J. WilliamHarbourMD

PubMed

• 30 citations
  Advances in the clinical management of uveal melanoma.
  Richard D Carvajal, Joseph J Sacco, Martine J Jager, David J Eschelman, Roger Olofsson Bagge, J William Harbour, Nicholas D Chieng, Sapna P Patel, Anthony M Joshua, So...> ;Nature Reviews. Clinical Oncology. 2023 Feb 1
• Clinical characteristics and postoperative complications as predictors of radiation toxicity after treatment with I125 Eye Plaque Brachytherapy for Uveal Melanomas.
  Vanessa Peters, Aaron Gurayah, William Jin, Deukwoo Kwon, Wei Zhao, Nirav V Patel, Arnold Markoe, Zelia Correa, Matthew T Studenski, J William Harbour, Stuart E Samuels> ;Brachytherapy. 2022 Sep 19
• 1 citations
  Cyst-like recurrence of retinoblastoma diagnosed by multimodal imaging.
  Noy Ashkenazy, J Daniel Diaz, Eric D Hansen, J William Harbour, Zelia M Correa> ;American Journal of Ophthalmology Case Reports. 2022 Sep 1
• 6 citations
  Translational Epidemiology: An Integrative Approach to Determine the Interplay Between Genetic Ancestry and Neighborhood Socioeconomic Status on Triple Negative Breast...
  Neha Goel, Sina Yadegarynia, Deukwoo Kwon, Susan B Kesmodel, James W Harbour, Erin Kobetz, Nipun Merchant, Daniel A Rodriguez> ;Annals of Surgery. 2022 Sep 1
• 1 citations
  Pseudoangiomatous retinal gliosis (PARG) treated with iodine plaque in patient with chronic retinal detachment.
  Marilyn A Marquez, Jorge Fortun, Prashanth Iyer, J William Harbour, Luis J Haddock> ;American Journal of Ophthalmology Case Reports. 2022 Sep 1
• 8 citations
  Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma.
  Usman Baqai, Timothy J Purwin, Nelisa Bechtel, Vivian Chua, Anna Han, Edward J Hartsough, Jeffim N Kuznetsoff, J William Harbour, Andrew E Aplin> ;Molecular Cancer Research. 2022 Aug 5
• 4 citations
  Gain of Chromosome 6p Correlates with Severe Anaplasia, Cellular Hyperchromasia, and Extraocular Spread of Retinoblastoma.
  Gustav Stålhammar, Aaron Yeung, Pia Mendoza, Sander R Dubovy, J William Harbour, Hans E Grossniklaus> ;Ophthalmology Science. 2022 Mar 1
• 7 citations
  Functional impact of titin (TTN) mutations in ocular surface squamous neoplasia.
  Mak B. Djulbegovic, Vladimir N. Uversky, Carol L. Karp, J. William Harbour> ;International Journal of Biological Macromolecules. 2021 Nov 24
• Waking Up With Cloudy Vision.
  Kay T. Khine, William M Clark, J. William Harbour> ;JAMA Ophthalmology. 2021 Oct 28
• 5 citations
  Structural Protein Analysis of Driver Gene Mutations in Conjunctival Melanoma.
  Mak B. Djulbegovic, Vladimir N. Uversky, J. William Harbour, Anat Galor, Carol L. Karp> ;Genes. 2021 Oct 15
• 8 citations
  Multiregional genetic evolution of metastatic uveal melanoma
  Daniel A. Rodriguez, Jessica Yang, Michael A. Durante, Alexander N. Shoushtari, Stergios J. Moschos, Kazimierz O. Wrzeszczynski, J. William Harbour, Richard D. Carvajal> ;NPJ Genomic Medicine. 2021 Aug 16
• 11 citations
  The AMP-dependent kinase pathway is upregulated in BAP1 mutant uveal melanoma
  Vivian Chua, Anna Han, Nelisa Bechtel, Timothy J. Purwin, Emily Hunter, Connie Liao, J. William Harbour, Andrew E. Aplin> ;Pigment Cell & Melanoma Research. 2021 Aug 12
• Secondary Glaucoma Associated with Intraocular Metastatic Cutaneous Melanoma.
