JacobGardinierScottMDDPhil

PubMed

• Habitat escalated adaptive therapy (HEAT): a phase 2 trial utilizing radiomic habitat-directed and genomic-adjusted radiation dose (GARD) optimization for high-grade s...
  Arash O Naghavi, J M Bryant, Youngchul Kim, Joseph Weygand, Gage Redler, Austin J Sim, Justin Miller, Kaitlyn Coucoules, Lauren Taylor Michael, Warren E Gloria, George...> ;BMC Cancer. 2024 Apr 9
• Author Correction: Molecular patterns identify distinct subclasses of myeloid neoplasia.
  Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Laila Terkawi, Hussein Awada, Olisaemeka D Ogbue, Ramsha Ahmed, Simona Pagliuca, Hassan Awada, Yasuo Kubota, Mi...> ;Nature Communications. 2024 Feb 8
• Neutrophil to lymphocyte ratio (NTLR) predicts local control and overall survival after stereotactic body radiotherapy (SBRT) in metastatic sarcoma.
  Eashwar Somasundaram, Peter M Anderson, Timothy D Smile, Ahmed Halima, James B Broughman, Chandana A Reddy, Shireen Parsai, Jacob G Scott, Timothy Chan, Shauna Campbel...> ;Scientific Reports. 2023 Nov 7
• A clinicogenomic model including GARD predicts outcome for radiation treated patients with HPV+ oropharyngeal squamous cell carcinoma.
  Emily Ho, Loris De Cecco, Stefano Cavalieri, Geoffrey Sedor, Frank Hoebers, Ruud H Brakenhoff, Kathrin Scheckenbach, Tito Poli, Kailin Yang, Jessica A Scarborough, Sha...> ;Medrxiv. 2023 Sep 14
• 1 citations
  Frequency-dependent ecological interactions increase the prevalence, and shape the distribution, of pre-existing drug resistance.
  Jeff Maltas, Dagim Shiferaw Tadele, Arda Durmaz, Christopher D McFarland, Michael Hinczewski, Jacob G Scott> ;Biorxiv. 2024 Mar 11
• Maintaining, masking, and mimicking selection: the interplay of cell-intrinsic and cell-extrinsic effects upon eco-evolutionary dynamics.
  Rowan Barker-Clarke, Jason M Gray, Dagim Shiferaw Tadele, Michael Hinczewski, Jacob G Scott> ;Biorxiv. 2023 Aug 31
• Radio-immune response modelling for spatially fractionated radiotherapy.
  Young-Bin Cho, Nara Yoon, John H Suh, Jacob G Scott> ;Physics in Medicine and Biology. 2023 Aug 7
• Towards Data Driven RT Prescription: Integrating Genomics into RT Clinical Practice.
  Javier F Torres-Roca, G Daniel Grass, Jacob G Scott, Steven A Eschrich> ;Seminars in Radiation Oncology. 2023 Jul 1
• Clinical Nomogram Using Novel Computed Tomography-Based Radiomics Predicts Survival in Patients With Non-Small-Cell Lung Cancer Treated With Stereotactic Body Radiatio...
  Eashwar Somasundaram, Raoul R Wadhwa, Adam Litzler, Rowan Barker-Clarke, Peng Qi, Gregory Videtic, Kevin Stephans, Nathan A Pennell, Daniel Raymond, Kailin Yang, Micha...> ;JCO Clinical Cancer Informatics. 2023 Jun 1
• 2 citations
  Molecular patterns identify distinct subclasses of myeloid neoplasia.
  Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Laila Terkawi, Hussein Awada, Olisaemeka D Ogbue, Ramsha Ahmed, Simona Pagliuca, Hassan Awada, Yasuo Kubota, Mi...> ;Nature Communications. 2023 May 30
• 1 citations
  Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems.
  Sara Hamis, Panu Somervuo, J Arvid Ågren, Dagim Shiferaw Tadele, Juha Kesseli, Jacob G Scott, Matti Nykter, Philip Gerlee, Dmitri Finkelshtein, Otso Ovaskainen> ;Journal of Mathematical Biology. 2023 Apr 5
• Radiotherapy innovation in rare diseases-focusing on the value of single institutional experiences for hypofractionated radiotherapy in soft tissue sarcoma.
  Zachary S Mayo, Nathan Mesko, Lukas Nystrom, Chirag S Shah, Jacob G Scott, Shauna R Campbell> ;Radiotherapy and Oncology. 2023 Jun 1
• 1 citations
  Alamar Blue assay optimization to minimize drug interference and inter-assay viability.
