HowardLevyMD

PubMed

• 217 citations
  A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients wi...
  Jean Louis Vincent, Mayakonda K. Ramesh, David Ernest, Steven P. LaRosa, Jan Pachl, Naoki Aikawa, Eric Hoste, Howard Levy, Joe Hirman, Marcel Levi, Mradul Kumar Daga, ...> ;Critical Care Medicine. 2013 Sep 1
• 49 citations
  CURB-65, PSI, and APACHE II to assess mortality risk in patients with severe sepsis and community acquired pneumonia in PROWESS.
  Guy A. Richards, Howard Levy, Pierre-François Laterre, Charles Feldman, Brad Woodward, Becky Bates, Rebecca L. Qualy> ;Journal of Intensive Care Medicine. 2011 Jan 1
• 3 citations
  Simplified pharmacoeconomics of critical care and severe sepsis.
  Frank R. Ernst, Howard Levy, Rebecca L. Qualy> ;Journal of Intensive Care Medicine. 2007 Sep 1
• 326 citations
  Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial.
  Simon Nadel, Brahm Goldstein, Mark D. Williams, Heidi J. Dalton, Mark J. Peters, William L. Macias, Shamel Abd-Allah, Howard Levy, Robinette Angle, Dazhe Wang, David P...> ;Lancet. 2007 Mar 10
• 134 citations
  Elevated Plasma Concentrations of IL-6 and Elevated APACHE II Score Predict Acute Kidney Injury in Patients with Severe Sepsis
  Lakhmir S. Chawla, Michael G. Seneff, David R. Nelson, Mark E. Williams, Howard Levy, Paul L. Kimmel, William L. Macias> ;Clinical Journal of the American Society of Nephrology. 2006 Nov 2
• 37 citations
  ENHANCE: results of a global open-label trial of drotrecogin alfa (activated) in children with severe sepsis.
  Brahm Goldstein, Simon Nadel, Mark J. Peters, Roger Barton, Flavia Machado, Howard Levy, Douglas J. Haney, Barbara G. Utterback, Mark D. Williams, Brett P. Giroir> ;Pediatric Critical Care Medicine. 2006 May 1
• 586 citations
  Drotrecogin Alfa (Activated) for Adults with Severe Sepsis and a Low Risk of Death
  Edward Abraham, Pierre-François Laterre, Rekha Garg, Howard Levy, Deepak Talwar, Benjamin L. Trzaskoma, Bruno François, Jeffrey S. Guy, Martina Brückmann, Álvaro Réa-N...> ;The New England Journal of Medicine. 2005 Sep 29
• 27 citations
  Application of a population-based severity scoring system to individual patients results in frequent misclassification.
  Frank V. Booth, Mary A Short, Andrew F. Shorr, Nancy Arkins, Becky Bates, Rebecca L. Qualy, Howard Levy> ;Critical Care. 2005 Aug 9
• 14 citations
  Steroid use in PROWESS severe sepsis patients treated with drotrecogin alfa (activated).
  Howard Levy, Pierre-Francois Laterre, Becky Bates, Rebecca L. Qualy> ;Critical Care. 2005 Jul 27
• 146 citations
  Severe community-acquired pneumonia as a cause of severe sepsis: Data from the PROWESS study*
  Pierre-François Laterre, Gary Garber, Howard Levy, Richard G. Wunderink, Gary T. Kinasewitz, Jean-Pierre Sollet, Dennis G. Maki, Becky Bates, Sau Chi Betty Yan, Jean-F...> ;Critical Care Medicine. 2005 May 1
• 16 citations
  Obesity Does Not Alter the Pharmacokinetics of Drotrecogin Alfa (Activated) in Severe Sepsis
  Howard Levy, David S. Small, Darell E. Heiselman, Richard R. Riker, Jay S. Steingrub, Ruqin Chen, Rebecca L. Qualy, Christelle Darstein, Ellen Mongan> ;The Annals of Pharmacotherapy. 2005 Feb 1
• 60 citations
  Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial.
