JamesBurkeMDPhD

PubMed

• Association between results of an amyloid PET scan and healthcare utilization in individuals with cognitive impairment.
  Eric Jutkowitz, Peter Shewmaker, Cassie B Ford, Valerie A Smith, Emily O'Brien, Megan Shepherd-Banigan, Emmanuelle Belanger, Brenda L Plassman, James R Burke, Courtney...> ;Journal of the American Geriatrics Society. 2024 Mar 1
• Elevated Amyloid-β PET Scan and Cognitive and Functional Decline in Mild Cognitive Impairment and Dementia of Uncertain Etiology.
  Plassman, B., Ford, C., Smith, V., DePasquale, N., Korthauer, L., Belanger, E., Shepherd-Banigan, M., Couch, E., Jutkowitz, E., O'Brien, E., Sorenson, C., Wetle, T., V...> ;Journal of Alzheimer's Disease. 2024 Jan 1
• Prevalence and incidence of depressive symptoms and diagnosis of depression as associated with elevated amyloid among Medicare beneficiaries with cognitive impairment.
  Emmanuelle Bélanger, Eric Jutkowitz, Peter Shewmaker, Courtney H Van Houtven, James R Burke, Brenda L Plassman, Megan Shepherd-Banigan, Elyse Couch, Caroline Mills, Te...> ;Journal of Affective Disorders. 2023 Aug 1
• 2 citations
  The Preventing Alzheimer's with Cognitive Training (PACT) randomized clinical trial.
  Jody S Nicholson, Elizabeth M Hudak, Christine B Phillips, Marianne Chanti-Ketterl, Jennifer L O'Brien, Lesley A Ross, Jennifer J Lister, James R Burke, Guy Potter, Br...> ;Contemporary Clinical Trials. 2022 Dec 1
• Amyloid-β PET Scan Results Disclosure and Care-Partner Emotional Well-Being Over Time.
  Megan E Shepherd-Banigan, Cassie B Ford, Valerie A Smith, Emmanuelle Belanger, Terrie T Wetle, Brenda L Plassman, James R Burke, Nicole DePasquale, Emily C O'Brien, Co...> ;Journal of Alzheimer's Disease. 2022 Jan 1
• 9 citations
  Tuberous sclerosis complex is a novel, amyloid-independent tauopathy associated with elevated phosphorylated 3R/4R tau aggregation.
  Andy J Liu, John Ervin, James Burke, Richard O'Brien, Shih-Hsiu J Wang, Lusk, J., Jay B Lusk> ;Acta Neuropathologica Communications. 2022 Mar 3
• 44 citations
  Selectivity Profile of the Tyrosine Kinase 2 Inhibitor Deucravacitinib Compared with Janus Kinase 1/2/3 Inhibitors.
  Anjaneya Chimalakonda, James R. Burke, Lihong Cheng, Ian M. Catlett, Michael Tagen, Qihong Zhao, Aditya Patel, Jun Shen, Ihab G. Girgis, Subhashis Banerjee, John Throup> ;Dermatology and Therapy. 2021 Aug 30
• 46 citations
  Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phas...
  Daniel K. Burns, Robert Alexander, Kathleen A. Welsh-Bohmer, Meredith Culp, Carl Chiang, Janet O'Neil, Rebecca Evans, Patrick Harrigan, Brenda L. Plassman, James R. Bu...> ;The Lancet. Neurology. 2021 Jul 1
• 4 citations
  Assessing the Retinal Microvasculature in Individuals With Early and Late-Onset Alzheimer's Disease.
  Cason B. Robbins, Dilraj S. Grewal, Sandra S. Stinnett, Srinath Soundararajan, Stephen P. Yoon, Andy J Liu, James R. Burke, Sharon Fekrat, Polascik, B., Bryce W Polascik> ;Ophthalmic Surgery, Lasers & Imaging Retina. 2021 Jun 1
• 33 citations
  Discovery of BMS-986202: A Clinical Tyk2 Inhibitor that Binds to Tyk2 JH2.
  Chunjian Liu, James Lin, Charles M. Langevine, Daniel Smith, Jianqing Li, John S. Tokarski, Javed Khan, Max Ruzanov, Joann Strnad, Adriana Zupa-Fernandez, Lihong Cheng...> ;Journal of Medicinal Chemistry. 2021 Jan 14
• 2 citations
  Pharmacodynamics-based approach for efficacious human dose projection of BMS-986260, a small molecule transforming growth factor beta receptor 1 inhibitor.
  Karen E. Parrish, Jesse Swanson, Lihong Cheng, Emily Luk, Paul Stetsko, James Smalley, Yue-Zhong Shu, Jinwen Huang, Jonathan G. Pabalan, Yongnian Sun, Tatyana Zvyaga, ...> ;Biopharmaceutics & Drug Disposition. 2021 Jan 8
• 14 citations
  Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches.
  Hai-Yun Xiao, Ning Li, Jingwu Duan, Bin Jiang, Zhonghui Lu, Khehyong Ngu, Joseph A. Tino, Lisa M. Kopcho, Hao Lu, Jing Chen, Andrew J. Tebben, Steven Sheriff, ChiehYin...> ;Journal of Medicinal Chemistry. 2020 Dec 1
• 7 citations
  Association of OCT Angiography Parameters With Age in Cognitively Healthy Older Adults.