  Jason A Greenfield, Megan Rowlands, J. William Harbour> ;Ophthalmology. Glaucoma. 2021 Jul 20
• Multiple genetically distinct uveal melanomas arise in the same eye of two patients with melanosis oculiUnilateral multifocal uveal melanoma in melanosis oculi
  Sushant Wagley, Peter J. Belin, James J. Dollar, J. William Harbour, Amanda C. Maltry, Prithvi Mruthyunjaya, Amy C. Schefler, Peter H. Tang> ;American Journal of Ophthalmology. 2022 Feb 1
• 3 citations
  Comprehensive assessment of the effect of eye plaque tilt on tumor dosimetry.
  Matthew T. Studenski, Arnold M. Markoe, Stuart E. Samuels, Zelia M. Correa, Elizabeth Bossart, J. William Harbour> ;Brachytherapy. 2021 Jun 28
• 3 citations
  Iris metastasis from breast cancer successfully treated with Abemaciclib and Letrozole.
  Lediana Goduni, Noy Ashkenazy, Eric Hansen, Aixa Soyano-Muller, Zelia M. Correa, J. William Harbour> ;Retinal Cases & Brief Reports. 2021 Jun 11
• 13 citations
  Uphyloplot2: visualizing phylogenetic trees from single-cell RNA-seq data.
  Stefan Kurtenbach, Anthony M. Cruz, Daniel A. Rodriguez, Michael A. Durante, J. William Harbour> ;BMC Genomics. 2021 Jun 5
• Iris Mass in a 14-Month-Old Boy
  Noy Ashkenazy, Scott D. Walter, J. William Harbour> ;JAMA Ophthalmology. 2021 Jul 1
• 1 citations
  Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase.
  Hongzhuang Peng, Joel Cassel, Daniel S. McCracken, Jeremy W. Prokop, Eleonora Sementino, Mitchell Cheung, Paul R. Collop, Alexander Polo, Surbhi Joshi, Jacob P. Mandel...> ;Molecular Cancer Research. 2021 Mar 17
• 1 citations
  PieParty: visualizing cells from scRNA-seq data as pie charts.
  Stefan Kurtenbach, James J. Dollar, Anthony M. Cruz, Michael A. Durante, Christina L. Decatur, J. William Harbour> ;Life Science Alliance. 2021 Mar 5
• 1 citations
  Correction to: BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors
  Anna Han, Timothy J. Purwin, Nelisa Bechtel, Connie Liao, Vivian Chua, Erin L. Seifert, Takami Sato, Zachary T. Schug, David W. Speicher, J. William Harbour, Andrew E....> ;Oncogene. 2021 Jan 28
• 25 citations
  BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors.
  Anna Han, Timothy J. Purwin, Nelisa Bechtel, Connie Liao, Vivian Chua, Erin L. Seifert, Takami Sato, Zachary T. Schug, David W. Speicher, J. William Harbour, Andrew E....> ;Oncogene. 2021 Jan 21
• 3 citations
  Multimodal Imaging in the Diagnosis of Exophytic Juxtapapillary Retinal Capillary Hemangioblastoma
  Jonathan F. Russell, Victor M. Villegas, Stephen G. Schwartz, Christina Y. Weng, Janet L. Davis, Harry W. Flynn, J. William Harbour> ;American Journal of Ophthalmology. 2021 Jan 12
• 2 citations
  Therapeutic Escape in Gαq-mutant Uveal Melanoma: It's a FAK.
  J. William Harbour> ;Clinical Cancer Research. 2021 Jun 1
• 2 citations
  Chimerism involving a RB1 pathogenic variant in monochorionic dizygotic twins with twin-twin transfusion syndrome.
