Dr. Grutzendler is on Doximity
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Office
300 George Street
Rm8300G
New Haven, CT 06515Phone+1 203-737-2765- Is this information wrong?
Summary
- Dr. Grutzendler obtained his MD at Universidad Javeriana in Bogota, Colombia where he was born and raised. He completed a medical internship in Internal Medicine and a residency in Neurology at Washington University/Barnes-Jewish Hospital in St. Louis. This was followed by a combined clinical and research fellowship in the Alzheimer Disease Research Center and the Department of Neurobiology at Washington University and further neurobiology research training at the Skirball Institute of New York University. Dr. Grutzendler's clinical interests focus on neurodegenerative disorders with special emphasis in dementias such as Alzheimer's disease. He also leads a research laboratory focused on understanding brain function and the cellular basis of neurological diseases. Specifically he is interested in elucidating cellular and molecular mechanisms of neurodegeneration, development of methods for intravital brain imaging and targeted in vivo cellular manipulation, and translational neuroscience with therapeutics efforts within the field of neurodegeneration and nervous system injury.
Education & Training
- New York University School of MedicinePost-Doctoral Fellowship, Neurobiology Research, 2001 - 2003
- Washington University/B-JH/SLCH ConsortiumFellowship, Dementia/Alzheimer's and Neurobiology , 1998 - 2000
- Washington University/B-JH/SLCH ConsortiumResidency, Neurology, 1995 - 1998
- Washington University/B-JH/SLCH ConsortiumInternship, Internal Medicine, 1994 - 1995
- Pontifical Xavierian UniversityClass of 1991
Certifications & Licensure
- CT State Medical License 2011 - 2025
- IL State Medical License 2004 - 2014
- American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- Connecticut Academy of Science and Engineering, Elected Member 2018
- American Society for Clinical Investigation (Elected member) 2012
- NIH Director's Transformative Research Award 2010
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Publications & Presentations
PubMed
- Single celloptogenetic stimulation by two-photon excitation fluorescence transfer.Lei Tong, Shanshan Han, Yao Xue, Minggang Chen, Fuyi Chen, Wei Ke, Yousheng Shu, Ning Ding, Joerg Bewersdorf, Z Jimmy Zhou, Peng Yuan, Jaime Grutzendler> ;Iscience. 2023 Oct 20
- 1 citationsTREM2 and APOE do not modulate phagocytic clearance of dying cells in the live mammalian brain.Eyiyemisi C Damisah, Anupama Rai, Robert A Hill, Lei Tong, Jaime Grutzendler> ;Biorxiv. 2023 Mar 23
- 33 citationsPLD3 affects axonal spheroids and network defects in Alzheimer's disease.Peng Yuan, Mengyang Zhang, Lei Tong, Thomas M Morse, Robert A McDougal, Hui Ding, Diane Chan, Yifei Cai, Jaime Grutzendler> ;Nature. 2022 Dec 1
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Press Mentions
- Too Phatal: How Microglia, Astrocytes Snuff Out Dying NeuronsJune 26th, 2020
- Immune Cells in the Brain Thought to Trigger Dementia Actually PROTECT Against Alzheimer's, Experts DiscoverMay 19th, 2016
- Yale Alzheimer’s Expert to Speak at Fairfield Senior CenterMay 3rd, 2019
Grant Support
- Vascular Mechanisms Of Neuronal Circuit Disruption In DementiaNational Institute On Aging2011
- Embolus Extravasation: An Alternative Mechanism Of Microvascular RecanalizationNational Heart, Lung, And Blood Institute2011
- Role Of Endothelial Cancer Cell Engulfment During Metastatic Brain InvasionNational Cancer Institute2011
- Embolus Extravasation: An Alternative Mechanism Of Microvascular RecanalizationNational Heart, Lung, And Blood Institute2010
- Zeiss Lsm 710 Confocal MicroscopeNational Center For Research Resources2010
- Vascular Mechanisms Of Neuronal Circuit Disruption In DementiaNational Institute On Aging2007–2010
Other Languages
- Spanish
Hospital Affiliations
- Yale-New Haven HospitalNew Haven, Connecticut
- Hospital of St RaphaelNew Haven, Connecticut
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