  Mina N Dinh, Masahiro Hitomi, Zahraa A Al-Turaihi, Jacob G Scott> ;Biorxiv. 2023 Mar 19
• 2 citations
  A multimodal analysis of genomic and RNA splicing features in myeloid malignancies.
  Arda Durmaz, Carmelo Gurnari, Courtney E Hershberger, Simona Pagliuca, Noah Daniels, Hassan Awada, Hussein Awada, Vera Adema, Minako Mori, Ben Ponvilawan, Yasuo Kubota...> ;Iscience. 2023 Mar 17
• Inferring density-dependent population dynamics mechanisms through rate disambiguation for logistic birth-death processes.
  Linh Huynh, Jacob G Scott, Peter J Thomas> ;Journal of Mathematical Biology. 2023 Mar 3
• 6 citations
  Early outcomes of ultra-hypofractionated preoperative radiation therapy for soft tissue sarcoma followed by immediate surgical resection.
  Zachary S Mayo, Shireen Parsai, Wafa Asha, Mina Dinh, Nathan Mesko, Lukas Nystrom, Chirag S Shah, Jacob G Scott, Shauna R Campbell> ;Radiotherapy and Oncology. 2023 Mar 1
• 1 citations
  A low-cost, open-source evolutionary bioreactor and its educational use.
  Vishhvaan Gopalakrishnan, Dena Crozier, Kyle J Card, Lacy D Chick, Nikhil P Krishnan, Erin McClure, Julia Pelesko, Drew F K Williamson, Daniel Nichol, Soumyajit Mandal...> ;Elife. 2022 Nov 1
• 1 citations
  A Phenome-Wide Association Study and the Discovery of a New Clinical Spectrum of Hereditary Cancer Genes.
  Kailin Yang, Jacob G Scott> ;JAMA Oncology. 2022 Jun 1
• 2 citations
  Translation of Precision Medicine Research Into Biomarker-Informed Care in Radiation Oncology.
  Jessica A. Scarborough, Jacob G. Scott> ;Seminars in Radiation Oncology. 2022 Jan 1
• Association between biologically effective dose and local control after stereotactic body radiotherapy for metastatic sarcoma.
  Eashwar Somasundaram, Timothy D Smile, Ahmed Halima, James B Broughman, Chandana A Reddy, Shireen Parsai, Jacob G Scott, Chirag Shah, Timothy Chan, Shauna Campbell, Li...> ;Journal of Radiosurgery and SBRT. 2022 Jan 1
• Stability of scRNA-Seq Analysis Workflows is Susceptible to Preprocessing and is Mitigated by Regularized or Supervised Approaches.
  Arda Durmaz, Jacob G Scott> ;Evolutionary Bioinformatics Online. 2022 Jan 1
• 7 citations
  Strategies to Mitigate Chemotherapy and Radiation Toxicities That Affect Eating.
  Peter M Anderson, Stefanie M Thomas, Shauna Sartoski, Jacob G Scott, Kaitlin Sobilo, Sara Bewley, Laura K Salvador, Maritza Salazar-Abshire> ;Nutrients. 2021 Dec 8
• Radiotherapy with genomic-adjusted radiation dose - Authors' reply.
  Jacob G. Scott, Geoffrey Sedor, Jessica A. Scarborough, Michael W. Kattan, Javier F. Torres-Roca> ;The Lancet. Oncology. 2021 Nov 1
• 10 citations
  Quantifying previous SARS-CoV-2 infection through mixture modelling of antibody levels.
  Christian Bottomley, M. Otiende, Sophie Uyoga, Katherine E. Gallagher, Eunice W. Kagucia, Anthony Etyang, Daisy Mugo, John N. Gitonga, Henry K. Karanja, James Nyagwang...> ;Nature Communications. 2021 Oct 26
• 7 citations
  Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma.
  Davis T. Weaver, Kathleen I. Pishas, Drew F. K. Williamson, Jessica A. Scarborough, Stephen L. Lessnick, Andrew Dhawan, Jacob G. Scott> ;Plos Computational Biology. 2021 Oct 18
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Abstracts/Posters

• How Morphologic Features Are Shaped By Underlying Somatic Genotype in MDS
  Jacob Scott, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Can Monosomy 7 be Targeted By Next Generation Cereblon-Modulating Agents?
  Jacob Scott, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

Lectures

• Genotype-Resultant Morphology of Myelodysplastic Syndromes (MDS) 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018