  Anna M. Armitage, Monica A. Kundra, Neda Ghiam, Paldeep S. Atwal, Dayna Morel, Kathleen S. Hruska, Rebecca I. Torene, J. William Harbour, Irman Forghani> ;American Journal of Medical Genetics. Part A. 2021 Jan 1
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Journal Articles

• The genetics of uveal melanoma: an emerging framework for targeted therapy  
  Harbour JW, Pigment Cell Melanoma Res, 1/1/2012
• Commentary: "Bench to bedside in uveal melanoma genetics: the future is now"  
  Harbour JW, Retina Today, 1/1/2010
• Loss of Id2 potentiates the tumorigenic effect of Rb inactivation in a mouse model of retinoblastoma  
  Landreville S, Ma D, Harbour JW., Curr eyes Res, 1/1/2010
• editorial: "Pearls for imaging and diagnosis in ocular oncology"  
  Harbour JW, Retina Today, 1/1/2009
• The 7th edition AJCC staging system for eye cancer: an international language for ophthalmic oncology  
  Ainbinder DJ, Albert DM, Armitage JO, Augsburger JJ, Bechrakis Ne, Boden JH et al, Arch Pathol Lab Med, 1/1/2009
• Interview: "Will my eye cancer metastasize or not?"  
  Harbour JW, 1/1/2008
• Commentary: "Update on uveal melanoma"  
  Harbour JW, 1/1/2008
• Interview: "Cancer stem cells and metastasis"  
  Harbour JW, 1/10/2007
• Commentary: "Molecular prognostic testing in uveal melanoma: has it finally come of age?"  
  Harbour JW, Arch Ophthalmol, 1/1/2007
• Molecular prognostic testing in uveal melanoma  
  Ramaiya KJ, Harbour JW, expert Rev Ophthalmol, 1/1/2007
• Current management of uveal melanoma  
  Ramaiya KJ, Harbour JW, expert Rev Ophthalmol, 1/1/2007
• Commentary: "An update on uveal melanoma"  
  Harbour JW, Review of Ophthalmology, 1/1/2003
• Book review: "Radiotherapy of intraocular and orbital tumors, 2nd revised edition"  
  Harbour JW, Arch Ophthalmol, 1/1/2003
• Solitary fibrous tumor of the orbit  
  Char D, Weidner N, Ahn J, Harbour JW, Orbit, 1/1/1997
• Commentary: "Response of the normal eye to high dose radiotherapy"  
  Harbour JW, Oncology, 1/1/1996
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Books/Book Chapters

• The Molecular Basis of Human Cancer 
  Chapter: Retinoblastoma: Clinical and Molecular Perspectives 
  Harbour JW, Walter SDEditors: Coleman WB.SpringerEdition 2nd,2015
• Clinical Ocular Oncology 
  Chapter: Cellular and Genetic events in Retinal Tumorigenesis 
  Dyer MA, Harbour JWEditors: Singh AD, Damato Be, Pe'er J, Murphree AL, Perry JD.elsevierEdition 2nd,2014
• Orbital Tumors: Diagnosis and Treatment 
  Chapter: Second Primary Tumors in Retinoblastoma 
  Harbour JW, Mohsenin AEditors: Karcioglu ZA.SpringerEdition 2nd,2014
• Ocular Disease: Mechanisms and Management 
  Chapter: Molecular Basis of Low-Penetrance Retinoblastoma 
  Matatall K, Harbour JWEditors: Levin & Albert.2010
• Ocular Disease: Mechanisms and Management 
  Chapter: Uveal Melanoma 
  Correa ZM, Harbour JWEditors: Levin & Albert.2010
• AJCC Cancer Staging Manual 
  Chapter: Malignant Melanoma of the Uvea 
  Harbour JW et alEditors: edge, SB, Byrd, DR, Compton, CC, Fritz, AG, Greene, FL, Trotti A.SpringerEdition 7th,2009
• AJCC Cancer Staging Manual 
  Chapter: Retinoblastoma 
  Harbour JW et alEditors: edge, SB, Byrd, DR, Compton, CC, Fritz, AG, Greene, FL, Trotti A.SpringerEdition 7th,2009
• encyclopedia of Cancer 
  Chapter: Uveal Melanoma 
  ehlers JP, Harbour JWEditors: Schwab M.Edition 2nd,2008
• Principles & Practice of Ophthalmology 
  Chapter: Choroidal Nevus and Melanocytoma 
  Harbour JW, Wickens JEditors: Albert DM and Jakobiec FA.WB SaundersEdition 3rd,2006
• Principles & Practice of Ophthalmology 
  Chapter: Intraocular Lymphoma 
  Harbour JW, Feiner LEditors: Albert DM and Jakobiec FA.WB SaundersEdition 3rd,2006
• Clinical Ocular Oncology 
  Chapter: Cellular and Genetic events in Retinal Tumorigenesis. 