  Atalie C. Thompson, Stephen P. Yoon, James H. Powers, James R. Burke, Dilraj S. Grewal, Sharon Fekrat, Polascik, B., Bryce W Polascik> ;Ophthalmic Surgery, Lasers & Imaging Retina. 2020 Dec 1
• 42 citations
  Convolutional neural network to identify symptomatic Alzheimer's disease using multimodal retinal imaging.
  C Ellis Wisely, Dong Wang, Ricardo Henao, Dilraj S. Grewal, Atalie C. Thompson, Cason B. Robbins, Stephen P. Yoon, Srinath Soundararajan, James R. Burke, Andy J Liu, L...> ;The British Journal of Ophthalmology. 2020 Nov 26
• 4 citations
  Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK.
  Anurag S. Srivastava, Soo S. Ko, Scott H. Watterson, Mark A. Pattoli, Stacey Skala, Lihong Cheng, Mary T. Obermeier, Rodney Vickery, Lorell Discenza, Celia D’Arienzo, ...> ;ACS Medicinal Chemistry Letters. 2020 Sep 16
• 7 citations
  Measurement Properties of the CAPACITY Instrument to Assess Perceived Communication With the Health Care Team Among Care Partners of Patients With Cognitive Impairment.
  Courtney Harold Van Houtven, Steven J. Lippmann, Emmanuelle Belanger, Valerie Smith, Hailey J James, Megan Shepherd-Banigan, Eric Jutkowitz, Emily C. O'Brien, Jennifer...> ;Medical Care. 2020 Sep 1
• 5 citations
  Racially diverse participant registries to facilitate the recruitment of African Americans into presymptomatic Alzheimer's disease studies
  Shelytia Cocroft, Kathleen A. Welsh-Bohmer, Brenda L. Plassman, Marianne Chanti-Ketterl, Henry L. Edmonds, Lisa P. Gwyther, Michelle McCart, Heather MacDonald, Guy G. ...> ;Alzheimer's & Dementia. 2020 Aug 1
• 12 citations
  Longer Term Effects of Diet and Exercise on Neurocognition: 1-Year Follow-up of the ENLIGHTEN Trial.
  James A. Blumenthal, Patrick Smith, Stephanie Mabe, Alan L. Hinderliter, Kathleen A. Welsh-Bohmer, Jeffrey N. Browndyke, P. Murali Doraiswamy, Pao-Hwa Lin, William E. ...> ;Journal of the American Geriatrics Society. 2020 Mar 1
• 4 citations
  A High-Throughput BRET Cellular Target Engagement Assay Links Biochemical to Cellular Activity for Bruton's Tyrosine Kinase.
  L. L. Ong, James D Vasta, L. Monereau, G. Locke, H. Ribeiro, Mark A. Pattoli, Stacey Skala, James R. Burke, Scott H. Watterson, Joseph A. Tino, Poncho Meisenheimer, B....> ;SLAS Discovery. 2020 Feb 1
• 7 citations
  Metabolic and Neurocognitive Changes Following Lifestyle Modification: Examination of Biomarkers from the ENLIGHTEN Randomized Clinical Trial.
  Patrick Smith, Stephanie M Mabe, Andrew Sherwood, P. Murali Doraiswamy, Kathleen A. Welsh-Bohmer, James R. Burke, William E. Kraus, Pao-Hwa Lin, Jeffrey N. Browndyke, ...> ;Journal of Alzheimer's Disease. 2020 Jan 1
• 9 citations
  How Accurately Do Patients and Their Care Partners Report Results of Amyloid-β PET Scans for Alzheimer's Disease Assessment?
  Hailey J James, Courtney Harold Van Houtven, Steven J. Lippmann, James R. Burke, Megan Shepherd-Banigan, Emmanuelle Belanger, Terrie Fox Wetle, Brenda L. Plassman> ;Journal of Alzheimer's Disease. 2020 Jan 1
• 39 citations
  Correlation of OCTA and Volumetric MRI in Mild Cognitive Impairment and Alzheimer's Disease.
  Stephen P. Yoon, Atalie C. Thompson, Christopher D. Calixte, James R. Burke, Jeffrey R. Petrella, Dilraj S. Grewal, Sharon Fekrat, Polascik, B., Bryce W Polascik> ;Ophthalmic Surgery, Lasers & Imaging Retina. 2019 Nov 1
• 120 citations
  Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain.
  James R. Burke, Lihong Cheng, Kathleen M. Gillooly, Joann Strnad, Adriana Zupa-Fernandez, Ian M. Catlett, Yifan Zhang, Elizabeth M. Heimrich, Kim W. McIntyre, Mark D. ...> ;Science Translational Medicine. 2019 Jul 24
• 150 citations
  Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.
  Stephen T. Wrobleski, Moslin Ryan M, Shuqun Lin, Yanlei Zhang, Steven H. Spergel, James Kempson, Tokarski John S, Joann Strnad, Adriana Zupa-Fernandez, Lihong Cheng, D...> ;Journal of Medicinal Chemistry. 2019 Jul 18
• 26 citations
  Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase ...
  Moslin Ryan M, Yanlei Zhang, Stephen T. Wrobleski, Shuqun Lin, Mertzman Michael E, Steven H. Spergel, Tokarski John S, Joann Strnad, Kathleen M. Gillooly, Kim W. McInt...> ;Journal of Medicinal Chemistry. 2019 Jul 17
• Join now to see all