JamesAlspaughMD

PubMed

• 2 citations
  Transcriptional Profiles Elucidate Differential Host Responses to Infection withand.
  Zachary E Holcomb, Julie M Steinbrink, Aimee K Zaas, Marisol Betancourt, Jennifer L Tenor, Dena L Toffaletti, J Andrew Alspaugh, John R Perfect, Micah T McClain> ;Journal of Fungi. 2022 Apr 22
• 13 citations
  Sterol-Response Pathways Mediate Alkaline Survival in Diverse Fungi.
  Hannah E. Brown, Calla L. Telzrow, Joseph W. Saelens, Larissa Fernandes, J. Andrew Alspaugh> ;Mbio. 2020 Jun 16
• New Spins on Old Drugs: Enhancing Activity of Antifungals.
  J. Andrew Alspaugh> ;Cell Chemical Biology. 2020 Mar 19
• 23 citations
  Erg6 affects membrane composition and virulence of the human fungal pathogen Cryptococcus neoformans
  Fabiana Freire Mendes de Oliveira, Hugo Costa Paes, Luisa Defranco Ferreira Peconick, Fernanda L. Fonseca, Clara Luna Marina, Anamélia Lorenzetti Bocca, Mauricio Homem...> ;Fungal Genetics and Biology. 2020 Mar 19
• 27 citations
  Chitin: A "Hidden Figure" in the Fungal Cell Wall.
  Hannah E. Brown, Shannon K. Esher, J. Andrew Alspaugh> ;Current Topics in Microbiology and Immunology. 2019 Dec 6
• 3 citations
  A Fungal Arrestin Protein Contributes to Cell Cycle Progression and Pathogenesis.
  Calla L. Telzrow, Connie B. Nichols, Natalia Castro-Lopez, Floyd L. Wormley, J. Andrew Alspaugh> ;Mbio. 2019 Nov 19
• 21 citations
  Roles for Stress Response and Cell Wall Biosynthesis Pathways in Caspofungin Tolerance in.
  Kaila M Pianalto, R Blake Billmyre, Calla L Telzrow, J Andrew Alspaugh> ;Genetics. 2019 Sep 1
• Wortmannin and Wortmannine Analogues from an Undescribed Niesslia sp.
  Dischler, N. M.,Xu, L.,Li, Y.,Nichols, C. B.,Alspaugh, J. A.,Bills, G. F.,Gloer, J. B.> ;J. Nat. Prod.. 2019 Mar 08
• Disseminated Adenovirus Infection After Combined Liver-Kidney Transplantation.
  Hemmersbach-Miller, M.,Bailey, E. S.,Kappus, M.,Prasad, V. K.,Gray, G. C.,Alspaugh, J. A.> ;Front Cell Infect Microbiol. 2018 Dec 14
• HASH(0x3e621a8)
  Paes, H. C.,Derengowski, LDS.,Peconick, LDF.,Albuquerque, P.,Pappas, G. J.,Nicola, A. M.,Silva, FBA.,Vallim, M. A.,Alspaugh, J. A.,Felipe, MSS.,Fernandes, L.> ;Front Cell Infect Microbiol. 2018 Nov 30
• 35 citations
  HDAC genes play distinct and redundant roles in Cryptococcus neoformans virulence
  Fabiana Brandão, Shannon K. Esher, Kyla S. Ost, Kaila M. Pianalto, Connie B. Nichols, Larissa Fernandes, Anamélia Lorenzetti Bocca, Marcio José Poças-Fonseca, J. Andre...> ;Scientific Reports. 2018 Mar 26
• Identification of cyclosporin C from Amphichorda felina using a Cryptococcus neoformans differential temperature sensitivity assay.
  Xu, L.,Li, Y.,Biggins, J. B.,Bowman, B. R.,Verdine, G. L.,Gloer, J. B.,Alspaugh, J. A.,Bills, G. F.> ;Appl. Microbiol. Biotechnol.. 2018 Feb 06
• 33 citations
  Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation
  Kyla S. Ost, Shannon K. Esher, Chrissy M. Leopold Wager, Louise A. Walker, Jeanette Wagener, Carol A. Munro, Floyd L. Wormley, J. Andrew Alspaugh> ;Mbio. 2017 Mar 8
• 2 citations
  Discovery of Ibomycin, a Potent Antifungal Weapon.
  J. Andrew Alspaugh> ;Cell Chemical Biology. 2016 Nov 17
• 97 citations
  New Horizons in Antifungal Therapy
  Kaila M. Pianalto, J. A. Alspaugh> ;Journal of Fungi. 2016 Oct 2
• 2 citations
  Unveiling Protein Kinase A Targets in Cryptococcus neoformans Capsule Formation
  J. Andrew Alspaugh> ;Mbio. 2016 Mar 2
• 19 citations
  Rapid mapping of insertional mutations to probe cell wall regulation in Cryptococcus neoformans.
  Shannon K. Esher, Joshua A. Granek, J. Andrew Alspaugh> ;Fungal Genetics and Biology. 2015 Sep 1
• 14 citations
  Impact of Protein Palmitoylation on the Virulence Potential of Cryptococcus neoformans.
  Connie B. Nichols, Kyla S. Ost, Dayton P. Grogan, Kaila M. Pianalto, Shirin Hasan, J. Andrew Alspaugh> ;Eukaryotic Cell. 2015 Jul 1
• 8 citations
  Fungal morphogenesis.
  Xiaorong Lin, J Andrew Alspaugh, Haoping Liu, Steven Harris> ;Cold Spring Harbor Perspectives in Medicine. 2014 Nov 3
• 76 citations
  Virulence mechanisms and Cryptococcus neoformans pathogenesis.
  J. Andrew Alspaugh> ;Fungal Genetics and Biology. 2015 May 1
• The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host.
  O'Meara, T. R.,Xu, W.,Selvig, K. M.,O'Meara, M. J.,Mitchell, A. P.,Alspaugh, J. A.> ;Mol. Cell. Biol.. 2013 Dec 11
• Restricted substrate specificity for the geranylgeranyl transferase-I enzyme in Cryptococcus neoformans: implications for virulence.
  Selvig, K.,Ballou, E. R.,Nichols, C. B.,Alspaugh, J. A.> ;Eukaryotic Cell. 2013 Sep 6
• Ras1 Acts through Duplicated Cdc42 and Rac Proteins to Regulate Morphogenesis and Pathogenesis in the Human Fungal Pathogen Cryptococcus neoformans.
  Ballou, E. R.,Kozubowski, L.,Nichols, C. B.,Alspaugh, J. A.> ;PLoS Genet.. 2013 Aug
• Two Rac paralogs regulate polarized growth in the human fungal pathogen Cryptococcus neoformans.
  Ballou, E. R.,Selvig, K.,Narloch, J. L.,Nichols, C. B.,Alspaugh, J. A.> ;Fungal Genet. Biol.. 2013 Aug
• 160 citations
  Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of Cryptococcus neoformans
  J. Andrew Alspaugh, Read Pukkila-Worley, Toshiaki Harashima, Lora M. Cavallo, Deanna L. Funnell, Gary M. Cox, John R. Perfect, James W. Kronstad, Joseph Heitman> ;Eukaryotic Cell. 2002 Feb 1
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Journal Articles

• Defects in Intracellular Trafficking of Fungal Cell Wall Synthases Lead to Aberrant Host Immune Recognition  
  James Alspaugh, MD, PLoS One