  Dyer MA, Harbour JWEditors: Singh AD, Damato Be, Pe'er J, Murphree AL, Perry JD.elsevier2006
• Clinical Ocular Oncology 
  Chapter: Cancer Genetics 
  Onken MD, Harbour JWEditors: Singh AD, Damato Be, Pe'er J, Murphree AL, Perry JD.elsevier2006
• Retina 
  Chapter: Retinoblastoma 
  Harbour JW, Murphree ALEditors: Ryan SA.elsevierEdition 4th,2006
• Vitreoretinal Surgical Techniques 
  Chapter: Genetic Therapy for Ocular Tumors 
  Onken MD, Harbour JWEditors: Peyman GA, Meffert SA, Conway MD.Taylor & FrancisEdition 2nd,2006
• Vitreoretinal Surgical Techniques 
  Chapter: Molecular Predictive Testing of Uveal Melanoma 
  Harbour JWEditors: Peyman GA, Meffert SA, Conway MD.Taylor & FrancisEdition 2nd,2006
• Uveal melanoma: a model for exploring fundamental cancer biology 
  Chapter: Oncogenes and Tumor Suppressor Genes in Uveal Melanoma. 
  Harbour JWEditors: Jager M, Niederkorn JY, Ksander BR.2004
• Cancer: Principles & Practice of Oncology Review 
  Chapter: Cancer of the Skin and Melanoma. 
  Cornelius LA, Carlson JA, Linette GP, Harbour JWEditors: Govindan R.Lippincott, Williams & WilkinsEdition 1st,2004
• Ophthalmology 
  Chapter: Uveal nevus. 
  Augsburger JJ, Harbour JWEditors: Yanoff M, Duker J.Mosby2003
• Ocular Oncology 
  Chapter: Clinical overview of uveal melanoma: introduction to tumors of the eye. 
  Harbour JWEditors: Albert DM, Polans A.Marcel Dekker2003
• Ocular Tumors in Animals and Humans 
  Chapter: Uveal melanocytic tumors. 
  Moulds JRB, Petersen-Jones S, Peruccio C, Ratto A, Sassani JW, Harbour JWEditors: Peiffer RL, Jr, Simons KB.2002
• Clinical Retina 
  Chapter: Intraocular tumors. 
  Harbour JWEditors: Quillen D, Blodi B.AMA Press2002
• Tumors of the eye and Orbit 
  Chapter: Retinoblastoma: pathogenesis and diagnosis. 
  Harbour JWEditors: Char DH.BC Decker, Inc.2001
• Tumors of the eye And Orbit 
  Chapter: Retinoblastoma: treatment. 
  Harbour JWEditors: Char DH.BC Decker, Inc.2001
• Retina, Vitreous, Macular: A Comprehensive Text 
  Chapter: Intraocular lymphoid tumors. 
  Harbour JW, Char DHEditors: Chang S, Shields J, Green WR.WB Saunders1998
• Ophthalmic Surgery: Principles and Techniques 
  Chapter: Management of intraocular tumors. 
  Harbour JW, Murray TGEditors: Albert D.Blackwell Co.1998
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Abstracts/Posters

• Relationships between clinical features, molecular classification, and driver gene mutation status in uveal melanoma.
  Chao D, Harbour JW, Association for Research in Ophthalmology and Vision Science Annual Meeting, Orlando, FL, 1/1/2014
• Clinical predictors of survival after hepatic arterial chemoembolization for stage IV uveal melanoma.
  Walter SD, Harbour JW, Association for Research in Ophthalmology and Vision Science Annual Meeting, Orlando, FL, 1/1/2014
• Natural history of circumscribed choroidal hemangiomas.
  Ortiz AG, Gonzalez MA, Harbour JW, Ayres B, Association for Research in Ophthalmology and Vision Science Annual Meeting, Orlando, FL, 1/1/2014
• Ciliary body melanocytomas: ultrasonographic characteristics and natural course in 9 patients.
