JamesGJakowatzMD

General Surgery • Orange, CA

Surgical Oncology (Other than Breast)

Director, UCI Melanoma Center Professor of Surgery

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Office
101 The City Drive
Bldg 56 Rt 81
Orange, CA 92868
Phone+1 714-456-8171

Fax+1 714-456-7244
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Education & Training

City of Hope National Medical CenterResidency, Surgery, 1983 - 1985
Rush University Medical CenterResidency, Surgery, 1978 - 1983
University of Kansas School of MedicineClass of 1978

Certifications & Licensure

CA State Medical License 1983 - 2026
IL State Medical License 1979 - 1987
American Board of Surgery Surgery

Awards, Honors, & Recognition

Top Doctors:LA Area Castle Connolly, 2013
Top Doctors:San Diego Area Castle Connolly, 2013
Top Doctors:Southern California Castle Connolly, 2012

Publications & Presentations

PubMed

Primary sarcoma of the liver: A nationwide analysis of a rare mesenchymal tumor.
Nicole Finney, Tu Tran, Bima J Hasjim, James Jakowatz, Elaine Chiao, Oliver Eng, Ronald Wolf, Zeljika Jutric, Maki Yamamoto, Thuy B Tran> ;Journal of Surgical Oncology. 2024 Feb 1
Histopathologic Evolution of Melanocytes Associated With Rapid Clinical Progression of Melanoma: Clinicopathologic Presentation of Hyperprogressive Disease in a Patien...
Jocelyn Almanza, Allison Dobry, Samuel Ejadi, James Jakowatz, Bonnie Lee> ;The American Journal of Dermatopathology. 2022 Dec 1
3 citations
Impact of Immediate Surgical Reconstruction Following Wide Local Excision of Malignant Head and Neck Melanoma.
Seung Ah Lee, Emily G. Clark, Maki Yamamoto, James G. Jakowatz, Gregory R. D. Evans, Allison C. Hu> ;Plastic and Reconstructive Surgery. Global Open. 2020 Feb 24
30 citations
Race-, Age-, and Anatomic Site-Specific Gender Differences in Cutaneous Melanoma Suggest Differential Mechanisms of Early- and Late-Onset Melanoma.
Tze-An Yuan, Yunxia Lu, Karen L. Edwards, James G. Jakowatz, Frank L. Meyskens, Feng Liu-Smith> ;International Journal of Environmental Research and Public Health. 2019 Mar 13
14 citations
Phase II study of pazopanib in combination with paclitaxel in patients with metastatic melanoma.
John P. Fruehauf, Monica El-Masry, Katherine Osann, Basmina Parmakhtiar, Maki Yamamoto, James G. Jakowatz> ;Cancer Chemotherapy and Pharmacology. 2018 Jun 25
Evolving paradigm in treatment of Merkel cell carcinoma of the digit from ray resection to wide local excision and flap coverage.
Alex Doermann, James G. Jakowatz, Neil F. Jones> ;Hand. 2015 Apr 7
49 citations
Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma
Lili Yue, Zhi-Ming Huang, Stephen Fong, Stanley P. L. Leong, James G. Jakowatz, Alex Charruyer-Reinwald, Maria L. Wei, Ruby Ghadially> ;Melanoma Research. 2015 Apr 1
18 citations
A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiology.
Kenneth G. Linden, Sancy A. Leachman, Jonathan S. Zager, James G. Jakowatz, Jaye L. Viner, Christine E. McLaren, Ronald J. Barr, Philip M. Carpenter, Wen-Pin Chen, Cra...> ;Cancer Prevention Research. 2014 Mar 10
12 citations
Effects of motion on optical properties in the spatial frequency domain.
John Quan Nguyen, Rolf B. Saager, David J. Cuccia, Kristen M. Kelly, James G. Jakowatz, David Hsiang, Anthony J. Durkin> ;Journal of Biomedical Optics. 2011 Dec 1
8 citations
Phase II clinical trial evaluating docetaxel, vinorelbine and GM-CSF in stage IV melanoma.
Zeynep Eroglu, Kevin M. Kong, James G. Jakowatz, Wolfram E. Samlowski, John P. Fruehauf> ;Cancer Chemotherapy and Pharmacology. 2011 Jul 19
5 citations
Regional differences in the use of sentinel lymph node biopsy for melanoma: a potential quality measure.
