HyunJinKimMD

PubMed

• 4 citations
  Synthetic Molecule Libraries for Nucleic Acid Delivery: Design Parameters in Cationic/Ionizable Lipids and Polymers
  Hyun Jin Kim, Ahram Kim, Kanjiro Miyata> ;Drug Metabolism and Pharmacokinetics. 2022 Feb 1
• 2 citations
  Bioinspired Silicification of mRNA-Loaded Polyion Complexes for Macrophage-Targeted mRNA Delivery
  Rimpei Kamegawa, Mitsuru Naito, Satoshi Uchida, Hyun Jin Kim, Beob Soo Kim, Kanjiro Miyata> ;ACS Applied Bio Materials. 2021 Oct 11
• 41 citations
  Improvement of glymphatic-lymphatic drainage of beta-amyloid by focused ultrasound in Alzheimer's disease model.
  Youngsun Lee, Yoori Choi, Eun-Joo Park, Seokjun Kwon, Hyun Kim, Jae Young Lee, Dong Soo Lee> ;Scientific Reports. 2020 Sep 30
• 8 citations
  Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavit...
  Beob Soo Kim, Mitsuru Naito, Hiroyuki Chaya, Mao Hori, Kotaro Hayashi, Hyun Su Min, Yu Yi, Hyun Jin Kim, Tetsuya Nagata, Yasutaka Anraku, Akihiro Kishimura, Kazunori K...> ;Biomacromolecules. 2020 Sep 14
• 1 citations
  Photo-reactive oligodeoxynucleotide-embedded nanovesicles (PROsomes) with switchable stability for efficient cellular uptake and gene knockdown
  Beob Soo Kim, Mitsuru Naito, Rimpei Kamegawa, Hyun Jin Kim, Ryo Iizuka, Takashi Funatsu, Shingo Ueno, Takanori Ichiki, Akihiro Kishimura, Kanjiro Miyata> ;Chemical Communications. 2020 Aug 19
• 89 citations
  Systemic Brain Delivery of Antisense Oligonucleotides across the Blood–Brain Barrier with a Glucose‐Coated Polymeric Nanocarrier
  Hyun Su Min, Hyun Jin Kim, Mitsuru Naito, Satomi Ogura, Kazuko Toh, Kotaro Hayashi, Beob Soo Kim, Shigeto Fukushima, Yasutaka Anraku, Kanjiro Miyata, Kazunori Kataoka> ;Angewandte Chemie. 2020 May 18
• 34 citations
  Fine-Tuning of Hydrophobicity in Amphiphilic Polyaspartamide Derivatives for Rapid and Transient Expression of Messenger RNA Directed Toward Genome Engineering in Brain.
  Hyun Jin Kim, Satomi Ogura, Takahiro Otabe, Rimpei Kamegawa, Moritoshi Sato, Kazunori Kataoka, Kanjiro Miyata> ;ACS Central Science. 2019 Oct 16
• 11 citations
  Dually Stabilized Triblock Copolymer Micelles with Hydrophilic Shell and Hydrophobic Interlayer for Systemic Antisense Oligonucleotide Delivery to Solid Tumor
  Beob Soo Kim, Hyun Jin Kim, Shigehito Osawa, Kotaro Hayashi, Kazuko Toh, Mitsuru Naito, Hyun Su Min, Yu Yi, Ick Chan Kwon, Kazunori Kataoka, Kanjiro Miyata> ;ACS Biomaterials Science & Engineering. 2019 Aug 1
• 8 citations
  Components of Radiologic Progressive Disease Defined by RECIST 1.1 in Patients with Metastatic Clear Cell Renal Cell Carcinoma.
  Heidi Coy, Michael Douek, Kathleen Ruchalski, Hyun Jin Kim, Antonio Gutierrez, Maitrya Patel, Victor Sai, Daniel Margolis, Andrew H. Kaplan, Matthew A. Brown, Jonathan...> ;Radiology. 2019 May 14
• 38 citations
  In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
  Sumiyo Watanabe, Kotaro Hayashi, Kazuko Toh, Hyun Jin Kim, Xueying Liu, Hiroyuki Chaya, Shigeto Fukushima, Keisuke Katsushima, Yutaka Kondo, Satoshi Uchida, Satomi Ogu...> ;Nature Communications. 2019 Apr 24
• 8 citations
  Tunable nonenzymatic degradability of N-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA t...
  Mitsuru Naito, Yuta Otsu, Rimpei Kamegawa, Kotaro Hayashi, Satoshi Uchida, Hyun Jin Kim, Kanjiro Miyata> ;Science and Technology of Advanced Materials. 2019 Feb 13
• 63 citations
  Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-lik...
  Yu Yi, Hyun Jin Kim, Meng Zheng, Peng Mi, Mitsuru Naito, Beob Soo Kim, Hyun Su Min, Kotaro Hayashi, Federico Perche, Kazuko Toh, Xueying Liu, Yuki Mochida, Hiroaki Kin...> ;Journal of Controlled Release. 2019 Feb 10
• 30 citations
  Self-Assembly of siRNA/PEG- b-Catiomer at Integer Molar Ratio into 100 nm-Sized Vesicular Polyion Complexes (siRNAsomes) for RNAi and Codelivery of Cargo Macromolecules.
