Apr 8
17 citations
Sexually Transmitted Infections in Pregnancy and Reproductive Health: Proceedings of the STAR Sexually Transmitted Infection Clinical Trial Group Programmatic Meeting.
Adriane Wynn, Claire C. Bristow, Anthony D. Cristillo, Sara McCurdy Murphy, Nynke van den Broek, Christina A. Muzny, Suhas G. Kallapur, Craig R. Cohen, Robin R. Ingall...> ;Sexually Transmitted Diseases. 2020 Jan 1
25 citations
Cervical cytokines associated with Chlamydia trachomatis susceptibility and protection.
Taylor B. Poston, De’Ashia E. Lee, Toni Darville, Wujuan Zhong, Li Dong, Catherine M. O'Connell, Harold C. Wiesenfeld, Sharon L. Hillier, Gregory D. Sempowski, Xiaojin...> ;The Journal of Infectious Diseases. 2019 Jun 19
17 citations
Anti‐chlamydia IgG and IgA are insufficient to prevent endometrial chlamydia infection in women, and increased anti‐chlamydia IgG is associated with enhanced risk for ...
Toni Darville, Hannah L. Albritton, Wujuan Zhong, Li Dong, Catherine M. O'Connell, Taylor B. Poston, Alison J. Quayle, Nilu Goonetilleke, Harold C. Wiesenfeld, Sharon ...> ;American Journal of Reproductive Immunology. 2019 May 1
16 citations
Susceptibility of endometrial isolates recovered from women with clinical pelvic inflammatory disease or histological endometritis to antimicrobial agents.
M. Petrina, Lisa A. Cosentino, Harold C. Wiesenfeld, Toni Darville, Sharon L. Hillier> ;Anaerobe. 2019 Apr 1
8 citations
Mixed Chlamydia trachomatis Peptide Antigens Provide a Specific and Sensitive Single-Well Colorimetric Enzyme-Linked Immunosorbent Assay for Detection of Human Anti-C....
K. Shamsur Rahman, Toni Darville, Harold C. Wiesenfeld, Sharon L. Hillier, Bernhard Kaltenboeck> ;Msphere. 2018 Dec 26
15 citations
Gene Expression Signatures Can Aid Diagnosis of Sexually Transmitted Infection-Induced Endometritis in Women.
Xiaojing Zheng, Catherine M. O'Connell, Wujuan Zhong, Taylor B. Poston, Harold C. Wiesenfeld, Sharon L. Hillier, Maria Trent, Charlotte A. Gaydos, George C. Tseng, Bra...> ;Frontiers in Cellular and Infection Microbiology. 2018 Sep 20
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Journal Articles

1143Escherichia Coli Antibiotic Resistance Is Driven by Antepartum Antibiotic Exposure
Harold Wiesenfeld, MD, American Journal of Obstetrics and Gynecology
1098 Screening and Infection Rates for Sexually Transmitted Diseases in Pregnant Women with Opioid Use Disorder
Harold Wiesenfeld, Elizabeth Krans, Christina Megli, American Journal of Obstetrics and Gynecology
Evidence Is Lacking for Routine Pre-Hysterectomy Screening for Bacterial Vaginosis
Harold Wiesenfeld, MD, American Journal of Obstetrics and Gynecology

Other

Treatment of pelvic inflammatory disease
Wiesenfeld HC
http://www.uptodate.com/contents/treatment-of-pelvic-inflammatory-disease
UpToDate, Wolters Kluwer Health - 2012-10-24

Press Mentions

What You Need to Know About the Expedited Partner Therapy ActJuly 21st, 2022
Sexually Transmitted Infectious Disease Expert Available to Comment on CDC ReportSeptember 27th, 2017
Screening for Chlamydia Trachomatis Infections in WomenJune 1st, 2017

Grant Support

Importance Of Anti-Anaerobic Therapy For Acute PIDNational Institute Of Allergy And Infectious Diseases2009–2011
Clinical CoreNational Institute Of Allergy And Infectious Diseases2009–2011
Prevention Of Infertility In Women With Subclinical PIDNational Institute Of Allergy And Infectious Diseases2003–2007
Initial Safety Of Cur-Bc10 In Normal WomenNational Center For Research Resources2005
Assessment Of Clinical Performance Of Syscan3 Elisa And Candia5National Center For Research Resources2005
Prevention Of Infertility In Women With Subclinical PIDNational Center For Research Resources2004–2005
Core--Clinical FacilityNational Institute Of Allergy And Infectious Diseases1999–2002
Core--ClinicalNational Institute Of Allergy And Infectious Diseases1999–2002