  Tenzel P, Gonzalez MA, Bermudez A, Harbour JW, Association for Research in Vision and Ophthalmology Annual Meeting, Orlando, FL, 1/1/2014
• Factors Associated with Better Ocular and Systemic Outcomes in Primary Vitreoretinal Lymphoma.
  Walter SD, Harbour JW, American Society of Retina Specialists Annual Meeting, San Diego, CA, 1/1/2014
• Incidence and treatment of toxicity following i-125 episcleral plaque brachytherapy for uveal melanoma.
  Badiyan S, Grigsby P, Harbour JW, American Brachytherapy Society Annual Meeting, New Orleans, LA, 1/1/2013
• Association between genetic mutations and clinical outcomes in uveal melanoma.
  Harbour JW, Macula Society Annual Meeting, Dana Point, CA, 1/1/2013
• Association between regression rate and gene expression profile class in uveal melanomas undergoing iodine-125 plaque brachytherapy.
  Rao RC, Badiyan SN, Harbour JW, American Society of Retina Specialists Annual Meeting, Toronto, Canada, 1/1/2013
• Update on the gene expression profile prognostic test for posterior uveal melanoma, iris melanoma and small choroidal melanocytic tumors.
  Harbour JW, International Society of Ocular Oncology Meeting, Cleveland, OH, 1/1/2013
• Mutational landscape in uveal melanoma.
  Harbour JW, International Society of Ocular Oncology Meeting, Cleveland, OH, 1/1/2013
• Patient referred for presumed ring melanoma.
  Harbour JW, International Society of Ocular Oncology Meeting, Cleveland, OH, 1/1/2013
• Acute inflammatory regression of class 1 posterior uveal melanomas following I-125 plaque radiotherapy.
  Chen RW, Harbour JW, American Academy of Ophthalmology Annual Meeting, New Orleans, LA, 1/1/2013
• Risk of metastasis associated with fine needle biopsy in uveal melanoma.
  Harbour JW, Retina Society Annual Meeting, Washington, DC, 1/1/2012
• Correlation between gene expression profile class, cytology, and size of melanocytic uveal tumors evaluated by FNAB.
  Correa ZM, Augsburger JJ, Harbour JW, Association for Research in Ophthalmology and Vision Science Annual Meeting, Fort Lauderdale, FL, 1/1/2011
• Comparative study of oncogenic mutations and standard prognostic risk factors for metastasis in uveal melanomas cell lines established by FNAB.
  Simoes CC, Harbour JW, Halaban R, Bacchiocchi A, Materin MA, Association for Research in Vision and Ophthalmology Annual Meeting, Fort Lauderdale, FL, 1/1/2011
• Safety of pars plana vitrectomy in eyes containing a treated uveal melanoma.
  Rajagopal R, Rao PK, Harbour JW, Association for Research in Ophthalmology and Vision Science Annual Meeting, Fort Lauderdale, FL, 1/1/2011
• Oncogene mutation profiling in ocular melanoma.
  Kim IK, MacConaill L, Palescandolo e, Lu S, Lee Je, Adams S, Van Hummelen P, Daniels A, Garraway L, Harbour JW, Gragoudas eS, International Congress of Ocular Oncology, Buenos Aires, Argentina, 1/1/2011
• Correlation between GeP and other prognostic factors for metastatic death in 205 patients with posterior uveal melanoma evaluated by FNAB.
  Corrêa ZM, Augsburger JJ, Harbour JW, International Congress of Ocular Oncology, Buenos Aires, Argentina, 1/1/2011
• Notch signaling promotes uveal melanoma growth. International Congress of Ocular Oncology.
  eberhart C, ebrahimi K, Schreck K, Bar e, Harbour JW, Handa J, Merbs S, Asnaghi L, International Congress of Ocular Oncology, Buenos Aires, Argentina, 1/1/2011
• Use of a microcatheter to obtain biopsies from uveal melanoma.
  Wilson DJ, Harbour JW, International Congress of Ocular Oncology, Buenos Aires, Argentina, 1/1/2011
• Inactivating mutations in BAP1 in metastasizing class 2 uveal melanomas.
  Harbour JW, Onken MD, Worley WA, Bowcock AM, Roberson e, International Congress of Ocular Oncology, Buenos Aires, Argentina, 1/1/2011
• BAP 1 mutation in two families with uveal melanoma.
