JamesRPaulsonMD

Family Medicine • Grinnell, IA

Hospice & Palliative Medicine, Sports Medicine (Non-Surgical)

Physician

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Office
217 4th Ave W
Grinnell, IA 50112
Phone(641) 236-7524

Fax(641) 236-7944
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Summary

Dr. James Paulson, MD is a family physician in Grinnell, Iowa. He is currently licensed to practice medicine in Iowa and Michigan. He is affiliated with UnityPoint Health - Grinnell Regional Medical Center.

Education & Training

Cedar Rapids Medical Education FoundationResidency, Family Medicine, 1978 - 1981
Michigan State University College of Human MedicineClass of 1978

Certifications & Licensure

MI State Medical License 1979 - 1983
IA State Medical License 1978 - 2023

Publications & Presentations

PubMed

121 citations
An intrinsic S/G2 checkpoint enforced by ATR
Joshua C. Saldivar, Stephan Hamperl, Michael J. Bocek, Mingyu Chung, Thomas E. Bass, Fernanda Cisneros-Soberanis, Kumiko Samejima, Linfeng Xie, James R. Paulson, Willi...> ;Science. 2018 Aug 24
22 citations
Functional analysis after rapid degradation of condensins and 3D-EM reveals chromatin volume is uncoupled from chromosome architecture in mitosis
Kumiko Samejima, Daniel G Booth, Hiromi Ogawa, James R. Paulson, Linfeng Xie, Cara A. Watson, Melpomeni Platani, Masato T. Kanemaki, William C. Earnshaw> ;Journal of Cell Science. 2018 Feb 15
284 citations
A pathway for mitotic chromosome formation
Johan H. Gibcus, Kumiko Samejima, Anton Goloborodko, Itaru Samejima, Natalia Naumova, Johannes Nuebler, Masato T. Kanemaki, Linfeng Xie, James R. Paulson, William C. E...> ;Science. 2018 Feb 9
16 citations
Kin1 is a plasma membrane‐associated kinase that regulates the cell surface in fission yeast
Angela Cadou, Anne Couturier, Cathy Le Goff, Teresa Soto, Ida Miklós, Matthias Sipiczki, Linfeng Xie, James R. Paulson, José Cansado, Xavier Le Goff> ;Molecular Microbiology. 2010 Sep 1
8 citations
Acetylation of core histones in response to HDAC inhibitors is diminished in mitotic HeLa cells
Jason S. Patzlaff, Edith Terrenoire, Bryan M. Turner, William C. Earnshaw, James R. Paulson> ;Experimental Cell Research. 2010 Aug 1
55 citations
Chemical genetic analysis of the regulatory role of Cdc2p in the S. pombe septation initiation network
Sandra Dischinger, Andrea Krapp, Linfeng Xie, James R. Paulson, Viesturs Simanis> ;Journal of Cell Science. 2008 Mar 15
7 citations
Inactivation of Cdk1/Cyclin B in metaphase-arrested mouse FT210 cells induces exit from mitosis without chromosome segregation or cytokinesis and allows passage throug...
James R. Paulson> ;Chromosoma. 2007 Jan 26
31 citations
Sulfhydryl reagents prevent dephosphorylation and proteolysis of histones in isolated HeLa metaphase chromosomes.
James R. Paulson> ;FEBS Journal. 2005 Mar 3
1 citations
Secretory proteins in the reproductive tract of the snapping turtle, Chelhydra serpentina
Ibrahim Y. Mahmoud, James R. Paulson, M. Dudley, J. S. Patzlaff, A.Y.A. Al-Kindi> ;Comparative Biochemistry and Physiology A-molecular & Integrative Physiology. 2004 Dec 1
6 citations
Acid–Urea Polyacrylamide Slab Gel Electrophoresis of Proteins: Preventing Distortion of Gel Wells during Preelectrophoresis
James R. Paulson, Linda L. Higley> ;Analytical Biochemistry. 1999 Mar 1
42 citations
Evidence that the endogenous histone H1 phosphatase in HeLa mitotic chromosomes is protein phosphatase 1, not protein phosphatase 2A
James R. Paulson, Jason S. Patzlaff, Amy J. Vallis> ;Journal of Cell Science. 1996 Jun 1
12 citations
Okadaic acid induces dephosphorylation of histone H1 in metaphase- arrested HeLa cells
James R. Paulson, Wayne A. Ciesielski, Brian R. Schram, Peter W. Mesner> ;Journal of Cell Science. 1994 Jan 1
7 citations
Rapid analysis of mitotic histone H1 phosphorylation by cationic disc electrophoresis at neutral pH in minigels.
James R. Paulson, Peter W. Mesnet, Jeffrey J. Delrow, Najjia N. Mahmoud, Wayne A. Ciesielski> ;Analytical Biochemistry. 1992 Jun 1
12 citations
Scaffold morphology in histone-depleted HeLa metaphase chromosomes
James R. Paulson> ;Chromosoma. 1989 Jan 1
19 citations
Isolation of chromosome clusters from metaphase-arrested HeLa cells.
James R. Paulson> ;Chromosoma. 1982 Jan 1
The structure of histone-depleted metaphase chromosomes.
Paulson, J. R., Laemmli, U. K.> ;Cell. 1977 Nov
Low angle x-ray diffraction studies of chromatin structure in vivo and in isolated nuclei and metaphase chromosomes.
Langmore, J. P., Paulson, J. R.> ;J Cell Biol. 1983 Apr
Isolation of a protein scaffold from mitotic HeLa cell chromosomes.
Adolphs, K. W., Cheng, S. M., Paulson, J. R., Laemmli, U. K.> ;Proc Natl Acad Sci USA. 1977 Nov
Metaphase chromosome structure: the role of nonhistone proteins.
Laemmli, U. K., Cheng, S. M., Adolph, K. W., Paulson, J. R., Brown, J. A., Baumbach, W. R.> ;Cold Spring Harb Symp Quant Biol. 1978
Phosphorylation of histones 1 and 3 and nonhistone high mobility group 14 by an endogenous kinase in HeLa metaphase chromosomes.
Paulson, J. R., Taylor, S. S.> ;J Biol Chem. 1982 Jun 10
Low angle x-ray diffraction studies of HeLa metaphase chromosomes: effects of histone phosphorylation and chromosome isolation procedure.
Paulson, J. R., Langmore, J. P.> ;J Cell Biol. 1983 Apr
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Grant Support

Why Is Histone Acetylation Reduced At Mitosis?National Institute Of General Medical Sciences1992
Are Histone Acetylation Sites Masked During Mitosis?Fogarty International Center1992
Phosphohistone Phosphatase Of Mitotic Hela CellsNational Institute Of General Medical Sciences1988

Hospital Affiliations

UnityPoint Health - Grinnell Regional Medical CenterGrinnell, Iowa