Karen T. Lane, Ashley E. Kempf, Cheryl P. Magno, John S. Lane, John Butler, David Hsiang, Sheldon Greenfield, James G. Jakowatz> ;The American Surgeon. 2008 Oct 1
59 citations
Randomized Trial of an Allogeneic Melanoma Lysate Vaccine With Low-Dose Interferon Alfa-2b Compared With High-Dose Interferon Alfa-2b for Resected Stage III Cutaneous ...
Malcolm S. Mitchell, Judith Abrams, John A. Thompson, Mohammed Kashani-Sabet, Ronald C. DeConti, Wen-Jen Hwu, Michael B. Atkins, Eric D. Whitman, Marc S. Ernstoff, Fra...> ;Journal of Clinical Oncology. 2007 May 20
4 citations
Potential drug-drug interaction between interferon alfa-2b and gemfibrozil in a patient with malignant melanoma.
Siu-Fun Wong, James G. Jakowatz, Reza Taheri> ;Clinical Therapeutics. 2005 Dec 1
8 citations
Docetaxel and vinorelbine plus GM-CSF in malignant melanoma.
John P. Fruehauf, Kevin M. Kong, James G. Jakowatz> ;Oncology. 2005 Apr 1
8 citations
Management of Hypertriglyceridemia in Patients Receiving Interferon for Malignant Melanoma
Siu-Fun Wong, James G. Jakowatz, Reza Taheri> ;The Annals of Pharmacotherapy. 2004 Oct 1
Evaluation of nodal patterns for melanoma of the ear.
Adriana Cordova, Francesco Moschella> ;Plastic and Reconstructive Surgery. 2004 Apr 15
39 citations
Ki-67 and p53 Expression in Minimal Deviation Melanomas as Compared with Other Nevomelanocytic Lesions
Joe A Chorny, Ronald J. Barr, Ainura Kyshtoobayeva, James G. Jakowatz, Richard J Reed> ;Modern Pathology. 2003 Jun 1
1 citations
Intra-arterial administration of TNF-α followed by arterial ablation is an effective therapy for a regionally confined TNF-resistant rat mammary adenocarcinoma
Brian D. Badgwell, Daniel Valentino, Edward W. B. Jeffes, Kevin W. Dieffenbach, Sathit B. Dulkanchainun, Robert S. Yamamoto, Gale A. Granger, James G. Jakowatz, Willia...> ;Cancer Immunology, Immunotherapy. 2003 Jan 1
8 citations
Minimal deviation melanoma
Yale D. Podnos, Juan Carlos Jimenez, Kambiz Zainabadi, James G. Jakowatz, Ronald J. Barr> ;Cancer Treatment Reviews. 2002 Oct 1
156 citations
Adjuvant Immunotherapy of Resected, Intermediate-Thickness, Node-Negative Melanoma With an Allogeneic Tumor Vaccine: Overall Results of a Randomized Trial of the South...
Vernon K. Sondak, P. Y. Liu, Ralph J. Tuthill, Raymond A. Kempf, Joseph M. Unger, Jeffrey A. Sosman, John A. Thompson, Geoffrey R. Weiss, Bruce G. Redman, James G. Jak...> ;Journal of Clinical Oncology. 2002 Apr 15
22 citations
Marjolin's ulcer in patients with spinal cord injury.
Ibrahim M. Eltorai, Robert E Montroy, Mark R. Kobayashi, James G. Jakowatz, Paul Guttierez> ;The Journal of Spinal Cord Medicine. 2002 Jan 1
66 citations
MUTANT P53 CORRELATES WITH REDUCED EXPRESSION OF THROMBOSPONDIN-1, INCREASED ANGIOGENESIS, AND METASTATIC PROGRESSION IN MELANOMA
Steven W. Grant, Ainura Kyshtoobayeva, Tom Kurosaki, James G. Jakowatz, John P. Fruehauf> ;Cancer Detection and Prevention. 1998 Jan 1
2 citations
Evaluation and treatment of the patient with early melanoma.
James G. Jakowatz, Frank L. Meyskens> ;Comprehensive Therapy. 1995 Jan 1
38 citations
Increased effectiveness of interferon alfa-2b following active specific immunotherapy for melanoma.
Malcolm S. Mitchell, James G. Jakowatz, William Harel, Grace E. Dean, Lucy Stevenson, William D. Boswell, Susan Groshen> ;Journal of Clinical Oncology. 1994 Feb 1
1 citations
Characteristics of cancer cells in gastrointestinal lavage specimens.
R B Wuerker, I L Gordon, James G. Jakowatz> ;Acta Cytologica. 1993 May 1
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Hospital Affiliations

UCI HealthOrange, California