  Beob Soo Kim, Sayan Chuanoi, Tomoya Suma, Yasutaka Anraku, Kotaro Hayashi, Mitsuru Naito, Hyun Jin Kim, Ick Chan Kwon, Kanjiro Miyata, Akihiro Kishimura, Kazunori Kataoka> ;Journal of the American Chemical Society. 2019 Feb 7
• 24 citations
  Small Delivery Vehicles of siRNA for Enhanced Cancer Targeting
  Hyun Jin Kim, Yu Yi, Ahram Kim, Kanjiro Miyata> ;Biomacromolecules. 2018 Jun 4
• 26 citations
  Tuned Density of Anti-Tissue Factor Antibody Fragment onto siRNA-Loaded Polyion Complex Micelles for Optimizing Targetability into Pancreatic Cancer Cells
  Hyun Su Min, Hyun Jin Kim, Jooyeon Ahn, Mitsuru Naito, Kotaro Hayashi, Kazuko Toh, Beob Soo Kim, Yasuhiro Matsumura, Ick Chan Kwon, Kanjiro Miyata, Kazunori Kataoka> ;Biomacromolecules. 2018 May 16
• 437 citations
  Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair
  Kunwoo Lee, Michael J. Conboy, Hyo Min Park, Fuguo Jiang, Hyun Jin Kim, Mark A. DeWitt, Vanessa A Mackley, Kevin Chang, Anirudh Rao, Colin M. Skinner, Tamanna Shobha, ...> ;Nature Biomedical Engineering. 2017 Oct 2
• 94 citations
  Virus-Mimicking Chimaeric Polymersomes Boost Targeted Cancer siRNA Therapy In Vivo
  Yan Zou, Meng Zheng, Weijing Yang, Fenghua Meng, Kanjiro Miyata, Hyun Jin Kim, Kazunori Kataoka, Zhiyuan Zhong> ;Advanced Materials. 2017 Sep 29
• 4 citations
  Multilayered polyion complexes with dissolvable silica layer covered by controlling densities of cRGD-conjugated PEG chains for cancer-targeted siRNA delivery
  Mitsuru Naito, Ryota Azuma, Hiroyasu Takemoto, Mao Hori, Naoto Yoshinaga, Shigehito Osawa, Rimpei Kamegawa, Hyun Jin Kim, Takehiko Ishii, Nobuhiro Nishiyama, Kanjiro M...> ;Journal of Biomaterials Science. Polymer Edition. 2017 Mar 12
• 61 citations
  Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles.
  Yu Yi, Hyun Jin Kim, Peng Mi, Meng Zheng, Hiroyasu Takemoto, Kazuko Toh, Beob Soo Kim, Kotaro Hayashi, Mitsuru Naito, Yu Matsumoto, Kanjiro Miyata, Kazunori Kataoka> ;Journal of Controlled Release. 2016 Dec 28
• 228 citations
  Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment
  Keisuke Katsushima, Atsushi Natsume, Fumiharu Ohka, Keiko Shinjo, Akira Hatanaka, Norihisa Ichimura, Shinya Sato, Satoru Takahashi, Hiroshi Kimura, Yasushi Totoki, Tat...> ;Nature Communications. 2016 Dec 6
• 274 citations
  Recent progress in development of siRNA delivery vehicles for cancer therapy
  Hyun Jin Kim, Ahram Kim, Kanjiro Miyata, Kazunori Kataoka> ;Advanced Drug Delivery Reviews. 2016 Sep 1
• 31 citations
  Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes
  Haruka Nishida, Yoko Matsumoto, Kei Kawana, R. James Christie, Mitsuru Naito, Beob Soo Kim, Kazuko Toh, Hyun Su Min, Yu Yi, Yu Matsumoto, Hyun Jin Kim, Kanjiro Miyata,...> ;Journal of Controlled Release. 2016 Jun 10
• 36 citations
  siRNA-Loaded Polyion Complex Micelle Decorated with Charge-Conversional Polymer Tuned to Undergo Stepwise Response to Intra-Tumoral and Intra-Endosomal pHs for Exertin...
  Montira Tangsangasaksri, Hiroyasu Takemoto, Mitsuru Naito, Yoshinori Maeda, Daiki Sueyoshi, Hyun Jin Kim, Yutaka Miura, Jooyeon Ahn, Ryota Azuma, Nobuhiro Nishiyama, K...> ;Biomacromolecules. 2016 Jan 11
• 6 citations
  Preparation of Polyion Complex Micelles Using Block Copolymers for SiRNA Delivery.
  Hyun Jin Kim, Meng Zheng, Kanjiro Miyata, Kazunori Kataoka> ;Methods in Molecular Biology. 2016 Jan 1
• Precisely regulated nanoarchitecture comprised of gold nanotemplate and unimer polyion complex for systemic delivery of siRNA.
  Meng Zheng, Hyun Jin Kim, Hiroyasu Takemoto, Kanjiro Miyata, Kazunori Kataoka> ;Journal of Controlled Release. 2015 Sep 10
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