  Pierre-François Laterre, Howard Levy, Gilles Clermont, Daniel E. Ball, Rekha Garg, David R. Nelson, Jean-François Dhainaut, Derek C. Angus> ;Critical Care Medicine. 2004 Nov 1
• 112 citations
  Extended Evaluation of Recombinant Human Activated Protein C United States Trial (ENHANCE US): A Single-Arm, Phase 3B, Multicenter Study of Drotrecogin Alfa (Activated...
  Gordon R. Bernard, Benjamin D. Margolis, Harvey M. Shanies, E. Wesley Ely, Arthur P. Wheeler, Howard Levy, Kar Wong, Theressa J. Wright> ;Chest. 2004 Jun 1
• 4 citations
  Comment: obese man treated with drotrecogin alfa (activated).
  David S. Small, Howard Levy> ;The Annals of Pharmacotherapy. 2004 Apr 1
• 78 citations
  The clinical evaluation committee in a large multicenter phase 3 trial of drotrecogin alfa (activated) in patients with severe sepsis (prowess): Role, methodology, and...
  JF Dhainaut, Pierre-François Laterre, Steven P. LaRosa, Howard Levy, Gary Garber, Darell E. Heiselman, Gary T. Kinasewitz, R. Bruce Light, Peter E. Morris, Roland M. H...> ;Critical Care Medicine. 2003 Sep 1
• 130 citations
  Systemic Host Responses in Severe Sepsis Analyzed by Causative Microorganism and Treatment Effects of Drotrecogin Alfa (Activated)
  Steven M. Opal, Gary Garber, Steven P. LaRosa, Dennis G. Maki, Ross Freebairn, Gary T. Kinasewitz, Jean-François Dhainaut, S. Betty Yan, Mark D. Williams, Delores E. G...> ;Clinical Infectious Diseases. 2003 Jul 1
• 3 citations
  The value of innovation.
  William L. Macias, Howard Levy> ;South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde. 2003 Jul 1
• 8 citations
  Rickettsialpox in a patient with HIV infection
  Scott R. Sanders, Damian Di Costanzo, James Leach, Howard Levy, Krishna Srinivasan, Sherif R. Zaki, James A. Comer, Christopher D. Paddock> ;Journal of the American Academy of Dermatology. 2003 Feb 1
• 207 citations
  Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis.
  Eugene Wesley Ely, Pierre-Francois Laterre, Derek C. Angus, Jeffrey Helterbrand, Howard Levy, Jean-François Dhainaut, Jean Louis Vincent, William L. Macias, Gordon R. ...> ;Critical Care Medicine. 2003 Jan 1
• 66 citations
  Gastric feeding with erythromycin is equivalent to transpyloric feeding in the critically ill.
  Michel Boivin, Howard Levy> ;Critical Care Medicine. 2001 Oct 1
• 46 citations
  Confirming the reliability of the sedation-agitation scale administered by ICU nurses without experience in its use.
  Katherine M. Brandl, Kay A. Langley, Richard R. Riker, Leslie A. Dork, Clifford Qualls, Howard Levy> ;Pharmacotherapy. 2001 Apr 1
• 109 citations
  Treatment of severe systemic inflammatory response syndrome and sepsis with a novel bradykinin antagonist, deltibant (CP-0127). Results of a randomized, double-blind, ...
  Alan M. Fein, Gordon R. Bernard, Gerard J. Criner, Eugene Fletcher, James T. Good, William A. Knaus, Howard Levy, George M. Matuschak, Harvey M. Shanies, Robert W. Tay...> ;JAMA. 1997 Feb 12
• 583 citations
  Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clini...
  Edward Abraham, Richard G. Wunderink, Henry Silverman, Trish M. Perl, Stanley A. Nasraway, Howard Levy, R Bone, Richard P. Wenzel, Robert A. Balk, R Allred> ;JAMA. 1995 Mar 22
• 41 citations
  Rickettsialpox in a New York city hospital, 1980 to 1989
  Elizabeth M. Kass, Wojciech Szaniawski, Howard Levy, James Leach, Krishna Srinivasan, Cornelia Rives> ;The New England Journal of Medicine. 1994 Dec 15
• 31 citations
  A comparative study of oral endotracheal tube securing methods.
  Howard Levy, Linda Griego> ;Chest. 1993 Nov 1
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