  Materin MA, Simoes, Halaban R, Harbour JW, International Congress of Ocular Oncology, Buenos Aires, Argentina, 1/1/2011
• 65-year old woman with diffuse conjunctival neoplasm.
  Harbour JW, International Congress of Ocular Oncology, Buenos Aires, Argentina, 1/1/2011
• The role of fine needle aspiration biopsy in management of uveal melanoma patients.
  Hou P, Harocopos G, Harbour JW, Ylagan LR, 17th International Congress of Cytology, edinburgh, UK, 1/1/2010
• Association between gene expression profile, proliferative index and metastasis in uveal melanoma.
  Harbour JW, Onken MD, Worley LA, Association for Research in Ophthalmology and Vision Science Annual Meeting, Fort Lauderdale, FL, 1/1/2010
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Lectures

• Uveal Melanoma - Current Status and Future Directions. 
  New York, NY - 1/1/2014
• Uveal Melanoma - The Present And The Future. 
  Key Largo, FL - 1/1/2014
• Genetic Prognostication in Uveal Melanoma. 
  Tokyo, Japan - 1/1/2014
• Could FNAB Results Change the Management of Uveal Melanoma? 
  Tokyo, Japan - 1/1/2014
• Retinoblastoma. 
  1/1/2014
• Current Research in Uveal Melanoma. 
  1/1/2014
• Modern Molecular Management Of Uveal Melanoma. 
  1/1/2014
• Tumors And Pseudotumors Of The Retinal Pigment epithelium. 
  1/1/2014
• Uveal Melanoma: Current Status and Future Directions. 
  Loyola University School of Medicine, Chicago, IL - 1/1/2014
• Benign Tumors and Pseudotumors of the Retina and Retinal Pigment epithelium. 
  Loyola University School of Medicine, Chicago, IL - 1/1/2014
• Iris Medulloepithelioma. 
  New York, NY - 1/1/2014
• Molecular Biology of Retinoblastoma. 
  New York, NY - 1/1/2014
• Molecular and Genomic Landscape of Uveal Melanoma. 
  Philadelphia, PA - 1/1/2014
• A tumor on the eye: benign or malignant? 
  Miami, FL - 1/1/2014
• The genomic landscape of ocular (uveal) melanoma: Finally coming into focus. 
  New York, NY - 1/1/2013
• Overview of ocular tumors. 
  Palm Beach, FL - 1/1/2013
• Anti-VeGF therapy in ocular oncology. 
  Miami, FL - 1/1/2013
• BAP1 in uveal melanoma. 
  Las Vegas, NV - 1/1/2013
• Future of genetics in the management of retinal diseases. 
  Miami Beach, FL - 1/1/2013
• The mutational landscape in uveal melanoma: clues to tumorigenesis and targeted therapy. 
  South San Francisco, CA - 1/1/2013
• Optic disc tumor. 
  Seattle, WA - 1/1/2013
• Mutational landscape in uveal melanoma. 
  Seattle, WA - 1/1/2013
• Clinical update on retinoblastoma. 
  Riyadh, Saudi Arabia - 1/1/2013
• Research and genetics update on uveal melanoma. 
  Riyadh, Saudi Arabia - 1/1/2013
• Primary vitreoretinal and uveal lymphomas. 
  Riyadh, Saudi Arabia - 1/1/2013
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Other

• Interview: "A life and death predictor adds to a cancer's strain." 
  Harbour JW, New York Times
  http://www.nytimes.com/2012/07/10/health/genetic-test-changes-game-in-cancer-prognosis.html
  1/9/2012
• Interview: "A molecular test of ocular melanoma." 
  Harbour JW, Charles Adler Show
  1/3/2012
• Interview: "A need to know the worst news you will ever hear." 
  Harbour JW, CBS News Sunday Morning
  http://www.cbsnews.com/8301-3445_162-57556650/a-need-to-know-the-worst-news-you-will-ever-hear/
  1/2/2012
• Interview: "Rethinking retinoblastoma: treatment update." 
  Harbour JW, eyeNet
  1/1/2004
• Interview: "Treating eye cancer." 
  Harbour JW, Coping Magazine
  1/1/2000
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